<\/p>\n
Lorfast Meltab<\/strong> \u0435 \u043c\u0430\u0440\u043a\u0430 \u043d\u0430 loratadine<\/strong> (10 mg), a second-generation, non-sedating oral antihistamine<\/strong> \u0438\u0437\u043f\u043e\u043b\u0437\u0432\u0430 \u0441\u0435 \u0437\u0430 hay fever (allergic rhinitis), chronic idiopathic urticaria (hives), itchy skin, and allergic conjunctivitis<\/strong>. It blocks histamine H1 receptors in the peripheral tissues that drive allergy symptoms — sneezing, runny nose, itchy eyes, skin hives — without crossing the blood-brain barrier meaningfully, so it does not make most people drowsy. Onset: 1–3 hours; duration: 24 hours. Once-daily dosing. The most widely used OTC antihistamine worldwide; extremely low drowsiness profile but somewhat weaker anti-itch effect than cetirizine or levocetirizine. Safe for long-term daily use (months to years) in most adults. Common side effects: mild headache, dry mouth, fatigue. Avoid in known hypersensitivity; dose-reduce in significant renal impairment.<\/p>\n<\/div>\n \ud83d\udce6 \u0412\u0441\u044f\u043a\u0430 \u043f\u043e\u0440\u044a\u0447\u043a\u0430 \u0435 \u043f\u043e\u043a\u0440\u0438\u0442\u0430 \u043e\u0442 \u043d\u0430\u0448\u0430\u0442\u0430 \u041f\u043e\u043b\u0438\u0442\u0438\u043a\u0430 \u0437\u0430 \u043f\u043e\u0432\u0442\u043e\u0440\u043d\u0430 \u0438\u0437\u043f\u0440\u0430\u0442\u043a\u0430<\/strong><\/a> \u2014 \u0430\u043a\u043e \u0432\u0430\u0448\u0430\u0442\u0430 \u043f\u0440\u0430\u0442\u043a\u0430 \u043d\u0435 \u043f\u0440\u0438\u0441\u0442\u0438\u0433\u043d\u0435 \u0432 \u0440\u0430\u043c\u043a\u0438\u0442\u0435 \u043d\u0430 20 \u0440\u0430\u0431\u043e\u0442\u043d\u0438 \u0434\u043d\u0438, \u043d\u0438\u0435 \u044f \u0438\u0437\u043f\u0440\u0430\u0449\u0430\u043c\u0435 \u043e\u0442\u043d\u043e\u0432\u043e.<\/p>\n \u041d\u0430\u0448\u0438\u0442\u0435 \u0433\u0435\u043d\u0435\u0440\u0438\u0447\u043d\u0438 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0430 \u0441\u0435 \u0434\u043e\u0441\u0442\u0430\u0432\u044f\u0442 \u043e\u0442 \u043f\u0440\u043e\u0438\u0437\u0432\u043e\u0434\u0438\u0442\u0435\u043b\u0438, \u0441\u0435\u0440\u0442\u0438\u0444\u0438\u0446\u0438\u0440\u0430\u043d\u0438 \u043e\u0442 WHO-GMP, \u0438 \u0441\u0435 \u0438\u0437\u043f\u0440\u0430\u0449\u0430\u0442 \u043f\u043e \u0446\u0435\u043b\u0438\u044f \u0441\u0432\u044f\u0442 \u0432 \u0434\u0438\u0441\u043a\u0440\u0435\u0442\u043d\u0430, \u043e\u0431\u0438\u043a\u043d\u043e\u0432\u0435\u043d\u0430 \u043e\u043f\u0430\u043a\u043e\u0432\u043a\u0430 \u2014 \u0431\u0435\u0437 \u0438\u043c\u0435 \u043d\u0430 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u043e\u0442\u043e \u0432\u044a\u043d\u0448\u043d\u043e \u043d\u0430 \u043f\u0440\u0430\u0442\u043a\u0430\u0442\u0430. \u041f\u043b\u0430\u0449\u0430\u043d\u0438\u044f\u0442\u0430 \u0441 \u043a\u0430\u0440\u0442\u0430 \u0441\u0435 \u043e\u0431\u0440\u0430\u0431\u043e\u0442\u0432\u0430\u0442 \u0447\u0440\u0435\u0437 \u0440\u0435\u0433\u0443\u043b\u0438\u0440\u0430\u043d \u043f\u0440\u043e\u0446\u0435\u0441\u043e\u0440 (\u043e\u043f\u0438\u0441\u0430\u043d\u0438\u0435\u0442\u043e \u043d\u0430 \u0438\u0437\u0432\u043b\u0435\u0447\u0435\u043d\u0438\u0435\u0442\u043e \u0432\u043a\u043b\u044e\u0447\u0432\u0430 \u0440\u0435\u0433\u0443\u043b\u0438\u0440\u0430\u043d \u043f\u0440\u043e\u0446\u0435\u0441\u043e\u0440 \u0437\u0430 \u043f\u043b\u0430\u0449\u0430\u043d\u0435 \u0441 \u043a\u0430\u0440\u0442\u0430 \u2014 \u043d\u0438\u043a\u043e\u0433\u0430 \u201cMedsBase\u201d \u0438\u043b\u0438 \u0438\u043c\u0435 \u043d\u0430 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u043e). \u041f\u0440\u0438\u0435\u043c\u0430\u0442 \u0441\u0435 \u0441\u044a\u0449\u043e \u043a\u0440\u0438\u043f\u0442\u043e\u0432\u0430\u043b\u0443\u0442\u0438 \u0438 \u0431\u0430\u043d\u043a\u043e\u0432 \u043f\u0440\u0435\u0432\u043e\u0434 SEPA. \u0412\u0441\u044f\u043a\u0430 \u043f\u043e\u0440\u044a\u0447\u043a\u0430 \u0435 \u043f\u043e\u0434\u043a\u0440\u0435\u043f\u0435\u043d\u0430 \u043e\u0442 \u043d\u0430\u0448\u0430\u0442\u0430 \u043f\u043e\u043b\u0438\u0442\u0438\u043a\u0430 \u0437\u0430 \u0433\u0430\u0440\u0430\u043d\u0442\u0438\u0440\u0430\u043d\u043e \u043f\u0440\u0435\u0438\u0437\u043f\u0440\u0430\u0449\u0430\u043d\u0435.<\/p>\n Lorfast Meltab is an oral antihistamine containing loratadine<\/strong> (10 mg), supplied as orally dissolving (meltab) tablets. Manufactured by WHO-GMP certified manufacturer, in packs of 30, 60, 90 or 180 tablets. Originator brand: Claritin (Bayer \/ Schering-Plough, 1993).<\/p>\n loratadine belongs to the second-generation (non-sedating) H1 antihistamine class<\/strong> — developed to keep the allergy-blocking effect of older drugs like diphenhydramine or pheniramine while removing the sedation, dry mouth, and cognitive impairment caused by their passage into the brain. Second-generation agents are the first-line oral antihistamines for allergic rhinitis and chronic urticaria in every major allergy guideline (ARIA, EAACI, AAAAI).<\/p>\n \u041d\u0435 \u0435 \u043d\u0435<\/strong> a treatment for anaphylaxis (use adrenaline\/epinephrine auto-injector), asthma (use inhaled corticosteroid + bronchodilator), or allergic food reactions beyond mild skin symptoms.<\/p>\n When you are exposed to an allergen (pollen, dust, animal dander), mast cells and basophils in the skin and mucosa release \u0445\u0438\u0441\u0442\u0430\u043c\u0438\u043d<\/strong>. Histamine binds H1 receptors and causes the classic allergy cascade: vasodilation, vascular leakage, itch, sneeze, increased mucus secretion, and smooth-muscle contraction.<\/p>\n loratadine is a selective inverse agonist at H1 receptors<\/strong>. It stabilises the receptor in its inactive state, reducing signalling even at baseline histamine levels. Key features of the second-generation class:<\/p>\n \u0421\u0442\u0430\u043d\u0434\u0430\u0440\u0442\u043d\u0430 \u0434\u043e\u0437\u0430:<\/strong> 10 mg once daily in adults and children aged 12+. Children 2–11 and <30 kg: 5 mg once daily. Can be taken with or without food.<\/p>\n Minimal sedation<\/strong> — among the least drowsy 2nd-generation antihistamines; sedation rates in large trials are similar to placebo at the 10 mg dose.<\/p>\n Common (< 5% in most trials):<\/strong><\/p>\n \u041d\u0435\u0447\u0435\u0441\u0442\u043e \u0441\u0440\u0435\u0449\u0430\u043d\u0438:<\/strong><\/p>\n \u0411\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0441\u0442:<\/strong> Loratadine is one of two first-line antihistamines in pregnancy<\/strong> (alongside cetirizine) in ACOG and ASCIA guidelines. Large cohort data show no excess risk of major birth defects.<\/p>\n \u041a\u044a\u0440\u043c\u0435\u043d\u0435:<\/strong> second-generation antihistamines pass into breast milk in tiny amounts and are considered compatible with breastfeeding. Loratadine and cetirizine have the most data.<\/p>\n \u0414\u0435\u0446\u0430:<\/strong> Approved from age 2 years (5 mg syrup); 10 mg tablet from age 12.<\/p>\n Store Lorfast Meltab below 25°C in a dry place, in the original blister. Keep out of reach of children.<\/p>\n Yes — Lorfast Meltab contains the active ingredient loratadine. Bioequivalence to the originator brand (Claritin (Bayer \/ Schering-Plough, 1993)) is required by regulatory authorities, so clinical effect is the same at the same dose.<\/p>\n All three are effective for allergic rhinitis and chronic urticaria. Cetirizine is generally the most potent<\/strong> (best for itch\/hives) but causes drowsiness in about 10% of users. Fexofenadine is the least sedating<\/strong> (zero BBB penetration). Loratadine sits between them<\/strong> — very non-drowsy but weaker than cetirizine for itchy skin. For hay fever, pick whichever suits; for hives\/itch, cetirizine often works best; for people who need to drive\/operate machinery, fexofenadine is safest.<\/p>\n Minimal sedation<\/strong> — among the least drowsy 2nd-generation antihistamines; sedation rates in large trials are similar to placebo at the 10 mg dose. If you do feel drowsy, take your dose in the evening, or switch to fexofenadine (the least-sedating 2nd-generation antihistamine).<\/p>\n Yes — long-term daily use of 2nd-generation antihistamines is well-studied and safe for most adults. There is no tachyphylaxis<\/strong> (the effect does not fade), no cumulative organ toxicity, and no withdrawal syndrome. Chronic urticaria patients often take an antihistamine daily for years.<\/p>\n Yes, in most cases. Combining an oral antihistamine with an intranasal corticosteroid (e.g. mometasone, fluticasone) is the standard combination for moderate hay fever<\/strong>. Eye drops (olopatadine, ketotifen) can be added for eye symptoms. Avoid combining two oral antihistamines at the same time without medical advice.<\/p>\n Onset is usually 1–3 hours, with peak effect at 8–12 hours. For seasonal hay fever, starting 1–2 weeks before your usual trigger season gives the best control.<\/p>\n Single-dose overdoses of 2nd-generation antihistamines rarely cause serious harm at a few multiples of the standard dose, but can cause drowsiness, tachycardia, and (rarely) QT prolongation. Seek medical advice if more than 5× the standard dose has been taken, especially in children.<\/p>\n You can order Lorfast Meltab (10 mg) from MedsBase in packs of 30, 60, 90 or 180 tablets. We ship worldwide with discreet packaging and genuine WHO-GMP certified manufacturer stock.<\/p>\n <\/p>\n \u0414\u0440\u0443\u0433\u0438 \u043f\u0440\u043e\u0434\u0443\u043a\u0442\u0438 \u0432 \u0425\u0440\u043e\u043d\u0438\u0447\u043d\u0438 \u0437\u0430\u0431\u043e\u043b\u044f\u0432\u0430\u043d\u0438\u044f<\/strong> \u043a\u043e\u0438\u0442\u043e \u043a\u043b\u0438\u0435\u043d\u0442\u0438\u0442\u0435 \u0441\u044a\u0449\u043e \u0440\u0430\u0437\u0433\u043b\u0435\u0436\u0434\u0430\u0442:<\/p>\n \u2705 Allergy relief Lorfast Meltab contains Loratadine.<\/p>","protected":false},"featured_media":58452,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3975],"product_tag":[3683,4495],"class_list":{"0":"post-58451","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-hay-fever-allergies-treatment","9":"product_tag-loratadine","10":"product_tag-lorfast-meltab","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product\/58451","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/comments?post=58451"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/media\/58452"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/media?parent=58451"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product_brand?post=58451"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product_cat?post=58451"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product_tag?post=58451"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}\u0417\u0430\u0449\u043e \u0434\u0430 \u043f\u043e\u0440\u044a\u0447\u0432\u0430\u0442\u0435 \u043e\u0442 MedsBase<\/h3>\n
What Is Lorfast Meltab?<\/h2>\n
What Is Lorfast Meltab Used For?<\/h2>\n
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How Does Lorfast Meltab Work?<\/h2>\n
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\u0414\u043e\u0437\u0438\u0440\u0430\u043d\u0435 \u0438 \u043f\u0440\u0438\u043b\u0430\u0433\u0430\u043d\u0435<\/h2>\n
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\u0421\u0442\u0440\u0430\u043d\u0438\u0447\u043d\u0438 \u0435\u0444\u0435\u043a\u0442\u0438<\/h2>\n
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\u041b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0435\u043d\u0438 \u0432\u0437\u0430\u0438\u043c\u043e\u0434\u0435\u0439\u0441\u0442\u0432\u0438\u044f<\/h2>\n
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Use in Pregnancy and Children<\/h2>\n
Who Should Not Take Lorfast Meltab?<\/h2>\n
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\u0421\u044a\u0445\u0440\u0430\u043d\u0435\u043d\u0438\u0435<\/h2>\n
\u0427\u0435\u0441\u0442\u043e \u0437\u0430\u0434\u0430\u0432\u0430\u043d\u0438 \u0432\u044a\u043f\u0440\u043e\u0441\u0438<\/h2>\n
Is Lorfast Meltab the same as loratadine?<\/h3>\n
Loratadine vs cetirizine vs fexofenadine — which is best?<\/h3>\n
Will Lorfast Meltab make me drowsy?<\/h3>\n
Is it safe to take Lorfast Meltab every day for months or years?<\/h3>\n
Can I take Lorfast Meltab with other allergy medications?<\/h3>\n
How quickly does Lorfast Meltab work?<\/h3>\n
What happens if I take more than the recommended dose?<\/h3>\n
Where can I buy Lorfast Meltab online?<\/h3>\n
Related Allergy Medications<\/h2>\n
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\u0421\u0432\u044a\u0440\u0437\u0430\u043d\u0438 \u0430\u043b\u0442\u0435\u0440\u043d\u0430\u0442\u0438\u0432\u0438<\/h3>\n
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\n\u2705 \u0424\u043e\u0440\u043c\u0443\u043b\u0430 \u0431\u0435\u0437 \u0441\u044a\u043d\u043b\u0438\u0432\u043e\u0441\u0442
\n\u2705 Rapid dissolving tablets
\n\u2705 Long-lasting action
\n\u2705 Blocks histamine<\/p>\n