{"id":58731,"date":"2024-02-28T05:25:22","date_gmt":"2024-02-28T05:25:22","guid":{"rendered":"https:\/\/medsname.com\/endace\/"},"modified":"2026-04-30T10:24:09","modified_gmt":"2026-04-30T10:24:09","slug":"endace","status":"publish","type":"product","link":"https:\/\/medsbase.com\/bg\/product\/endace\/","title":{"rendered":"Endace"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Endace?<\/h3>\n<p style=\"margin:0;\"><strong>Endace<\/strong> \u0435 \u043e\u0440\u0430\u043b\u043d\u0430 \u0442\u0430\u0431\u043b\u0435\u0442\u043a\u0430 \u043e\u0442 Cipla, \u0441\u044a\u0434\u044a\u0440\u0436\u0430\u0449\u0430 <strong>megestrol acetate<\/strong> \u0432 <strong>40 mg and 160 mg<\/strong> &mdash; a synthetic progestin used as <strong>appetite stimulant<\/strong> in cancer cachexia and HIV-related anorexia, and as palliative endocrine therapy in advanced hormone-receptor-positive breast cancer and endometrial cancer. Standard appetite-stimulant dose: <strong>400&ndash;800 mg\/day<\/strong> (typically 800 mg\/day in cancer cachexia). Onset of appetite improvement at 1&ndash;2 weeks; weight gain (mostly fat, not muscle) at 4&ndash;6 weeks. <strong>Increased venous thromboembolism risk<\/strong> &mdash; caution in immobilised cancer patients; consider DVT prophylaxis. Other warnings: adrenal suppression with prolonged use (mineralocorticoid effect), hyperglycaemia, fluid retention.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>\u041a\u0430\u043a\u0432\u043e \u043f\u043e\u043b\u0443\u0447\u0430\u0432\u0430\u0442\u0435 \u0441 MedsBase:<\/strong> \u041f\u0440\u043e\u0438\u0437\u0432\u043e\u0434\u0438\u0442\u0435\u043b, \u0441\u0435\u0440\u0442\u0438\u0444\u0438\u0446\u0438\u0440\u0430\u043d \u043e\u0442 WHO-GMP \u00b7 \u0414\u0438\u0441\u043a\u0440\u0435\u0442\u043d\u0430 \u043e\u043f\u0430\u043a\u043e\u0432\u043a\u0430 \u00b7 \u0414\u043e\u0441\u0442\u0430\u0432\u043a\u0430 \u043f\u043e \u0446\u0435\u043b\u0438\u044f \u0441\u0432\u044f\u0442 \u00b7 \u041d\u0430\u0434 1400 \u043f\u043e\u0442\u0432\u044a\u0440\u0434\u0435\u043d\u0438 <a href=\"https:\/\/medsbase.com\/bg\/reviews\/\">\u043e\u0442\u0437\u0438\u0432\u0430 \u043e\u0442 \u043a\u043b\u0438\u0435\u043d\u0442\u0438<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u0412\u0441\u044f\u043a\u0430 \u043f\u043e\u0440\u044a\u0447\u043a\u0430 \u0435 \u043f\u043e\u043a\u0440\u0438\u0442\u0430 \u043e\u0442 \u043d\u0430\u0448\u0430\u0442\u0430 <a href=\"https:\/\/medsbase.com\/bg\/medsbase-re-shipment-assurance-policy\/\"><strong>\u041f\u043e\u043b\u0438\u0442\u0438\u043a\u0430 \u0437\u0430 \u043f\u043e\u0432\u0442\u043e\u0440\u043d\u0430 \u0438\u0437\u043f\u0440\u0430\u0442\u043a\u0430<\/strong><\/a> \u2014 \u0430\u043a\u043e \u0432\u0430\u0448\u0430\u0442\u0430 \u043f\u0440\u0430\u0442\u043a\u0430 \u043d\u0435 \u043f\u0440\u0438\u0441\u0442\u0438\u0433\u043d\u0435 \u0432 \u0440\u0430\u043c\u043a\u0438\u0442\u0435 \u043d\u0430 20 \u0440\u0430\u0431\u043e\u0442\u043d\u0438 \u0434\u043d\u0438, \u043d\u0438\u0435 \u044f \u0438\u0437\u043f\u0440\u0430\u0449\u0430\u043c\u0435 \u043e\u0442\u043d\u043e\u0432\u043e.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:0 0 24px 0;border-radius:4px;font-size:14px;\"><strong>\u26a0 \u041d\u0435\u043e\u0431\u0445\u043e\u0434\u0438\u043c \u0435 \u0441\u043f\u0435\u0446\u0438\u0430\u043b\u0438\u0437\u0438\u0440\u0430\u043d \u043d\u0430\u0434\u0437\u043e\u0440.<\/strong> \u041b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0430\u0442\u0430 \u043f\u0440\u043e\u0442\u0438\u0432 \u0440\u0430\u043a \u0442\u0440\u044f\u0431\u0432\u0430 \u0434\u0430 \u0431\u044a\u0434\u0430\u0442 \u043f\u0440\u0435\u0434\u043f\u0438\u0441\u0430\u043d\u0438 \u043e\u0442 \u043b\u0435\u043a\u0443\u0432\u0430\u0449 \u043e\u043d\u043a\u043e\u043b\u043e\u0433 \u0441 \u043f\u043e\u0442\u0432\u044a\u0440\u0434\u0435\u043d\u0430 \u0434\u0438\u0430\u0433\u043d\u043e\u0437\u0430, \u0431\u0430\u0437\u043e\u0432\u043e \u0441\u0442\u0430\u0434\u0438\u0440\u0430\u043d\u0435 \u0438 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\u0432\u0437\u0430\u0438\u043c\u043e\u0434\u0435\u0439\u0441\u0442\u0432\u0438\u044f.<\/div>\n<div style=\"background:#f4f8fb;border:1px solid #d6e4ec;padding:12px 18px;margin:14px 0;border-radius:4px;font-size:14px;color:#3a5160;text-align:center;\">\n<strong>\ud83d\udd12 \u0428\u0438\u0444\u0440\u043e\u0432\u0430\u043d\u043e \u043f\u043b\u0430\u0449\u0430\u043d\u0435<\/strong> \u00b7 <strong>\ud83d\udcb3 \u0412\u0435\u0440\u0438\u0444\u0438\u0446\u0438\u0440\u0430\u043d \u043f\u0440\u043e\u0446\u0435\u0441\u043e\u0440<\/strong> \u00b7 <strong>\ud83d\ude9a \u0414\u043e\u0441\u0442\u0430\u0432\u043a\u0430 \u043f\u043e \u0446\u0435\u043b\u0438\u044f \u0441\u0432\u044f\u0442<\/strong> \u00b7 <strong>\u2b50 4.9\/5 \u043e\u0442 1,400+ \u043a\u043b\u0438\u0435\u043d\u0442\u0438<\/strong>\n<\/div>\n<h2 class=\"wp-block-heading\">What Is Endace?<\/h2>\n<p>Endace is an oral tablet from Cipla containing <strong>megestrol acetate<\/strong> (40 mg and 160 mg). Megestrol is a synthetic progestin with potent appetite-stimulant effects. The dominant modern use is as supportive care for <strong>cancer cachexia<\/strong> &mdash; the involuntary weight loss that affects most patients with advanced cancer and significantly worsens quality of life and treatment tolerance. It also retains a niche role in palliative endocrine therapy for advanced hormone-receptor-positive breast and endometrial cancer.<\/p>\n<h2 class=\"wp-block-heading\">\u0423\u043f\u043e\u0442\u0440\u0435\u0431\u0430 \u0438 \u043f\u043e\u043a\u0430\u0437\u0430\u043d\u0438\u044f<\/h2>\n<ul>\n<li><strong>Cancer cachexia<\/strong> &mdash; appetite stimulation and weight gain<\/li>\n<li><strong>HIV-related anorexia and weight loss<\/strong> (less commonly used in 2026 with modern ART)<\/li>\n<li><strong>Palliative endocrine therapy in advanced HR+ breast cancer<\/strong> &mdash; later-line after AI and tamoxifen<\/li>\n<li><strong>Advanced endometrial cancer<\/strong> palliation<\/li>\n<li><strong>\u0418\u0437\u0432\u044a\u043d \u043f\u043e\u043a\u0430\u0437\u0430\u043d\u0438\u044f\u0442\u0430:<\/strong> hot flushes in patients who cannot use HRT<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0414\u043e\u0437\u0438\u0440\u0430\u043d\u0435 \u0438 \u043d\u0430\u0447\u0438\u043d \u043d\u0430 \u043f\u0440\u0438\u0435\u043c\u0430\u043d\u0435<\/h2>\n<ul>\n<li><strong>Cancer cachexia \/ HIV anorexia:<\/strong> 400&ndash;800 mg\/day (often 800 mg\/day) of suspension or tablet equivalent<\/li>\n<li><strong>Breast cancer palliation:<\/strong> 160 mg\/day in divided doses<\/li>\n<li><strong>Endometrial cancer palliation:<\/strong> 80&ndash;320 mg\/day in divided doses<\/li>\n<\/ul>\n<ol>\n<li>Take with food to improve absorption and reduce nausea.<\/li>\n<li>Once daily or in divided doses depending on indication.<\/li>\n<li><strong>\u0417\u0430\u0434\u044a\u043b\u0436\u0438\u0442\u0435\u043b\u043d\u043e \u043d\u0430\u0431\u043b\u044e\u0434\u0435\u043d\u0438\u0435:<\/strong> baseline weight, blood glucose (megestrol commonly raises glucose); BP; signs of DVT; symptoms of adrenal suppression. Periodic FBC.<\/li>\n<li>For cachexia, expect appetite improvement at 1&ndash;2 weeks and weight gain at 4&ndash;6 weeks. Most weight gain is fat (not muscle), and adding nutritional support and resistance exercise where possible amplifies benefit.<\/li>\n<li><strong>\u041d\u0435 \u043f\u0440\u0435\u0443\u0441\u0442\u0430\u043d\u043e\u0432\u044f\u0432\u0430\u0439\u0442\u0435 \u0432\u043d\u0435\u0437\u0430\u043f\u043d\u043e<\/strong> after prolonged use &mdash; risk of adrenal crisis from progestin-mediated adrenal suppression. Taper under specialist guidance.<\/li>\n<\/ol>\n<h2 class=\"wp-block-heading\">\u0421\u0442\u0440\u0430\u043d\u0438\u0447\u043d\u0438 \u0435\u0444\u0435\u043a\u0442\u0438<\/h2>\n<p><strong>\u0427\u0435\u0441\u0442\u0438:<\/strong> weight gain (the desired effect in cachexia), increased appetite, fluid retention, hyperglycaemia, breakthrough vaginal bleeding, mood changes, insomnia, sweating, hot flushes (paradoxically, in some patients).<\/p>\n<p><strong>\u0412\u0430\u0436\u043d\u043e:<\/strong><\/p>\n<ul>\n<li><strong>Venous thromboembolism (DVT, PE)<\/strong> &mdash; consider prophylactic anticoagulation in immobilised cancer patients<\/li>\n<li>Adrenal suppression with prolonged high-dose use<\/li>\n<li>New-onset diabetes or worsening glycaemic control<\/li>\n<li>\u0425\u0438\u043f\u0435\u0440\u0442\u043e\u043d\u0438\u044f<\/li>\n<li>Cushingoid features at high doses<\/li>\n<li>Menstrual irregularities<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u041f\u0440\u0435\u0434\u0443\u043f\u0440\u0435\u0436\u0434\u0435\u043d\u0438\u044f<\/h2>\n<ul>\n<li><strong>\u0411\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0441\u0442:<\/strong> contraindicated. Reliable contraception throughout treatment.<\/li>\n<li><strong>\u041a\u044a\u0440\u043c\u0435\u043d\u0435:<\/strong> \u0438\u0437\u0431\u044f\u0433\u0432\u0430\u0439\u0442\u0435.<\/li>\n<li><strong>Active VTE or recent thrombosis:<\/strong> avoid; alternatives include corticosteroids for cachexia (short-term) or omega-3.<\/li>\n<li><strong>\u0414\u0438\u0430\u0431\u0435\u0442:<\/strong> monitor glucose carefully; insulin or hypoglycaemic dose adjustment likely.<\/li>\n<li><strong>Adrenal insufficiency:<\/strong> taper, do not stop abruptly after prolonged use.<\/li>\n<li><strong>Cardiovascular risk factors:<\/strong> caution &mdash; fluid retention, hypertension.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u041b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0435\u043d\u0438 \u0432\u0437\u0430\u0438\u043c\u043e\u0434\u0435\u0439\u0441\u0442\u0432\u0438\u044f<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;\">\u041a\u043e\u043c\u0431\u0438\u043d\u0438\u0440\u0430\u0439\u0442\u0435 \u0441<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;\">\u0415\u0444\u0435\u043a\u0442<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;\">\u041a\u0430\u043a\u0432\u043e \u0434\u0430 \u043f\u0440\u0430\u0432\u0438\u0442\u0435<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Insulin or oral hypoglycaemics<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Megestrol raises blood glucose &mdash; reduced control<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Monitor glucose; adjust diabetic medication.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Warfarin<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Possible INR change<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Monitor INR.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Other progestins, oestrogens<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Stacked progestin \/ VTE effects<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u0418\u0437\u0431\u044f\u0433\u0432\u0430\u0439\u0442\u0435 \u043a\u043e\u043c\u0431\u0438\u043d\u0430\u0446\u0438\u044f\u0442\u0430.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u0418\u043d\u0445\u0438\u0431\u0438\u0442\u043e\u0440\u0438 \u043d\u0430 \u0430\u0440\u043e\u043c\u0430\u0442\u0430\u0437\u0430\u0442\u0430<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Megestrol provides exogenous progestin &mdash; rarely used together; sequence appropriately<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Specialist judgment.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 class=\"wp-block-heading\">\u0421\u044a\u0445\u0440\u0430\u043d\u0435\u043d\u0438\u0435<\/h2>\n<ul>\n<li>\u0421\u0442\u0430\u0439\u043d\u0430 \u0442\u0435\u043c\u043f\u0435\u0440\u0430\u0442\u0443\u0440\u0430, 15\u201325\u00b0C, \u043e\u0440\u0438\u0433\u0438\u043d\u0430\u043b\u043d\u0430 \u0431\u043b\u0438\u0441\u0442\u0435\u0440\u043d\u0430 \u043e\u043f\u0430\u043a\u043e\u0432\u043a\u0430.<\/li>\n<li>Out of reach of children and pets.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0421\u0432\u044a\u0440\u0437\u0430\u043d\u0438 \u0430\u043b\u0442\u0435\u0440\u043d\u0430\u0442\u0438\u0432\u0438 \u0432 MedsBase<\/h2>\n<p>\u0414\u0440\u0443\u0433\u0438 \u043e\u043d\u043a\u043e\u043b\u043e\u0433\u0438\u0447\u043d\u0438 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0430, \u043d\u0430\u043b\u0438\u0447\u043d\u0438 \u0437\u0430\u0435\u0434\u043d\u043e \u0441 \u0442\u043e\u0437\u0438 \u043f\u0440\u043e\u0434\u0443\u043a\u0442:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/bg\/endoxan\/\"><strong>\u0415\u043d\u0434\u043e\u043a\u0441\u0430\u043d (\u0446\u0438\u043a\u043b\u043e\u0444\u043e\u0441\u0444\u0430\u043c\u0438\u0434 50 mg)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/celkeran\/\"><strong>Celkeran (chlorambucil 2 \/ 5 mg)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/temotero\/\"><strong>\u0422\u0435\u043c\u043e\u0442\u0435\u0440\u043e (\u0442\u0435\u043c\u043e\u0437\u043e\u043b\u043e\u043c\u0438\u0434 20\/100 mg)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/temozol-20\/\"><strong>\u0422\u0435\u043c\u043e\u0437\u043e\u043b (\u0442\u0435\u043c\u043e\u0437\u043e\u043b\u043e\u043c\u0438\u0434 20 mg)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/lomoother\/\"><strong>\u041b\u043e\u043c\u043e\u0442\u0435\u0440 (\u043b\u043e\u043c\u0443\u0441\u0442\u0438\u043d 40 mg)<\/strong><\/a><\/li>\n<\/ul>\n<p><a href=\"https:\/\/medsbase.com\/bg\/anti-cancer-medication\/\">\u0420\u0430\u0437\u0433\u043b\u0435\u0434\u0430\u0439\u0442\u0435 \u0432\u0441\u0438\u0447\u043a\u0438 \u0430\u043d\u0442\u0438\u0440\u0430\u043a\u043e\u0432\u0438 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0430 \u2192<\/a><\/p>\n<h2 id=\"faqs\">\u0427\u0435\u0441\u0442\u043e \u0437\u0430\u0434\u0430\u0432\u0430\u043d\u0438 \u0432\u044a\u043f\u0440\u043e\u0441\u0438<\/h2>\n<h3 class=\"wp-block-heading\">When will I notice the appetite-stimulant effect?<\/h3>\n<p>Improved appetite typically starts at <strong>1\u20132 \u0441\u0435\u0434\u043c\u0438\u0446\u0438<\/strong>. Measurable weight gain (mostly fat, with smaller fluid component) at <strong>4\u20136 \u0441\u0435\u0434\u043c\u0438\u0446\u0438<\/strong>. Most weight gain is fat &mdash; megestrol does not significantly increase lean muscle mass. Adding nutritional support and gentle resistance exercise where possible amplifies the benefit.<\/p>\n<h3 class=\"wp-block-heading\">Why is venous thromboembolism a risk?<\/h3>\n<p>Megestrol is a progestin and shares the VTE risk of all hormonal contraceptives + progestins, particularly in cancer patients (who already carry a 5&ndash;10&times; increased baseline VTE risk). Be alert for unilateral leg swelling, sudden chest pain or breathlessness; seek same-day care if these occur. Consider prophylactic anticoagulation in immobilised cancer patients on megestrol.<\/p>\n<h3 class=\"wp-block-heading\">Will Endace raise my blood sugar?<\/h3>\n<p>Yes &mdash; commonly. Megestrol mimics some of the metabolic effects of corticosteroids (impairs insulin action, raises hepatic glucose output). Diabetic patients usually need their hypoglycaemic medication adjusted upward; new-onset diabetes can occur in non-diabetic patients on long-term high-dose megestrol. Monitor capillary glucose weekly initially.<\/p>\n<h3 class=\"wp-block-heading\">Why must I taper rather than stop Endace?<\/h3>\n<p>Long-term high-dose megestrol suppresses the adrenal axis (mineralocorticoid effect on the hypothalamic-pituitary-adrenal axis). Abrupt discontinuation after &gt; 4&ndash;6 weeks of high-dose use risks <strong>adrenal crisis<\/strong> &mdash; nausea, vomiting, hypotension, hypoglycaemia. Taper down over 2&ndash;4 weeks under specialist supervision.<\/p>\n<h3 class=\"wp-block-heading\">Are there alternatives to Endace for cancer cachexia?<\/h3>\n<p>Limited options with strong evidence. <strong>\u041a\u043e\u0440\u0442\u0438\u043a\u043e\u0441\u0442\u0435\u0440\u043e\u0438\u0434\u0438<\/strong> (dexamethasone 4 mg\/day) provide short-term appetite stimulation but have severe long-term toxicity. <strong>Cannabinoids<\/strong> (dronabinol where legal) have modest evidence. <strong>Anamorelin<\/strong> (ghrelin agonist) is approved in Japan and some other markets. <strong>Olanzapine<\/strong> low-dose has emerging supportive evidence. <strong>Nutritional and exercise interventions<\/strong> remain first-line. Discuss with the palliative care team.<\/p>\n<h3 class=\"wp-block-heading\">Can Endace treat my breast cancer?<\/h3>\n<p>Megestrol has a niche role in palliative endocrine therapy for HR+ advanced breast cancer &mdash; usually <strong>later-line after aromatase inhibitor and tamoxifen failure<\/strong>. It is no longer a first or second-line endocrine choice in most modern practice; CDK4\/6 inhibitors + AI \/ fulvestrant have largely replaced it. Specialist oncology decision.<\/p>\n<h3 class=\"wp-block-heading\">Is Endace safe in pregnancy?<\/h3>\n<p>No &mdash; contraindicated. Megestrol is a progestin and may cause fetal masculinisation and other developmental effects. Reliable contraception throughout treatment.<\/p>\n<h3 class=\"wp-block-heading\">Can I drink alcohol on Endace?<\/h3>\n<p>Occasional small amounts are tolerable but heavy drinking compounds the metabolic side effects (hyperglycaemia, hypertension, fluid retention). Discuss with the supportive care team in the context of overall cancer care.<\/p>\n<p><!-- medsbase-why-order --><\/p>\n<h3>\u0417\u0430\u0449\u043e \u0434\u0430 \u043f\u043e\u0440\u044a\u0447\u0432\u0430\u0442\u0435 \u043e\u0442 MedsBase<\/h3>\n<p>\u0412\u0441\u044f\u043a\u0430 \u043f\u0430\u0440\u0442\u0438\u0434\u0430 \u0435 \u0437\u0430\u043a\u0443\u043f\u0435\u043d\u0430 \u043e\u0442 <strong>\u0421\u0417\u041e-GMP \u0441\u0435\u0440\u0442\u0438\u0444\u0438\u0446\u0438\u0440\u0430\u043d \u043f\u0440\u043e\u0438\u0437\u0432\u043e\u0434\u0438\u0442\u0435\u043b<\/strong>. \u041f\u043e\u0440\u044a\u0447\u043a\u0438\u0442\u0435 \u0441\u0435 \u0438\u0437\u043f\u0440\u0430\u0449\u0430\u0442 \u0432 \u043e\u0431\u0438\u043a\u043d\u043e\u0432\u0435\u043d\u0438 \u043e\u043f\u0430\u043a\u043e\u0432\u043a\u0438 \u0431\u0435\u0437 \u043c\u0430\u0440\u043a\u0438\u0440\u043e\u0432\u043a\u0430 \u043e\u0442 \u043d\u0430\u0448\u0438\u0442\u0435 \u043f\u0430\u0440\u0442\u043d\u044c\u043e\u0440\u0438 \u0437\u0430 \u0438\u0437\u043f\u044a\u043b\u043d\u0435\u043d\u0438\u0435 \u0438 \u0441\u0430 \u043f\u043e\u043a\u0440\u0438\u0442\u0438 \u043e\u0442 \u043d\u0430\u0448\u0430\u0442\u0430 <a href=\"\/bg\/medsbase-re-shipment-assurance-policy\/\">\u041f\u043e\u043b\u0438\u0442\u0438\u043a\u0430 \u0437\u0430 \u043f\u043e\u0432\u0442\u043e\u0440\u043d\u0430 \u0438\u0437\u043f\u0440\u0430\u0442\u043a\u0430<\/a>: \u0430\u043a\u043e \u043f\u0440\u0430\u0442\u043a\u0430\u0442\u0430 \u043d\u0435 \u043f\u0440\u0438\u0441\u0442\u0438\u0433\u043d\u0435 \u0432 \u0440\u0430\u043c\u043a\u0438\u0442\u0435 \u043d\u0430 20 \u0440\u0430\u0431\u043e\u0442\u043d\u0438 \u0434\u043d\u0438, \u0438\u0437\u043f\u0440\u0430\u0449\u0430\u043c\u0435 \u0431\u0435\u0437\u043f\u043b\u0430\u0442\u043d\u0430 \u043f\u043e\u0432\u0442\u043e\u0440\u043d\u0430 \u043f\u0440\u0430\u0442\u043a\u0430, \u0431\u0435\u0437 \u0434\u043e\u043f\u044a\u043b\u043d\u0438\u0442\u0435\u043b\u043d\u0438 \u0432\u044a\u043f\u0440\u043e\u0441\u0438.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">\u0421\u0432\u044a\u0440\u0437\u0430\u043d\u0438 \u043f\u0440\u043e\u0442\u0438\u0432\u043e\u0440\u0430\u043a\u043e\u0432\u0438 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0430<\/h3>\n<p>\u0414\u0440\u0443\u0433\u0438 \u043e\u043d\u043a\u043e\u043b\u043e\u0433\u0438\u0447\u043d\u0438 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0430, \u043d\u0430\u043b\u0438\u0447\u043d\u0438 \u0437\u0430\u0435\u0434\u043d\u043e \u0441 \u0442\u043e\u0437\u0438 \u043f\u0440\u043e\u0434\u0443\u043a\u0442:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/bg\/cytomid\/\">Cytomid (flutamide 250 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/bicalumutide\/\">\u0411\u0438\u043a\u0430\u043b\u0443\u043c\u0438\u0442\u0438\u0434 (\u0431\u0438\u043a\u0430\u043b\u0443\u0442\u0430\u043c\u0438\u0434 50 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/bdenza\/\">\u0411\u0434\u0435\u043d\u0437\u0430 (\u0435\u043d\u0437\u0430\u043b\u0443\u0442\u0430\u043c\u0438\u0434 40 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/tamilong\/\">Tamilong (\u0442\u0430\u043c\u043e\u043a\u0441\u0438\u0444\u0435\u043d 10\/20 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/xtane\/\">Xtane (\u0435\u043a\u0437\u0435\u043c\u0435\u0441\u0442\u0430\u043d 25 mg)<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Manages appetite loss<br \/>\n\u2705 Treats breast cancer<br \/>\n\u2705 \u041a\u043e\u043d\u0442\u0440\u043e\u043b\u0438\u0440\u0430 \u0435\u043d\u0434\u043e\u043c\u0435\u0442\u0440\u0438\u0430\u043b\u043d\u0438\u044f \u0440\u0430\u043a<br \/>\n\u2705 Aids weight gain<br \/>\n\u2705 \u041f\u043e\u0434\u043e\u0431\u0440\u044f\u0432\u0430 \u043a\u0430\u0447\u0435\u0441\u0442\u0432\u043e\u0442\u043e \u043d\u0430 \u0436\u0438\u0432\u043e\u0442\u0430<\/p>\n<p>Endace contains Megestrol Acetate.<\/p>","protected":false},"featured_media":58732,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3595,3141,3223],"product_tag":[4556,4557],"class_list":{"0":"post-58731","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-cancer-medication","7":"product_cat-category-overview","8":"product_cat-chronic-conditions","9":"product_tag-endace","10":"product_tag-megestrol","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product\/58731","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/comments?post=58731"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/media\/58732"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/media?parent=58731"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product_brand?post=58731"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product_cat?post=58731"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product_tag?post=58731"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}