{"id":60195,"date":"2024-02-28T06:37:55","date_gmt":"2024-02-28T06:37:55","guid":{"rendered":"https:\/\/medsname.com\/prazinec\/"},"modified":"2026-05-09T11:38:18","modified_gmt":"2026-05-09T11:38:18","slug":"prazinec","status":"publish","type":"product","link":"https:\/\/medsbase.com\/bg\/product\/prazinec\/","title":{"rendered":"Prazinec"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"margin:0 0 22px;padding:16px 20px;background:#fff8e1;border-left:4px solid #f5a623;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px;font-size:18px;color:#2c3e50;\">Quick Answer &mdash; What is Prazinec?<\/h3>\n<div style=\"margin:0;font-size:15px;line-height:1.55;color:#333;\">\n<p><strong>Prazinec<\/strong> \u0435 <strong>praziquantel 600&nbsp;mg<\/strong> \u043e\u0442 <strong>Sun Pharma<\/strong>. Praziquantel is the WHO Essential Medicine for <strong>schistosomiasis, intestinal flukes, liver flukes, and most cestodes including neurocysticercosis<\/strong>. Standard adult dose for schistosomiasis: <strong>40&nbsp;mg\/kg as a single dose<\/strong>; for tapeworm: 5&ndash;10&nbsp;mg\/kg single dose; for neurocysticercosis: 50&nbsp;mg\/kg\/day in 3 divided doses for 14&ndash;30 days under specialist supervision.<\/p>\n<\/div>\n<\/div>\n<p style=\"font-size:14px;margin:12px 0;\">\ud83d\udcd6 <strong>Full guide:<\/strong> <a href=\"\/bg\/ivermectin-complete-guide\/\">Buy Ivermectin for Humans Online &#8212; Dosage, Safety &amp; What to Know<\/a><\/p>\n<div class=\"medsbase-trust-strip\" style=\"margin:24px 0;padding:14px 18px;background:#f4f4f4;border:1px solid #e1e1e1;border-radius:4px;font-size:14px;color:#444;line-height:1.55;\"><strong>\u0417\u0430\u0449\u043e \u0434\u0430 \u043f\u043e\u0440\u044a\u0447\u0432\u0430\u0442\u0435 \u043e\u0442 MedsBase:<\/strong> \u2713 \u0414\u043e\u0441\u0442\u0430\u0432\u0435\u043d \u043e\u0442 <strong>WHO-GMP \u0441\u0435\u0440\u0442\u0438\u0444\u0438\u0446\u0438\u0440\u0430\u043d\u0438 \u043f\u0440\u043e\u0438\u0437\u0432\u043e\u0434\u0438\u0442\u0435\u043b\u0438<\/strong> \u00b7 \u2713 \u0414\u0438\u0441\u043a\u0440\u0435\u0442\u043d\u0430 \u043e\u043f\u0430\u043a\u043e\u0432\u043a\u0430 \u00b7 \u2713 \u0414\u043e\u0441\u0442\u0430\u0432\u043a\u0430 \u043f\u043e \u0446\u0435\u043b\u0438\u044f \u0441\u0432\u044f\u0442 \u00b7 \u2713 <strong>1,400+ \u043f\u043e\u0442\u0440\u0435\u0431\u0438\u0442\u0435\u043b\u0441\u043a\u0438 \u0440\u0435\u0432\u044e\u0442\u0430<\/strong> \u0432 <a href=\"https:\/\/medsbase.com\/bg\/reviews\/\">medsbase.com\/reviews<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u0412\u0441\u044f\u043a\u0430 \u043f\u043e\u0440\u044a\u0447\u043a\u0430 \u0435 \u043f\u043e\u043a\u0440\u0438\u0442\u0430 \u043e\u0442 \u043d\u0430\u0448\u0430\u0442\u0430 <a href=\"https:\/\/medsbase.com\/bg\/medsbase-re-shipment-assurance-policy\/\"><strong>\u041f\u043e\u043b\u0438\u0442\u0438\u043a\u0430 \u0437\u0430 \u043f\u043e\u0432\u0442\u043e\u0440\u043d\u0430 \u0438\u0437\u043f\u0440\u0430\u0442\u043a\u0430<\/strong><\/a> \u2014 \u0430\u043a\u043e \u0432\u0430\u0448\u0430\u0442\u0430 \u043f\u0440\u0430\u0442\u043a\u0430 \u043d\u0435 \u043f\u0440\u0438\u0441\u0442\u0438\u0433\u043d\u0435 \u0432 \u0440\u0430\u043c\u043a\u0438\u0442\u0435 \u043d\u0430 20 \u0440\u0430\u0431\u043e\u0442\u043d\u0438 \u0434\u043d\u0438, \u043d\u0438\u0435 \u044f \u0438\u0437\u043f\u0440\u0430\u0449\u0430\u043c\u0435 \u043e\u0442\u043d\u043e\u0432\u043e.<\/p>\n<h3>\u0417\u0430\u0449\u043e \u0434\u0430 \u043f\u043e\u0440\u044a\u0447\u0432\u0430\u0442\u0435 \u043e\u0442 MedsBase<\/h3>\n<p>\u041d\u0430\u0448\u0438\u0442\u0435 \u0433\u0435\u043d\u0435\u0440\u0438\u0447\u043d\u0438 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0430 \u0441\u0435 \u0434\u043e\u0441\u0442\u0430\u0432\u044f\u0442 \u043e\u0442 \u043f\u0440\u043e\u0438\u0437\u0432\u043e\u0434\u0438\u0442\u0435\u043b\u0438, \u0441\u0435\u0440\u0442\u0438\u0444\u0438\u0446\u0438\u0440\u0430\u043d\u0438 \u043e\u0442 WHO-GMP, \u0438 \u0441\u0435 \u0438\u0437\u043f\u0440\u0430\u0449\u0430\u0442 \u043f\u043e \u0446\u0435\u043b\u0438\u044f \u0441\u0432\u044f\u0442 \u0432 \u0434\u0438\u0441\u043a\u0440\u0435\u0442\u043d\u0430, \u043e\u0431\u0438\u043a\u043d\u043e\u0432\u0435\u043d\u0430 \u043e\u043f\u0430\u043a\u043e\u0432\u043a\u0430 \u2014 \u0431\u0435\u0437 \u0438\u043c\u0435 \u043d\u0430 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u043e\u0442\u043e \u0432\u044a\u043d\u0448\u043d\u043e \u043d\u0430 \u043f\u0440\u0430\u0442\u043a\u0430\u0442\u0430. \u041f\u043b\u0430\u0449\u0430\u043d\u0438\u044f\u0442\u0430 \u0441 \u043a\u0430\u0440\u0442\u0430 \u0441\u0435 \u043e\u0431\u0440\u0430\u0431\u043e\u0442\u0432\u0430\u0442 \u0447\u0440\u0435\u0437 \u0440\u0435\u0433\u0443\u043b\u0438\u0440\u0430\u043d \u043f\u0440\u043e\u0446\u0435\u0441\u043e\u0440 (\u043e\u043f\u0438\u0441\u0430\u043d\u0438\u0435\u0442\u043e \u043d\u0430 \u0438\u0437\u0432\u043b\u0435\u0447\u0435\u043d\u0438\u0435\u0442\u043e \u0432\u043a\u043b\u044e\u0447\u0432\u0430 \u0440\u0435\u0433\u0443\u043b\u0438\u0440\u0430\u043d \u043f\u0440\u043e\u0446\u0435\u0441\u043e\u0440 \u0437\u0430 \u043f\u043b\u0430\u0449\u0430\u043d\u0435 \u0441 \u043a\u0430\u0440\u0442\u0430 \u2014 \u043d\u0438\u043a\u043e\u0433\u0430 \u201cMedsBase\u201d \u0438\u043b\u0438 \u0438\u043c\u0435 \u043d\u0430 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u043e). \u041f\u0440\u0438\u0435\u043c\u0430\u0442 \u0441\u0435 \u0441\u044a\u0449\u043e \u043a\u0440\u0438\u043f\u0442\u043e\u0432\u0430\u043b\u0443\u0442\u0438 \u0438 \u0431\u0430\u043d\u043a\u043e\u0432 \u043f\u0440\u0435\u0432\u043e\u0434 SEPA. \u0412\u0441\u044f\u043a\u0430 \u043f\u043e\u0440\u044a\u0447\u043a\u0430 \u0435 \u043f\u043e\u0434\u043a\u0440\u0435\u043f\u0435\u043d\u0430 \u043e\u0442 \u043d\u0430\u0448\u0430\u0442\u0430 \u043f\u043e\u043b\u0438\u0442\u0438\u043a\u0430 \u0437\u0430 \u0433\u0430\u0440\u0430\u043d\u0442\u0438\u0440\u0430\u043d\u043e \u043f\u0440\u0435\u0438\u0437\u043f\u0440\u0430\u0449\u0430\u043d\u0435.<\/p>\n<h2 class=\"wp-block-heading\">What is Prazinec?<\/h2>\n<p><strong>Prazinec<\/strong> is praziquantel 600&nbsp;mg from <strong>Sun Pharma<\/strong>. Praziquantel is one of the most important drugs in tropical medicine &mdash; the global standard for schistosomiasis (which affects roughly 240 million people worldwide), and the agent of choice for most cestode and trematode infections. WHO mass-drug-administration programmes have used praziquantel to treat over a billion people since the 1990s.<\/p>\n<h2 class=\"wp-block-heading\">\u041c\u0435\u0445\u0430\u043d\u0438\u0437\u044a\u043c \u043d\u0430 \u0434\u0435\u0439\u0441\u0442\u0432\u0438\u0435<\/h2>\n<p>Praziquantel <strong>increases calcium permeability<\/strong> across the parasite tegument (outer covering), causing rapid sustained muscle contraction. This paralyses the worm and exposes its surface antigens to host immune attack &mdash; a one-two punch of pharmacological paralysis followed by immune-mediated killing. The mechanism explains why praziquantel works so well in immunocompetent patients and is somewhat less effective in heavily immunosuppressed hosts.<\/p>\n<p>Oral bioavailability is good (~80%) but first-pass hepatic metabolism is heavy &mdash; only about 25% reaches systemic circulation as active drug. Plasma half-life is 1&ndash;1.5 hours.<\/p>\n<h2 class=\"wp-block-heading\">Prazinec indications and dose<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;font-size:14px;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">\u041f\u043e\u043a\u0430\u0437\u0430\u043d\u0438\u0435<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">\u0414\u043e\u0437\u0430<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">\u0413\u0440\u0430\u0444\u0438\u043a<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Schistosomiasis (S. mansoni, S. haematobium, S. japonicum)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">40&nbsp;mg\/kg<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Single dose (S. japonicum: 60&nbsp;mg\/kg)<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Intestinal tapeworm (Taenia saginata, T. solium)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">5&ndash;10&nbsp;mg\/kg<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">\u0415\u0434\u043d\u043e\u043a\u0440\u0430\u0442\u043d\u0430 \u0434\u043e\u0437\u0430<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Hymenolepis nana<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">25&nbsp;mg\/kg<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Single dose, repeat at 1 week<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Liver flukes (Clonorchis, Opisthorchis)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">25&nbsp;mg\/kg TID<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">For 1 day (75&nbsp;mg\/kg total)<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Lung fluke (Paragonimus)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">25&nbsp;mg\/kg TID<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">For 2 days<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Neurocysticercosis (specialist)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">50&nbsp;mg\/kg\/day in 3 doses<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">For 14&ndash;30 days WITH steroid cover<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Take with water or a soft drink during or shortly after a meal. Tablets have a bitter taste &mdash; do not chew. Children &gt; 4 years: same weight-based dosing applies.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;line-height:1.55;color:#444;\"><strong>Neurocysticercosis is a specialist diagnosis.<\/strong> Praziquantel for CNS cysticercosis must be given with concurrent corticosteroid (typically dexamethasone) to suppress the inflammatory response to dying cysts &mdash; otherwise raised intracranial pressure can be catastrophic. Imaging (MRI brain) is mandatory before treatment. Do not self-treat suspected neurocysticercosis.<\/div>\n<h2 class=\"wp-block-heading\">\u0421\u0442\u0440\u0430\u043d\u0438\u0447\u043d\u0438 \u0435\u0444\u0435\u043a\u0442\u0438<\/h2>\n<ul>\n<li><strong>\u0427\u0435\u0441\u0442\u0438:<\/strong> abdominal discomfort, nausea, malaise, headache, dizziness, drowsiness &mdash; usually within first 24&nbsp;hours, often related to dying parasites rather than the drug<\/li>\n<li><strong>\u041f\u043e-\u0440\u044f\u0434\u043a\u043e:<\/strong> urticaria, fever, transient eosinophilia rebound<\/li>\n<li><strong>\u0420\u044f\u0434\u043a\u043e:<\/strong> bradycardia, transient transaminase rise<\/li>\n<li><strong>Neurocysticercosis-specific:<\/strong> headache, seizures, raised intracranial pressure as cysts die &mdash; the reason for steroid cover<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0412\u0437\u0430\u0438\u043c\u043e\u0434\u0435\u0439\u0441\u0442\u0432\u0438\u044f \u0441 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0430<\/h2>\n<ul>\n<li><strong>\u0421\u0438\u043b\u043d\u0438 CYP3A4 \u0438\u043d\u0434\u0443\u043a\u0442\u043e\u0440\u0438<\/strong> (rifampicin, carbamazepine, phenytoin, phenobarbital) &mdash; reduce praziquantel levels significantly; avoid combination or use alternative<\/li>\n<li><strong>\u0421\u0438\u043b\u043d\u0438 CYP3A4 \u0438\u043d\u0445\u0438\u0431\u0438\u0442\u043e\u0440\u0438<\/strong> (ketoconazole, ritonavir, cimetidine) &mdash; raise levels; reduce dose if combination unavoidable<\/li>\n<li><strong>Dexamethasone<\/strong> &mdash; reduces praziquantel levels by ~50%, but the combination is still required for neurocysticercosis (clinical effect retained)<\/li>\n<li><strong>Chloroquine<\/strong> &mdash; reduces praziquantel levels modestly<\/li>\n<li><strong>Grapefruit juice<\/strong> &mdash; raises levels; avoid during treatment<\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;line-height:1.55;color:#444;\"><strong>\u0411\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0441\u0442 \u0438 \u043a\u044a\u0440\u043c\u0435\u043d\u0435.<\/strong> \u0410\u043b\u0431\u0435\u043d\u0434\u0430\u0437\u043e\u043b \u0438 \u043c\u0435\u0431\u0435\u043d\u0434\u0430\u0437\u043e\u043b \u041d\u0415 \u0441\u0435 \u043f\u0440\u0435\u043f\u043e\u0440\u044a\u0447\u0432\u0430\u0442 \u043f\u0440\u0435\u0437 \u043f\u044a\u0440\u0432\u0438\u044f \u0442\u0440\u0438\u043c\u0435\u0441\u0442\u044a\u0440 (\u0434\u0430\u043d\u043d\u0438 \u0437\u0430 \u0442\u0435\u0440\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u043e\u0441\u0442 \u043f\u0440\u0438 \u0436\u0438\u0432\u043e\u0442\u043d\u0438). \u0423\u043f\u043e\u0442\u0440\u0435\u0431\u0430\u0442\u0430 \u0435 \u043f\u0440\u0438\u0435\u043c\u043b\u0438\u0432\u0430 \u043f\u0440\u0435\u0437 \u0432\u0442\u043e\u0440\u0438\u044f\/\u0442\u0440\u0435\u0442\u0438\u044f \u0442\u0440\u0438\u043c\u0435\u0441\u0442\u044a\u0440 \u043f\u0440\u0438 \u0443\u043c\u0435\u0440\u0435\u043d\u0430 \u0434\u043e \u0442\u0435\u0436\u043a\u0430 \u0438\u043d\u0432\u0430\u0437\u0438\u044f \u0441 \u0447\u0435\u0440\u0432\u0435\u0438. \u0414\u0430\u043d\u043d\u0438\u0442\u0435 \u0437\u0430 \u0443\u043f\u043e\u0442\u0440\u0435\u0431\u0430\u0442\u0430 \u043d\u0430 \u0438\u0432\u0435\u0440\u043c\u0435\u043a\u0442\u0438\u043d \u043f\u043e \u0432\u0440\u0435\u043c\u0435 \u043d\u0430 \u0431\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0441\u0442 \u0441\u0430 \u043e\u0433\u0440\u0430\u043d\u0438\u0447\u0435\u043d\u0438, \u043d\u043e \u0441\u0430 \u043e\u0431\u043d\u0430\u0434\u0435\u0436\u0434\u0430\u0432\u0430\u0449\u0438 \u0432 \u043f\u0440\u043e\u0433\u0440\u0430\u043c\u0438\u0442\u0435 \u0437\u0430 \u043c\u0430\u0441\u043e\u0432\u043e \u043b\u0435\u0447\u0435\u043d\u0438\u0435 \u043d\u0430 \u0421\u0417\u041e; \u0438\u0437\u0431\u044f\u0433\u0432\u0430\u0439\u0442\u0435 \u043f\u0440\u0435\u0437 \u043f\u044a\u0440\u0432\u0438\u044f \u0442\u0440\u0438\u043c\u0435\u0441\u0442\u044a\u0440, \u043a\u044a\u0434\u0435\u0442\u043e \u0438\u043c\u0430 \u0430\u043b\u0442\u0435\u0440\u043d\u0430\u0442\u0438\u0432\u0438. \u041f\u0440\u0430\u0437\u0438\u043a\u0432\u0430\u043d\u0442\u0435\u043b \u0438 \u043f\u0438\u0440\u0430\u043d\u0442\u0435\u043b \u0441\u0430 \u0441\u044a\u0432\u043c\u0435\u0441\u0442\u0438\u043c\u0438 \u0441 \u0431\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0441\u0442.<\/div>\n<h2 class=\"wp-block-heading\">\u041f\u0440\u043e\u0442\u0438\u0432\u043e\u043f\u043e\u043a\u0430\u0437\u0430\u043d\u0438\u044f<\/h2>\n<ul>\n<li>Hypersensitivity to praziquantel<\/li>\n<li>Ocular cysticercosis &mdash; treatment can destroy the eye; specialist surgical assessment first<\/li>\n<li>Children &lt; 4 years &mdash; safety not established<\/li>\n<li>\u0422\u0435\u0436\u043a\u043e \u0447\u0435\u0440\u043d\u043e\u0434\u0440\u043e\u0431\u043d\u043e \u0443\u0432\u0440\u0435\u0436\u0434\u0430\u043d\u0435<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0421\u044a\u0445\u0440\u0430\u043d\u0435\u043d\u0438\u0435<\/h2>\n<p>Store Prazinec below 30&deg;C in the original blister, protect from light and moisture.<\/p>\n<h3 class=\"wp-block-heading\">\u0417\u0430\u0449\u043e \u0434\u0430 \u043f\u043e\u0440\u044a\u0447\u0432\u0430\u0442\u0435 \u043e\u0442 MedsBase<\/h3>\n<p>Prazinec is supplied from a <strong>\u0421\u0417\u041e-GMP \u0441\u0435\u0440\u0442\u0438\u0444\u0438\u0446\u0438\u0440\u0430\u043d \u043f\u0440\u043e\u0438\u0437\u0432\u043e\u0434\u0438\u0442\u0435\u043b<\/strong>, \u043e\u043f\u0430\u043a\u043e\u0432\u0430\u043d\u043e \u0434\u0438\u0441\u043a\u0440\u0435\u0442\u043d\u043e \u0438 \u0438\u0437\u043f\u0440\u0430\u0442\u0435\u043d\u043e \u043f\u043e \u0446\u0435\u043b\u0438\u044f \u0441\u0432\u044f\u0442. \u0412\u0441\u044f\u043a\u0430 \u043f\u043e\u0440\u044a\u0447\u043a\u0430 \u0435 \u043f\u043e\u043a\u0440\u0438\u0442\u0430 \u043e\u0442 \u043d\u0430\u0448\u0430\u0442\u0430 <a href=\"https:\/\/medsbase.com\/bg\/medsbase-re-shipment-assurance-policy\/\">\u041f\u043e\u043b\u0438\u0442\u0438\u043a\u0430 \u0437\u0430 \u043f\u043e\u0432\u0442\u043e\u0440\u043d\u0430 \u0438\u0437\u043f\u0440\u0430\u0442\u043a\u0430<\/a> \u2014 \u043d\u0438\u043a\u043e\u0433\u0430 \u043d\u0435 \u043d\u043e\u0441\u0438\u0442\u0435 \u0440\u0430\u0437\u0445\u043e\u0434\u0438\u0442\u0435 \u0437\u0430 \u0438\u0437\u0433\u0443\u0431\u0435\u043d\u0430 \u043f\u0440\u0430\u0442\u043a\u0430.<\/p>\n<h2 id=\"faqs\">\u0427\u0435\u0441\u0442\u043e \u0437\u0430\u0434\u0430\u0432\u0430\u043d\u0438 \u0432\u044a\u043f\u0440\u043e\u0441\u0438<\/h2>\n<h3 class=\"wp-block-heading\">How quickly does Prazinec work?<\/h3>\n<p>Schistosomes and most flukes are paralysed within hours. Egg shedding stops over the following 1&ndash;2 weeks. For schistosomiasis, urine or stool testing at 4&ndash;6 weeks confirms cure.<\/p>\n<h3 class=\"wp-block-heading\">Why take Prazinec with food?<\/h3>\n<p>Food increases bioavailability roughly 2-fold. For most indications this is helpful. Do not chew &mdash; the bitter taste is intense.<\/p>\n<h3 class=\"wp-block-heading\">Will I see worms in my stool after?<\/h3>\n<p>For tapeworm, expect partial passage of fragmented proglottids over the days following the dose &mdash; the worm is partly digested by host enzymes after praziquantel has done its job. For schistosomiasis the eggs are microscopic; you won&rsquo;t see worms.<\/p>\n<h3 class=\"wp-block-heading\">Is Prazinec safe in pregnancy?<\/h3>\n<p>WHO endorses praziquantel use in pregnancy where infection is symptomatic or the worm burden is significant. The first trimester is preferred to be avoided where alternatives exist. Consult a clinician for individualised guidance.<\/p>\n<h3 class=\"wp-block-heading\">Can children take Prazinec?<\/h3>\n<p>Yes from age 4 with the same weight-based dosing as adults. WHO mass-drug-administration programmes routinely treat school-age children for schistosomiasis with single-dose praziquantel.<\/p>\n<h3 class=\"wp-block-heading\">What if I have neurocysticercosis?<\/h3>\n<p>Treatment requires neurology supervision. MRI imaging, concurrent dexamethasone, and (for ocular involvement) ophthalmology assessment are mandatory. Self-treatment can be catastrophic &mdash; the brain inflammation from dying cysts can cause raised intracranial pressure.<\/p>\n<h3 class=\"wp-block-heading\">Does praziquantel treat ascaris or pinworm?<\/h3>\n<p>No. Praziquantel covers cestodes (tapeworms) and trematodes (flukes including schistosoma). For nematodes (ascaris, pinworm, hookworm, whipworm) use albendazole or mebendazole.<\/p>\n<h3 class=\"wp-block-heading\">Can I drink alcohol after the dose?<\/h3>\n<p>Avoid alcohol on the day of treatment &mdash; it amplifies the dizziness and drowsiness common in the first 24&nbsp;hours.<\/p>\n<h3 class=\"wp-block-heading\">Why might Prazinec fail?<\/h3>\n<p>Most common reasons: under-dosing (especially in heavy patients), reinfection from continued exposure (re-entering schistosomiasis-endemic water bodies), or co-administration with strong CYP3A4 inducers (rifampicin, anticonvulsants) that reduce drug levels.<\/p>\n<h3 class=\"wp-block-heading\">Should I retest after treatment?<\/h3>\n<p>For schistosomiasis, retest with urine or stool at 4&ndash;6 weeks. For intestinal tapeworm, retest at 1 and 3 months. For neurocysticercosis, repeat MRI at 3&ndash;6 months under specialist guidance.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">\u0414\u0440\u0443\u0433\u0438 \u0430\u043d\u0442\u0438\u043f\u0430\u0440\u0430\u0437\u0438\u0442\u043d\u0438 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0430<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/bg\/niclosig\/\">Niclosig (niclosamide 500 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/prazinec\/\">Prazinec (praziquantel 600 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/abd-400-albendazole\/\">ABD 400 (\u0430\u043b\u0431\u0435\u043d\u0434\u0430\u0437\u043e\u043b 400 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/mebex\/\">Mebex (mebendazole)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/tinvista\/\">Tinvista (tinidazole)<\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:22px 0;border-radius:4px;font-size:14px;color:#444;\"><strong>\u041c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0430 \u0434\u0435\u043a\u043b\u0430\u0440\u0430\u0446\u0438\u044f.<\/strong> \u0422\u0430\u0437\u0438 \u0441\u0442\u0440\u0430\u043d\u0438\u0446\u0430 \u0435 \u0441\u0430\u043c\u043e \u0437\u0430 \u043e\u0431\u0440\u0430\u0437\u043e\u0432\u0430\u0442\u0435\u043b\u043d\u0438 \u0446\u0435\u043b\u0438 \u0438 \u043d\u0435 \u0437\u0430\u043c\u0435\u0441\u0442\u0432\u0430 \u043f\u0440\u043e\u0444\u0435\u0441\u0438\u043e\u043d\u0430\u043b\u0435\u043d \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438 \u0441\u044a\u0432\u0435\u0442. \u041a\u043e\u043d\u0441\u0443\u043b\u0442\u0438\u0440\u0430\u0439\u0442\u0435 \u0441\u0435 \u0441 \u043a\u0432\u0430\u043b\u0438\u0444\u0438\u0446\u0438\u0440\u0430\u043d \u043b\u0435\u043a\u0430\u0440 \u043f\u0440\u0435\u0434\u0438 \u0434\u0430 \u0437\u0430\u043f\u043e\u0447\u043d\u0435\u0442\u0435 \u043f\u0440\u0438\u0435\u043c \u043d\u0430 \u0430\u043d\u0442\u0438\u0445\u0435\u043b\u043c\u0438\u043d\u0442\u0438\u043a, \u043e\u0441\u043e\u0431\u0435\u043d\u043e \u0430\u043a\u043e \u0441\u0442\u0435 \u0431\u0440\u0435\u043c\u0435\u043d\u043d\u0438 \u0438\u043b\u0438 \u043a\u044a\u0440\u043c\u0438\u0442\u0435, \u0441 \u0438\u043c\u0443\u043d\u043e\u0441\u0443\u043f\u0440\u0435\u0441\u0438\u044f, \u043b\u0435\u043a\u0443\u0432\u0430\u0442\u0435 \u0434\u0435\u0442\u0435 \u043f\u043e\u0434 2 \u0433\u043e\u0434\u0438\u043d\u0438 \u0438\u043b\u0438 \u0430\u043a\u043e \u0441\u0438\u043c\u043f\u0442\u043e\u043c\u0438\u0442\u0435 \u043f\u0440\u043e\u0434\u044a\u043b\u0436\u0430\u0432\u0430\u0442 \u0441\u043b\u0435\u0434 \u043a\u0443\u0440\u0441\u0430 \u043d\u0430 \u043b\u0435\u0447\u0435\u043d\u0438\u0435. \u0415\u043e\u0437\u0438\u043d\u043e\u0444\u0438\u043b\u0438\u044f, \u0437\u0430\u0433\u0443\u0431\u0430 \u043d\u0430 \u0442\u0435\u0433\u043b\u043e, \u043f\u043e\u0441\u0442\u043e\u044f\u043d\u043d\u0430 \u0431\u043e\u043b\u043a\u0430 \u0432 \u043a\u043e\u0440\u0435\u043c\u0430 \u0438\u043b\u0438 \u0441\u0438\u043c\u043f\u0442\u043e\u043c\u0438, \u0441\u0432\u044a\u0440\u0437\u0430\u043d\u0438 \u0441 \u043f\u044a\u0442\u0443\u0432\u0430\u043d\u0435, \u0438\u0437\u0438\u0441\u043a\u0432\u0430\u0442 \u043a\u043b\u0438\u043d\u0438\u0447\u043d\u0430 \u043e\u0446\u0435\u043d\u043a\u0430. \u0422\u0435\u0436\u043a\u0438 \u043f\u0430\u0440\u0430\u0437\u0438\u0442\u043d\u0438 \u0437\u0430\u0431\u043e\u043b\u044f\u0432\u0430\u043d\u0438\u044f (\u043d\u0435\u0432\u0440\u043e\u0446\u0438\u0441\u0442\u0438\u0446\u0435\u0440\u043a\u043e\u0437\u0430, \u0445\u0438\u043f\u0435\u0440\u0438\u043d\u0444\u0435\u043a\u0446\u0438\u044f \u0441 Strongyloides, \u0448\u0438\u0441\u0442\u043e\u0437\u043e\u043c\u0438\u0430\u0437\u0430 \u0441 \u0443\u0432\u0440\u0435\u0436\u0434\u0430\u043d\u0435 \u043d\u0430 \u043e\u0440\u0433\u0430\u043d\u0438) \u0441\u0435 \u043b\u0435\u043a\u0443\u0432\u0430\u0442 \u043e\u0442 \u0441\u043f\u0435\u0446\u0438\u0430\u043b\u0438\u0441\u0442.<\/div>","protected":false},"excerpt":{"rendered":"<p>Prazinec (praziquantel 600 mg, Sun Pharma) \u2014 WHO essential medicine for schistosomiasis, intestinal and liver flukes, and most cestodes. Standard 40 mg\/kg single dose for schistosomiasis.<\/p>","protected":false},"featured_media":60196,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3342,3856],"product_tag":[4819,4596],"class_list":{"0":"post-60195","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-general-health","8":"product_cat-threadworm-treatment","9":"product_tag-prazinec","10":"product_tag-praziquantel","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product\/60195","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/comments?post=60195"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/media\/60196"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/media?parent=60195"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product_brand?post=60195"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product_cat?post=60195"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product_tag?post=60195"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}