{"id":60451,"date":"2024-02-28T06:49:25","date_gmt":"2024-02-28T06:49:25","guid":{"rendered":"https:\/\/medsname.com\/xarelto-20\/"},"modified":"2026-05-01T10:49:16","modified_gmt":"2026-05-01T10:49:16","slug":"xarelto-20","status":"publish","type":"product","link":"https:\/\/medsbase.com\/bg\/product\/xarelto-20\/","title":{"rendered":"Xarelto 20"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Xarelto 20?<\/h3>\n<p style=\"margin:0;\"><strong>Xarelto 20<\/strong> is 20 mg rivaroxaban tablets from Bayer &mdash; direct oral anticoagulant (DOAC) &mdash; direct factor Xa inhibitor. Rivaroxaban was introduced by Bayer in 2008 as <strong>\u041a\u0441\u0430\u0440\u0435\u043b\u0442\u043e<\/strong> &mdash; the first oral direct factor Xa inhibitor. ROCKET-AF (2011) and EINSTEIN-DVT\/PE (2010) established non-inferiority to warfarin in AF and VTE. directly inhibits factor Xa, the central convergence point of intrinsic and extrinsic coagulation cascades, reducing thrombin generation. 5-13 hour half-life; renally and hepatically cleared. Dosing: <strong>Non-valvular AF:<\/strong> 20 mg once daily with food (15 mg if CrCl 15-50 mL\/min). <strong>DVT\/PE treatment:<\/strong> 15 mg twice daily for 3 weeks then 20 mg once daily. <strong>COMPASS vascular prophylaxis:<\/strong> 2.5 mg twice daily with aspirin 75-100 mg daily. Major bleeding ~3-5%\/year in AF; GI bleeding somewhat higher than warfarin. No routine monitoring unlike warfarin &mdash; a major practical advantage. Reversal with andexanet alfa (specific antidote) where available, or 4-factor prothrombin complex concentrate. Anticoagulant and antiplatelet selection is individualised to diagnosis, bleeding risk, renal function, and drug interactions. Specialist or family-physician supervision is standard.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>\u041a\u0430\u043a\u0432\u043e \u043f\u043e\u043b\u0443\u0447\u0430\u0432\u0430\u0442\u0435 \u0441 MedsBase:<\/strong> \u041f\u0440\u043e\u0438\u0437\u0432\u043e\u0434\u0438\u0442\u0435\u043b, \u0441\u0435\u0440\u0442\u0438\u0444\u0438\u0446\u0438\u0440\u0430\u043d \u043e\u0442 WHO-GMP \u00b7 \u0414\u0438\u0441\u043a\u0440\u0435\u0442\u043d\u0430 \u043e\u043f\u0430\u043a\u043e\u0432\u043a\u0430 \u00b7 \u0414\u043e\u0441\u0442\u0430\u0432\u043a\u0430 \u043f\u043e \u0446\u0435\u043b\u0438\u044f \u0441\u0432\u044f\u0442 \u00b7 \u041d\u0430\u0434 1400 \u043f\u043e\u0442\u0432\u044a\u0440\u0434\u0435\u043d\u0438 <a href=\"https:\/\/medsbase.com\/bg\/reviews\/\">\u043e\u0442\u0437\u0438\u0432\u0430 \u043e\u0442 \u043a\u043b\u0438\u0435\u043d\u0442\u0438<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u0412\u0441\u044f\u043a\u0430 \u043f\u043e\u0440\u044a\u0447\u043a\u0430 \u0435 \u043f\u043e\u043a\u0440\u0438\u0442\u0430 \u043e\u0442 \u043d\u0430\u0448\u0430\u0442\u0430 <a href=\"https:\/\/medsbase.com\/bg\/medsbase-re-shipment-assurance-policy\/\"><strong>\u041f\u043e\u043b\u0438\u0442\u0438\u043a\u0430 \u0437\u0430 \u043f\u043e\u0432\u0442\u043e\u0440\u043d\u0430 \u0438\u0437\u043f\u0440\u0430\u0442\u043a\u0430<\/strong><\/a> \u2014 \u0430\u043a\u043e \u0432\u0430\u0448\u0430\u0442\u0430 \u043f\u0440\u0430\u0442\u043a\u0430 \u043d\u0435 \u043f\u0440\u0438\u0441\u0442\u0438\u0433\u043d\u0435 \u0432 \u0440\u0430\u043c\u043a\u0438\u0442\u0435 \u043d\u0430 20 \u0440\u0430\u0431\u043e\u0442\u043d\u0438 \u0434\u043d\u0438, \u043d\u0438\u0435 \u044f \u0438\u0437\u043f\u0440\u0430\u0449\u0430\u043c\u0435 \u043e\u0442\u043d\u043e\u0432\u043e.<\/p>\n<h3>\u0417\u0430\u0449\u043e \u0434\u0430 \u043f\u043e\u0440\u044a\u0447\u0432\u0430\u0442\u0435 \u043e\u0442 MedsBase<\/h3>\n<p>\u041d\u0430\u0448\u0438\u0442\u0435 \u0433\u0435\u043d\u0435\u0440\u0438\u0447\u043d\u0438 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0430 \u0441\u0435 \u0434\u043e\u0441\u0442\u0430\u0432\u044f\u0442 \u043e\u0442 \u043f\u0440\u043e\u0438\u0437\u0432\u043e\u0434\u0438\u0442\u0435\u043b\u0438, \u0441\u0435\u0440\u0442\u0438\u0444\u0438\u0446\u0438\u0440\u0430\u043d\u0438 \u043e\u0442 WHO-GMP, \u0438 \u0441\u0435 \u0438\u0437\u043f\u0440\u0430\u0449\u0430\u0442 \u043f\u043e \u0446\u0435\u043b\u0438\u044f \u0441\u0432\u044f\u0442 \u0432 \u0434\u0438\u0441\u043a\u0440\u0435\u0442\u043d\u0430, \u043e\u0431\u0438\u043a\u043d\u043e\u0432\u0435\u043d\u0430 \u043e\u043f\u0430\u043a\u043e\u0432\u043a\u0430 \u2014 \u0431\u0435\u0437 \u0438\u043c\u0435 \u043d\u0430 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u043e\u0442\u043e \u0432\u044a\u043d\u0448\u043d\u043e \u043d\u0430 \u043f\u0440\u0430\u0442\u043a\u0430\u0442\u0430. \u041f\u043b\u0430\u0449\u0430\u043d\u0438\u044f\u0442\u0430 \u0441 \u043a\u0430\u0440\u0442\u0430 \u0441\u0435 \u043e\u0431\u0440\u0430\u0431\u043e\u0442\u0432\u0430\u0442 \u0447\u0440\u0435\u0437 \u0440\u0435\u0433\u0443\u043b\u0438\u0440\u0430\u043d \u043f\u0440\u043e\u0446\u0435\u0441\u043e\u0440 (\u043e\u043f\u0438\u0441\u0430\u043d\u0438\u0435\u0442\u043e \u043d\u0430 \u0438\u0437\u0432\u043b\u0435\u0447\u0435\u043d\u0438\u0435\u0442\u043e \u0432\u043a\u043b\u044e\u0447\u0432\u0430 \u0440\u0435\u0433\u0443\u043b\u0438\u0440\u0430\u043d \u043f\u0440\u043e\u0446\u0435\u0441\u043e\u0440 \u0437\u0430 \u043f\u043b\u0430\u0449\u0430\u043d\u0435 \u0441 \u043a\u0430\u0440\u0442\u0430 \u2014 \u043d\u0438\u043a\u043e\u0433\u0430 \u201cMedsBase\u201d \u0438\u043b\u0438 \u0438\u043c\u0435 \u043d\u0430 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u043e). \u041f\u0440\u0438\u0435\u043c\u0430\u0442 \u0441\u0435 \u0441\u044a\u0449\u043e \u043a\u0440\u0438\u043f\u0442\u043e\u0432\u0430\u043b\u0443\u0442\u0438 \u0438 \u0431\u0430\u043d\u043a\u043e\u0432 \u043f\u0440\u0435\u0432\u043e\u0434 SEPA. \u0412\u0441\u044f\u043a\u0430 \u043f\u043e\u0440\u044a\u0447\u043a\u0430 \u0435 \u043f\u043e\u0434\u043a\u0440\u0435\u043f\u0435\u043d\u0430 \u043e\u0442 \u043d\u0430\u0448\u0430\u0442\u0430 \u043f\u043e\u043b\u0438\u0442\u0438\u043a\u0430 \u0437\u0430 \u0433\u0430\u0440\u0430\u043d\u0442\u0438\u0440\u0430\u043d\u043e \u043f\u0440\u0435\u0438\u0437\u043f\u0440\u0430\u0449\u0430\u043d\u0435.<\/p>\n<h2 class=\"wp-block-heading\">What Is Xarelto 20?<\/h2>\n<p>Xarelto 20 is 20 mg rivaroxaban tablets from Bayer, supplied in 14-112 tablets. Rivaroxaban was introduced by Bayer in 2008 as <strong>\u041a\u0441\u0430\u0440\u0435\u043b\u0442\u043e<\/strong> &mdash; the first oral direct factor Xa inhibitor. ROCKET-AF (2011) and EINSTEIN-DVT\/PE (2010) established non-inferiority to warfarin in AF and VTE.<\/p>\n<h2 class=\"wp-block-heading\">How Rivaroxaban Works<\/h2>\n<p>Rivaroxaban directly inhibits factor Xa, the central convergence point of intrinsic and extrinsic coagulation cascades, reducing thrombin generation. 5-13 hour half-life; renally and hepatically cleared.<\/p>\n<h2 class=\"wp-block-heading\">\u041e\u0434\u043e\u0431\u0440\u0435\u043d\u0438 \u0443\u043f\u043e\u0442\u0440\u0435\u0431\u0438<\/h2>\n<ul>\n<li><strong>\u041d\u0435\u043a\u043b\u0430\u043f\u0430\u043d\u043d\u0430 \u0430\u0442\u0440\u0438\u0430\u043b\u043d\u0430 \u0444\u0438\u0431\u0440\u0438\u043b\u0430\u0446\u0438\u044f<\/strong> &mdash; stroke prevention (ROCKET-AF)<\/li>\n<li><strong>Deep vein thrombosis and pulmonary embolism<\/strong> &mdash; treatment (EINSTEIN trials) and extended prophylaxis<\/li>\n<li><strong>VTE prophylaxis<\/strong> after major orthopaedic surgery<\/li>\n<li><strong>Stable coronary or peripheral arterial disease<\/strong> &mdash; 2.5 mg twice daily + aspirin (COMPASS 2017) for atherothrombotic prevention in high-risk patients<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0414\u043e\u0437\u0438\u0440\u0430\u043d\u0435<\/h2>\n<p><strong>Non-valvular AF:<\/strong> 20 mg once daily with food (15 mg if CrCl 15-50 mL\/min). <strong>DVT\/PE treatment:<\/strong> 15 mg twice daily for 3 weeks then 20 mg once daily. <strong>COMPASS vascular prophylaxis:<\/strong> 2.5 mg twice daily with aspirin 75-100 mg daily.<\/p>\n<h2 class=\"wp-block-heading\">\u0420\u0438\u0441\u043a \u043e\u0442 \u043a\u0440\u044a\u0432\u043e\u0442\u0435\u0447\u0435\u043d\u0438\u0435 \u0438 \u043c\u043e\u043d\u0438\u0442\u043e\u0440\u0438\u043d\u0433<\/h2>\n<p>Major bleeding ~3-5%\/year in AF; GI bleeding somewhat higher than warfarin. No routine monitoring unlike warfarin &mdash; a major practical advantage. Reversal with andexanet alfa (specific antidote) where available, or 4-factor prothrombin complex concentrate.<\/p>\n<p><strong>No routine blood monitoring required<\/strong> &mdash; a major practical advantage over warfarin. Check renal function at baseline, 3 months, then annually (or sooner in acute illness or 75+ years). No dietary restrictions. Missed doses: take if within 6 hours of scheduled dose; otherwise skip &mdash; do not double up.<\/p>\n<h2 class=\"wp-block-heading\">\u0421\u0442\u0440\u0430\u043d\u0438\u0447\u043d\u0438 \u0435\u0444\u0435\u043a\u0442\u0438<\/h2>\n<ul>\n<li>Major bleeding (~3-5%\/year in AF)<\/li>\n<li>GI bleeding (higher than apixaban, slightly higher than warfarin)<\/li>\n<li>\u0410\u043d\u0435\u043c\u0438\u044f<\/li>\n<li>Minor bleeding (epistaxis, bruising)<\/li>\n<li>\u0425\u0435\u043f\u0430\u0442\u043e\u0442\u043e\u043a\u0441\u0438\u0447\u043d\u043e\u0441\u0442 (\u0440\u044f\u0434\u043a\u043e)<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u041f\u0440\u043e\u0442\u0438\u0432\u043e\u043f\u043e\u043a\u0430\u0437\u0430\u043d\u0438\u044f<\/h2>\n<ul>\n<li>\u0410\u043a\u0442\u0438\u0432\u043d\u043e \u043f\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u0447\u043d\u043e \u043a\u044a\u0440\u0432\u0435\u043d\u0435<\/li>\n<li>Severe renal impairment (CrCl &lt;15 mL\/min)<\/li>\n<li>\u0422\u0435\u0436\u043a\u043e \u0443\u0432\u0440\u0435\u0436\u0434\u0430\u043d\u0435 \u043d\u0430 \u0447\u0435\u0440\u043d\u0438\u044f \u0434\u0440\u043e\u0431 (Child-Pugh B \u0438\u043b\u0438 C)<\/li>\n<li>Mechanical heart valve (use warfarin)<\/li>\n<li>Moderate-to-severe mitral stenosis<\/li>\n<li>Pregnancy (crosses placenta; use heparin \/ warfarin)<\/li>\n<li>Concurrent strong dual inhibitors of CYP3A4 + P-gp (azole antifungals, HIV protease inhibitors)<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u041b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0435\u043d\u0438 \u0432\u0437\u0430\u0438\u043c\u043e\u0434\u0435\u0439\u0441\u0442\u0432\u0438\u044f<\/h2>\n<ul>\n<li><strong>Strong CYP3A4 + P-gp dual inhibitors &mdash; CRITICAL.<\/strong> Azole antifungals (ketoconazole, itraconazole), HIV protease inhibitors, clarithromycin &mdash; substantially raise rivaroxaban levels; contraindicated.<\/li>\n<li><strong>\u0421\u0438\u043b\u043d\u0438 \u0438\u043d\u0434\u0443\u0446\u0438\u0440\u0430\u0449\u0438 \u0432\u0435\u0449\u0435\u0441\u0442\u0432\u0430 \u043d\u0430 CYP3A4 + P-gp<\/strong> (rifampicin, phenytoin, carbamazepine, St John&#8217;s Wort) &mdash; lower levels; avoid or monitor closely.<\/li>\n<li><strong>Other anticoagulants, heparins<\/strong> &mdash; do not combine except in specific bridging situations under specialist supervision.<\/li>\n<li><strong>NSAIDs, antiplatelets<\/strong> &mdash; additive bleeding risk.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0421\u044a\u0445\u0440\u0430\u043d\u0435\u043d\u0438\u0435<\/h2>\n<p>Store Xarelto 20 below 25&deg;C. Keep out of reach of children.<\/p>\n<h2 id=\"faqs\">\u0427\u0435\u0441\u0442\u043e \u0437\u0430\u0434\u0430\u0432\u0430\u043d\u0438 \u0432\u044a\u043f\u0440\u043e\u0441\u0438<\/h2>\n<h3 class=\"wp-block-heading\">Do I need blood tests on Xarelto 20?<\/h3>\n<p>No routine blood tests for efficacy. Check renal function annually.<\/p>\n<h3 class=\"wp-block-heading\">What should I do if I cut myself while on Xarelto 20?<\/h3>\n<p>\u041f\u0440\u0438\u043b\u043e\u0436\u0435\u0442\u0435 \u0441\u0442\u0430\u0431\u0438\u043b\u0435\u043d \u0434\u0438\u0440\u0435\u043a\u0442\u0435\u043d \u043d\u0430\u0442\u0438\u0441\u043a \u0437\u0430 15-20 \u043c\u0438\u043d\u0443\u0442\u0438 \u0431\u0435\u0437 \u0434\u0430 \u043f\u0440\u043e\u0432\u0435\u0440\u044f\u0432\u0430\u0442\u0435. \u041f\u043e\u0432\u0435\u0447\u0435\u0442\u043e \u043c\u0430\u043b\u043a\u0438 \u043f\u043e\u0440\u044f\u0437\u0432\u0430\u043d\u0438\u044f \u0441\u043f\u0438\u0440\u0430\u0442 \u043d\u043e\u0440\u043c\u0430\u043b\u043d\u043e; \u043f\u0440\u043e\u0434\u044a\u043b\u0436\u0438\u0442\u0435\u043b\u043d\u043e \u043a\u044a\u0440\u0432\u0435\u043d\u0435 \u043d\u0430\u0434 20 \u043c\u0438\u043d\u0443\u0442\u0438 \u0438\u043b\u0438 \u043a\u044a\u0440\u0432\u0435\u043d\u0435 \u043f\u0440\u0435\u0437 \u043d\u044f\u043a\u043e\u043b\u043a\u043e \u043f\u0440\u0435\u0432\u0440\u044a\u0437\u043a\u0438 \u0438\u0437\u0438\u0441\u043a\u0432\u0430 \u0441\u043f\u0435\u0448\u043d\u0430 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0430 \u043f\u0440\u0435\u0433\u043b\u0435\u0434. \u0421\u044a\u043e\u0431\u0449\u0435\u0442\u0435 \u0437\u0430 \u0432\u0441\u044f\u043a\u0430 \u0447\u0435\u0440\u043d\u0430 \u0438\u043b\u0438 \u043a\u044a\u0440\u0432\u0430\u0432\u0430 \u0438\u0437\u043f\u0440\u0430\u0436\u043d\u0435\u043d\u0438\u044f, \u044f\u0440\u043a\u043e\u0447\u0435\u0440\u0432\u0435\u043d\u043e \u0440\u0435\u043a\u0442\u0430\u043b\u043d\u043e \u043a\u044a\u0440\u0432\u0435\u043d\u0435, \u0445\u0435\u043c\u0430\u0442\u0443\u0440\u0438\u044f, \u043d\u0435\u043e\u0431\u044f\u0441\u043d\u0438\u043c\u0438 \u043d\u0430\u0442\u044a\u0440\u0442\u0432\u0430\u043d\u0438\u044f, \u043d\u043e\u0441\u043e\u0432\u0438 \u043a\u044a\u0440\u0432\u0435\u043d\u0438\u044f \u043d\u0430\u0434 15 \u043c\u0438\u043d\u0443\u0442\u0438 \u0438\u043b\u0438 \u043c\u0435\u043d\u0441\u0442\u0440\u0443\u0430\u043b\u043d\u043e \u043a\u044a\u0440\u0432\u0435\u043d\u0435, \u0437\u043d\u0430\u0447\u0438\u0442\u0435\u043b\u043d\u043e \u043f\u043e-\u043e\u0431\u0438\u043b\u043d\u043e \u043e\u0442 \u043e\u0431\u0438\u0447\u0430\u0439\u043d\u043e\u0442\u043e.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Xarelto 20 in pregnancy?<\/h3>\n<p>No &mdash; crosses placenta; DOACs are contraindicated in pregnancy. Use LMWH.<\/p>\n<h3 class=\"wp-block-heading\">\u0410\u043c\u0438 \u0430\u043a\u043e \u0441\u0435 \u043d\u0430\u043b\u043e\u0436\u0438 \u043e\u043f\u0435\u0440\u0430\u0446\u0438\u044f?<\/h3>\n<p>Inform the surgical team well in advance. Rivaroxaban stopped 24-48 hours before surgery depending on bleeding risk and renal function.<\/p>\n<h3 class=\"wp-block-heading\">Where can I buy Xarelto 20 online?<\/h3>\n<p>You can buy Xarelto 20 (rivaroxaban 20 mg, 14-112 tablets) from MedsBase with discreet packaging and worldwide shipping.<\/p>\n<h2 class=\"wp-block-heading\">\u0421\u0432\u044a\u0440\u0437\u0430\u043d\u0438 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0430 \u0437\u0430 \u0441\u044a\u0440\u0434\u0435\u0447\u043d\u043e-\u0441\u044a\u0434\u043e\u0432\u0430\u0442\u0430 \u0441\u0438\u0441\u0442\u0435\u043c\u0430<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/bg\/aldactone\/\">\u0410\u043b\u0434\u0430\u043a\u0442\u043e\u043d \u2014 \u0421\u043f\u0438\u0440\u043e\u043d\u043e\u043b\u0430\u043a\u0442\u043e\u043d<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/cordarone\/\">Cordarone \u2014 Amiodarone 100\/200 mg<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/ivabrad\/\">Ivabrad \u2014 \u0418\u0432\u0430\u0431\u0440\u0430\u0434\u0438\u043d 7.5 mg<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/lonitab\/\">Lonitab \u2014 \u041c\u0438\u043d\u043e\u043a\u0441\u0438\u0434\u0438\u043b 5 mg (\u043e\u0440\u0430\u043b\u0435\u043d \u0432\u0430\u0437\u043e\u0434\u0438\u043b\u0430\u0442\u0430\u0442\u043e\u0440)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/rioci-1\/\">Rioci 1 \u2014 Riociguat 1 mg (\u0441\u0442\u0438\u043c\u0443\u043b\u0430\u0442\u043e\u0440 \u043d\u0430 sGC \u0437\u0430 PAH)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/vymada\/\">Vymada \u2014 \u0421\u0430\u043a\u0443\u0431\u0438\u0442\u0440\u0438\u043b\/\u0412\u0430\u043b\u0441\u0430\u0440\u0442\u0430\u043d ARNI<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/high-blood-pressure-medication\/\"><strong>\u0420\u0430\u0437\u0433\u043b\u0435\u0434\u0430\u0439\u0442\u0435 \u0432\u0441\u0438\u0447\u043a\u0438 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0430 \u0437\u0430 \u0432\u0438\u0441\u043e\u043a\u043e \u043a\u0440\u044a\u0432\u043d\u043e \u043d\u0430\u043b\u044f\u0433\u0430\u043d\u0435<\/strong><\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:24px 0;border-radius:4px;\"><strong>\u2695 \u041c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u043e \u0438\u0437\u0432\u0435\u0441\u0442\u0438\u0435.<\/strong> \u0422\u0430\u0437\u0438 \u0441\u0442\u0440\u0430\u043d\u0438\u0446\u0430 \u0435 \u0441\u0430\u043c\u043e \u0437\u0430 \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u043e\u043d\u043d\u0438 \u0446\u0435\u043b\u0438 \u0438 \u043d\u0435 \u0437\u0430\u043c\u0435\u0441\u0442\u0432\u0430 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0442\u0435 \u0441\u044a\u0432\u0435\u0442\u0438 \u043d\u0430 \u043a\u0432\u0430\u043b\u0438\u0444\u0438\u0446\u0438\u0440\u0430\u043d \u0437\u0434\u0440\u0430\u0432\u0435\u043d \u0441\u043f\u0435\u0446\u0438\u0430\u043b\u0438\u0441\u0442. \u0425\u0438\u043f\u0435\u0440\u0442\u043e\u043d\u0438\u044f\u0442\u0430, \u0441\u044a\u0440\u0434\u0435\u0447\u043d\u0430\u0442\u0430 \u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u044a\u0447\u043d\u043e\u0441\u0442 \u0438 \u0430\u0440\u0438\u0442\u043c\u0438\u0438\u0442\u0435 \u0438\u0437\u0438\u0441\u043a\u0432\u0430\u0442 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0430, \u043c\u043e\u043d\u0438\u0442\u043e\u0440\u0438\u043d\u0433 \u0438 \u0438\u043d\u0434\u0438\u0432\u0438\u0434\u0443\u0430\u043b\u0438\u0437\u0438\u0440\u0430\u043d\u0435 \u043d\u0430 \u0434\u043e\u0437\u0430\u0442\u0430 \u043e\u0442 \u043b\u0435\u043a\u0430\u0440 \u2014 \u0432\u0438\u043d\u0430\u0433\u0438 \u0438\u0437\u043f\u043e\u043b\u0437\u0432\u0430\u0439\u0442\u0435 \u0431\u0435\u0442\u0430-\u0431\u043b\u043e\u043a\u0430\u0442\u043e\u0440\u0438 \u043f\u043e\u0434 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u043e \u0440\u044a\u043a\u043e\u0432\u043e\u0434\u0441\u0442\u0432\u043e.<\/div>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">\u0421\u0432\u044a\u0440\u0437\u0430\u043d\u0438 \u0430\u043b\u0442\u0435\u0440\u043d\u0430\u0442\u0438\u0432\u0438<\/h3>\n<p>\u0414\u0440\u0443\u0433\u0438 \u043f\u0440\u043e\u0434\u0443\u043a\u0442\u0438 \u0432 <strong>\u0425\u0440\u043e\u043d\u0438\u0447\u043d\u0438 \u0437\u0430\u0431\u043e\u043b\u044f\u0432\u0430\u043d\u0438\u044f<\/strong> \u043a\u043e\u0438\u0442\u043e \u043a\u043b\u0438\u0435\u043d\u0442\u0438\u0442\u0435 \u0441\u044a\u0449\u043e \u0440\u0430\u0437\u0433\u043b\u0435\u0436\u0434\u0430\u0442:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/bg\/ivrea-shampoo\/\">Ivrea Shampoo<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/rosu-hdl\/\">Rosu-HDL<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/tiova-rotacaps\/\">Tiova Rotacaps<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/glynase-xl\/\">Glynase Xl<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/bg\/trajenta-duo\/\">\u0422\u0440\u0430\u0434\u0436\u0435\u043d\u0442\u0430 \u0414\u0443\u043e<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>Xarelto 20 is Bayer&#8217;s rivaroxaban 20 mg tablets \u2014 the first oral direct factor Xa inhibitor. ROCKET-AF (2011) non-inferior to warfarin in non-valvular AF; EINSTEIN-DVT\/PE (2010) established single-drug treatment for VTE. COMPASS (2017) showed 2.5 mg twice daily + aspirin reduced CV events in stable CAD\/PAD. No routine blood monitoring needed (vs warfarin INR). Contraindicated in mechanical valves, pregnancy, severe CKD. Andexanet alfa reverses in emergencies.<\/p>","protected":false},"featured_media":60452,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3635,3141,3223,3342,3260,3356],"product_tag":[4863,4864],"class_list":{"0":"post-60451","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-coagulants","7":"product_cat-category-overview","8":"product_cat-chronic-conditions","9":"product_cat-general-health","10":"product_cat-heart-blood-pressure","11":"product_cat-high-blood-pressure-medication","12":"product_tag-rivaroxaban","13":"product_tag-xarelto","15":"first","16":"instock","17":"shipping-taxable","18":"purchasable","19":"product-type-variable","20":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product\/60451","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/comments?post=60451"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/media\/60452"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/media?parent=60451"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product_brand?post=60451"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product_cat?post=60451"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/bg\/wp-json\/wp\/v2\/product_tag?post=60451"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}