{"id":51251,"date":"2023-09-20T09:19:19","date_gmt":"2023-09-20T09:19:19","guid":{"rendered":"https:\/\/medsname.com\/dorzox-eye-drop\/"},"modified":"2026-04-30T10:25:30","modified_gmt":"2026-04-30T10:25:30","slug":"dorzox-eye-drop","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/dorzox-eye-drop\/","title":{"rendered":"Dorzox Eye Drop"},"content":{"rendered":"

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\u26a1 Rychl\u00e1 odpov\u011b\u010f \u2014 Co jsou Dorzox o\u010dn\u00ed kapky?<\/h3>\n

Dorzox o\u010dn\u00ed kapky obsahuj\u00ed Dorzolamid HCl 2%, co\u017e je inhibitor karboanhydr\u00e1zy (CAI) ve form\u011b o\u010dn\u00edch kapek, kter\u00fd sni\u017euje nitroo\u010dn\u00ed tlak o 18\u201322 % sn\u00ed\u017een\u00edm tvorby komorov\u00e9 vody. Aplikuje se t\u0159ikr\u00e1t denn\u011b jako monoterapie nebo dvakr\u00e1t denn\u011b jako dopl\u0148kov\u00e1 l\u00e9\u010dba. Nevhodn\u00e9 pro pacienty se z\u00e1va\u017enou alergi\u00ed na sulfonamidy.<\/p>\n<\/div>\n

Pro\u010d objedn\u00e1vat z MedsBase?<\/strong> Dod\u00e1v\u00e1no od v\u00fdrobce certifikovan\u00e9ho WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Doprava po cel\u00e9m sv\u011bt\u011b \u00b7 1 400+ ov\u011b\u0159en\u00fdch recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a><\/div>\n

\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n

Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n

Dorzox o\u010dn\u00ed kapky jsou dod\u00e1v\u00e1ny od v\u00fdrobce certifikovan\u00e9ho WHO-GMP a expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v nen\u00e1padn\u00e9m obalu. Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/a> \u2014 pokud nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me bez dal\u0161\u00edch n\u00e1klad\u016f. Podpo\u0159eno v\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdmi recenzemi z\u00e1kazn\u00edk\u016f.<\/p>\n

Co jsou Dorzox o\u010dn\u00ed kapky?<\/h2>\n

Dorzox o\u010dn\u00ed kapky vyr\u00e1b\u00ed spole\u010dnost Cipla a obsahuj\u00ed Dorzolamid HCl 2% jako steriln\u00ed \u010dir\u00fd o\u010dn\u00ed roztok. Jde o lok\u00e1ln\u00ed inhibitor karboanhydr\u00e1zy pou\u017e\u00edvan\u00fd ke sn\u00ed\u017een\u00ed nitroo\u010dn\u00edho tlaku u glaukomu. Dorzolamid je \u010dir\u00fd roztok. N\u011bkte\u0159\u00ed pacienti uv\u00e1d\u011bj\u00ed p\u0159echodnou ho\u0159kou chu\u0165 zp\u016fsobenou odtokem do krku a m\u00edrn\u00e9 \u0161t\u00edp\u00e1n\u00ed zp\u016fsoben\u00e9 kysel\u00fdm pH (pH 5,6).<\/p>\n

Jak to funguje<\/h2>\n

Dorzolamid HCl blokuje izoenzym karboanhydr\u00e1zy II v \u0159asnat\u00e9m epitelu, \u010d\u00edm\u017e zpomaluje tvorbu hydrogenuhli\u010ditanu a n\u00e1sledn\u00fd tok sod\u00edku a vody do zadn\u00ed komory o\u010dn\u00ed. V\u00fdsledkem je sn\u00ed\u017een\u00e1 tvorba komorov\u00e9 vody a ni\u017e\u0161\u00ed nitroo\u010dn\u00ed tlak. Lok\u00e1ln\u00ed CAI dosahuj\u00ed v\u00fdznamn\u00e9 nitroo\u010dn\u00ed koncentrace bez syst\u00e9mov\u00fdch vedlej\u0161\u00edch \u00fa\u010dink\u016f peror\u00e1ln\u00edho acetazolamidu (parestezie, ledvinov\u00e9 kameny, poruchy chuti).<\/p>\n

Indikace & D\u00e1vkov\u00e1n\u00ed<\/h2>\n\n\n\n\n\n\n\n\n
Indikace<\/th>\nD\u00e1vka<\/th>\n<\/tr>\n<\/thead>\n
Monoterapie<\/td>\n1 kapka do posti\u017een\u00e9ho oka t\u0159ikr\u00e1t denn\u011b<\/td>\n<\/tr>\n
Dopl\u0148kov\u00e1 l\u00e9\u010dba k beta-blok\u00e1toru nebo PGA<\/td>\n1 kapka dvakr\u00e1t denn\u011b<\/td>\n<\/tr>\n
Pokud suspenze<\/td>\nNepou\u017eiteln\u00e9 \u2014 dorzolamid je \u010dir\u00fd roztok<\/td>\n<\/tr>\n
V\u00edce kapek<\/td>\nPo\u010dkejte 5 minut mezi r\u016fzn\u00fdmi p\u0159\u00edpravky<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Vedlej\u0161\u00ed \u00fa\u010dinky<\/h2>\n

Lok\u00e1ln\u00ed:<\/strong> rozmazan\u00e9 vid\u011bn\u00ed (m\u00e9n\u011b \u010dast\u00e9), \u0161t\u00edp\u00e1n\u00ed p\u0159i aplikaci (\u010dast\u00e9, zejm\u00e9na u dorzolamidu), ho\u0159k\u00e1 chu\u0165 v \u00fastech (odtok nosolakrim\u00e1ln\u00edm kan\u00e1lem), konjunktiv\u00e1ln\u00ed hyper\u00e9mie, o\u010dn\u00ed sv\u011bd\u011bn\u00ed, reakce o\u010dn\u00edch v\u00ed\u010dek.<\/p>\n

Syst\u00e9mov\u00e9:<\/strong> bolest hlavy, \u00fanava (vz\u00e1cn\u00e9), ledvinov\u00e9 kameny (velmi vz\u00e1cn\u00e9 p\u0159i topick\u00e9m pou\u017eit\u00ed, na rozd\u00edl od peror\u00e1ln\u00edho acetazolamidu).<\/p>\n

Varov\u00e1n\u00ed p\u0159ed zk\u0159\u00ed\u017eenou reaktivitou se sulfonamidy.<\/strong> Jak brinzolamid, tak dorzolamid jsou deriv\u00e1ty sulfonamidu. U pacient\u016f se z\u00e1va\u017enou alergi\u00ed na sulfonamidy (Stevens-Johnson\u016fv syndrom, anafylaxe na sulfamethoxazol) se vz\u00e1cn\u011b vyvinuly zk\u0159\u00ed\u017een\u00e9 reakce. Anamn\u00e9za m\u00edrn\u00e9 vyr\u00e1\u017eky po sulfonamidech nen\u00ed absolutn\u00ed kontraindikac\u00ed, ale proberte to se sv\u00fdm l\u00e9ka\u0159em. V\u011bt\u0161ina reakc\u00ed je m\u00edrn\u00e9 konjunktiv\u00e1ln\u00ed podr\u00e1\u017ed\u011bn\u00ed sp\u00ed\u0161e ne\u017e syst\u00e9mov\u00e1 p\u0159ecitliv\u011blost.<\/div>\n

Varov\u00e1n\u00ed a kontraindikace<\/h2>\n