{"id":51397,"date":"2023-09-20T09:21:06","date_gmt":"2023-09-20T09:21:06","guid":{"rendered":"https:\/\/medsname.com\/zuflo-ofloxacin-eye-drop\/"},"modified":"2026-04-30T10:25:27","modified_gmt":"2026-04-30T10:25:27","slug":"zuflo-ofloxacin-eye-drop","status":"publish","type":"product","link":"https:\/\/medsbase.com\/zuflo-ofloxacin-eye-drop\/","title":{"rendered":"Zuflo Ofloxacin Eye Drop"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"background:#fffbe6;border-left:4px solid #f5a623;padding:14px 18px;margin:14px 0 22px;border-radius:6px;font-size:15px;line-height:1.55;\">\n<h3 style=\"margin:0 0 6px;font-size:17px;color:#8a6d3b;\">\u26a1 Quick Answer \u2014 What is Zuflo Eye Drop?<\/h3>\n<p style=\"margin:0;\">Zuflo Eye Drop is Ofloxacin 0.3%, a 2nd-generation fluoroquinolone antibiotic eye drop for bacterial conjunctivitis, blepharitis, and corneal ulcers. Used 4\u20136 times daily for 5\u20137 days. Best reserved for confirmed bacterial infection \u2014 most acute conjunctivitis is viral or self-limiting.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f6f7fb;border:1px solid #e3e5ee;border-radius:8px;padding:14px 18px;margin:18px 0;font-size:14px;line-height:1.55;\"><strong style=\"color:#1f3661;\">Why order from MedsBase?<\/strong> Sourced from a WHO-GMP certified manufacturer \u00b7 Discreet packaging \u00b7 Worldwide Shipping \u00b7 <a href=\"\/reviews\/\" rel=\"noopener\">1,400+ verified customer reviews<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Every order is covered by our <a href=\"https:\/\/medsbase.com\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 if your parcel does not arrive within 20 business days, we reship it.<\/p>\n<h3>Why order from MedsBase<\/h3>\n<p>Zuflo Eye Drop is sourced from a WHO-GMP certified manufacturer and shipped worldwide in plain, discreet packaging. Every order is covered by our <a href=\"\/medsbase-re-shipment-assurance-policy\/\" rel=\"noopener\">Reshipment Assurance Policy<\/a> \u2014 if it has not arrived after 20 business days we reship at no extra cost. Backed by 1,400+ verified customer reviews.<\/p>\n<h2>What is Zuflo Eye Drop?<\/h2>\n<p>Zuflo Eye Drop is manufactured by FDC and contains Ofloxacin 0.3% as a sterile ophthalmic solution. It is a 2nd-generation fluoroquinolone antibiotic used for bacterial eye infections.<\/p>\n<h2>How It Works<\/h2>\n<p>Ofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, the enzymes responsible for unwinding and re-coiling bacterial DNA. Without these enzymes the bacterium cannot replicate or repair DNA damage, leading to bacterial cell death. Because the eye has no equivalent enzymes, host cells are unaffected at therapeutic concentrations.<\/p>\n<h2>Indications<\/h2>\n<ul>\n<li><strong>Bacterial conjunctivitis<\/strong> \u2014 confirmed or strongly suspected (purulent discharge, mattered lashes on waking, no concurrent upper-respiratory symptoms)<\/li>\n<li><strong>Bacterial blepharitis<\/strong> \u2014 when conservative lid hygiene fails<\/li>\n<li><strong>Bacterial corneal ulcer \/ keratitis<\/strong> \u2014 under ophthalmologist supervision; intensive hourly dosing required<\/li>\n<li><strong>Pre-\/post-operative prophylaxis<\/strong> \u2014 cataract, corneal transplant, vitrectomy<\/li>\n<li><strong>Contact-lens-associated keratitis<\/strong> \u2014 Pseudomonas coverage is critical<\/li>\n<\/ul>\n<h2>Dosing<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Indication<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Dose<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Bacterial conjunctivitis<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">1\u20132 drops every 2 hours while awake for 2 days, then 1\u20132 drops every 4 hours for 5 more days<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Corneal ulcer (specialist)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">2 drops every 15 minutes for the first 6 hours, then every 30 minutes through day 1, then hourly through day 2, then 4 times daily<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Pre-operative prophylaxis<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">1 drop QID for 1\u20133 days before surgery<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Post-operative<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">1 drop QID for 7\u201314 days after surgery<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:12px 16px;margin:14px 0;border-radius:4px;font-size:14px;line-height:1.55;\"><strong style=\"color:#a94442;\">Antibiotic stewardship.<\/strong> Most acute conjunctivitis is viral or allergic, not bacterial. Routine fluoroquinolone use for any red eye is inappropriate and drives resistance. Reserve for confirmed bacterial infection (purulent discharge, no URTI, no allergic features) or specialist instruction (corneal ulcer, post-operative). For mild bacterial conjunctivitis, narrower-spectrum drops such as chloramphenicol or sodium fusidate are preferable where available.<\/div>\n<h2>Side Effects<\/h2>\n<p><strong>Local:<\/strong> stinging, burning on instillation (most common), conjunctival hyperaemia, foreign body sensation, lid margin crusting, ocular pruritus, photophobia.<\/p>\n<p><strong>Systemic (rare):<\/strong> headache, nausea, taste disturbance.<\/p>\n<p><strong>Allergic reactions:<\/strong> immediate-type hypersensitivity is rare but reported. Discontinue if rash, swelling, or severe itching develops.<\/p>\n<h2>Warnings &amp; Contraindications<\/h2>\n<ul>\n<li>Hypersensitivity to fluoroquinolones (ciprofloxacin, levofloxacin, moxifloxacin, norfloxacin, ofloxacin)<\/li>\n<li>Viral keratitis (herpes simplex, varicella zoster) \u2014 fluoroquinolones do not treat viral infections; concurrent viral keratitis can worsen if topical steroids are added inappropriately<\/li>\n<li>Fungal keratitis<\/li>\n<li>Acanthamoeba keratitis (especially in contact-lens users)<\/li>\n<li>Pregnancy \/ breastfeeding \u2014 minimal systemic absorption from eye drops; usually acceptable, but discuss with prescriber<\/li>\n<li>Children \u2014 usually safe from age 1 year for conjunctivitis; corneal ulcer dosing requires specialist supervision<\/li>\n<\/ul>\n<h2>Storage<\/h2>\n<p>Store at 15\u201325\u00b0C protected from light. Discard 28 days after first opening. Do not touch the dropper tip to your eye or any surface.<\/p>\n<h2 id=\"faqs\">Frequently Asked Questions<\/h2>\n<h3>When should I use Zuflo Eye Drop?<\/h3>\n<p>When bacterial conjunctivitis is suspected: thick yellow-green purulent discharge, mattered lashes on waking, no upper-respiratory symptoms, often unilateral. Most red eyes are viral or allergic \u2014 antibiotic drops are not first-line for those.<\/p>\n<h3>How long should I use Zuflo Eye Drop?<\/h3>\n<p>5\u20137 days for conjunctivitis. Symptoms usually improve within 48 hours; complete the full course even if eyes look normal. Prolonged use (&gt; 14 days) drives resistance.<\/p>\n<h3>Can I wear contact lenses while using Zuflo Eye Drop?<\/h3>\n<p>No. Stop wearing lenses for the duration of treatment and for at least 24 hours after symptoms resolve. Contact-lens-associated keratitis specifically requires lens cessation as part of cure.<\/p>\n<h3>What is the white precipitate I see in the eye?<\/h3>\n<p>Should be uncommon with Ofloxacin. If you see crystalline deposits, contact your ophthalmologist.<\/p>\n<h3>Is Zuflo Eye Drop safe in pregnancy?<\/h3>\n<p>Topical absorption is minimal and ophthalmic fluoroquinolones are generally considered safe in pregnancy when clearly indicated. Discuss with your prescriber.<\/p>\n<h3>What if symptoms don&#039;t improve in 48 hours?<\/h3>\n<p>Re-evaluate the diagnosis. The infection may be viral, fungal, or amoebic \u2014 fluoroquinolones don&#8217;t treat any of those. Persistent or worsening symptoms warrant urgent ophthalmology review.<\/p>\n<h3>Why not just use Zuflo Eye Drop for any red eye?<\/h3>\n<p>Most acute conjunctivitis is viral (adenovirus) or allergic. Topical antibiotics provide no benefit for those and contribute to fluoroquinolone-resistant strains of S. pneumoniae and S. aureus.<\/p>\n<h3>What if I get an allergic reaction?<\/h3>\n<p>Stop the drop immediately and contact your prescriber. Symptoms include increasing redness, lid swelling, severe itching, or rash spreading from the eye. Switch to a different antibiotic class.<\/p>\n<h3>Can Zuflo Eye Drop be used with other eye drops?<\/h3>\n<p>Yes, but separate by 5 minutes. If you use a steroid eye drop alongside, ensure the diagnosis is bacterial and not viral \u2014 steroids can devastate herpetic keratitis.<\/p>\n<h3>Why is this called a fluoroquinolone?<\/h3>\n<p>Ofloxacin is a synthetic antibiotic in the fluoroquinolone class \u2014 characterised by a fluorine atom on a quinolone ring. The class includes ciprofloxacin, levofloxacin, moxifloxacin, ofloxacin, and norfloxacin.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3>Other Eye-Care Medications<\/h3>\n<p>Customers viewing this product also consider these alternatives in our <a href=\"\/eye-care\/\">Eye Care<\/a> range:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/ciplox-d-eye-drops\/\">Ciplox-D Eye Drops (cipro+dex)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/gate-p-eye-drops\/\">Gate P Eye Drops (gatifloxacin)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/genticyn-eye-drop\/\">Genticyn Eye Drop (gentamicin)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/milflox-eye-drop\/\">Milflox Eye Drop (moxifloxacin)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/oflox-eye-drop\/\">Oflox Eye Drop (ofloxacin)<\/a><\/li>\n<\/ul>\n<h3>Medical Disclaimer<\/h3>\n<p style=\"font-size:13px;color:#555;\">The information on this page is for educational purposes only and is not a substitute for medical advice from a qualified ophthalmologist or optometrist. Eye conditions can rapidly threaten sight \u2014 sudden vision loss, severe pain, or trauma is an ophthalmology emergency. Always consult an eye-care professional before starting, stopping, or changing any treatment.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Zuflo (ofloxacin 0.3%) \u2014 fluoroquinolone eye drop for bacterial conjunctivitis, blepharitis and corneal ulcers. Day-1 frequent loading, then four-times-daily taper.<\/p>\n","protected":false},"featured_media":51398,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3343,3342],"product_tag":[],"class_list":{"0":"post-51397","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-eye-care","8":"product_cat-general-health","10":"first","11":"outofstock","12":"shipping-taxable","13":"purchasable","14":"product-type-variable","15":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product\/51397","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/comments?post=51397"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/media\/51398"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/media?parent=51397"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product_brand?post=51397"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product_cat?post=51397"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product_tag?post=51397"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}