{"id":52331,"date":"2023-09-20T09:31:52","date_gmt":"2023-09-20T09:31:52","guid":{"rendered":"https:\/\/medsname.com\/azicip\/"},"modified":"2026-04-30T10:18:14","modified_gmt":"2026-04-30T10:18:14","slug":"azicip","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/azicip\/","title":{"rendered":"Azicip"},"content":{"rendered":"

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\u26a1 Rychl\u00e1 odpov\u011b\u010f \u2014 Co je Azicip?<\/h3>\n

Azicip je tableta azithromycinu (250 mg \/ 500 mg, Cipla)<\/strong> \u2014 makrolidov\u00e9 antibiotikum pro infekce horn\u00edch\/doln\u00edch d\u00fdchac\u00edch cest, chlamydie, kapavku (v kombinaci s ceftriaxonem), \u010dern\u00fd ka\u0161el a cestovatelsk\u00fd pr\u016fjem. D\u00e1vkov\u00e1n\u00ed jednou denn\u011b. Dlouh\u00fd polo\u010das umo\u017e\u0148uje kr\u00e1tk\u00e9 l\u00e9\u010debn\u00e9 k\u00fary.<\/p>\n<\/div>\n

Pro\u010d objedn\u00e1vat z MedsBase?<\/strong> Dod\u00e1v\u00e1no od v\u00fdrobce certifikovan\u00e9ho WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Doprava po cel\u00e9m sv\u011bt\u011b \u00b7 1 400+ ov\u011b\u0159en\u00fdch recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a><\/div>\n

\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n

Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n

Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n

Jak Azicip funguje<\/h2>\n

Azicip obsahuje Azithromycin<\/strong>, azithromycin, makrolidov\u00e9 antibiotikum, kter\u00e9 se v\u00e1\u017ee na 50S podjednotku bakteri\u00e1ln\u00ed ribozom\u00e1ln\u00ed podjednotky a blokuje prodlu\u017eov\u00e1n\u00ed peptidov\u00e9ho \u0159et\u011bzce, \u010d\u00edm\u017e zastavuje bakteri\u00e1ln\u00ed synt\u00e9zu b\u00edlkovin. Makrolidy jsou ve standardn\u00edch d\u00e1vk\u00e1ch bakteriostatick\u00e9, ale ve vy\u0161\u0161\u00edch koncentrac\u00edch baktericidn\u00ed proti citliv\u00fdm organism\u016fm. Spektrum zahrnuje druhy Streptococcus (v\u010detn\u011b n\u011bkter\u00fdch penicilin-rezistentn\u00edch pneumokok\u016f), Mycoplasma pneumoniae, Chlamydia trachomatis a pneumoniae, Legionella, Bordetella a Helicobacter pylori. \u00da\u010dinnost proti stafylokok\u016fm je nejist\u00e1 kv\u016fli roz\u0161\u00ed\u0159en\u00e9 rezistenci na makrolidy a v\u011bt\u0161ina Enterobacteriaceae je p\u0159irozen\u011b rezistentn\u00ed.<\/p>\n

Azithromycin je nej\u010dast\u011bji pou\u017e\u00edvan\u00fd makrolid d\u00edky sv\u00e9mu prodlou\u017een\u00e9mu polo\u010dasu (~68 hodin intracelul\u00e1rn\u011b), jednoduch\u00e9mu d\u00e1vkovac\u00edmu sch\u00e9matu a ni\u017e\u0161\u00ed inhibici CYP3A4 ve srovn\u00e1n\u00ed s erytromycinem nebo klarithromycinem.<\/p>\n

Indikace & d\u00e1vkov\u00e1n\u00ed<\/h2>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
D\u00e1vkov\u00e1n\u00ed pro dosp\u011bl\u00e9<\/caption>\n
Indikace<\/th>\nD\u00e1vka<\/th>\nD\u00e9lka<\/th>\n<\/tr>\n<\/thead>\n
Akutn\u00ed bakteri\u00e1ln\u00ed sinusitida \/ m\u00edrn\u00e1 komunitn\u00ed pneumonie<\/td>\n500 mg prvn\u00ed den, pot\u00e9 250 mg denn\u011b \u2014 celkem 5 dn\u00ed<\/td>\n5 dn\u00ed<\/td>\n<\/tr>\n
Akutn\u00ed bakteri\u00e1ln\u00ed sinusitida (alternativn\u00ed re\u017eim)<\/td>\n500 mg jednou denn\u011b<\/td>\n3 dny<\/td>\n<\/tr>\n
Streptokokov\u00e1 faryngitida (p\u0159i alergii na penicilin)<\/td>\n500 mg prvn\u00ed den, pot\u00e9 250 mg denn\u011b<\/td>\n5 dn\u00ed<\/td>\n<\/tr>\n
Nekomplikovan\u00e1 chlamydiov\u00e1 uretritida\/cervicitida<\/td>\n1 g jednor\u00e1zov\u00e1 d\u00e1vka<\/td>\nJednor\u00e1zov\u00e1 d\u00e1vka<\/td>\n<\/tr>\n
Nekomplikovan\u00e1 kapavka (v kombinaci s ceftriaxonem)<\/td>\n1 g jednor\u00e1zov\u00e1 d\u00e1vka<\/td>\nJednor\u00e1zov\u00e1 d\u00e1vka<\/td>\n<\/tr>\n
Mycoplasma genitalium (roz\u0161\u00ed\u0159en\u00fd re\u017eim)<\/td>\n500 mg prvn\u00ed den, pot\u00e9 250 mg denn\u011b<\/td>\n5 dn\u00ed<\/td>\n<\/tr>\n
Pr\u016fjem cestovatel\u016f (v rozvojov\u00fdch zem\u00edch)<\/td>\n500 mg\u20131 g denn\u011b<\/td>\n3 dny<\/td>\n<\/tr>\n
\u010cern\u00fd ka\u0161el (pertuse)<\/td>\n500 mg prvn\u00ed den, pot\u00e9 250 mg denn\u011b<\/td>\n5 dn\u00ed<\/td>\n<\/tr>\n
Profylaxe MAC u HIV (CD4 < 50)<\/td>\n1,2 g jednou t\u00fddn\u011b<\/td>\nA\u017e do CD4 > 100 trvale<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
\u26a0 Prodlou\u017een\u00ed QT intervalu \u2014 varov\u00e1n\u00ed t\u0159\u00eddy<\/strong><\/p>\n
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V\u0161echna makrolidov\u00e1 antibiotika mohou prodlou\u017eit QT interval a vyvolat torsade de pointes \u2014 zejm\u00e9na u pacient\u016f s vrozen\u00fdm dlouh\u00fdm QT intervalem, poruchou elektrolyt\u016f (n\u00edzk\u00e9 K+ \/ Mg2+), bradykardi\u00ed, sou\u010dasn\u00fdm u\u017e\u00edv\u00e1n\u00edm l\u00e9k\u016f prodlu\u017euj\u00edc\u00edch QT interval (azoly, fluorochinolony, citalopram, ondansetron, n\u011bkter\u00e1 antipsychotika, n\u011bkter\u00e1 antiarytmika) nebo v\u00fdznamn\u00fdm srde\u010dn\u00edm onemocn\u011bn\u00edm. Azithromycin obdr\u017eel v roce 2013 aktualizaci \u010dern\u00e9ho r\u00e1me\u010dku FDA pot\u00e9, co observa\u010dn\u00ed data spojila jeho u\u017e\u00edv\u00e1n\u00ed s mal\u00fdm absolutn\u00edm zv\u00fd\u0161en\u00edm kardiovaskul\u00e1rn\u00ed mortality u pacient\u016f se zv\u00fd\u0161en\u00fdm kardiovaskul\u00e1rn\u00edm rizikem. Pacienti se stabiln\u00edm kardiovaskul\u00e1rn\u00edm onemocn\u011bn\u00edm mohou obvykle makrolidy u\u017e\u00edvat bezpe\u010dn\u011b; vysoce rizikov\u00ed pacienti \u2014 zn\u00e1m\u00fd dlouh\u00fd QT interval, ned\u00e1vn\u00fd infarkt myokardu, pokro\u010dil\u00e9 srde\u010dn\u00ed selh\u00e1n\u00ed \u2014 mohou pot\u0159ebovat alternativn\u00ed t\u0159\u00eddu l\u00e9k\u016f.<\/p>\n<\/div>\n<\/div>\n

Vedlej\u0161\u00ed \u00fa\u010dinky<\/h2>\n