{"id":52655,"date":"2023-09-20T09:36:17","date_gmt":"2023-09-20T09:36:17","guid":{"rendered":"https:\/\/medsname.com\/oframax-injection\/"},"modified":"2026-05-19T05:01:18","modified_gmt":"2026-05-19T05:01:18","slug":"oframax-injection","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/oframax-injection\/","title":{"rendered":"Oframax Injekce"},"content":{"rendered":"

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\u26a1 Rychl\u00e1 odpov\u011b\u010f \u2014 Co je Oframax Injection?<\/h3>\n

Oframax Injection je ceftriaxonov\u00e1 IV \/ IM injekce (Ranbaxy)<\/strong> \u2014 cefalosporin t\u0159et\u00ed generace pou\u017e\u00edvan\u00fd v nemocnic\u00edch pro t\u011b\u017ekou komunitn\u00ed pneumonii, pyelonefritidu, bakteri\u00e1ln\u00ed meningitidu (2 g IV ka\u017ed\u00fdch 12 h), kapavku a chirurgickou profylaxi.<\/p>\n<\/div>\n

Pro\u010d objedn\u00e1vat z MedsBase?<\/strong> Dod\u00e1v\u00e1no od v\u00fdrobce certifikovan\u00e9ho WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Doprava po cel\u00e9m sv\u011bt\u011b \u00b7 1 400+ ov\u011b\u0159en\u00fdch recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a><\/div>\n

\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n

Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n

Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n

Jak Oframax Injection funguje<\/h2>\n

Oframax Injection obsahuje Ceftriaxon<\/strong>, cefalosporin t\u0159et\u00ed generace se silnou \u00fa\u010dinnost\u00ed proti gramnegativn\u00edm bakteri\u00edm (v\u010detn\u011b mnoha Enterobacteriaceae, Neisseria spp. a Haemophilus influenzae) a dobrou penetrac\u00ed do CNS. \u00da\u010dinnost proti streptokok\u016fm je zachov\u00e1na; \u00fa\u010dinnost proti stafylokok\u016fm je slab\u0161\u00ed ne\u017e u cefalosporin\u016f prvn\u00ed generace. P\u016fsob\u00ed baktericidn\u011b inhibic\u00ed tvorby bun\u011b\u010dn\u00e9 st\u011bny. Rezistence vznik\u00e1 prost\u0159ednictv\u00edm extended-spectrum beta-laktam\u00e1z (ESBL), AmpC a sn\u00ed\u017een\u00e9 permeability porin\u016f \u2014 \u017e\u00e1dn\u00fd z t\u011bchto cefalosporin\u016f by nem\u011bl b\u00fdt pou\u017e\u00edv\u00e1n empiricky, pokud je pravd\u011bpodobn\u00e1 p\u0159\u00edtomnost organism\u016f produkuj\u00edc\u00edch ESBL\/AmpC.<\/p>\n

Indikace & d\u00e1vkov\u00e1n\u00ed<\/h2>\n\n\n\n\n\n\n\n\n\n\n
D\u00e1vkov\u00e1n\u00ed pro dosp\u011bl\u00e9 (injek\u010dn\u00ed)<\/caption>\n
Indikace<\/th>\nStandardn\u00ed d\u00e1vka<\/th>\nD\u00e9lka<\/th>\n<\/tr>\n<\/thead>\n
Komunitn\u00ed pneumonie (CAP, hospitalizovan\u00ed)<\/td>\n1\u20132 g IV\/IM jednou denn\u011b<\/td>\n5\u20137 dn\u00ed<\/td>\n<\/tr>\n
Pyelonefritida \/ komplikovan\u00e1 UTI<\/td>\n1\u20132 g i.v. 1\u00d7 denn\u011b<\/td>\n7\u201314 dn\u00ed<\/td>\n<\/tr>\n
Bakteri\u00e1ln\u00ed meningitida (po lumb\u00e1ln\u00ed punkci)<\/td>\n2 g i.v. ka\u017ed\u00fdch 12 hodin (maxim\u00e1ln\u00ed d\u00e1vkov\u00e1n\u00ed pro CNS)<\/td>\n10\u201314 dn\u00ed<\/td>\n<\/tr>\n
Empirick\u00e1 l\u00e9\u010dba sepse p\u0159ed mikrobiologick\u00fdm vy\u0161et\u0159en\u00edm<\/td>\n2 g i.v. 1\u00d7 denn\u011b (kombinovat p\u0159i t\u011b\u017ek\u00e9m pr\u016fb\u011bhu)<\/td>\nPodle kultivace<\/td>\n<\/tr>\n
Diseminovan\u00e1 gonokokov\u00e1 infekce<\/td>\n1 g i.v.\/i.m. 1\u00d7 denn\u011b<\/td>\n7 dnech<\/td>\n<\/tr>\n
Chirurgick\u00e1 profylaxe<\/td>\n1 g i.v. p\u0159i indukci<\/td>\nJednor\u00e1zov\u00e1 d\u00e1vka<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Nekompatibilita s v\u00e1pn\u00edkem (ceftriaxon):<\/strong> nikdy nesm\u00ed b\u00fdt pod\u00e1v\u00e1n sou\u010dasn\u011b s intraven\u00f3zn\u00edmi roztoky obsahuj\u00edc\u00edmi v\u00e1pn\u00edk u novorozenc\u016f \u2264 28 dn\u016f \u2013 byly hl\u00e1\u0161eny fat\u00e1ln\u00ed precipit\u00e1ty v plic\u00edch\/ledvin\u00e1ch. U star\u0161\u00edch pacient\u016f dodr\u017eet minim\u00e1ln\u011b 48hodinov\u00fd interval p\u0159i nutnosti pod\u00e1n\u00ed obou p\u0159\u00edpravk\u016f.<\/p>\n

\u00daprava d\u00e1vkov\u00e1n\u00ed p\u0159i ren\u00e1ln\u00edm posti\u017een\u00ed:<\/strong> v\u0161echny peror\u00e1ln\u00ed cefalosporiny vy\u017eaduj\u00ed \u00fapravu d\u00e1vky p\u0159i CrCl pod 30 \u2014 u t\u011b\u017ek\u00e9ho ren\u00e1ln\u00edho posti\u017een\u00ed se pora\u010fte s klinick\u00fdm farmaceutem. Ceftriaxon (kter\u00fd se vylu\u010duje \u017elu\u010d\u00ed) NEPOT\u0158EBUJE \u00fapravu d\u00e1vky p\u0159i ren\u00e1ln\u00ed insuficienci.<\/p>\n

Vedlej\u0161\u00ed \u00fa\u010dinky<\/h2>\n