{"id":52776,"date":"2023-09-20T09:37:58","date_gmt":"2023-09-20T09:37:58","guid":{"rendered":"https:\/\/medsname.com\/raxitid\/"},"modified":"2026-04-30T10:18:09","modified_gmt":"2026-04-30T10:18:09","slug":"raxitid","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/raxitid\/","title":{"rendered":"Raxitid"},"content":{"rendered":"

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\u26a1 Rychl\u00e1 odpov\u011b\u010f \u2014 Co je Raxitid?<\/h3>\n

Raxitid je tableta roxithromycinu (150 mg \/ 300 mg, Ranbaxy)<\/strong> \u2014 makrolidov\u00e9 antibiotikum s del\u0161\u00edm polo\u010dasem a lep\u0161\u00ed sn\u00e1\u0161enlivost\u00ed v za\u017e\u00edvac\u00edm traktu ne\u017e erytromycin. Pou\u017e\u00edv\u00e1 se p\u0159i infekc\u00edch d\u00fdchac\u00edch cest, z\u00e1n\u011btu vedlej\u0161\u00edch nosn\u00edch dutin, z\u00e1n\u011btu st\u0159edn\u00edho ucha a infekc\u00edch k\u016f\u017ee \/ m\u011bkk\u00fdch tk\u00e1n\u00ed. D\u00e1vkov\u00e1n\u00ed jednou nebo dvakr\u00e1t denn\u011b.<\/p>\n<\/div>\n

Pro\u010d objedn\u00e1vat z MedsBase?<\/strong> Dod\u00e1v\u00e1no od v\u00fdrobce certifikovan\u00e9ho WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Doprava po cel\u00e9m sv\u011bt\u011b \u00b7 1 400+ ov\u011b\u0159en\u00fdch recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a><\/div>\n

\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n

Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n

Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n

Jak Raxitid funguje<\/h2>\n

Raxitid obsahuje Roxithromycin<\/strong>, azithromycin, makrolidov\u00e9 antibiotikum, kter\u00e9 se v\u00e1\u017ee na 50S podjednotku bakteri\u00e1ln\u00ed ribozom\u00e1ln\u00ed podjednotky a blokuje prodlu\u017eov\u00e1n\u00ed peptidov\u00e9ho \u0159et\u011bzce, \u010d\u00edm\u017e zastavuje bakteri\u00e1ln\u00ed synt\u00e9zu b\u00edlkovin. Makrolidy jsou ve standardn\u00edch d\u00e1vk\u00e1ch bakteriostatick\u00e9, ale ve vy\u0161\u0161\u00edch koncentrac\u00edch baktericidn\u00ed proti citliv\u00fdm organism\u016fm. Spektrum zahrnuje druhy Streptococcus (v\u010detn\u011b n\u011bkter\u00fdch penicilin-rezistentn\u00edch pneumokok\u016f), Mycoplasma pneumoniae, Chlamydia trachomatis a pneumoniae, Legionella, Bordetella a Helicobacter pylori. \u00da\u010dinnost proti stafylokok\u016fm je nejist\u00e1 kv\u016fli roz\u0161\u00ed\u0159en\u00e9 rezistenci na makrolidy a v\u011bt\u0161ina Enterobacteriaceae je p\u0159irozen\u011b rezistentn\u00ed.<\/p>\n

Roxithromycin nab\u00edz\u00ed lep\u0161\u00ed peror\u00e1ln\u00ed biologickou dostupnost a del\u0161\u00ed polo\u010das ne\u017e erytromycin, m\u00e9n\u011b interakc\u00ed s CYP a d\u00e1vkov\u00e1n\u00ed jednou nebo dvakr\u00e1t denn\u011b. Pou\u017e\u00edv\u00e1 se v mnoha zem\u00edch p\u0159i infekc\u00edch d\u00fdchac\u00edch cest, i kdy\u017e dostupnost v USA\/Velk\u00e9 Brit\u00e1nii je omezen\u00e1.<\/p>\n

Indikace & d\u00e1vkov\u00e1n\u00ed<\/h2>\n\n\n\n\n\n\n\n\n
D\u00e1vkov\u00e1n\u00ed pro dosp\u011bl\u00e9<\/caption>\n
Indikace<\/th>\nD\u00e1vka<\/th>\nD\u00e9lka<\/th>\n<\/tr>\n<\/thead>\n
Lehk\u00e1 a\u017e st\u0159edn\u011b t\u011b\u017ek\u00e1 infekce d\u00fdchac\u00edch cest<\/td>\n150 mg dvakr\u00e1t denn\u011b NEBO 300 mg jednou denn\u011b<\/td>\n5\u201310 dn\u00ed<\/td>\n<\/tr>\n
Z\u00e1n\u011bt vedlej\u0161\u00edch nosn\u00edch dutin \/ z\u00e1n\u011bt st\u0159edn\u00edho ucha (alergie na penicilin)<\/td>\n150 mg dvakr\u00e1t denn\u011b<\/td>\n10 dn\u00ed<\/td>\n<\/tr>\n
Infekce k\u016f\u017ee a m\u011bkk\u00fdch tk\u00e1n\u00ed<\/td>\n150 mg dvakr\u00e1t denn\u011b<\/td>\n7\u201310 dn\u00ed<\/td>\n<\/tr>\n
Atypick\u00e1 pneumonie (Mycoplasma, Chlamydia)<\/td>\n300 mg jednou denn\u011b<\/td>\n14 dn\u00ed<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
\u26a0 Prodlou\u017een\u00ed QT intervalu \u2014 varov\u00e1n\u00ed t\u0159\u00eddy<\/strong><\/p>\n
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V\u0161echna makrolidov\u00e1 antibiotika mohou prodlou\u017eit QT interval a vyvolat torsade de pointes \u2014 zejm\u00e9na u pacient\u016f s vrozen\u00fdm dlouh\u00fdm QT intervalem, poruchou elektrolyt\u016f (n\u00edzk\u00e9 K+ \/ Mg2+), bradykardi\u00ed, sou\u010dasn\u00fdm u\u017e\u00edv\u00e1n\u00edm l\u00e9k\u016f prodlu\u017euj\u00edc\u00edch QT interval (azoly, fluorochinolony, citalopram, ondansetron, n\u011bkter\u00e1 antipsychotika, n\u011bkter\u00e1 antiarytmika) nebo v\u00fdznamn\u00fdm srde\u010dn\u00edm onemocn\u011bn\u00edm. Azithromycin obdr\u017eel v roce 2013 aktualizaci \u010dern\u00e9ho r\u00e1me\u010dku FDA pot\u00e9, co observa\u010dn\u00ed data spojila jeho u\u017e\u00edv\u00e1n\u00ed s mal\u00fdm absolutn\u00edm zv\u00fd\u0161en\u00edm kardiovaskul\u00e1rn\u00ed mortality u pacient\u016f se zv\u00fd\u0161en\u00fdm kardiovaskul\u00e1rn\u00edm rizikem. Pacienti se stabiln\u00edm kardiovaskul\u00e1rn\u00edm onemocn\u011bn\u00edm mohou obvykle makrolidy u\u017e\u00edvat bezpe\u010dn\u011b; vysoce rizikov\u00ed pacienti \u2014 zn\u00e1m\u00fd dlouh\u00fd QT interval, ned\u00e1vn\u00fd infarkt myokardu, pokro\u010dil\u00e9 srde\u010dn\u00ed selh\u00e1n\u00ed \u2014 mohou pot\u0159ebovat alternativn\u00ed t\u0159\u00eddu l\u00e9k\u016f.<\/p>\n<\/div>\n<\/div>\n

Vedlej\u0161\u00ed \u00fa\u010dinky<\/h2>\n