{"id":53139,"date":"2023-09-20T09:43:06","date_gmt":"2023-09-20T09:43:06","guid":{"rendered":"https:\/\/medsname.com\/carditrex\/"},"modified":"2026-04-30T16:30:26","modified_gmt":"2026-04-30T16:30:26","slug":"carditrex","status":"publish","type":"product","link":"https:\/\/medsbase.com\/carditrex\/","title":{"rendered":"Carditrex"},"content":{"rendered":"<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<h3 style=\"margin-top:0;\">Quick Answer<\/h3>\n<p style=\"margin-bottom:0;\"><strong>Carditrex<\/strong> \u2014 Methotrexate 2.5 mg (Cipla Inc). Antifolate for haematological malignancies (ALL, lymphoma), trophoblastic disease, severe psoriasis, rheumatoid arthritis. Multiple dose schedules (weekly low-dose for autoimmune; high-dose IV for cancer with leucovorin rescue).<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f7f7f7;border-left:4px solid #2c7cb0;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<p style=\"margin:0 0 6px 0;\"><strong>What you get with MedsBase:<\/strong><\/p>\n<ul style=\"margin:6px 0 0 22px;padding:0;list-style:disc;\">\n<li>WHO-GMP certified manufacturer<\/li>\n<li>Discreet plain-envelope packaging<\/li>\n<li>Worldwide shipping<\/li>\n<li>Rated by 1,400+ customers (<a href=\"https:\/\/medsbase.com\/reviews\/\">read reviews<\/a>)<\/li>\n<\/ul>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"background:#eef7ee;border-left:4px solid #4caf50;padding:10px 14px;margin:14px 0;border-radius:3px;\">\ud83d\udce6 <strong>Reshipment Assurance:<\/strong> if your order has not arrived 20 business days after dispatch, we reship it at no extra cost. <a href=\"https:\/\/medsbase.com\/medsbase-re-shipment-assurance-policy\/\">Read the policy<\/a>.<\/p>\n<h3>Why order from MedsBase<\/h3>\n<p>Carditrex ships from a WHO-GMP certified manufacturer in plain packaging, billed through a regulated payment processor (the statement descriptor reads a regulated card-payment processor \u2014 never MedsBase or any medication name). Every order carries our 20-business-day Reshipment Assurance.<\/p>\n<div class=\"medsbase-specialist-strip\" style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<p style=\"margin:0;\"><strong>\u26a0\ufe0f Specialist-supervised cancer therapy<\/strong> \u2014 this medication is started, monitored, and stopped by an oncologist or haematologist. Dosing depends on tumour type, stage, body surface area, organ function, and concomitant therapy. Self-treatment is not appropriate; the information below is educational and supports informed conversations with your specialist.<\/p>\n<\/div>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:12px 16px;margin:14px 0;border-radius:3px;\"><strong>WEEKLY dosing only (autoimmune) + folic acid supplementation<\/strong><br \/>MTX for autoimmune disease is taken ONCE A WEEK \u2014 daily dosing has caused fatal toxicity. Always confirm the schedule. Co-prescribe folic acid 5 mg\/week (different day) to reduce toxicity. Mandatory FBC, LFTs, renal function before each weekly dose for first 6 months. Cancer high-dose IV regimens require leucovorin rescue + plasma MTX monitoring.<\/div>\n<h2 id=\"faqs\">Frequently Asked Questions<\/h2>\n<h3>When is this used?<\/h3>\n<p>Antifolate for haematological malignancies (ALL, lymphoma), trophoblastic disease, severe psoriasis, rheumatoid arthritis. Multiple dose schedules (weekly low-dose for autoimmune; high-dose IV for cancer with leucovorin rescue). Specific protocols are oncologist-determined.<\/p>\n<h3>Side effects?<\/h3>\n<p>Class-typical: myelosuppression, nausea, alopecia, mucositis, fatigue. Specific toxicities depend on the drug \u2014 see safety boxes above.<\/p>\n<h3>Drug interactions?<\/h3>\n<p>Cancer chemotherapy has multiple critical interactions. Always disclose all medications including herbals and supplements. Anticoagulants, anticonvulsants, antibiotics, antifungals, and antivirals all need review.<\/p>\n<h3>Pregnancy?<\/h3>\n<p>Cytotoxic chemotherapy is teratogenic. Effective contraception during and for 6 months after for both partners.<\/p>\n<h3>Monitoring?<\/h3>\n<p>Specialist-determined \u2014 typically FBC, renal\/liver function, electrolytes before each cycle. Drug-specific tests (echocardiogram for anthracyclines, audiometry for cisplatin, etc.).<\/p>\n<h3>What if I miss a dose?<\/h3>\n<p>Oral cytotoxics: skip the missed dose, do not double up, contact your oncology team. IV: dosing is strictly scheduled \u2014 discuss any delay or missed cycle with the specialist.<\/p>\n<h3>Storage?<\/h3>\n<p>Oral cytotoxics: at room temperature, away from children, in original blister. Hand washing after handling tablets. Pregnant household members should not handle broken tablets.<\/p>\n<h3>Vaccines?<\/h3>\n<p>Live vaccines are contraindicated during chemotherapy. Inactivated vaccines (annual influenza, pneumococcal) are recommended. Coordinate with oncology for timing.<\/p>\n<h3>Long-term complications?<\/h3>\n<p>Class-dependent: secondary malignancy, infertility, cardiotoxicity, neuropathy. Discuss with oncology \u2014 fertility preservation may be relevant before starting.<\/p>\n<h3>When is treatment finished?<\/h3>\n<p>Determined by tumour response, treatment intent (curative vs palliative), and toxicity. Imaging and clinical assessment guide ongoing therapy.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h2>Other Cancer Medications<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/xeloda\/\">Xeloda<\/a> \u2014 capecitabine 500 mg \u2014 oral 5-FU prodrug for breast\/colorectal\/gastric cancers<\/li>\n<li><a href=\"https:\/\/medsbase.com\/altraz\/\">Altraz<\/a> \u2014 anastrozole 1 mg \u2014 aromatase inhibitor for post-menopausal breast cancer<\/li>\n<li><a href=\"https:\/\/medsbase.com\/xbira\/\">Xbira<\/a> \u2014 abiraterone 250 mg \u2014 CYP17 inhibitor for metastatic prostate cancer<\/li>\n<li><a href=\"https:\/\/medsbase.com\/zoldria\/\">Zoldria<\/a> \u2014 zoledronic acid IV \u2014 for bone metastases and hypercalcaemia<\/li>\n<li><a href=\"https:\/\/medsbase.com\/actorise\/\">Actorise<\/a> \u2014 darbepoetin alfa \u2014 for chemotherapy-induced anaemia<\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:12px 16px;margin:18px 0;border-radius:3px;font-size:.95em;\"><strong>Medical Disclaimer:<\/strong> Cancer therapy is highly individualised. Specific drug, dose, schedule, monitoring, and supportive care must be determined by a qualified oncologist or haematologist based on tumour biology, staging, comorbidities, and goals of care. This information is educational; it does not substitute for professional medical advice.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Carditrex (Methotrexate 2.5 mg) \u2014 Cipla antifolate for haematological malignancies, severe psoriasis, and rheumatoid arthritis. WEEKLY dosing for autoimmune use only.<\/p>\n","protected":false},"featured_media":53140,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3595,3141,3223],"product_tag":[],"class_list":{"0":"post-53139","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-cancer-medication","7":"product_cat-category-overview","8":"product_cat-chronic-conditions","10":"first","11":"outofstock","12":"shipping-taxable","13":"purchasable","14":"product-type-variable","15":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product\/53139","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/comments?post=53139"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/media\/53140"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/media?parent=53139"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product_brand?post=53139"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product_cat?post=53139"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product_tag?post=53139"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}