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Aziderm Cream<\/strong> je topick\u00fd kr\u00e9m obsahuj\u00edc\u00ed azelaic acid 20%<\/strong> od spole\u010dnosti Micro Labs \u2014 jedna z nejuniverz\u00e1ln\u011bj\u0161\u00edch dermatologick\u00fdch \u00fa\u010dinn\u00fdch l\u00e1tek pou\u017e\u00edvan\u00fdch dnes. Je to l\u00e9\u010dba prvn\u00ed volby pro papulopustul\u00f3zn\u00ed r\u016f\u017eovku<\/strong>, terapie zalo\u017een\u00e1 na d\u016fkazech pro m\u00edrn\u00e9 a\u017e st\u0159edn\u011b t\u011b\u017ek\u00e9 akn\u00e9 vulgaris<\/strong>, a bezpe\u010dn\u00e1 volba pro t\u011bhotn\u00e9 p\u0159i melasm\u011b a postinflama\u010dn\u00ed hyperpigmentaci<\/strong>. Aplikujte tenkou vrstvu na \u010distou, suchou poko\u017eku dvakr\u00e1t denn\u011b<\/strong> (r\u00e1no a ve\u010der). N\u00e1stup \u00fa\u010dinku: viditeln\u00e9 sn\u00ed\u017een\u00ed zarudnut\u00ed u r\u016f\u017eovky za 4\u20136 t\u00fddn\u016f; \u00fastup akn\u00e9 za 8\u201312 t\u00fddn\u016f; zesv\u011btlen\u00ed pigmentace za 12\u201316 t\u00fddn\u016f. T\u0159i hlavn\u00ed vedlej\u0161\u00ed \u00fa\u010dinky jsou kr\u00e1tk\u00e9 p\u00e1len\u00ed\/teplo p\u0159i prvn\u00ed aplikaci (obvykle ustoup\u00ed do t\u00fddne), m\u00edrn\u00e1 p\u0159echodn\u00e1 suchost a \u2014 vz\u00e1cn\u011b \u2014 pocit brn\u011bn\u00ed. Azelaov\u00e1 kyselina je FDA t\u011bhotensk\u00e1 kategorie B<\/strong> (vhodn\u00e1 pro t\u011bhotenstv\u00ed a kojen\u00ed), nezvy\u0161uje citlivost na slunce a lze ji kombinovat s v\u011bt\u0161inou dal\u0161\u00edch aktivn\u00edch l\u00e1tek v\u010detn\u011b retinoid\u016f, niacinamidu a vitaminu C.<\/p>\n<\/div>\n \ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n Aziderm kr\u00e9m je topick\u00fd kr\u00e9m obsahuj\u00edc\u00ed azelaic acid 20%<\/strong>, nasycenou dev\u00edtiuhl\u00edkatou dikarboxylovou kyselinu , vyr\u00e1b\u011bn\u00fd spole\u010dnost\u00ed Micro Labs a dod\u00e1van\u00fd v tub\u011b o hmotnosti 15 g. Azelaov\u00e1 kyselina je<\/strong> kter\u00e1 se p\u0159irozen\u011b vyskytuje v obilovin\u00e1ch, jako je p\u0161enice, \u017eito a je\u010dmen. V dermatologii pat\u0159\u00ed mezi vz\u00e1cn\u00e9 \u00fa\u010dinn\u00e9 l\u00e1tky, kter\u00e9 \u0159e\u0161\u00ed t\u0159i samostatn\u00e9 patologie<\/strong> \u2014 z\u00e1n\u011btlivou r\u016f\u017eovku, akn\u00e9 vulgaris a hyperpigmentaci \u2014 kombinac\u00ed protiz\u00e1n\u011btliv\u00fdch, antimikrobi\u00e1ln\u00edch a tyrosin\u00e1zu inhibuj\u00edc\u00edch \u00fa\u010dink\u016f.<\/p>\n Proto\u017ee je T\u011bhotensk\u00e1 kategorie B<\/strong> a proto\u017ee nevyvol\u00e1v\u00e1 fotosenzitivitu, zten\u010dov\u00e1n\u00ed ani olupov\u00e1n\u00ed poko\u017eky jako retinoidy, je kyselina azelaov\u00e1 \u010dasto prvn\u00ed volbou pro pacienty, kte\u0159\u00ed nesn\u00e1\u0161ej\u00ed nebo by nem\u011bli pou\u017e\u00edvat retinoidy, hydrochinon nebo topick\u00e9 steroidy.<\/p>\n Kyselina azelaov\u00e1 p\u016fsob\u00ed \u010dty\u0159mi r\u016fzn\u00fdmi mechanismy, co\u017e vysv\u011btluje jej\u00ed neobvykle \u0161irok\u00e9 vyu\u017eit\u00ed:<\/p>\n Kyselina azelaov\u00e1 je jedn\u00edm ze t\u0159\u00ed l\u00e9k\u016f prvn\u00ed volby pro lok\u00e1ln\u00ed l\u00e9\u010dbu papulopustul\u00f3zn\u00ed r\u016f\u017eovky<\/strong>, spolu s topick\u00fdm ivermektinem 1% (Ivrea Cream<\/a> \/ Soolantra) a topick\u00fd metronidazol. D\u016fkazn\u00ed z\u00e1kladna pro azelaovou kyselinu u r\u016f\u017eovky vych\u00e1z\u00ed ze dvou 12t\u00fddenn\u00edch randomizovan\u00fdch kontrolovan\u00fdch studi\u00ed (Thiboutot 2003, Elewski 2003), kter\u00e9 prok\u00e1zaly v\u00fdrazn\u011b v\u011bt\u0161\u00ed sn\u00ed\u017een\u00ed z\u00e1n\u011btliv\u00fdch l\u00e9z\u00ed (papuly a pustuly) a eryt\u00e9mu ve srovn\u00e1n\u00ed s placebem.<\/p>\n O\u010dek\u00e1van\u00fd \u010dasov\u00fd pr\u016fb\u011bh u Aziderm Cream p\u0159i r\u016f\u017eovce:<\/strong><\/p>\n Azelaov\u00e1 kyselina nesni\u017euje ne<\/strong> obli\u010dejov\u00e9 n\u00e1valy nebo z\u00e1kladn\u00ed zarudnut\u00ed erytematotelangiektatick\u00e9 r\u016f\u017eovky \u2014 pro to je, brimonidin 0,33% gel (Erythego)<\/a> vhodnou volbou. Mnoho pacient\u016f se sm\u00ed\u0161en\u00fdm typem r\u016f\u017eovky pou\u017e\u00edv\u00e1 azelaovou kyselinu pro z\u00e1n\u011btlivou slo\u017eku a brimonidin pro n\u00e1valy, st\u0159\u00eddav\u011b r\u00e1no.<\/p>\n Tip pro sn\u00e1\u0161enlivost:<\/strong> pokud je \u0161t\u00edp\u00e1n\u00ed v prvn\u00edm t\u00fddnu v\u00fdrazn\u00e9, za\u010dn\u011bte s aplikac\u00ed pouze ve\u010der po dobu 7 dn\u00ed, pot\u00e9 od druh\u00e9ho t\u00fddne p\u0159idejte rann\u00ed aplikaci. 90 % pacient\u016f zvl\u00e1dne dvakr\u00e1t denn\u00ed aplikaci bez probl\u00e9m\u016f do 2 t\u00fddn\u016f.<\/p>\n \u010cast\u00e9 (u 10\u201330 % u\u017eivatel\u016f, v\u011bt\u0161inou 1.\u20132. t\u00fdden, obvykle p\u0159echodn\u00e9):<\/strong><\/p>\n M\u00e9n\u011b \u010dast\u00e9:<\/strong> Nepozorov\u00e1no u kyseliny azelaov\u00e9:.<\/p>\n \u017e\u00e1dn\u00e1 fotosenzitivita, \u017e\u00e1dn\u00e1 kumulativn\u00ed atrofie, \u017e\u00e1dn\u00e9 teleangiekt\u00e1zie, \u017e\u00e1dn\u00e9 riziko v t\u011bhotenstv\u00ed, \u017e\u00e1dn\u00fd v\u00fdb\u011br bakteri\u00e1ln\u00ed rezistence, \u017e\u00e1dn\u00e9 \u201epro\u010di\u0161\u0165ov\u00e1n\u00ed\u201c nebo olupov\u00e1n\u00ed jako u retinoid\u016f.<\/strong> Kr\u00e9m Aziderm vs. jin\u00e9 topick\u00e9 p\u0159\u00edpravky na r\u016f\u017eovku\/akn\u00e9.<\/p>\nPro\u010d objedn\u00e1vat z MedsBase<\/h3>\n
Co je Aziderm kr\u00e9m?<\/h2>\n
Jak kyselina azelaov\u00e1 funguje<\/h2>\n
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Schv\u00e1len\u00e9 a v\u011bdecky podlo\u017een\u00e9 indikace<\/h2>\n
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Kr\u00e9m Aziderm pro r\u016f\u017eovku \u2014 co o\u010dek\u00e1vat<\/h2>\n
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D\u00e1vkov\u00e1n\u00ed Aziderm Cream a zp\u016fsob aplikace<\/h2>\n
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Vedlej\u0161\u00ed \u00fa\u010dinky & Sn\u00e1\u0161enlivost<\/h2>\n
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Topick\u00fd<\/h2>\n