{"id":55286,"date":"2024-01-27T15:56:38","date_gmt":"2024-01-27T15:56:38","guid":{"rendered":"https:\/\/medsname.com\/anaridex\/"},"modified":"2026-04-30T10:24:49","modified_gmt":"2026-04-30T10:24:49","slug":"anaridex","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/anaridex\/","title":{"rendered":"Anaridex"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Anaridex?<\/h3>\n<p style=\"margin:0;\"><strong>Anaridex<\/strong> je peror\u00e1ln\u00ed tableta od spole\u010dnosti Cipla obsahuj\u00edc\u00ed <strong>anastrozole 1 mg<\/strong> \u2014 selektivn\u00ed <strong>third-generation aromatase inhibitor<\/strong>. First-line adjuvant and metastatic therapy for <strong>hormone-receptor-positive breast cancer in postmenopausal women<\/strong>. Standard dose: <strong>1 mg jednou denn\u011b<\/strong>, typically for <strong>5&ndash;10 years<\/strong> in adjuvant setting. Anastrozole works by blocking conversion of androgens to oestrogen in peripheral tissue (~95% suppression). <strong>Postmenopausal women only<\/strong> &mdash; ineffective in premenopausal women (use <a href=\"https:\/\/medsbase.com\/cs\/tamilong\/\">tamoxifen<\/a> instead). Main side effects: hot flushes, joint and muscle pain (arthralgia in 30%), bone-density loss with fracture risk, vaginal dryness, mood change. Mandatory: baseline DEXA scan + repeat every 2 years; calcium + vitamin D supplementation; consider bisphosphonate or denosumab if osteopenia.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Co z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:0 0 24px 0;border-radius:4px;font-size:14px;\"><strong>\u26a0 Vy\u017eaduje se odborn\u00fd dohled.<\/strong> L\u00e9ky na rakovinu mus\u00ed b\u00fdt p\u0159edeps\u00e1ny o\u0161et\u0159uj\u00edc\u00edm onkologem s potvrzenou diagn\u00f3zou, vstupn\u00edm stagingem a definovan\u00fdm l\u00e9\u010debn\u00fdm pl\u00e1nem. Nikdy neza\u010d\u00ednejte, nep\u0159eru\u0161ujte, nem\u011b\u0148te d\u00e1vkov\u00e1n\u00ed ani neu\u017e\u00edvejte l\u00e9ky na rakovinu mimo onkologick\u00fd l\u00e9\u010debn\u00fd pl\u00e1n. V\u011bt\u0161ina l\u00e9k\u016f na rakovinu vy\u017eaduje pravideln\u00e9 monitorov\u00e1n\u00ed krevn\u00edch test\u016f (krevn\u00ed obraz, jatern\u00ed testy, funkce ledvin), je absolutn\u011b kontraindikov\u00e1na v t\u011bhotenstv\u00ed a m\u00e1 v\u00fdznamn\u00e9 l\u00e9kov\u00e9 interakce.<\/div>\n<div style=\"background:#f4f8fb;border:1px solid #d6e4ec;padding:12px 18px;margin:14px 0;border-radius:4px;font-size:14px;color:#3a5160;text-align:center;\">\n<strong>\ud83d\udd12 \u0160ifrovan\u00e9 platby<\/strong> \u00b7 <strong>\ud83d\udcb3 Ov\u011b\u0159en\u00fd platebn\u00ed procesor<\/strong> \u00b7 <strong>\ud83d\ude9a Doprava do cel\u00e9ho sv\u011bta<\/strong> \u00b7 <strong>\u2b50 4,9\/5 od 1 400+ z\u00e1kazn\u00edk\u016f<\/strong>\n<\/div>\n<h2 class=\"wp-block-heading\">What Is Anaridex?<\/h2>\n<p>Anaridex is an oral tablet from Cipla containing <strong>anastrozole 1 mg<\/strong>. Anastrozole is a third-generation, non-steroidal, selective aromatase inhibitor used for adjuvant and metastatic treatment of <strong>hormone-receptor-positive (HR+) breast cancer in postmenopausal women<\/strong>. Originally developed by AstraZeneca (brand name Arimidex), anastrozole is now a generic standard of care. It is one of the three most-prescribed aromatase inhibitors worldwide alongside <a href=\"https:\/\/medsbase.com\/cs\/xtane\/\">exemestane<\/a> a <a href=\"https:\/\/medsbase.com\/cs\/letroheal\/\">letrozole<\/a>.<\/p>\n<h2 class=\"wp-block-heading\">How Does Anaridex Work?<\/h2>\n<p>In postmenopausal women, ovarian oestrogen production has stopped &mdash; circulating oestrogen comes almost entirely from peripheral conversion of adrenal and gonadal androgens (androstenedione, testosterone) by the enzyme <strong>aromatase<\/strong> in fat, muscle, liver and breast tissue. Anastrozole reversibly inhibits aromatase, suppressing peripheral oestrogen synthesis by approximately <strong>95%<\/strong> within 24&ndash;48 hours.<\/p>\n<ul>\n<li><strong>Selective non-steroidal aromatase inhibitor<\/strong> &mdash; competes with androgen substrate at the aromatase active site without binding the oestrogen receptor itself.<\/li>\n<li><strong>Postmenopausal-only mechanism<\/strong> &mdash; in premenopausal women, the hypothalamic-pituitary-ovarian axis compensates by raising LH\/FSH and increasing ovarian aromatase, defeating the suppression. <strong>Anastrozole is ineffective in premenopausal women.<\/strong><\/li>\n<li><strong>Reversible binding<\/strong> &mdash; effect ends within 7&ndash;10 days of discontinuation as new aromatase enzyme is synthesised.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Pou\u017eit\u00ed a indikace<\/h2>\n<ul>\n<li><strong>How long do I stay on Keytruda?<\/strong> for early HR+ breast cancer in postmenopausal women, typically for 5 years (extended to 10 years in higher-risk disease)<\/li>\n<li><strong>First-line metastatic HR+ breast cancer<\/strong> in postmenopausal women, often combined with a CDK4\/6 inhibitor (palbociclib, ribociclib, abemaciclib)<\/li>\n<li><strong>Sequential therapy<\/strong> after 2&ndash;3 years of <a href=\"https:\/\/medsbase.com\/cs\/tamilong\/\">tamoxifen<\/a>, switching to an AI for completion of 5&ndash;10 years total endocrine therapy<\/li>\n<li><strong>Mimo indikaci:<\/strong> ovulation induction in fertility (specialist use), gynaecomastia in men on testosterone (specialist), male breast cancer (rare)<\/li>\n<\/ul>\n<p>Anaridex is <strong>ne<\/strong> indicated for: premenopausal women (use tamoxifen, or AI + ovarian suppression under specialist guidance), HR-negative breast cancer (no benefit), or non-cancer cosmetic indications.<\/p>\n<h2 class=\"wp-block-heading\">Anaridex Dosage and How to Take<\/h2>\n<p>Standardn\u00ed d\u00e1vka: <strong>1 mg jednou denn\u011b<\/strong>. Typical course length:<\/p>\n<ul>\n<li><strong>Adjuvant breast cancer:<\/strong> 5 years (10 years in high-risk node-positive disease, per ATLAS \/ aTTom data extrapolated to AIs)<\/li>\n<li><strong>Metastatic breast cancer:<\/strong> until disease progression or unacceptable toxicity<\/li>\n<\/ul>\n<h3 class=\"wp-block-heading\">How to Take Anaridex Properly<\/h3>\n<ol>\n<li><strong>Take one tablet once daily<\/strong> at approximately the same time each day. Morning or evening &mdash; the half-life (~50 hours) means timing has minimal effect on steady-state levels.<\/li>\n<li><strong>S j\u00eddlem nebo bez j\u00eddla.<\/strong><\/li>\n<li><strong>Polykejte cel\u00e9 s vodou.<\/strong><\/li>\n<li><strong>Povinn\u00e9 monitorov\u00e1n\u00ed:<\/strong> baseline DEXA bone-density scan, repeat every 2 years. Annual cholesterol panel. Lipid management as needed.<\/li>\n<li><strong>Bone protection:<\/strong> calcium 1,000&ndash;1,200 mg\/day + vitamin D 800&ndash;2,000 IU\/day. If osteopenia at baseline or develops, add a bisphosphonate (zoledronic acid IV every 6 months) or denosumab (60 mg SC every 6 months) as standard of care.<\/li>\n<li><strong>Joint pain management:<\/strong> regular weight-bearing exercise reduces arthralgia. Paracetamol or NSAIDs for symptomatic relief. Switching to <a href=\"https:\/\/medsbase.com\/cs\/letroheal\/\">letrozole<\/a> nebo <a href=\"https:\/\/medsbase.com\/cs\/xtane\/\">exemestane<\/a> sometimes helps if anastrozole arthralgia is intolerable.<\/li>\n<li><strong>Nep\u0159eru\u0161ujte l\u00e9\u010dbu bez pokyn\u016f onkologa.<\/strong> Discontinuation before completion of the planned course significantly increases recurrence risk.<\/li>\n<li><strong>Vynechan\u00e1 d\u00e1vka:<\/strong> if remembered same day, take it. If next day, skip and resume normally &mdash; do not double-dose.<\/li>\n<\/ol>\n<h2 class=\"wp-block-heading\">Side Effects of Anaridex<\/h2>\n<p><strong>Common (oestrogen-deprivation symptoms):<\/strong><\/p>\n<ul>\n<li>Hot flushes and night sweats (35&ndash;40%)<\/li>\n<li>Arthralgia (joint pain, stiffness, especially morning) &mdash; 30% of patients; main cause of discontinuation<\/li>\n<li>Myalgia (muscle aches)<\/li>\n<li>Vaginal dryness, dyspareunia<\/li>\n<li>Mood changes, low energy<\/li>\n<li>Hair thinning<\/li>\n<li>M\u00edrn\u00e1 nevolnost<\/li>\n<\/ul>\n<p><strong>Important long-term:<\/strong><\/p>\n<ul>\n<li><strong>Accelerated bone-density loss<\/strong> &mdash; fracture risk increased ~30% versus tamoxifen. Mandatory DEXA monitoring and bone-protection.<\/li>\n<li>Hyperlipidaemia (small increase in total cholesterol and LDL)<\/li>\n<li>Carpal tunnel syndrome<\/li>\n<\/ul>\n<p><strong>Less common but seek review:<\/strong><\/p>\n<ul>\n<li>Ischaemic cardiac events (small absolute increase, mainly in patients with prior cardiac disease)<\/li>\n<li>Hepatotoxicity (mild LFT rises common; severe rare)<\/li>\n<li>Endometrial cancer signal &mdash; lower than with tamoxifen, slightly higher than placebo<\/li>\n<li>Severe hypersensitivity (rare)<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Varov\u00e1n\u00ed a opat\u0159en\u00ed<\/h2>\n<ul>\n<li><strong>Pregnancy: ABSOLUTE CONTRAINDICATION.<\/strong> Anastrozole is teratogenic in animal models. Postmenopausal patients are usually past childbearing potential, but perimenopausal patients require contraception.<\/li>\n<li><strong>Premenopauz\u00e1ln\u00ed \u017eeny:<\/strong> ineffective unless combined with ovarian suppression (GnRH agonist) under specialist oncologist supervision. Default to <a href=\"https:\/\/medsbase.com\/cs\/tamilong\/\">tamoxifen<\/a> in premenopausal HR+ breast cancer.<\/li>\n<li><strong>Bone health:<\/strong> baseline DEXA before starting; repeat every 2 years. Calcium + vitamin D supplementation. Consider bisphosphonate or denosumab if osteopenia.<\/li>\n<li><strong>Kardiovaskul\u00e1rn\u00ed:<\/strong> small increase in ischaemic cardiac events versus tamoxifen. Address modifiable risk factors. Monitor lipids annually.<\/li>\n<li><strong>T\u011b\u017ek\u00e9 po\u0161kozen\u00ed jater:<\/strong> caution &mdash; limited data.<\/li>\n<li><strong>Concurrent oestrogen therapy<\/strong> (oestrogen-containing HRT or vaginal oestrogen): avoid &mdash; defeats the purpose of treatment.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Interakce s l\u00e9\u010divy<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Kombinujte s<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u00da\u010dinek<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Co d\u011blat<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Oestrogen-containing HRT or vaginal oestrogen<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Defeats anastrozole&#39;s mechanism &mdash; treatment fails<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Avoid all systemic and high-dose vaginal oestrogen. Use non-hormonal vaginal moisturisers. Specialist for low-dose vaginal oestriol if symptoms intolerable.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Tamoxifen<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Tamoxifen reduces anastrozole levels &mdash; do not combine<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Use sequentially, not concurrently.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Bisphosphonates (zoledronic acid, alendronate) or denosumab<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Synergistic bone-protection effect &mdash; standard combination<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Add when osteopenia develops on AI therapy.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Strong CYP3A4 inhibitors \/ inducers<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Modest effect on anastrozole levels &mdash; clinical significance unclear<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">No routine dose adjustment.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">CDK4\/6 inhibitors (palbociclib, ribociclib, abemaciclib)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Standard combination for first-line metastatic HR+ breast cancer<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Specialist oncology prescribing.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 class=\"wp-block-heading\">Pokyny k uchov\u00e1v\u00e1n\u00ed<\/h2>\n<ul>\n<li>Skladujte p\u0159i pokojov\u00e9 teplot\u011b, <strong>15\u201325\u00b0C<\/strong>. Uchov\u00e1vejte v p\u016fvodn\u00edm blistru.<\/li>\n<li>Uchov\u00e1vejte mimo dosah d\u011bt\u00ed a dom\u00e1c\u00edch zv\u00ed\u0159at.<\/li>\n<li>Nepou\u017eit\u00e9 tablety vra\u0165te do l\u00e9k\u00e1rny k likvidaci.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Souvisej\u00edc\u00ed alternativy na MedsBase<\/h2>\n<p>Dal\u0161\u00ed onkologick\u00e9 l\u00e9ky skladem vedle tohoto produktu:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/xtane\/\"><strong>Xtane (exemestan 25 mg)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/fempro\/\"><strong>Fempro (letrozol 2,5 mg)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/letroheal\/\"><strong>Letroheal (letrozol 2,5 mg)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/tamilong\/\"><strong>Tamilong (tamoxifen 10 \/ 20 mg)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/tamodex\/\"><strong>Tamodex (tamoxifen 10 \/ 20 mg)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/tamoxilon\/\"><strong>Tamoxilon (tamoxifen 10 \/ 20 mg)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/cytotam\/\"><strong>Cytotam (tamoxifen 10 \/ 20 mg)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/caditam\/\"><strong>Caditam (tamoxifen 20 mg)<\/strong><\/a><\/li>\n<\/ul>\n<p><a href=\"https:\/\/medsbase.com\/cs\/anti-cancer-medication\/\">Prohl\u00e9dn\u011bte v\u0161echny protin\u00e1dorov\u00e9 l\u00e9ky \u2192<\/a><\/p>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3 class=\"wp-block-heading\">Why is Anaridex only used in postmenopausal women?<\/h3>\n<p>In premenopausal women, the hypothalamic-pituitary axis responds to falling oestrogen by raising LH\/FSH and increasing ovarian aromatase, defeating the suppression. Anastrozole is therefore <strong>ineffective in premenopausal women<\/strong> as monotherapy. The standard endocrine therapy in premenopausal HR+ breast cancer is <a href=\"https:\/\/medsbase.com\/cs\/tamilong\/\">tamoxifen<\/a>; in higher-risk premenopausal patients, AI + GnRH agonist (ovarian suppression) is sometimes used under specialist supervision.<\/p>\n<h3 class=\"wp-block-heading\">How long do I take Anaridex for?<\/h3>\n<p>Standard adjuvant duration is <strong>5 let<\/strong>. For higher-risk node-positive disease, extended therapy to <strong>7&ndash;10 years<\/strong> is increasingly recommended (extrapolated from ATLAS and aTTom tamoxifen data and AI extension trials such as MA.17R). For metastatic disease, anastrozole continues until progression or intolerable toxicity.<\/p>\n<h3 class=\"wp-block-heading\">How do I manage joint pain on Anaridex?<\/h3>\n<p>Aromatase inhibitor arthralgia affects ~30% of patients and is the main reason for premature discontinuation. First-line measures: regular weight-bearing exercise (yoga, walking, swimming), vitamin D 1,000&ndash;2,000 IU\/day, paracetamol or short courses of NSAIDs, weight management. If intolerable, switching to <a href=\"https:\/\/medsbase.com\/cs\/letroheal\/\">letrozole<\/a> nebo <a href=\"https:\/\/medsbase.com\/cs\/xtane\/\">exemestane<\/a> sometimes helps &mdash; about 30% of patients tolerate one AI but not another.<\/p>\n<h3 class=\"wp-block-heading\">Will Anaridex weaken my bones?<\/h3>\n<p>Yes &mdash; aromatase inhibitors accelerate bone-density loss with about <strong>30% increased fracture risk<\/strong> versus tamoxifen. Mandatory baseline DEXA scan, repeat every 2 years. Calcium + vitamin D supplementation is standard. If osteopenia develops, add a bisphosphonate (zoledronic acid IV every 6 months) or denosumab (60 mg SC every 6 months) &mdash; this is now standard of care and should be discussed with the oncologist.<\/p>\n<h3 class=\"wp-block-heading\">Can I use vaginal oestrogen for dryness while on Anaridex?<\/h3>\n<p>Generally not recommended &mdash; even low-dose vaginal oestrogen produces measurable systemic absorption that can defeat AI therapy. First-line: non-hormonal vaginal moisturisers (Replens, hyaluronic acid gels) and water-based lubricants. If symptoms are intolerable, a specialist may consider very low-dose vaginal oestriol on an individual risk-benefit basis (vaginal oestriol has lower systemic absorption than oestradiol).<\/p>\n<h3 class=\"wp-block-heading\">Anaridex vs tamoxifen vs letrozole vs exemestane &mdash; which is right for me?<\/h3>\n<p>This is an oncologist decision based on your menopausal status, tumour biology, and side-effect profile. Broad pattern: <strong>premenopausal HR+<\/strong> \u2192 <a href=\"https:\/\/medsbase.com\/cs\/tamilong\/\">tamoxifen<\/a> first-line. <strong>Postmenopausal HR+<\/strong> &rarr; AI (anastrozole \/ letrozole \/ exemestane) first-line, with switch to tamoxifen as 2nd-line if AI intolerance. The three AIs have similar efficacy. Anastrozole and letrozole are non-steroidal; exemestane is steroidal and structurally distinct. Switching between AIs is reasonable for intolerable side effects.<\/p>\n<h3 class=\"wp-block-heading\">Is Anaridex safe in pregnancy?<\/h3>\n<p>Absolutely not. Anastrozole is contraindicated in pregnancy and breastfeeding. Postmenopausal patients are usually past childbearing potential, but perimenopausal patients (chemotherapy-induced amenorrhoea may not be permanent) need reliable non-hormonal contraception throughout treatment.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Anaridex with my heart medications?<\/h3>\n<p>Anastrozole has minimal direct interactions with cardiovascular medications. The relevant clinical concern is the <strong>small increased risk of ischaemic cardiac events<\/strong> on AI therapy versus tamoxifen, particularly in patients with established cardiac disease. Optimise modifiable cardiac risk factors (statins for hyperlipidaemia, BP control, smoking cessation, exercise) and discuss any chest pain promptly.<\/p>\n<h3 class=\"wp-block-heading\">What happens if I stop Anaridex early?<\/h3>\n<p>Stopping adjuvant aromatase inhibitor therapy before completion of the planned 5&ndash;10 years course significantly increases breast cancer recurrence risk. Real-world data show that fewer than 50% of patients complete the full 5 years &mdash; usually because of arthralgia and quality-of-life impact. Always discuss intolerable side effects with your oncologist before stopping &mdash; switching AI, dose modifications, supportive care, and acupuncture for arthralgia are all options before discontinuation.<\/p>\n<p><!-- medsbase-why-order --><\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Ka\u017ed\u00e1 \u0161ar\u017ee je dod\u00e1v\u00e1na od <strong>v\u00fdrobce certifikovan\u00e9ho WHO-GMP<\/strong>. Objedn\u00e1vky jsou expedov\u00e1ny v nen\u00e1padn\u00fdch obalech bez loga od na\u0161ich partnersk\u00fdch sklad\u016f a jsou pokryty na\u0161\u00ed <a href=\"\/cs\/medsbase-re-shipment-assurance-policy\/\">Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/a>: pokud z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, za\u0161leme zdarma n\u00e1hradn\u00ed z\u00e1silku, bez dotaz\u016f.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Souvisej\u00edc\u00ed protin\u00e1dorov\u00e9 l\u00e9ky<\/h3>\n<p>Dal\u0161\u00ed onkologick\u00e9 l\u00e9ky skladem vedle tohoto produktu:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/xtane\/\">Xtane (exemestan 25 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/letroheal\/\">Letroheal (letrozol 2,5 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/fempro\/\">Fempro (letrozol 2,5 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/tamilong\/\">Tamilong (tamoxifen 10\/20 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/tamodex\/\">Tamodex (tamoxifen 10\/20 mg)<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Sni\u017euje riziko rakoviny prsu<br \/>\n\u2705 Inhibits estrogen production<br \/>\n\u2705 Treats hormone receptor-positive<br \/>\n\u2705 Slows cancer progression<br \/>\n\u2705 Manages postmenopausal symptoms<\/p>\n<p><span style=\"color: #000000\">Anaridex contains <strong>cardiovascular risk<\/strong><\/span><\/p>","protected":false},"featured_media":55287,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[3595,3141,3223],"product_tag":[3899,3900],"class_list":{"0":"post-55286","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-cancer-medication","7":"product_cat-category-overview","8":"product_cat-chronic-conditions","9":"product_tag-anaridex","10":"product_tag-anastrozole","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/55286","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=55286"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/55287"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=55286"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=55286"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=55286"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=55286"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}