{"id":55590,"date":"2024-02-07T05:32:09","date_gmt":"2024-02-07T05:32:09","guid":{"rendered":"https:\/\/medsname.com\/atomoxet\/"},"modified":"2026-04-30T10:24:46","modified_gmt":"2026-04-30T10:24:46","slug":"atomoxet","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/atomoxet\/","title":{"rendered":"Atomoxet"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"background:#fff8d6;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<h3 style=\"margin-top:0;\">\u26a1 Rychl\u00e1 odpov\u011b\u010f<\/h3>\n<p style=\"margin-bottom:0;\">Atomoxet (Atomoxetine 10 \/ 18 \/ 25 \/ 40 \/ 60 \/ 80 mg) is a selective noradrenaline reuptake inhibitor for ADHD in children, adolescents, and adults. Non-stimulant \u2014 no abuse potential, no controlled-substance scheduling. Useful when stimulants are unsuitable, ineffective, or contraindicated.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Co z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Atomoxet at MedsBase is supplied directly from a WHO-GMP certified manufacturer in plain, discreet packaging. Every order is covered by our <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\">Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/a> \u2014 20pracovn\u00edchdenn\u00ed lh\u016fta pro doru\u010den\u00ed, nebo v\u00e1m z\u00e1silku zdarma p\u0159epo\u0161leme \u2014 a oprav\u0148uje v\u00e1s k \u00fa\u010dasti v na\u0161em <a href=\"https:\/\/medsbase.com\/cs\/loyalty-points\/\">v\u011brnostn\u00edm programu<\/a>. Dod\u00e1v\u00e1me do v\u011bt\u0161iny zem\u00ed po cel\u00e9m sv\u011bt\u011b.<\/p>\n<h2>What Atomoxet is and how it works<\/h2>\n<p>Atomoxet is a 10 \/ 18 \/ 25 \/ 40 \/ 60 \/ 80 mg atomoxetine capsule supplied by Intas. Atomoxetine selectively inhibits the noradrenaline reuptake transporter (NET), increasing synaptic noradrenaline and \u2014 indirectly via cortical NA-DA crosstalk \u2014 frontal-cortex dopamine, without affecting striatal dopamine. The latter is what differentiates atomoxetine from stimulants: no euphoria, no abuse potential, no controlled-substance scheduling.<\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<strong>Slow onset \u2014 not a same-day medication<\/strong><\/p>\n<p style=\"margin-bottom:0;\">Stimulants work within 30\u201360 minutes of the first dose. Atomoxetine takes 2\u20134 weeks for initial response and 8\u201312 weeks for full effect. Patients (and parents) expecting stimulant-like immediate change will be disappointed and discontinue. Set the expectation at initiation.<\/p>\n<\/div>\n<h2>Indikace a d\u00e1vkov\u00e1n\u00ed<\/h2>\n<table>\n<thead>\n<tr>\n<th>Pacient<\/th>\n<th>Po\u010d\u00e1te\u010dn\u00ed d\u00e1vka<\/th>\n<th>C\u00edlov\u00e1 d\u00e1vka<\/th>\n<th>Maxim\u00e1ln\u00ed d\u00e1vka<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Children &amp; adolescents \u2264 70 kg<\/td>\n<td>0.5 mg\/kg\/day \u00d7 3 d<\/td>\n<td>1.2 mg\/kg\/day<\/td>\n<td>1.4 mg\/kg or 100 mg<\/td>\n<\/tr>\n<tr>\n<td>Children &amp; adolescents &gt; 70 kg<\/td>\n<td>40 mg OD \u00d7 3 d<\/td>\n<td>80 mg OD<\/td>\n<td>100 mg OD<\/td>\n<\/tr>\n<tr>\n<td>Dosp\u011bl\u00ed<\/td>\n<td>40 mg OD \u00d7 7 d<\/td>\n<td>80 mg OD<\/td>\n<td>100 mg<\/td>\n<\/tr>\n<tr>\n<td>Strong CYP2D6 inhibitor \/ poor metaboliser<\/td>\n<td>0.5 mg\/kg or 40 mg<\/td>\n<td>0.5 \u00d7 normal target<\/td>\n<td>by tolerability<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Can be given once daily morning or split BID (morning + late afternoon \u2014 avoid evening because of insomnia).<\/p>\n<h2>D\u016fle\u017eit\u00e9 bezpe\u010dnostn\u00ed aspekty<\/h2>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<strong>Suicidality black-box (paediatric)<\/strong><\/p>\n<p style=\"margin-bottom:0;\">Atomoxetine carries an FDA black-box warning for increased suicidal ideation in children and adolescents, particularly in the first month and at dose changes. Monitor closely for behaviour change in paediatric patients on initiation.<\/p>\n<\/div>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<strong>Hepatotoxicity \u2014 rare<\/strong><\/p>\n<p style=\"margin-bottom:0;\">Rare cases of severe hepatic injury have been reported. Stop immediately if jaundice, dark urine, RUQ pain, fatigue, or unexplained nausea appear. Do not restart after definite hepatic injury.<\/p>\n<\/div>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<strong>Kardiovaskul\u00e1rn\u00ed<\/strong><\/p>\n<p style=\"margin-bottom:0;\">Atomoxetine produces small mean increases in BP (+2 mmHg) and HR (+5 bpm). Greater rises occasionally seen in adults. Check BP and HR at baseline, at each dose change, and at follow-up. Avoid in serious cardiac structural abnormality, severe cardiovascular disease, or pheochromocytoma.<\/p>\n<\/div>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<strong>Growth (paediatric)<\/strong><\/p>\n<p style=\"margin-bottom:0;\">Mild reductions in growth velocity reported in children on atomoxetine \u2014 usually catch up over time. Plot height and weight at every visit.<\/p>\n<\/div>\n<h2>\u010cast\u00e9 ne\u017e\u00e1douc\u00ed \u00fa\u010dinky<\/h2>\n<ul>\n<li><strong>Gastrointestin\u00e1ln\u00ed:<\/strong> nausea, vomiting, abdominal pain, decreased appetite, dyspepsia \u2014 most prominent first 1\u20132 weeks.<\/li>\n<li><strong>CNS:<\/strong> headache, somnolence or insomnia, dizziness, mood lability.<\/li>\n<li><strong>Kardiovaskul\u00e1rn\u00ed:<\/strong> small BP and HR rise.<\/li>\n<li><strong>Sexual:<\/strong> erectile difficulty, ejaculation disorders in adult men.<\/li>\n<li><strong>GU:<\/strong> urinary hesitancy.<\/li>\n<li><strong>V\u00fdznamn\u00e9 absence:<\/strong> no abuse potential, no euphoria, no rebound, no tics. Useful when stimulants worsen tics or anxiety.<\/li>\n<\/ul>\n<h2>Interakce l\u00e9k\u016f<\/h2>\n<ul>\n<li><strong>MAOI<\/strong> \u2014 absolute contraindication; 14-day washout each direction.<\/li>\n<li><strong>Strong CYP2D6 inhibitors<\/strong> (paroxetine, fluoxetine, bupropion, quinidine) \u2014 significantly raise atomoxetine levels; halve dose or switch.<\/li>\n<li><strong>Pressor agents \/ other sympathomimetics<\/strong> \u2014 additive cardiovascular effects.<\/li>\n<li><strong>Dal\u0161\u00ed l\u00e9ky prodlu\u017euj\u00edc\u00ed QT interval<\/strong> \u2014 small additive risk.<\/li>\n<\/ul>\n<h2>T\u011bhotenstv\u00ed, kojen\u00ed, pediatrie<\/h2>\n<p>Pregnancy category C \u2014 limited data. Breastfeeding: insufficient data. Paediatric: licensed from age 6, with the suicidality black-box.<\/p>\n<h2>Skladov\u00e1n\u00ed<\/h2>\n<p>Skladujte p\u0159i 15\u201330 \u00b0C v p\u016fvodn\u00edm obalu.<\/p>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3>How is Atomoxet different from a stimulant?<\/h3>\n<p>Atomoxetine is non-stimulant, non-controlled, with no abuse potential and no euphoria. The trade-off: slower onset (weeks rather than minutes), generally smaller effect size in trials, and a different side-effect profile (more GI, less appetite suppression, less insomnia, no rebound).<\/p>\n<h3>How long until Atomoxet works?<\/h3>\n<p>Some response by week 2\u20134; full effect at 8\u201312 weeks. If there is no response after 12 weeks at 1.2\u20131.4 mg\/kg or 80\u2013100 mg, switch.<\/p>\n<h3>Can Atomoxet be used with a stimulant?<\/h3>\n<p>Yes \u2014 combination is described under specialist supervision when monotherapy is partial. Cardiovascular monitoring is more important.<\/p>\n<h3>Why doesn&rsquo;t Atomoxet need refrigeration or controlled-substance dispensing?<\/h3>\n<p>Atomoxetine is not a controlled substance in any major jurisdiction \u2014 no scheduling, no special prescription, no pharmacy storage requirements. This makes it convenient for travel and for patients in workplaces with drug-testing regimes (it does not produce stimulant metabolites on standard urine screens).<\/p>\n<h3>Will Atomoxet affect appetite or weight?<\/h3>\n<p>Mild appetite suppression \u2014 much less than stimulants. Most adults and children maintain normal weight; mild weight loss in some.<\/p>\n<h3>Can Atomoxet be taken in the morning only?<\/h3>\n<p>Yes \u2014 once-daily morning dosing is the most common pattern. The pharmacokinetic half-life is approximately 5 hours but the clinical effect persists much longer because of receptor-level changes. Some patients prefer split BID dosing for symptom coverage; clinician choice.<\/p>\n<h3>Can Atomoxet cause sexual side effects?<\/h3>\n<p>Yes \u2014 particularly in adult men, ejaculation disorders and erectile dysfunction are reported in 5\u201310%. Less common than SSRIs.<\/p>\n<h3>Can Atomoxet be used in adults with anxiety?<\/h3>\n<p>Useful when ADHD coexists with anxiety \u2014 atomoxetine&rsquo;s noradrenergic action can be either anxiolytic (long-term) or anxiogenic (initial weeks). Stimulants tend to worsen anxiety, atomoxetine often does not.<\/p>\n<h3>Can I stop Atomoxet abruptly?<\/h3>\n<p>Yes \u2014 atomoxetine has minimal withdrawal because of its short half-life. Most patients stop directly without taper.<\/p>\n<h3>Will Atomoxet show up on drug tests?<\/h3>\n<p>No \u2014 atomoxetine does not produce stimulant metabolites and does not show on standard amphetamine or methylphenidate workplace screens.<\/p>\n<h2>Dal\u0161\u00ed l\u00e9ky na du\u0161evn\u00ed zdrav\u00ed<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/agoprex\/\">Agoprex (Agomelatine \u2014 adult comorbid depression)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/lexaheal\/\">Lexaheal (Escitalopram \u2014 comorbid anxiety)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/bupron-xl\/\">Bupron XL (Bupropion \u2014 NDRI; off-label ADHD adjunct)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/flunil\/\">Flunil (Fluoxetine SSRI)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/mirtaz\/\">Mirtaz (Mirtazapine NaSSA)<\/a><\/li>\n<\/ul>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:0.9em;\">\n<strong>Zdravotn\u00ed prohl\u00e1\u0161en\u00ed.<\/strong> Tato str\u00e1nka m\u00e1 vzd\u011bl\u00e1vac\u00ed charakter a nenahrazuje individu\u00e1ln\u00ed l\u00e9ka\u0159skou radu. Farmakoterapie du\u0161evn\u00edho zdrav\u00ed by m\u011bla b\u00fdt zah\u00e1jena, monitorov\u00e1na a upravov\u00e1na pod dohledem kvalifikovan\u00e9ho l\u00e9ka\u0159e. Pokud vy nebo n\u011bkdo, koho zn\u00e1te, pro\u017e\u00edv\u00e1 sebevra\u017eednou krizi, okam\u017eit\u011b kontaktujte m\u00edstn\u00ed z\u00e1chrann\u00e9 slu\u017eby nebo volejte linku prevence sebevra\u017ed ve va\u0161\u00ed zemi (USA\/Kanada: 988; UK: Samaritans 116 123; mezin\u00e1rodn\u00ed seznam: <a href=\"https:\/\/findahelpline.com\/\" rel=\"nofollow noopener\" target=\"_blank\">findahelpline.com<\/a>).\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Atomoxet (Atomoxetine 10\u201380 mg) \u2014 selective NA reuptake inhibitor (NRI) for ADHD in children, adolescents and adults. non-stimulant, non-controlled \u2014 slow onset 2\u20134 weeks.<\/p>","protected":false},"featured_media":55591,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3342,3906],"product_tag":[3951,3952],"class_list":{"0":"post-55590","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-general-health","8":"product_cat-mental-health-and-psychiatric-medications","9":"product_tag-atomoxet","10":"product_tag-atomoxetine","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/55590","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=55590"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/55591"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=55590"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=55590"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=55590"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=55590"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}