{"id":55834,"date":"2024-02-07T05:42:30","date_gmt":"2024-02-07T05:42:30","guid":{"rendered":"https:\/\/medsname.com\/betnovate-cream\/"},"modified":"2026-05-07T05:29:00","modified_gmt":"2026-05-07T05:29:00","slug":"betnovate-cream","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/betnovate-cream\/","title":{"rendered":"Betnovate kr\u00e9m"},"content":{"rendered":"

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\u26a1 Rychl\u00e1 odpov\u011b\u010f \u2014 Co je Betnovate kr\u00e9m?<\/h3>\n

Betnovate kr\u00e9m<\/strong> obsahuje betamethasonvaler\u00e1t 0,1%<\/strong> jako topick\u00fd kr\u00e9m od spole\u010dnosti GlaxoSmithKline \u2014 siln\u00fd topick\u00fd kortikosteroid (t\u0159\u00edda III ve Velk\u00e9 Brit\u00e1nii \/ t\u0159\u00edda III-II v USA)<\/strong>, jeden z nej\u010dast\u011bji p\u0159edepisovan\u00fdch topick\u00fdch steroid\u016f na sv\u011bt\u011b. Pou\u017e\u00edv\u00e1 se p\u0159i st\u0159edn\u011b t\u011b\u017ek\u00e9m a\u017e t\u011b\u017ek\u00e9m ekz\u00e9mu, psori\u00e1ze vulgaris, kontaktn\u00ed dermatitid\u011b, lichen planus, discoidn\u00edm lupusu, seboroick\u00e9 dermatitid\u011b, lichen simplex chronicus<\/strong>, a dal\u0161\u00edch steroid-responsivn\u00edch z\u00e1n\u011btliv\u00fdch dermat\u00f3z\u00e1ch na t\u011ble. Aplikujte tenkou vrstvu jednou nebo dvakr\u00e1t denn\u011b<\/strong> \u2014 jednou denn\u011b posta\u010duje u v\u011bt\u0161iny vzplanut\u00ed a sni\u017euje kumulativn\u00ed steroidn\u00ed z\u00e1t\u011b\u017e. Maxim\u00e1ln\u00ed nep\u0159etr\u017eit\u00e1 l\u00e9\u010dba je 2\u20134 t\u00fddny na t\u011ble<\/strong>; NEPOU\u017d\u00cdVEJTE na obli\u010dej, v\u00ed\u010dka, podpa\u017e\u00ed, t\u0159\u00edsla nebo pod okluz\u00ed bez specifick\u00e9ho l\u00e9ka\u0159sk\u00e9ho doporu\u010den\u00ed. Betnovate je zna\u010dka, kter\u00e1 definovala t\u0159\u00eddu \u201csiln\u00fdch topick\u00fdch steroid\u016f\u201d ve Velk\u00e9 Brit\u00e1nii a zem\u00edch Commonwealthu od 60. let 20. stolet\u00ed; farmakologie se nezm\u011bnila \u2014 pouze generika, kter\u00e1 n\u00e1sledovala.<\/p>\n<\/div>\n

\nCo z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n

\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n

Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n

Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n

Co je Betnovate kr\u00e9m?<\/h2>\n

Betnovate kr\u00e9m je topick\u00fd betamethasonvaler\u00e1t 0,1%<\/strong> kr\u00e9m od spole\u010dnosti GlaxoSmithKline dod\u00e1van\u00fd v tub\u011b o hmotnosti 20 g. Betamethason valer\u00e1t je syntetick\u00fd fluorovan\u00fd glukokortikoid \u2014 jeden z nejpou\u017e\u00edvan\u011bj\u0161\u00edch siln\u00fdch topick\u00fdch kortikosteroid\u016f na sv\u011bt\u011b, poprv\u00e9 uveden\u00fd spole\u010dnost\u00ed GSK pod p\u016fvodn\u00ed zna\u010dkou Betnovate v roce 1963. Ekvivalentn\u00ed \u00fa\u010dinnost jako mometason 0,1%<\/a> a fluticasone propionate 0,05 %<\/a> (v\u0161echny t\u0159\u00eddy III ve Velk\u00e9 Brit\u00e1nii).<\/p>\n

Dod\u00e1v\u00e1 se tak\u00e9 v souvisej\u00edc\u00edch formulac\u00edch GSK po cel\u00e9m sv\u011bt\u011b: Betnovate-RD (sn\u00ed\u017een\u00e1 s\u00edla 0,025% pro postupnou redukci), Betnovate-C (s antibakteri\u00e1ln\u00edm\/antifung\u00e1ln\u00edm klioquinolem), Betnovate-N (s antibakteri\u00e1ln\u00edm neomycinem), Betnovate Scalp Application (alkoholov\u00fd roztok pro psori\u00e1zu poko\u017eky hlavy a seboroickou dermatitidu).<\/p>\n

\u017deb\u0159\u00ed\u010dek \u00fa\u010dinnosti topick\u00fdch steroid\u016f \u2014 kde se Betnovate nach\u00e1z\u00ed<\/h2>\n\n\n\n\n\n\n\n\n
Britsk\u00e1 t\u0159\u00edda<\/th>\nAmerick\u00e1 t\u0159\u00edda<\/th>\nP\u0159\u00edklady<\/th>\n<\/tr>\n<\/thead>\n
I (m\u00edrn\u00fd)<\/td>\nVII-VI<\/td>\nHydrokortizon 0,5-1 %, desonid 0,05 % (Desowen)<\/strong><\/td>\n<\/tr>\n
II (st\u0159edn\u011b siln\u00fd)<\/td>\nV<\/td>\nKlobetason butyr\u00e1t, betamethason valer\u00e1t 0,025%<\/td>\n<\/tr>\n
III (siln\u00fd)<\/td>\nIII\u2013II<\/td>\nBetamethasonvaler\u00e1t 0,1 % (Betnovate<\/strong>), mometason 0,1 % (Elocon<\/a>, Momin<\/a>), flutikason (Flutivate<\/a>)<\/td>\n<\/tr>\n
IV (velmi siln\u00fd)<\/td>\nI<\/td>\nKlobetasolpropion\u00e1t 0,05 % (Tenovate<\/a>), halobetasolpropion\u00e1t 0,05 % (Halox<\/a>)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Betnovate (betamethasonvaler\u00e1t 0,1%) pat\u0159\u00ed do skupiny siln\u00fdch topick\u00fdch steroid\u016f \u2014 je z\u00e1kladn\u00edm l\u00e9kem pro l\u00e9\u010dbu st\u0159edn\u011b t\u011b\u017ek\u00e9ho a\u017e t\u011b\u017ek\u00e9ho atopick\u00e9ho ekz\u00e9mu a lo\u017eiskov\u00e9 psori\u00e1zy. Pou\u017e\u00edvejte nejni\u017e\u0161\u00ed \u00fa\u010dinnost, kter\u00e1 kontroluje stav, a p\u0159ejd\u011bte na slab\u0161\u00ed steroid nebo na steroid-\u0161et\u0159\u00edc\u00ed l\u00e9\u010dbu, jakmile je vzplanut\u00ed pod kontrolou.<\/p>\n

Jak Betnovate kr\u00e9m funguje<\/h2>\n

Betamethasonvaler\u00e1t se v\u00e1\u017ee na intracelul\u00e1rn\u00ed glukokortikoidn\u00ed receptory v keratinocytech, ko\u017en\u00edch fibroblastech a z\u00e1n\u011btliv\u00fdch bu\u0148k\u00e1ch. Aktivovan\u00fd receptor-DNA komplex potla\u010duje transkripci proz\u00e1n\u011btliv\u00fdch cytokin\u016f (IL-1, IL-2, IL-6, TNF-\u03b1), blokuje fosfolip\u00e1zu A2<\/sub> (sn\u00ed\u017een\u00edm produkce prostaglandin\u016f a leukotrien\u016f) a indukuje apopt\u00f3zu aktivovan\u00fdch T-lymfocyt\u016f v k\u016f\u017ei. Klinick\u00fdm v\u00fdsledkem je rychl\u00e1 a spolehliv\u00e1 kontrola z\u00e1n\u011btu, sv\u011bd\u011bn\u00ed, zarudnut\u00ed a \u0161upinat\u011bn\u00ed u ekz\u00e9mu a psori\u00e1zy.<\/p>\n

N\u00e1stup \u00fa\u010dinku: sv\u011bd\u011bn\u00ed a zarudnut\u00ed za\u010d\u00ednaj\u00ed ustupovat b\u011bhem 24-48 hodin; pln\u00fd \u00fa\u010dinek obvykle za 1-2 t\u00fddny u ekz\u00e9mu a za 2-4 t\u00fddny u psoriatick\u00fdch lo\u017eisek.<\/p>\n

Schv\u00e1len\u00e9 indikace<\/h2>\n