{"id":55867,"date":"2024-02-07T05:43:51","date_gmt":"2024-02-07T05:43:51","guid":{"rendered":"https:\/\/medsname.com\/alphagan-p-drop\/"},"modified":"2026-04-30T10:24:43","modified_gmt":"2026-04-30T10:24:43","slug":"alphagan-p-drop","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/alphagan-p-drop\/","title":{"rendered":"Alphagan P kapky"},"content":{"rendered":"

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\u26a1 Rychl\u00e1 odpov\u011b\u010f \u2014 Co jsou kapky Alphagan P?<\/h3>\n

Kapky Alphagan P obsahuj\u00ed brimonidin 0,15%, co\u017e je alfa-2 adrenergn\u00ed agonista, kter\u00fd sni\u017euje nitroo\u010dn\u00ed tlak p\u0159ibli\u017en\u011b o 20% sn\u00ed\u017een\u00edm tvorby komorov\u00e9 vody a zv\u00fd\u0161en\u00edm uveoskler\u00e1ln\u00edho odtoku. Aplikuje se t\u0159ikr\u00e1t denn\u011b. Opatrnost u d\u011bt\u00ed \u2014 vyvarujte se u v\u011bku < 2 roky (riziko apnoe).<\/p>\n<\/div>\n

Pro\u010d objedn\u00e1vat z MedsBase?<\/strong> Dod\u00e1v\u00e1no od v\u00fdrobce certifikovan\u00e9ho WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Doprava po cel\u00e9m sv\u011bt\u011b \u00b7 1 400+ ov\u011b\u0159en\u00fdch recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a><\/div>\n

\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n

Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n

Kapky Alphagan P jsou dod\u00e1v\u00e1ny od v\u00fdrobce certifikovan\u00e9ho WHO-GMP a expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v nen\u00e1padn\u00e9m balen\u00ed. Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00edm Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/a> \u2014 pokud nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me bez dal\u0161\u00edch n\u00e1klad\u016f. Podpo\u0159eno v\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdmi recenzemi z\u00e1kazn\u00edk\u016f.<\/p>\n

Co jsou kapky Alphagan P?<\/h2>\n

Alphagan P Drop vyr\u00e1b\u00ed spole\u010dnost Allergan a obsahuje brimonidin tartr\u00e1t 0,15% jako steriln\u00ed o\u010dn\u00ed roztok. Brimonidin je vysoce selektivn\u00ed agonista alfa-2 adrenergn\u00edch receptor\u016f pou\u017e\u00edvan\u00fd ke sn\u00ed\u017een\u00ed nitroo\u010dn\u00edho tlaku u otev\u0159en\u00e9ho \u00fahlu glaukomu a o\u010dn\u00ed hypertenze. M\u00e1 unik\u00e1tn\u00ed dvoj\u00ed mechanismus \u00fa\u010dinku \u2014 sni\u017euje tvorbu komorov\u00e9 vody A z\u00e1rove\u0148 zvy\u0161uje uveoskler\u00e1ln\u00ed odtok \u2014 a pat\u0159\u00ed mezi n\u011bkolik m\u00e1lo glaukomov\u00fdch kapek s mo\u017en\u00fdm neuroprotektivn\u00edm \u00fa\u010dinkem na gangliov\u00e9 bu\u0148ky s\u00edtnice, co\u017e nazna\u010duj\u00ed laboratorn\u00ed a klinick\u00e9 studie mal\u00fdch kohort.<\/p>\n

Jak to funguje<\/h2>\n

Brimonidin aktivuje alfa-2 receptory v \u0159asnat\u00e9m t\u011blese, sni\u017euje cAMP a t\u00edm produkci komorov\u00e9 vody. Z\u00e1rove\u0148 zvy\u0161uje uveoskler\u00e1ln\u00ed odtok. Pr\u016fm\u011brn\u00e9 sn\u00ed\u017een\u00ed nitroo\u010dn\u00edho tlaku je 18\u201322%. Formulace 0,15% (Alphagan P) vyu\u017e\u00edv\u00e1 konzerva\u010dn\u00ed syst\u00e9m Purite, kter\u00fd se v slzn\u00e9m filmu rozkl\u00e1d\u00e1 na vodu, kysl\u00edk a chloridov\u00e9 ionty, co\u017e je \u0161etrn\u011bj\u0161\u00ed ne\u017e benzalkoniumchlorid pro dlouhodob\u00e9 u\u017e\u00edv\u00e1n\u00ed.<\/p>\n

Indikace & D\u00e1vkov\u00e1n\u00ed<\/h2>\n\n\n\n\n\n\n\n
Indikace<\/th>\nD\u00e1vka<\/th>\n<\/tr>\n<\/thead>\n
Otev\u0159en\u00fd \u00fahel glaukomu \/ o\u010dn\u00ed hypertenze<\/td>\n1 kapka do posti\u017een\u00e9ho oka(ou) t\u0159ikr\u00e1t denn\u011b (ka\u017ed\u00fdch 8 hodin)<\/td>\n<\/tr>\n
Dopl\u0148kov\u00e1 terapie<\/td>\nDvakr\u00e1t denn\u011b<\/td>\n<\/tr>\n
Profylaxe po laserov\u00fdch v\u00fdkonech (LPI, SLT) proti vzestupu nitroo\u010dn\u00edho tlaku<\/td>\n1 kapka p\u0159ed v\u00fdkonem a 1 kapka po v\u00fdkonu<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
D\u011btsk\u00e1 apnoe \u2014 vyvarujte se u d\u011bt\u00ed < 2 roky.<\/strong> Brimonidin snadno pronik\u00e1 hematoencefalickou bari\u00e9rou. U d\u011bt\u00ed mlad\u0161\u00edch 2 let i o\u010dn\u00ed brimonidin zp\u016fsobil \u017eivot ohro\u017euj\u00edc\u00ed \u00fatlum CNS s apnoe, bradykardi\u00ed a hypotenz\u00ed. Vyhn\u011bte se u\u017eit\u00ed u v\u011bku < 2; pou\u017e\u00edvejte s extr\u00e9mn\u00ed opatrnost\u00ed ve v\u011bku 2\u20136 let (pouze formulace Alphagan P 0,1%, pod dohledem rodi\u010d\u016f a s pozorov\u00e1n\u00edm).<\/div>\n

Vedlej\u0161\u00ed \u00fa\u010dinky<\/h2>\n

Lok\u00e1ln\u00ed (10\u201320%):<\/strong> konjunktiv\u00e1ln\u00ed hyper\u00e9mie, alergick\u00e1 konjunktivitida (obvykle se objevuje za 6\u201318 m\u011bs\u00edc\u016f \u2014 charakteristick\u00fd pozdn\u00ed n\u00e1stup), folikul\u00e1rn\u00ed konjunktivitida, sv\u011bd\u011bn\u00ed o\u010d\u00ed, pocit ciz\u00edho t\u011blesa, rozmazan\u00e9 vid\u011bn\u00ed.<\/p>\n

Syst\u00e9mov\u00e9:<\/strong> sucho v \u00fastech, \u00fanava, ospalost, bolest hlavy, hypotenze. U d\u011bt\u00ed (zejm\u00e9na pod 6 let) se m\u016f\u017ee objevit somnolence a bradykardie.<\/p>\n

Varov\u00e1n\u00ed a kontraindikace<\/h2>\n