{"id":55867,"date":"2024-02-07T05:43:51","date_gmt":"2024-02-07T05:43:51","guid":{"rendered":"https:\/\/medsname.com\/alphagan-p-drop\/"},"modified":"2026-04-30T10:24:43","modified_gmt":"2026-04-30T10:24:43","slug":"alphagan-p-drop","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/alphagan-p-drop\/","title":{"rendered":"Alphagan P kapky"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"background:#fffbe6;border-left:4px solid #f5a623;padding:14px 18px;margin:14px 0 22px;border-radius:6px;font-size:15px;line-height:1.55;\">\n<h3 style=\"margin:0 0 6px;font-size:17px;color:#8a6d3b;\">\u26a1 Quick Answer \u2014 What is Alphagan P Drop?<\/h3>\n<p style=\"margin:0;\">Alphagan P Drop is brimonidine 0.15%, an alpha-2 adrenergic agonist eye drop that lowers eye pressure ~20% by reducing aqueous production AND increasing uveoscleral outflow. Three times daily dosing. Caution in children \u2014 avoid in age &lt; 2 years (apnoea risk).<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f6f7fb;border:1px solid #e3e5ee;border-radius:8px;padding:14px 18px;margin:18px 0;font-size:14px;line-height:1.55;\"><strong style=\"color:#1f3661;\">Pro\u010d objedn\u00e1vat z MedsBase?<\/strong> Dod\u00e1v\u00e1no od v\u00fdrobce certifikovan\u00e9ho WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Doprava po cel\u00e9m sv\u011bt\u011b \u00b7 <a href=\"\/cs\/reviews\/\" rel=\"noopener\">1 400+ ov\u011b\u0159en\u00fdch recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Alphagan P Drop is sourced from a WHO-GMP certified manufacturer and shipped worldwide in plain, discreet packaging. Every order is covered by our <a href=\"\/cs\/medsbase-re-shipment-assurance-policy\/\" rel=\"noopener\">Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/a> \u2014 pokud nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me bez dal\u0161\u00edch n\u00e1klad\u016f. Podpo\u0159eno v\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdmi recenzemi z\u00e1kazn\u00edk\u016f.<\/p>\n<h2>What is Alphagan P Drop?<\/h2>\n<p>Alphagan P Drop is manufactured by Allergan and contains brimonidine tartrate 0.15% as a sterile ophthalmic solution. Brimonidine is a highly selective alpha-2 adrenergic agonist used to lower IOP in open-angle glaucoma and ocular hypertension. It has a unique dual mechanism \u2014 reducing aqueous humour production AND increasing uveoscleral outflow \u2014 and is one of the few glaucoma drops with a possible neuroprotective effect on retinal ganglion cells suggested by laboratory and small-cohort clinical evidence.<\/p>\n<h2>Jak to funguje<\/h2>\n<p>Brimonidine activates alpha-2 receptors on the ciliary body, decreasing cAMP and reducing aqueous production. It also increases uveoscleral outflow. Average IOP reduction is 18\u201322%. The 0.15% formulation (Alphagan P) uses a Purite preservative system that breaks down in the tear film into water, oxygen, and chloride ions, making it gentler than benzalkonium chloride for long-term use.<\/p>\n<h2>Indikace &amp; D\u00e1vkov\u00e1n\u00ed<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Indikace<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">D\u00e1vka<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Open-angle glaucoma \/ ocular hypertension<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">1 drop in affected eye(s) three times daily (every 8 hours)<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Dopl\u0148kov\u00e1 terapie<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Dvakr\u00e1t denn\u011b<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Post-laser (LPI, SLT) IOP spike prophylaxis<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">1 drop pre-procedure and 1 drop post-procedure<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:12px 16px;margin:14px 0;border-radius:4px;font-size:14px;line-height:1.55;\"><strong style=\"color:#a94442;\">Paediatric apnoea \u2014 avoid in children &lt; 2 years.<\/strong> Brimonidine readily crosses the blood-brain barrier. In children younger than 2, even ophthalmic brimonidine has caused life-threatening CNS depression with apnoea, bradycardia, and hypotension. Avoid in age &lt; 2; use with extreme caution in age 2\u20136 years (Alphagan P 0.1% formulation only, with parental supervision and observation).<\/div>\n<h2>Vedlej\u0161\u00ed \u00fa\u010dinky<\/h2>\n<p><strong>Local (10\u201320%):<\/strong> conjunctival hyperaemia, allergic conjunctivitis (typically appears at 6\u201318 months \u2014 characteristic late onset), follicular conjunctivitis, eye pruritus, foreign body sensation, blurred vision.<\/p>\n<p><strong>Syst\u00e9mov\u00e9:<\/strong> dry mouth, fatigue, drowsiness, headache, hypotension. Children (especially under 6) can develop somnolence and bradycardia.<\/p>\n<h2>Varov\u00e1n\u00ed a kontraindikace<\/h2>\n<ul>\n<li><strong>Children &lt; 2 years<\/strong> \u2014 absolute contraindication (apnoea risk)<\/li>\n<li>Children 2\u20136 years \u2014 use only with caution and supervision<\/li>\n<li>Concurrent MAO inhibitors \u2014 relative contraindication, additive sedation<\/li>\n<li>T\u011b\u017ek\u00e9 kardiovaskul\u00e1rn\u00ed onemocn\u011bn\u00ed, ortostatick\u00e1 hypotenze<\/li>\n<li>Concurrent CNS depressants (alcohol, sedatives, opioids) \u2014 additive sedation<\/li>\n<li>T\u011bhotenstv\u00ed \/ kojen\u00ed \u2014 konzultujte s odborn\u00edkem<\/li>\n<\/ul>\n<h2>Skladov\u00e1n\u00ed<\/h2>\n<p>Skladujte p\u0159i 15\u201325\u00b0C chr\u00e1n\u011bno p\u0159ed sv\u011btlem. Zlikvidujte 28 dn\u00ed po prvn\u00edm otev\u0159en\u00ed.<\/p>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3>Why does Alphagan P Drop cause an allergic reaction late?<\/h3>\n<p>Brimonidine is one of the few glaucoma drops with classic late-onset allergic conjunctivitis \u2014 typically appearing 6\u201318 months into therapy. If your eyes start to feel itchy and red months after a smooth start, this is the likely cause. Stop the drop and discuss alternatives.<\/p>\n<h3>Is Alphagan P Drop neuroprotective?<\/h3>\n<p>Some preclinical and small clinical studies suggest brimonidine may protect retinal ganglion cells beyond the IOP-lowering effect. The Low-Pressure Glaucoma Treatment Study (LoGTS) showed less visual-field progression on brimonidine vs timolol despite equivalent IOP control. The evidence is suggestive rather than definitive.<\/p>\n<h3>Why three times a day?<\/h3>\n<p>Brimonidine has an 8-hour duration of action. Three-times-daily dosing maintains 24-hour IOP control as monotherapy. As an add-on it can usually be twice daily.<\/p>\n<h3>Can I use Alphagan P Drop with my child?<\/h3>\n<p>If your child is under 2 years old, do not use Alphagan P Drop \u2014 it can cause life-threatening apnoea. For children 2\u20136 years, use only under specialist supervision. Children over 6 are generally treated like adults but with closer monitoring for somnolence.<\/p>\n<h3>What is Purite preservative?<\/h3>\n<p>An oxidising preservative that breaks down on contact with the tear film into water, oxygen, and chloride ions. Gentler than benzalkonium chloride for long-term daily use.<\/p>\n<h3>Why does Alphagan P Drop make me feel tired?<\/h3>\n<p>Brimonidine crosses the blood-brain barrier and activates central alpha-2 receptors (similar to clonidine), causing sedation, dry mouth, and mild hypotension. Use punctal occlusion to reduce systemic absorption.<\/p>\n<h3>Can I combine Alphagan P Drop with other glaucoma drops?<\/h3>\n<p>Yes \u2014 additive with prostaglandins, beta-blockers, and CAIs. Wait 5 minutes between bottles. Fixed combinations such as brimonidine+timolol exist.<\/p>\n<h3>What if I take MAO inhibitors?<\/h3>\n<p>Avoid the combination \u2014 additive sedation and hypotension are possible. Discuss with your prescriber.<\/p>\n<h3>Can I drive after using Alphagan P Drop?<\/h3>\n<p>Brimonidine can cause drowsiness, especially when starting or in heat. Wait until you know how it affects you before driving long distances.<\/p>\n<h3>Co kdy\u017e vynech\u00e1m d\u00e1vku?<\/h3>\n<p>Take it as soon as you remember unless the next scheduled dose is close. Do not double up.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3>Dal\u0161\u00ed o\u010dn\u00ed l\u00e9ky<\/h3>\n<p>Z\u00e1kazn\u00edci, kte\u0159\u00ed si prohl\u00ed\u017eej\u00ed tento produkt, tak\u00e9 zva\u017euj\u00ed tyto alternativy v na\u0161\u00ed <a href=\"\/cs\/eye-care\/\">P\u00e9\u010de o o\u010di<\/a> nab\u00eddce:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/xalatan-eye-drop\/\">Xalatan o\u010dn\u00ed kapky (latanoprost)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/azopt-eye-drops\/\">Azopt o\u010dn\u00ed kapky (brinzolamid)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/alphagan-p-drop\/\">Alphagan P kapky (brimonidin)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/iotim-eye-drops\/\">Iotim o\u010dn\u00ed kapky (timolol)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/careprost-eye-drops\/\">Careprost (bimatoprost)<\/a><\/li>\n<\/ul>\n<h3>L\u00e9ka\u0159sk\u00e9 upozorn\u011bn\u00ed<\/h3>\n<p style=\"font-size:13px;color:#555;\">Informace na t\u00e9to str\u00e1nce slou\u017e\u00ed pouze pro vzd\u011bl\u00e1vac\u00ed \u00fa\u010dely a nenahrazuj\u00ed l\u00e9ka\u0159skou pomoc kvalifikovan\u00e9ho oftalmologa nebo optometristy. O\u010dn\u00ed onemocn\u011bn\u00ed mohou rychle ohrozit zrak \u2014 n\u00e1hl\u00e1 ztr\u00e1ta zraku, siln\u00e1 bolest nebo trauma p\u0159edstavuj\u00ed oftalmologickou pohotovost. P\u0159ed zah\u00e1jen\u00edm, ukon\u010den\u00edm nebo zm\u011bnou jak\u00e9koli l\u00e9\u010dby se v\u017edy pora\u010fte s odborn\u00edkem na p\u00e9\u010di o zrak.<\/p>","protected":false},"excerpt":{"rendered":"<p>Alphagan P (brimonidine 0.15%) \u2014 selective alpha-2 agonist eye drop. Three-times-daily IOP control for open-angle glaucoma. Avoid in children under 2 (apnoea risk).<\/p>","protected":false},"featured_media":55868,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3343,3342],"product_tag":[4000,4001],"class_list":{"0":"post-55867","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-eye-care","8":"product_cat-general-health","9":"product_tag-alphagan-p-drop","10":"product_tag-brimonidine","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/55867","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=55867"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/55868"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=55867"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=55867"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=55867"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=55867"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}