{"id":56297,"date":"2024-02-07T06:00:14","date_gmt":"2024-02-07T06:00:14","guid":{"rendered":"https:\/\/medsname.com\/flexabenz-er\/"},"modified":"2026-05-05T05:21:56","modified_gmt":"2026-05-05T05:21:56","slug":"flexabenz-er","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/flexabenz-er\/","title":{"rendered":"Flexabenz ER"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Flexabenz ER?<\/h3>\n<p style=\"margin:0;\"><strong>Flexabenz ER<\/strong> je <strong>cyclobenzaprine 15&nbsp;mg extended-release capsule<\/strong> used as a short-course adjunct for acute musculoskeletal muscle spasm. It offers <strong>denn\u00ed d\u00e1vkov\u00e1n\u00ed<\/strong> with smoother plasma levels and typically less peak-related drowsiness than immediate-release cyclobenzaprine. Usual adult dose is <strong>one 15&nbsp;mg capsule once daily<\/strong> for 2 to 3 weeks maximum; 30&nbsp;mg once daily may be used in patients who need more effect and tolerate the 15&nbsp;mg dose well.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Co z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n<p><strong>Flexabenz ER 15&nbsp;mg<\/strong> is the extended-release capsule form of <strong>cyclobenzaprine<\/strong>, designed for once-daily oral administration. The ER formulation releases cyclobenzaprine gradually over 24 hours, giving a smoother and more prolonged plasma level than the 5&nbsp;mg immediate-release tablet dosed three times daily. This has two clinical benefits: simpler adherence (one dose a day) and fewer dose-related peak side effects (lower peak drowsiness, lower peak anticholinergic effect).<\/p>\n<p>Like all cyclobenzaprine formulations, Flexabenz ER is intended as a <em>short-course<\/em> treatment (2&ndash;3 weeks) for acute painful muscle spasm associated with musculoskeletal injury. It is not a chronic pain medication and is not useful for spasticity from upper motor neuron disease.<\/p>\n<h2 class=\"wp-block-heading\">What Is Flexabenz ER Used For?<\/h2>\n<ul>\n<li>Acute low back pain with muscle spasm<\/li>\n<li>Acute neck pain and cervical strain<\/li>\n<li>Muscle strain of the shoulder, trunk, or limb<\/li>\n<li>Post-traumatic muscle spasm (whiplash, soft-tissue injury)<\/li>\n<li>Myofascial pain syndrome (adjunct)<\/li>\n<li>Fibromyalgia-associated muscle pain and sleep disturbance (off-label, short courses)<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">How Does Flexabenz ER Work?<\/h2>\n<p>The active molecule, cyclobenzaprine, acts at the brainstem (primarily locus coeruleus) to reduce descending excitatory drive to spinal alpha motor neurons. This lowers the tonic muscle spasm that accompanies painful musculoskeletal injury. The ER capsule technology spreads the delivery of the full dose across 12&ndash;24 hours, flattening the plasma peak and giving steady cover.<\/p>\n<h2 class=\"wp-block-heading\">Flexabenz ER Dosing<\/h2>\n<ul>\n<li><strong>Po\u010d\u00e1te\u010dn\u00ed d\u00e1vka:<\/strong> 15&nbsp;mg once daily, with or without food<\/li>\n<li><strong>Increase:<\/strong> to 30&nbsp;mg once daily (two 15&nbsp;mg capsules) if the 15&nbsp;mg dose is tolerated but not fully effective<\/li>\n<li><strong>Duration:<\/strong> up to 2 to 3 weeks<\/li>\n<li><strong>Star\u0161\u00ed pacienti:<\/strong> avoid or use the 5&nbsp;mg immediate-release form instead &mdash; ER cyclobenzaprine at 15&nbsp;mg is generally not recommended in patients &gt; 65 years<\/li>\n<li><strong>Mild hepatic impairment:<\/strong> not recommended<\/li>\n<li><strong>Moderate or severe hepatic impairment:<\/strong> kontraindikov\u00e1no<\/li>\n<\/ul>\n<p>Swallow Flexabenz ER capsules whole. <strong>Do not open, crush, or chew<\/strong> &mdash; this destroys the extended-release matrix and converts a 24-hour dose into an immediate burst, raising peak drowsiness and anticholinergic load.<\/p>\n<p>Many patients take the capsule in the evening to use the drowsiness for sleep.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:16px 0;border-radius:4px;\">\n<p style=\"margin:0;\"><strong>Driving and CNS safety for Flexabenz ER.<\/strong> Centrally-acting muscle relaxants cause drowsiness, dizziness, and slowed reaction time &mdash; especially in the first few days of treatment. Do not drive, operate machinery, or make safety-critical decisions until you know how you react to this medicine. The effect is stronger with alcohol, opioid pain medication, sleeping tablets, or anti-anxiety medication &mdash; avoid these combinations unless your doctor has cleared them. Muscle relaxants are <em>short-course<\/em> medicines &mdash; typically used for 1&ndash;3 weeks at the start of a musculoskeletal injury while physiotherapy and exercise do the longer-term work.<\/p>\n<\/div>\n<h2 class=\"wp-block-heading\">Who Should Not Take Flexabenz ER?<\/h2>\n<ul>\n<li>Known hypersensitivity to cyclobenzaprine<\/li>\n<li>Concurrent MAOI use or within 14 days of stopping one<\/li>\n<li>Acute post-myocardial infarction period<\/li>\n<li>Heart block or significant arrhythmia<\/li>\n<li>Congestive heart failure<\/li>\n<li>Hypertyre\u00f3za<\/li>\n<li>Mild, moderate, or severe hepatic impairment (ER form is contraindicated in all hepatic impairment per label)<\/li>\n<li>Angle-closure glaucoma<\/li>\n<li>Significant urinary retention or prostatic obstruction<\/li>\n<li>Age &gt; 65 years (use immediate-release 5&nbsp;mg instead)<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Vedlej\u0161\u00ed \u00fa\u010dinky<\/h2>\n<ul>\n<li><strong>Velmi \u010dast\u00e9:<\/strong> drowsiness, dry mouth, dizziness, fatigue<\/li>\n<li><strong>\u010cast\u00e9:<\/strong> headache, nausea, constipation, urinary retention, blurred vision, mild palpitations<\/li>\n<li><strong>M\u00e9n\u011b \u010dast\u00e9:<\/strong> confusion (especially if taken in the elderly), raised liver enzymes, skin rash<\/li>\n<li><strong>Vz\u00e1cn\u00e9, ale z\u00e1va\u017en\u00e9:<\/strong> serotonin syndrome with serotonergic drugs (SSRIs, SNRIs, tramadol, MAOIs), cardiac arrhythmias, severe hepatotoxicity<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Interakce s l\u00e9\u010divy<\/h2>\n<ul>\n<li><strong>MAOI<\/strong> \u2014 absolutn\u00ed kontraindikace<\/li>\n<li><strong>SSRIs, SNRIs, tramadol, triptans<\/strong> &mdash; serotonin syndrome risk<\/li>\n<li><strong>Alcohol, opioids, benzodiazepines<\/strong> &mdash; additive CNS depression<\/li>\n<li><strong>Anticholinergn\u00ed l\u00e9ky<\/strong> &mdash; additive anticholinergic load<\/li>\n<li><strong>CYP1A2\/CYP3A4 inhibitors<\/strong> &mdash; raise cyclobenzaprine exposure<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Objedn\u00e1vky a dod\u00e1n\u00ed<\/h2>\n<p>MedsBase offers worldwide shipping on every order. Orders are dispatched in discreet packaging and arrive in branded manufacturer packs. If your preferred pack size is out of stock, contact customer support for an ETA.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:20px 0;border-radius:4px;\">\n<p style=\"margin:0;\"><strong>Zdravotn\u00ed prohl\u00e1\u0161en\u00ed.<\/strong> The information on this page is provided for general education only. It is not a substitute for advice from your own doctor or pharmacist. Talk to a qualified healthcare professional before starting, stopping, or changing therapy, especially if you have a history of ulcer disease, heart disease, kidney disease, asthma, liver disease, or are pregnant.<\/p>\n<\/div>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3 class=\"wp-block-heading\">What is Flexabenz ER used for?<\/h3>\n<p>Flexabenz ER (cyclobenzaprine 15&nbsp;mg extended release) is used for acute muscle spasm from musculoskeletal injury &mdash; low back pain, neck pain, torticollis, and muscle strain. Once-daily dosing with 24-hour cover.<\/p>\n<h3 class=\"wp-block-heading\">How is Flexabenz ER different from Flexabenz 5 mg?<\/h3>\n<p>Same molecule (cyclobenzaprine). Flexabenz 5&nbsp;mg is immediate release, dosed 3 times a day. Flexabenz ER is 15&nbsp;mg extended release, dosed once daily &mdash; smoother plasma profile, simpler schedule, usually less peak drowsiness.<\/p>\n<h3 class=\"wp-block-heading\">Can I crush or open the Flexabenz ER capsule?<\/h3>\n<p>No. The extended-release mechanism must stay intact. Crushing or opening converts the full 15&nbsp;mg into an immediate dose, which raises peak sedation and anticholinergic side effects.<\/p>\n<h3 class=\"wp-block-heading\">How long does Flexabenz ER take to work?<\/h3>\n<p>Muscle-relaxing effect usually begins within 1&ndash;2 hours of the first dose; full effect builds over 3&ndash;5 days of daily use.<\/p>\n<h3 class=\"wp-block-heading\">Should I take Flexabenz ER in the morning or at bedtime?<\/h3>\n<p>Either is acceptable. Many patients take it in the evening to use the drowsiness for sleep; daytime dosing is fine once you know how you react.<\/p>\n<h3 class=\"wp-block-heading\">How long can I take Flexabenz ER?<\/h3>\n<p>Up to 2 to 3 weeks. It is not intended for long-term use.<\/p>\n<h3 class=\"wp-block-heading\">Is Flexabenz ER safe in older adults?<\/h3>\n<p>The 15&nbsp;mg ER dose is generally not recommended in patients over 65 &mdash; anticholinergic and cardiac effects are stronger and clearance is slower. The 5&nbsp;mg immediate-release form, at low doses, is the preferred option in the elderly.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Flexabenz ER with an SSRI?<\/h3>\n<p>Use with caution. Combined use raises the risk of serotonin syndrome. Discuss with your doctor; watch for agitation, confusion, shivering, diarrhoea, rapid heart rate, or fever.<\/p>\n<h3 class=\"wp-block-heading\">Can I drink alcohol while taking Flexabenz ER?<\/h3>\n<p>Avoid alcohol. The combination greatly increases drowsiness and fall risk.<\/p>\n<h3 class=\"wp-block-heading\">Is Flexabenz ER addictive?<\/h3>\n<p>Cyclobenzaprine is not a controlled substance and is not considered to cause meaningful physical dependence. Take as prescribed.<\/p>\n<h3 class=\"wp-block-heading\">Co kdy\u017e vynech\u00e1m d\u00e1vku?<\/h3>\n<p>Take it when you remember unless your next dose is due within 12 hours &mdash; then skip. Never double up.<\/p>\n<p data-mb-link-target=\"synaptol\" data-mb-anchor-variant=\"v2\" style=\"margin-top:1em;font-size:0.95em;color:#444;border-left:3px solid #2c7cb0;padding:0.5em 0.75em;background:#f4f8fb;\"><strong>Viz tak\u00e9:<\/strong> <a href=\"https:\/\/medsbase.com\/cs\/synaptol\/\"><strong>tolperisone alternative (Synaptol)<\/strong><\/a> \u2014 tolperisone alternative when cyclobenzaprine sedation is unacceptable \u2014 centrally acting without H1 antihistamine drowsiness.<\/p>\n<p class=\"medsbase-link-boost-2026-05-05\" data-marker=\"mb-link-boost-synaptol\">Kde <a href=\"https:\/\/medsbase.com\/cs\/flexabenz-er\/\">Flexabenz ER<\/a> (cyclobenzaprine extended-release) delivers strong relief but pronounced anticholinergic side effects, <a href=\"https:\/\/medsbase.com\/cs\/synaptol\/\">Synaptol (tolperisone 50&nbsp;mg)<\/a> offers a non-sedating substitute for spasticity and musculoskeletal spasm without the dry mouth or daytime grogginess.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Souvisej\u00edc\u00ed alternativy<\/h3>\n<p>Dal\u0161\u00ed produkty v <strong>Chronick\u00e1 onemocn\u011bn\u00ed<\/strong> kter\u00e9 z\u00e1kazn\u00edci tak\u00e9 prohl\u00ed\u017eej\u00ed:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/psyquit\/\">Psyquit<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/avonza\/\">Avonza<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/montek-plus\/\">Montek Plus<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/topme-xl\/\">Topme XL<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/prilox-cream\/\">Prilox kr\u00e9m<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Relieves muscle spasms<br \/>\n\u2705 Reduces muscle stiffness<br \/>\n\u2705 Zlep\u0161uje pohyblivost<br \/>\n\u2705 Alleviates musculoskeletal pain<br \/>\n\u2705 Enhances physical therapy effectiveness<\/p>\n<p>Flexabenz ER contains Cyclobenzaprime.<\/p>","protected":false},"featured_media":56298,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3555],"product_tag":[4092,4094],"class_list":{"0":"post-56297","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-pain-relief-medication","9":"product_tag-cyclobenzaprime","10":"product_tag-flexabenz-er","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/56297","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=56297"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/56298"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=56297"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=56297"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=56297"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=56297"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}