{"id":56575,"date":"2024-02-27T16:59:26","date_gmt":"2024-02-27T16:59:26","guid":{"rendered":"https:\/\/medsname.com\/decdan\/"},"modified":"2026-05-01T10:49:13","modified_gmt":"2026-05-01T10:49:13","slug":"decdan","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/decdan\/","title":{"rendered":"Decdan"},"content":{"rendered":"

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\u26a1 Rychl\u00e1 odpov\u011b\u010f \u2014 Co je Decdan?<\/h3>\n

Decdan<\/strong> je dexamethason 0,5 mg peror\u00e1ln\u00ed tableta<\/strong> \u2014 siln\u00fd dlouhodob\u011b p\u016fsob\u00edc\u00ed syntetick\u00fd kortikosteroid pou\u017e\u00edvan\u00fd pro \u0161irok\u00e9 spektrum z\u00e1n\u011btliv\u00fdch, alergick\u00fdch, autoimunitn\u00edch a malign\u00edch stav\u016f. Klinicky je ekvivalentn\u00ed s Dexona 0,5 mg a Decmax 4 mg (stejn\u00e1 molekula v r\u016fzn\u00fdch sil\u00e1ch). Typick\u00e1 denn\u00ed d\u00e1vka je 0,75\u20139 mg v z\u00e1vislosti na indikaci<\/strong>, v\u017edy u\u017e\u00edvan\u00e1 s j\u00eddlem, nejl\u00e9pe r\u00e1no. Nikdy nep\u0159eru\u0161ujte u\u017e\u00edv\u00e1n\u00ed Decdanu n\u00e1hle po dlouhodob\u00e9 l\u00e9\u010db\u011b.<\/p>\n<\/div>\n

\nCo z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n

\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n

Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n

Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n

Decdan 0,5 mg<\/strong> je peror\u00e1ln\u00ed tableta dexamethason<\/strong>, vyr\u00e1b\u011bn\u00fd spole\u010dnost\u00ed Cadila. Dexamethason je jeden z nejsiln\u011bj\u0161\u00edch syntetick\u00fdch glukokortikoid\u016f pou\u017e\u00edvan\u00fdch v rutinn\u00ed klinick\u00e9 praxi \u2014 p\u0159ibli\u017en\u011b 25\u201330kr\u00e1t \u00fa\u010dinn\u011bj\u0161\u00ed na miligram ne\u017e hydrokortizon, bez mineralokortikoidn\u00edho \u00fa\u010dinku a s dlouh\u00fdm biologick\u00fdm polo\u010dasem.<\/p>\n

Decdan 0,5 mg se typicky pou\u017e\u00edv\u00e1 pro:<\/p>\n

    \n
  • \u00dadr\u017ebovou a n\u00edzkod\u00e1vkovou imunosupresivn\u00ed terapii u chronick\u00fdch autoimunitn\u00edch onemocn\u011bn\u00ed<\/li>\n
  • Jemn\u00e9 d\u00e1vkov\u00e1n\u00ed b\u011bhem sni\u017eov\u00e1n\u00ed vy\u0161\u0161\u00edch d\u00e1vek steroid\u016f<\/li>\n
  • Pediatrick\u00e9 d\u00e1vkov\u00e1n\u00ed, kde lze 0,5 mg tablety rozd\u011blit nebo kombinovat pro d\u00e1vky podle hmotnosti<\/li>\n
  • Diagnostick\u00fd dexamethasonov\u00fd supresn\u00ed test (n\u00edzkod\u00e1vkov\u00fd protokol pou\u017e\u00edv\u00e1 1 mg v 23 hodin \u2014 dv\u011b 0,5 mg tablety)<\/li>\n<\/ul>\n

    K \u010demu se Decdan pou\u017e\u00edv\u00e1?<\/h2>\n
      \n
    • Z\u00e1n\u011btliv\u00e9 a alergick\u00e9 stavy \u2014 t\u011b\u017ek\u00e9 vzplanut\u00ed ekz\u00e9mu, alergick\u00e1 r\u00fdma, reakce na l\u00e9ky<\/li>\n
    • Autoimunitn\u00ed onemocn\u011bn\u00ed \u2014 revmatoidn\u00ed artritida, SLE, polymyalgia rheumatica, vaskulitida, z\u00e1n\u011btliv\u00e1 onemocn\u011bn\u00ed st\u0159ev<\/li>\n
    • Astma a exacerbace CHOPN (kr\u00e1tk\u00e9 k\u00fary)<\/li>\n
    • Mozkov\u00fd ed\u00e9m (vy\u0161\u0161\u00ed d\u00e1vky \u2014 4\u201316 mg\/den, obvykle pomoc\u00ed Decmax 4 mg)<\/li>\n
    • Antiemetick\u00e1 ochrana b\u011bhem chemoterapie<\/li>\n
    • T\u011b\u017ek\u00fd COVID-19 vy\u017eaduj\u00edc\u00ed kysl\u00edk (6 mg\/den x 10 dn\u00ed)<\/li>\n
    • Z\u00e1d\u011brov\u00fd syndrom u d\u011bt\u00ed (jednor\u00e1zov\u00e1 d\u00e1vka podle hmotnosti)<\/li>\n
    • Adren\u00e1ln\u00ed hyperplazie (vrozen\u00e1 adren\u00e1ln\u00ed hyperplazie \u2014 specializovan\u00e1 endokrinologick\u00e1 d\u00e1vka)<\/li>\n
    • Bakteri\u00e1ln\u00ed meningitida (pomocn\u00e1 l\u00e9\u010dba pro neurologickou ochranu)<\/li>\n
    • Dexamethasonov\u00fd supresn\u00ed test u Cushingova syndromu<\/li>\n<\/ul>\n

      D\u00e1vkov\u00e1n\u00ed p\u0159\u00edpravku Decdan<\/h2>\n
        \n
      • N\u00edzkod\u00e1vkov\u00e1 udr\u017eovac\u00ed l\u00e9\u010dba:<\/strong> 0,5\u20131 mg denn\u011b (1\u20132 tablety)<\/li>\n
      • M\u00edrn\u00e9 a\u017e st\u0159edn\u00ed z\u00e1n\u011btliv\u00e9 indikace:<\/strong> 0,75\u20133 mg\/den<\/li>\n
      • St\u0159edn\u011b z\u00e1va\u017en\u00e9 indikace:<\/strong> 4\u20136 mg\/den (obvykle pomoc\u00ed p\u0159\u00edpravku Decmax 4 mg)<\/li>\n
      • T\u011b\u017ek\u00e9 stavy, mozkov\u00fd ed\u00e9m:<\/strong> 4\u201316 mg\/den (Decmax 4 mg)<\/li>\n
      • No\u010dn\u00ed supresn\u00ed test:<\/strong> 1 mg v 11 hodin ve\u010der, kortizol odebr\u00e1n n\u00e1sleduj\u00edc\u00ed r\u00e1no<\/li>\n
      • U\u017e\u00edvejte s j\u00eddlem<\/strong>, nejl\u00e9pe r\u00e1no<\/li>\n<\/ul>\n

        Potence a ekvivalence kortikosteroid\u016f<\/h2>\n

        R\u016fzn\u00e9 kortikosteroidy se li\u0161\u00ed p\u0159edev\u0161\u00edm v potenci, d\u00e9lce \u00fa\u010dinku a mineralokortikoidn\u00ed (soli zadr\u017euj\u00edc\u00ed) aktivit\u011b. N\u00ed\u017ee uveden\u00e1 tabulka uv\u00e1d\u00ed klinicky u\u017eite\u010dn\u00e9 ekvivalence \u2014 umo\u017e\u0148uje p\u0159ev\u00e9st d\u00e1vku jednoho steroidu na ekvivalentn\u00ed d\u00e1vku jin\u00e9ho.<\/p>\n\n\n\n\n\n\n\n\n\n
        Kortikosteroid<\/th>\nGlukokortikoidn\u00ed potence<\/th>\nEkvivalentn\u00ed d\u00e1vka<\/th>\nMineralokortikoid<\/th>\nD\u00e9lka<\/th>\n<\/tr>\n<\/thead>\n
        Hydrokortizon<\/td>\n1 (referen\u010dn\u00ed)<\/td>\n20 mg<\/td>\nV\u00fdznamn\u00e1<\/td>\n8\u201312 h<\/td>\n<\/tr>\n
        Prednisolon<\/td>\n4<\/td>\n5 mg<\/td>\nN\u00edzk\u00e1<\/td>\n12\u201336 h<\/td>\n<\/tr>\n
        Methylprednisolon<\/td>\n5<\/td>\n4 mg<\/td>\nMinim\u00e1ln\u00ed<\/td>\n12\u201336 h<\/td>\n<\/tr>\n
        Dexamethasone<\/strong><\/td>\n25\u201330<\/td>\n0,75 mg<\/td>\n\u017d\u00e1dn\u00e9<\/td>\n36\u201354 h<\/td>\n<\/tr>\n
        Betamethason<\/td>\n25\u201330<\/td>\n0,75 mg<\/td>\n\u017d\u00e1dn\u00e9<\/td>\n36\u201354 h<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

        Kdo by nem\u011bl u\u017e\u00edvat Decdan?<\/h2>\n
          \n
        • Syst\u00e9mov\u00e1 pl\u00eds\u0148ov\u00e1 infekce (krom\u011b substitu\u010dn\u00ed terapie p\u0159i adren\u00e1ln\u00ed insuficienci)<\/li>\n
        • \u017div\u00e9 vakc\u00edny b\u011bhem imunosupresivn\u00edch d\u00e1vek (p\u0159ed BCG, MMR, \u017elutou zimnic\u00ed, plan\u00fdmi ne\u0161tovicemi, peror\u00e1ln\u00edm tyfem konzultujte odborn\u00edka)<\/li>\n
        • Aktivn\u00ed nel\u00e9\u010den\u00e1 bakteri\u00e1ln\u00ed infekce (nejprve zahajte antibiotika)<\/li>\n
        • Aktivn\u00ed tuberkul\u00f3za bez kryt\u00ed anti-TB l\u00e9\u010dbou<\/li>\n
        • Zn\u00e1m\u00e1 p\u0159ecitliv\u011blost na \u00fa\u010dinnou l\u00e1tku nebo jakoukoli pomocnou l\u00e1tku<\/li>\n
        • Pou\u017e\u00edvejte s opatrnost\u00ed u: diabetes mellitus, m\u011bstnav\u00e9ho srde\u010dn\u00edho selh\u00e1n\u00ed, hypertenze, osteopor\u00f3zy, peptick\u00e9ho v\u0159edu, psychiatrick\u00fdch poruch, glaukomu, herpes simplex ophthalmicus<\/li>\n
        • T\u011bhotenstv\u00ed: u\u017e\u00edvejte pouze v p\u0159\u00edpad\u011b jasn\u00e9 pot\u0159eby \u2013 prednisolon a hydrokortison pronikaj\u00ed placentou m\u00e9n\u011b ne\u017e dexamethason\/betamethason, kter\u00e9 jsou preferov\u00e1ny, kdy\u017e je zam\u00fd\u0161len \u00fa\u010dinek na plod (nap\u0159. zr\u00e1n\u00ed plic)<\/li>\n<\/ul>\n

          Vedlej\u0161\u00ed \u00fa\u010dinky kortikosteroid\u016f<\/h2>\n

          Vedlej\u0161\u00ed \u00fa\u010dinky kortikosteroid\u016f z\u00e1vis\u00ed na d\u00e1vce a d\u00e9lce pod\u00e1v\u00e1n\u00ed. Kr\u00e1tk\u00e9 k\u00fary (< 2 t\u00fddny) p\u0159i st\u0159edn\u00edch d\u00e1vk\u00e1ch jsou obvykle dob\u0159e sn\u00e1\u0161eny. Del\u0161\u00ed nebo vy\u0161\u0161\u00ed d\u00e1vkov\u00e1n\u00ed vyvol\u00e1v\u00e1 klasick\u00fd \u201cCushingoidn\u00ed\u201d profil.<\/p>\n

          Kr\u00e1tkodob\u00e9 (prvn\u00edch 1\u20132 t\u00fddny):<\/strong><\/p>\n