{"id":56597,"date":"2024-02-27T17:00:37","date_gmt":"2024-02-27T17:00:37","guid":{"rendered":"https:\/\/medsname.com\/reactin-sr\/"},"modified":"2026-05-01T10:49:13","modified_gmt":"2026-05-01T10:49:13","slug":"reactin-sr","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/reactin-sr\/","title":{"rendered":"Reactin SR"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Reactin SR?<\/h3>\n<p style=\"margin:0;\"><strong>Reactin SR<\/strong> je <strong>diclofenac 100&nbsp;mg sustained-release tablet<\/strong>, a once-daily form of one of the most widely used oral NSAIDs. It is indicated for chronic inflammatory conditions &mdash; osteoarthritis, rheumatoid arthritis, ankylosing spondylitis &mdash; and for moderate to severe musculoskeletal pain where steady 24-hour cover is required. Usual adult dose is <strong>one 100&nbsp;mg SR tablet once daily with food<\/strong>. Diclofenac has higher cardiovascular risk than ibuprofen &mdash; use at the lowest effective dose for the shortest reasonable time.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Co z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n<p><strong>Reactin SR 100&nbsp;mg<\/strong> is a sustained-release diclofenac tablet formulated to deliver a steady plasma level over 24 hours from a single daily dose. This is useful for chronic inflammatory pain where round-the-clock anti-inflammatory cover is needed and adherence with multi-dose regimens is difficult.<\/p>\n<p>At 100&nbsp;mg, Reactin SR is the stronger sibling of the 75&nbsp;mg SR diclofenac tablets (Voveran SR). It is typically chosen when:<\/p>\n<ul>\n<li>The patient needs a higher total daily diclofenac dose<\/li>\n<li>Simple once-daily dosing is clinically preferable<\/li>\n<li>Smooth plasma levels are required to avoid peak-related GI symptoms<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">What Is Reactin SR Used For?<\/h2>\n<ul>\n<li>Osteoarthritis &mdash; long-term symptom control<\/li>\n<li>Rheumatoid arthritis<\/li>\n<li>Ankylosing spondylitis<\/li>\n<li>Chronic musculoskeletal pain with inflammatory component<\/li>\n<li>Post-surgical pain (step-down from higher-intensity analgesia)<\/li>\n<li>Low back pain with a marked inflammatory component (short to intermediate courses)<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">How Does Diclofenac Work?<\/h2>\n<p>Diclofenac is a non-selective NSAID. It blocks the cyclooxygenase (COX-1 and COX-2) enzymes that convert arachidonic acid to prostaglandins &mdash; the molecules that drive pain, swelling, and fever at sites of tissue injury. Less prostaglandin means less pain and inflammation. Because COX-1-derived prostaglandins also protect the stomach lining and regulate kidney blood flow, the same mechanism that gives NSAIDs their benefit also accounts for their main side effects.<\/p>\n<h2 class=\"wp-block-heading\">Reactin SR Dosing<\/h2>\n<ul>\n<li><strong>Dosp\u011bl\u00ed:<\/strong> one 100&nbsp;mg SR tablet once daily with food<\/li>\n<li><strong>Maxim\u00e1ln\u00ed d\u00e1vka:<\/strong> 150&nbsp;mg\/day of diclofenac from all sources<\/li>\n<li><strong>Duration:<\/strong> short-course for acute conditions (10&ndash;14 days); longer in chronic inflammatory arthritis with regular review<\/li>\n<li><strong>Star\u0161\u00ed pacienti:<\/strong> use with caution; consider the 75&nbsp;mg SR or 50&nbsp;mg IR form instead<\/li>\n<li><strong>Porucha funkce ledvin:<\/strong> avoid if CrCl &lt; 30&nbsp;mL\/min<\/li>\n<li><strong>Porucha funkce jater:<\/strong> avoid in severe impairment<\/li>\n<\/ul>\n<p>Swallow the SR tablet whole with water, with or after food. <strong>Do not crush, split, or chew<\/strong> &mdash; this destroys the sustained-release matrix and converts a 24-hour dose into an immediate burst, greatly increasing GI and cardiovascular risk.<\/p>\n<p>Take at a consistent time each day (morning with breakfast works for most patients).<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:16px 0;border-radius:4px;\">\n<p style=\"margin:0;\"><strong>GI safety.<\/strong> Every oral NSAID &mdash; including Reactin SR &mdash; carries real risk of gastritis, peptic ulcer, and upper-GI bleeding. Risk is highest in patients over 65, those with prior ulcer disease, and anyone also on low-dose aspirin, corticosteroids, SSRIs, or anticoagulants. Take Reactin SR <em>s j\u00eddlem<\/em>, at the <em>lowest effective dose for the shortest reasonable time<\/em>, and ask your doctor about a proton pump inhibitor (omeprazole, pantoprazole) for courses over 2&ndash;4 weeks.<\/p>\n<\/div>\n<h2 class=\"wp-block-heading\">Who Should Not Take Reactin SR?<\/h2>\n<ul>\n<li>Known hypersensitivity to diclofenac or any NSAID<\/li>\n<li>Active or recurrent peptic ulcer or GI bleed<\/li>\n<li>Aspirin- or NSAID-induced asthma, urticaria, or angioedema<\/li>\n<li>T\u011b\u017ek\u00e9 srde\u010dn\u00ed selh\u00e1n\u00ed (NYHA IV)<\/li>\n<li>Established ischaemic heart disease, peripheral arterial disease, cerebrovascular disease (use an alternative NSAID)<\/li>\n<li>Recent CABG surgery<\/li>\n<li>T\u011b\u017ek\u00e9 jatern\u00ed po\u0161kozen\u00ed<\/li>\n<li>Severe renal impairment (CrCl &lt; 30&nbsp;mL\/min)<\/li>\n<li>Third trimester of pregnancy<\/li>\n<\/ul>\n<h3 class=\"wp-block-heading\">Cardiovascular and renal safety<\/h3>\n<p>All non-aspirin NSAIDs carry some increase in heart attack, stroke, and heart-failure risk &mdash; particularly diclofenac and COX-2 selectives. They can also raise blood pressure and reduce kidney function, especially in elderly patients and in anyone combining an NSAID with an ACE inhibitor\/ARB plus a diuretic. Use the lowest effective dose for the shortest duration, and discuss a long course with your doctor if you have cardiovascular or kidney risk factors.<\/p>\n<h2 class=\"wp-block-heading\">Vedlej\u0161\u00ed \u00fa\u010dinky<\/h2>\n<ul>\n<li><strong>\u010cast\u00e9:<\/strong> dyspepsia, nausea, abdominal pain, headache, dizziness, ankle swelling, rash, diarrhoea or constipation<\/li>\n<li><strong>M\u00e9n\u011b \u010dast\u00e9:<\/strong> peptic ulcer, GI bleeding, hypertension, elevated liver enzymes, tinnitus, reduced kidney function, heart failure aggravation<\/li>\n<li><strong>Vz\u00e1cn\u00e9:<\/strong> myocardial infarction, stroke, severe hepatotoxicity, Stevens-Johnson syndrome, aseptic meningitis, anaphylaxis<\/li>\n<\/ul>\n<p>Stop Reactin SR and seek urgent medical care for: blood in stools or vomit, severe abdominal pain, yellowing of skin or eyes, chest pain, sudden-onset weakness or slurred speech, a widespread or blistering rash, or reduced urine output.<\/p>\n<h2 class=\"wp-block-heading\">Objedn\u00e1vky a dod\u00e1n\u00ed<\/h2>\n<p>MedsBase offers worldwide shipping on every order. Orders are dispatched in discreet packaging and arrive in branded manufacturer packs. If your preferred pack size is out of stock, contact customer support for an ETA.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:20px 0;border-radius:4px;\">\n<p style=\"margin:0;\"><strong>Zdravotn\u00ed prohl\u00e1\u0161en\u00ed.<\/strong> The information on this page is provided for general education only. It is not a substitute for advice from your own doctor or pharmacist. Talk to a qualified healthcare professional before starting, stopping, or changing therapy, especially if you have a history of ulcer disease, heart disease, kidney disease, asthma, liver disease, or are pregnant.<\/p>\n<\/div>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3 class=\"wp-block-heading\">What is Reactin SR used for?<\/h3>\n<p>Reactin SR (diclofenac 100&nbsp;mg sustained-release) is used for chronic inflammatory conditions &mdash; osteoarthritis, rheumatoid arthritis, ankylosing spondylitis &mdash; and for chronic musculoskeletal pain where 24-hour anti-inflammatory cover is required.<\/p>\n<h3 class=\"wp-block-heading\">How is Reactin SR different from Reactin 50 mg?<\/h3>\n<p>Same molecule (diclofenac). Reactin 50&nbsp;mg is immediate release, dosed 2&ndash;3 times a day &mdash; suited to acute short courses. Reactin SR is 100&nbsp;mg sustained release, dosed once a day &mdash; suited to chronic inflammatory conditions where simple once-daily dosing is preferred.<\/p>\n<h3 class=\"wp-block-heading\">How is Reactin SR 100 mg different from Voveran SR 75 mg?<\/h3>\n<p>Both are sustained-release diclofenac. Reactin SR is the stronger 100&nbsp;mg once-daily preparation; Voveran SR is a 75&nbsp;mg preparation, usually dosed twice daily. Choice depends on total daily dose needed and patient preference.<\/p>\n<h3 class=\"wp-block-heading\">Should I take Reactin SR with food?<\/h3>\n<p>Yes &mdash; always. Take with or immediately after food to reduce gastric irritation.<\/p>\n<h3 class=\"wp-block-heading\">Can I split or crush the Reactin SR tablet?<\/h3>\n<p>No. The sustained-release matrix must stay intact. Crushing releases the full 100&nbsp;mg at once, causing a rapid peak and much higher GI and cardiovascular risk.<\/p>\n<h3 class=\"wp-block-heading\">How long does Reactin SR take to work?<\/h3>\n<p>Pain relief usually begins within 1&ndash;2 hours of the first dose. Steady-state anti-inflammatory effect builds over 3&ndash;7 days of daily use.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Reactin SR long-term?<\/h3>\n<p>Yes, for chronic inflammatory arthritis, at the lowest effective dose and with regular review of blood pressure, kidney function, and liver enzymes. A proton pump inhibitor (omeprazole, pantoprazole) is usually co-prescribed for GI protection.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Reactin SR with paracetamol?<\/h3>\n<p>Yes. The combination is safe and commonly used for stronger pain relief via complementary mechanisms.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Reactin SR with another NSAID like ibuprofen?<\/h3>\n<p>No. Never combine two NSAIDs. This adds GI bleed and renal injury risk without additional pain-relief benefit.<\/p>\n<h3 class=\"wp-block-heading\">Can I drink alcohol while on Reactin SR?<\/h3>\n<p>Light drinking is usually tolerated. Regular or heavy drinking sharply raises GI bleed risk &mdash; avoid during treatment.<\/p>\n<h3 class=\"wp-block-heading\">Is Reactin SR safe in pregnancy?<\/h3>\n<p>Avoid after 20 weeks; contraindicated in the third trimester. Use in early pregnancy only on specialist advice.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Souvisej\u00edc\u00ed alternativy<\/h3>\n<p>Dal\u0161\u00ed produkty v <strong>Chronick\u00e1 onemocn\u011bn\u00ed<\/strong> kter\u00e9 z\u00e1kazn\u00edci tak\u00e9 prohl\u00ed\u017eej\u00ed:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/erythego-gel\/\">Erythego Gel<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/okacet\/\">Okacet<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/inmecin-r\/\">Inmecin-R<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/cozartan-h\/\">Cozartan-H<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/nimodip-nimodipine\/\">Nimodip (Nimodipin)<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Sustained pain relief<br \/>\n\u2705 Extended anti-inflammatory action<br \/>\n\u2705 Reduces swelling<br \/>\n\u2705 Manages chronic pain<br \/>\n\u2705 Enhanced joint mobility<\/p>\n<p>Reactin SR contains Diclofenac.<\/p>","protected":false},"featured_media":56598,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3555],"product_tag":[4128,4130],"class_list":{"0":"post-56597","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-pain-relief-medication","9":"product_tag-diclofenac","10":"product_tag-reactin-sr","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/56597","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=56597"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/56598"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=56597"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=56597"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=56597"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=56597"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}