{"id":56848,"date":"2024-02-27T17:10:28","date_gmt":"2024-02-27T17:10:28","guid":{"rendered":"https:\/\/medsname.com\/yaz\/"},"modified":"2026-04-30T10:17:17","modified_gmt":"2026-04-30T10:17:17","slug":"yaz","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/yaz\/","title":{"rendered":"Yaz"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:18px 0;border-radius:4px;\">\n<p style=\"margin:0 0 8px 0;\"><strong>\ud83d\udca1 Rychl\u00e1 odpov\u011b\u010f<\/strong><\/p>\n<p style=\"margin:0;\"><strong>Yaz<\/strong> is a combined oral contraceptive (COC) containing <strong>drospirenone<\/strong> (a 4th-generation progestin with antimineralocorticoid (potassium-sparing) and antiandrogenic activity) with <strong>ethinyl estradiol<\/strong>. Taken once daily, it is ~99% effective with perfect use (~91% with typical use). Pack: drospirenone 3 mg + ethinyl estradiol 0.02 mg (28-tablet 24+4 regimen). Starts working after 7 consecutive days of correct use in a new cycle. Used for contraception and commonly for cycle regulation, heavy periods, acne, and PMS\/PMDD. This is a <strong>low-dose \/ ultra-low-dose<\/strong> formulation \u2014 the estrogen component is at 20 mcg EE or lower, which reduces estrogen-related side effects (nausea, breast tenderness) at a modest cost in cycle control stability.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Co z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n<div style=\"background:#f4f8fb;border-left:4px solid #2c7cb0;padding:14px 20px;margin:16px 0;border-radius:4px;font-size:0.95em;\">\n<strong>\ud83d\udd12 Pro\u010d nakupovat na MedsBase:<\/strong> Ov\u011b\u0159en\u00e9 dod\u00e1vky p\u0159\u00edmo od v\u00fdrobce \u00b7 Diskr\u00e9tn\u00ed celosv\u011btov\u00e1 doprava \u00b7 Bezpe\u010dn\u00e9 platby (kreditn\u00ed karta, kryptom\u011bny) \u00b7 Hodnocen\u00ed 4.9\u2605 od 1 400+ z\u00e1kazn\u00edk\u016f\n<\/div>\n<h2><strong>What Is Yaz?<\/strong><\/h2>\n<p>Yaz is a branded generic combined oral contraceptive containing <strong>drospirenone<\/strong> a <strong>ethinyl estradiol (EE)<\/strong>. It prevents pregnancy through three mechanisms:<\/p>\n<ul>\n<li><strong>Ovulation suppression<\/strong> (primary) \u2014 steady hormone levels prevent the LH surge.<\/li>\n<li><strong>Cervical mucus thickening<\/strong> \u2014 hindering sperm penetration.<\/li>\n<li><strong>Endometrial thinning<\/strong> \u2014 reducing implantation potential.<\/li>\n<\/ul>\n<p>Strengths: <strong>drospirenone 3 mg + ethinyl estradiol 0.02 mg (28-tablet 24+4 regimen)<\/strong>. Manufactured by Bayer.<\/p>\n<h2><strong>Progestin Profile: Drospirenone<\/strong><\/h2>\n<p><strong>VTE (clotting) risk:<\/strong> <strong>Slightly higher VTE risk than LNG<\/strong> (~9\u201312 cases per 10,000 woman-years). The absolute risk remains low but the relative risk vs LNG is ~1.5\u20132\u00d7. Discuss with a clinician if you have clotting risk factors.<\/p>\n<p><strong>Androgenic \/ other activity:<\/strong> <strong>Antiandrogenic<\/strong> \u2014 specifically helpful for acne, PMS\/PMDD, and hirsutism. Also mild diuretic effect may reduce bloating and breast tenderness.<\/p>\n<p><strong>Best-fit users:<\/strong> Acne, PMS\/PMDD, hormonal bloating, women without VTE risk factors.<\/p>\n<h2><strong>Klinick\u00e9 pou\u017eit\u00ed<\/strong><\/h2>\n<ul>\n<li><strong>Contraception<\/strong> \u2014 ~99% effective with perfect use, ~91% typical use.<\/li>\n<li><strong>Menstrual cycle regulation<\/strong> \u2014 for irregular periods.<\/li>\n<li><strong>Heavy menstrual bleeding (menorrhagia)<\/strong> \u2014 reduces blood loss 50%+.<\/li>\n<li><strong>Painful periods (dysmenorrhea)<\/strong> \u2014 reduces prostaglandin-mediated cramps.<\/li>\n<li><strong>Acne vulgaris and PMS\/PMDD<\/strong> \u2014 particularly responsive due to drospirenone&#8217;s antiandrogenic profile.<\/li>\n<li><strong>Endometriosis pain<\/strong> (off-label, continuous-use regimens).<\/li>\n<li><strong>Ovarian cyst prevention<\/strong> and reduced ovarian cancer risk with long-term use.<\/li>\n<\/ul>\n<h2><strong>How to Take Yaz<\/strong><\/h2>\n<ol>\n<li><strong>Start on day 1 of your period<\/strong> for immediate contraceptive protection. Starting at other times requires 7 days of backup contraception.<\/li>\n<li>U\u017eijte <strong>one tablet daily at the same time each day<\/strong> \u2014 set a phone alarm. Consistency is critical.<\/li>\n<li>Follow the pack order. 21-day packs: take one tablet daily for 21 days, then 7 tablet-free days. 28-day packs: take all 28 tablets consecutively (last 7 are placebo\/iron).<\/li>\n<li>Expect a withdrawal bleed during the tablet-free \/ placebo week \u2014 lighter than a natural period.<\/li>\n<li>After the break, start the next pack on the scheduled day regardless of whether bleeding has stopped.<\/li>\n<\/ol>\n<h2><strong>Missed Pill Rules (CRITICAL \u2014 read carefully)<\/strong><\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:12px 0;\">\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Sc\u00e9n\u00e1\u0159<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u00da\u010dinek<\/th>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>1 pill missed (&lt;24 hours late)<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Take the missed pill as soon as you remember. Continue the rest of the pack as normal. No backup needed.<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>2+ pills missed (48+ hours late)<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Take the most recent missed pill immediately. Use condoms or abstain for <strong>7 dnech<\/strong>. If missed pills occurred in the last 7 days of the active pack, <strong>skip the placebo week<\/strong> and start the next pack directly. Consider emergency contraception if unprotected sex in the prior 5 days.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>Vomiting within 2 hours of taking a pill<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Treat as a missed pill. Take another from a spare pack if available, or apply missed-pill rules.<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>Severe diarrhoea for &gt;24 hours<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Treat as missed pills; use backup for 7 days after recovery.<\/td>\n<\/tr>\n<\/table>\n<h2><strong>Vedlej\u0161\u00ed \u00fa\u010dinky<\/strong><\/h2>\n<p><strong>Common, usually transient (improve over 3 cycles):<\/strong> nausea, breast tenderness, headache, mood changes, breakthrough bleeding\/spotting, reduced libido, weight-neutral to slight gain.<\/p>\n<p><strong>M\u00e9n\u011b \u010dast\u00e9:<\/strong> migraine, melasma (skin pigmentation), contact-lens intolerance, chloasma.<\/p>\n<p><strong>Z\u00e1va\u017en\u00e9 (vz\u00e1cn\u00e9, ale d\u016fle\u017eit\u00e9):<\/strong> venous thromboembolism (DVT\/PE), arterial thromboembolism (stroke, MI), hypertension, cholestatic jaundice, hepatic adenoma, breast cancer (small increase during use, returns to baseline within 10 years of stopping).<\/p>\n<p><strong>VTE warning signs \u2014 STOP and seek urgent medical help:<\/strong> severe leg pain or swelling (DVT), sudden shortness of breath or chest pain (PE), sudden severe headache with neurological symptoms (stroke), severe abdominal pain (mesenteric thrombosis).<\/p>\n<h2><strong>Who Should Not Take Yaz<\/strong><\/h2>\n<p>Combined oral contraceptives are <strong>absolutely contraindicated<\/strong> in:<\/p>\n<ul>\n<li><strong>Smoking + age \u226535<\/strong> \u2014 dramatic stroke\/MI risk increase.<\/li>\n<li>History of VTE (DVT or PE), thrombophilia (Factor V Leiden, protein C\/S deficiency, antiphospholipid antibodies).<\/li>\n<li>History of stroke, transient ischaemic attack, or coronary artery disease.<\/li>\n<li><strong>Migraine with aura<\/strong> \u2014 significant stroke risk.<\/li>\n<li>Uncontrolled hypertension (&gt;160\/100 mmHg).<\/li>\n<li>Active or recent (within 10 years) breast cancer.<\/li>\n<li>Active liver disease (hepatitis, cirrhosis, tumour).<\/li>\n<li>Known pregnancy or unexplained vaginal bleeding.<\/li>\n<li>Major surgery with prolonged immobilisation (stop 4 weeks before).<\/li>\n<li>Breastfeeding under 6 weeks postpartum (reduces milk supply; VTE risk high).<\/li>\n<li>Severe diabetes with vascular complications.<\/li>\n<\/ul>\n<h2><strong>Interakce s l\u00e9\u010divy<\/strong><\/h2>\n<ul>\n<li><strong>Enzyme inducers (REDUCE contraceptive effect \u2014 backup needed):<\/strong> rifampicin, rifabutin, phenytoin, phenobarbital, carbamazepine, topiramate, primidone, some HIV antiretrovirals (ritonavir, efavirenz), St John&#8217;s Wort.<\/li>\n<li><strong>Antibiotics (most do NOT reduce efficacy)<\/strong> \u2014 the old advice to use backup during antibiotics applies only to rifampicin\/rifabutin. Other antibiotics (amoxicillin, doxycycline, cephalexin) do not reduce COC efficacy for most women.<\/li>\n<li><strong>Lamotrigine<\/strong> \u2014 COCs reduce lamotrigine levels; dose adjustment may be needed.<\/li>\n<li><strong>Drospirenone + potassium-sparing drugs<\/strong> (ACE inhibitors, ARBs, K+-sparing diuretics, NSAIDs long-term): small hyperkalaemia risk. Check potassium in the first cycle if combining.<\/li>\n<li><strong>Grapefruitov\u00e1 \u0161\u0165\u00e1va<\/strong> \u2014 may raise estrogen levels modestly; not clinically significant.<\/li>\n<\/ul>\n<h2><strong>Non-Contraceptive Benefits<\/strong><\/h2>\n<ul>\n<li>~50% reduction in ovarian cancer risk with 5+ years of use (persists decades after stopping).<\/li>\n<li>~50% reduction in endometrial cancer risk.<\/li>\n<li>Lighter, shorter, more predictable periods.<\/li>\n<li>Reduced menstrual cramps, mittelschmerz, and PMS symptoms.<\/li>\n<li>Improved acne (especially drospirenone- or cyproterone-containing COCs).<\/li>\n<li>Reduction in benign ovarian cysts and fibrocystic breast changes.<\/li>\n<li>Potential protective effect against pelvic inflammatory disease (thickened cervical mucus).<\/li>\n<\/ul>\n<h2><strong>Skladov\u00e1n\u00ed<\/strong><\/h2>\n<p>Store at room temperature (15\u201325 \u00b0C \/ 59\u201377 \u00b0F) in the original blister. Keep out of direct sunlight and humidity. Do not use after the printed expiry date. Keep out of reach of children.<\/p>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3 class=\"wp-block-heading\">How quickly does Yaz work?<\/h3>\n<p>If started on day 1 of your period, it is effective immediately. Starting any other day requires 7 days of backup contraception (condoms or abstinence).<\/p>\n<h3 class=\"wp-block-heading\">What happens if I want to get pregnant?<\/h3>\n<p>Fertility usually returns within 1\u20133 months of stopping. Some women conceive the first cycle after discontinuation. Taking folic acid for 3 months before trying is recommended.<\/p>\n<h3 class=\"wp-block-heading\">Will Yaz make me gain weight?<\/h3>\n<p>Modern low-dose COCs are generally weight-neutral in placebo-controlled trials. Some women report 1\u20132 kg changes but this is often fluid retention that resolves after 3 months. Drospirenone-containing COCs (mild diuretic effect) may be weight-favourable.<\/p>\n<h3 class=\"wp-block-heading\">Can I use Yaz to skip my period?<\/h3>\n<p>Yes \u2014 &#8220;tricycling&#8221; or continuous use is safe for most women. Skip the tablet-free week and start the next pack directly to delay or skip the withdrawal bleed. Some breakthrough spotting may occur; discuss with a clinician for long-term continuous use.<\/p>\n<h3 class=\"wp-block-heading\">Is Yaz safe if I am overweight?<\/h3>\n<p>Moderate obesity (BMI 30\u201335) does not absolutely contraindicate COCs but increases VTE risk. Progestin-only pills or non-hormonal methods may be preferable if BMI is &gt;35. Discuss with a clinician.<\/p>\n<h3 class=\"wp-block-heading\">What about breastfeeding?<\/h3>\n<p>Combined pills are not recommended for breastfeeding mothers under 6 weeks postpartum (VTE risk + milk supply reduction). Progestin-only pills (mini-pills) are preferred during breastfeeding.<\/p>\n<h3 class=\"wp-block-heading\">Does Yaz protect against STIs?<\/h3>\n<p>No. Hormonal contraceptives provide zero protection against STIs. Use condoms as barrier protection against chlamydia, gonorrhoea, HIV, herpes, syphilis, and HPV.<\/p>\n<h3 class=\"wp-block-heading\">What if I forget a pill?<\/h3>\n<p>See the Missed Pill Rules table above. Briefly: 1 pill missed (&lt;24 h late) = take and continue; 2+ pills missed (48+ h late) = take the most recent + 7 days backup.<\/p>\n<h3 class=\"wp-block-heading\">When should I call a doctor urgently?<\/h3>\n<p>Severe leg pain or swelling (possible DVT), chest pain or shortness of breath (possible PE), severe headache with visual\/neurological changes (possible stroke), severe abdominal pain, yellowing of skin or eyes (liver problem).<\/p>\n<h3 class=\"wp-block-heading\">Can I switch from Yaz to a different pill?<\/h3>\n<p>Yes \u2014 start the new pill the day after finishing the current pack (no tablet-free gap) if switching another COC. If switching to a POP, overlap by 7 days. Always consult a clinician if changing due to side effects or health changes.<\/p>\n<h3 class=\"wp-block-heading\">Related Contraceptive Products<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/yasmin\/\">Yasmin (Drospirenone + EE)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/ovral-l\/\">Ovral-L (Levonorgestrel + EE)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/ovral-g\/\">Ovral-G (Norgestrel + EE)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/loette\/\">Loette (LNG + EE ultra-low)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/duoluton-l\/\">Duoluton-L (LNG + EE)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/triquilar\/\">Triquilar (Triphasic LNG + EE)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/femilon\/\">Femilon (Desogestrel + EE low-dose)<\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 20px;margin:16px 0;border-radius:4px;font-size:0.9em;\">\n<p style=\"margin:0;\"><strong>\u2695\ufe0f L\u00e9ka\u0159sk\u00e9 upozorn\u011bn\u00ed:<\/strong> Hormonal contraceptives have contraindications and interactions. Consult a clinician before starting. If you smoke and are over 35, have migraine with aura, a history of VTE, active liver disease, or known cardiovascular disease, combined oral contraceptives may not be safe for you. Emergency contraception is not a substitute for regular birth control.<\/p>\n<\/div>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Souvisej\u00edc\u00ed alternativy<\/h3>\n<p>Dal\u0161\u00ed produkty v <strong>L\u00e9\u010dba akn\u00e9<\/strong> kter\u00e9 z\u00e1kazn\u00edci tak\u00e9 prohl\u00ed\u017eej\u00ed:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/isotroin\/\">Isotroin<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/epilite\/\">Epilite<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/melacare-forte-cream\/\">Melacare Forte kr\u00e9m<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/tretinex-cream\/\">Tretinex Cream<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/isofair\/\">Isofair<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p><span style=\"font-weight: 400;\">\u2705 Prevents Pregnancy<br \/>\n<\/span><span style=\"font-weight: 400;\">\u2705 Regulates Menstrual Cycle<br \/>\n<\/span><span style=\"font-weight: 400;\">\u2705 Sni\u017euje v\u00fdskyt akn\u00e9<br \/>\n<\/span><span style=\"font-weight: 400;\">\u2705 Decreases Menstrual Cramps<br \/>\n<\/span><span style=\"font-weight: 400;\">\u2705 Prescribed Birth Control<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Yaz contains Drospirenone and Ethinylestradiol.<\/span><\/p>","protected":false},"featured_media":56849,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3215,3530,3141,3223,3502],"product_tag":[4183,4186,4187],"class_list":{"0":"post-56848","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-acne-treatment","7":"product_cat-alternative-contraceptives","8":"product_cat-category-overview","9":"product_cat-chronic-conditions","10":"product_cat-womens-health","11":"product_tag-drospirenone","12":"product_tag-ethinylestradiol","13":"product_tag-yaz","15":"first","16":"instock","17":"shipping-taxable","18":"purchasable","19":"product-type-variable","20":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/56848","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=56848"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/56849"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=56848"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=56848"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=56848"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=56848"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}