{"id":56873,"date":"2024-02-27T17:11:43","date_gmt":"2024-02-27T17:11:43","guid":{"rendered":"https:\/\/medsname.com\/dutanol\/"},"modified":"2026-05-01T05:17:56","modified_gmt":"2026-05-01T05:17:56","slug":"dutanol","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/dutanol\/","title":{"rendered":"Dutanol"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:18px 0;border-radius:4px;\">\n<p style=\"margin:0 0 8px 0;\"><strong>\ud83d\udca1 Rychl\u00e1 odpov\u011b\u010f<\/strong><\/p>\n<p style=\"margin:0;\"><strong>Dutanol<\/strong> je <strong>dutasteride 0.5 mg<\/strong>, a dual type-1 and type-2 5-alpha-reductase inhibitor. FDA-approved for BPH; widely used off-label for male-pattern hair loss where it suppresses scalp DHT by ~90% (vs ~70% for finasteride) \u2014 giving stronger hair regrowth results in trials but with somewhat higher sexual side-effect risk and a very long half-life (~5 weeks).<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Co z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n<div style=\"background:#f4f8fb;border-left:4px solid #2c7cb0;padding:14px 20px;margin:16px 0;border-radius:4px;font-size:0.95em;\">\n<strong>\ud83d\udd12 Pro\u010d nakupovat na MedsBase:<\/strong> Ov\u011b\u0159en\u00e9 dod\u00e1vky p\u0159\u00edmo od v\u00fdrobce \u00b7 Diskr\u00e9tn\u00ed celosv\u011btov\u00e1 doprava \u00b7 Bezpe\u010dn\u00e9 platby (kreditn\u00ed karta, kryptom\u011bny) \u00b7 Hodnocen\u00ed 4.9\u2605 od 1 400+ z\u00e1kazn\u00edk\u016f\n<\/div>\n<h2><strong>What Is Dutanol?<\/strong><\/h2>\n<p>Dutanol is a branded generic of <strong>dutasteride 0.5 mg<\/strong>, , <strong>dual inhibitor<\/strong> of both type-1 and type-2 5-alpha-reductase enzymes. This is more comprehensive than finasteride (which only blocks type-2), producing ~90% reduction in circulating DHT vs finasteride&#8217;s ~70%.<\/p>\n<p>Dutasteride is FDA-approved for benign prostatic hyperplasia (BPH). For <strong>male-pattern hair loss it is used off-label in most countries<\/strong> (it is formally approved for AGA in South Korea and Japan). In head-to-head trials vs finasteride for AGA, dutasteride produces somewhat greater hair-count improvements \u2014 at the cost of slightly higher side-effect incidence. Manufactured by Panacea Biotec.<\/p>\n<h2><strong>Klinick\u00e9 pou\u017eit\u00ed<\/strong><\/h2>\n<ul>\n<li><strong>Male-pattern baldness (off-label):<\/strong> 0.5 mg daily. Considered when finasteride response is inadequate after 12 months.<\/li>\n<li><strong>Benign\u00ed hyperplazie prostaty (BPH):<\/strong> 0.5 mg daily. Reduces prostate volume, improves urinary symptoms, lowers acute-urinary-retention risk, and reduces need for BPH-related surgery.<\/li>\n<li><strong>Female-pattern hair loss:<\/strong> emerging off-label use in selected cases; contraindicated in pregnancy.<\/li>\n<\/ul>\n<h2><strong>Jak u\u017e\u00edvat<\/strong><\/h2>\n<ol>\n<li>Swallow the capsule whole with water. Do not chew, crush, or open \u2014 skin contact with the liquid contents should be avoided (risk to pregnant women especially).<\/li>\n<li>Take at roughly the same time each day. With or without food.<\/li>\n<li>Expect a slower onset than finasteride \u2014 <strong>6+ months before meaningful response<\/strong>. Peak effect at 12\u201318 months.<\/li>\n<li>Dutasteride has a <strong>very long half-life (~5 weeks)<\/strong>. Missing a single dose is not a clinical problem, but do not skip days regularly.<\/li>\n<li>Continuous daily use is required \u2014 discontinuation reverses hair gains over 6\u201312 months. Stopping dutasteride takes longer for the drug to clear (months) than stopping finasteride (days).<\/li>\n<\/ol>\n<h2><strong>Finasteride vs Dutasteride \u2014 Decision Framework<\/strong><\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:12px 0;\">\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Dimension<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Finasteride 1 mg<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Dutasteride 0.5 mg<\/th>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">DHT suppression<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">~70%<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">~90%<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Hair regrowth (trials)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Strong, well-validated<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">~25% greater hair count vs finasteride<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Sexual side effects<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">1\u20132%<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">~2\u20134%<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Polo\u010das<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">~6 hours<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">~5 weeks<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">FDA approval for AGA<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Ano<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">No (off-label)<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Cena<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Lower (generic widely available)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">St\u0159edn\u00ed<\/td>\n<\/tr>\n<\/table>\n<p>See our full guide: <a href=\"https:\/\/medsbase.com\/cs\/finasteride-vs-dutasteride\/\"><strong>Finasteride vs Dutasteride<\/strong><\/a>.<\/p>\n<h2><strong>Vedlej\u0161\u00ed \u00fa\u010dinky<\/strong><\/h2>\n<p><strong>Common (2\u20134%):<\/strong> decreased libido, erectile dysfunction, reduced ejaculate volume, gynecomastia.<\/p>\n<p><strong>M\u00e9n\u011b \u010dast\u00e9:<\/strong> breast tenderness, depression, anxiety.<\/p>\n<p><strong>Persistent sexual effects<\/strong> after discontinuation have been reported and are discussed in the same framework as post-finasteride syndrome. Slightly more concerning with dutasteride given the very long half-life (~5 weeks), meaning effects persist longer after stopping.<\/p>\n<h2><strong>Who Should Not Take Dutanol<\/strong><\/h2>\n<ul>\n<li><strong>Women of reproductive age<\/strong> \u2014 teratogenic. Do not handle leaking capsules. Pregnancy is an absolute contraindication.<\/li>\n<li>Known hypersensitivity to dutasteride or finasteride<\/li>\n<li>Severe hepatic impairment \u2014 use with caution<\/li>\n<li>Note: dutasteride <strong>halves PSA<\/strong> readings (same as finasteride). Always disclose before PSA testing.<\/li>\n<\/ul>\n<h2><strong>Interakce s l\u00e9\u010divy<\/strong><\/h2>\n<ul>\n<li><strong>Siln\u00e9 inhibitory CYP3A4<\/strong> (ketoconazole, ritonavir): raise dutasteride levels \u2014 caution.<\/li>\n<li><strong>PSA testing<\/strong>: halves measured PSA \u2014 convention is to double for interpretation.<\/li>\n<li>No significant interactions with minoxidil \u2014 combining dutasteride + topical minoxidil is a common and effective regimen for poor finasteride responders.<\/li>\n<\/ul>\n<h2><strong>Skladov\u00e1n\u00ed<\/strong><\/h2>\n<p>Store at room temperature (15\u201330 \u00b0C \/ 59\u201386 \u00b0F), away from moisture, heat, and direct light. Do not refrigerate. Keep capsules in original blister. Keep away from women of reproductive age \u2014 teratogenic via skin contact with leaking capsules.<\/p>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3 class=\"wp-block-heading\">When should I choose dutasteride over finasteride?<\/h3>\n<p>Most men should start with finasteride (1 mg) \u2014 FDA-approved, lower cost, extensively validated. Consider switching or adding dutasteride if finasteride response is inadequate after 12 months of continuous use, or if you specifically want maximum DHT suppression and accept the slightly elevated side-effect risk.<\/p>\n<h3 class=\"wp-block-heading\">How long until Dutanol works?<\/h3>\n<p>Slower than finasteride. Expect ~6 months for initial effect, 12\u201318 months for peak response. Dutasteride&#8217;s long half-life means slower titration into the body \u2014 and slower clearance if you stop.<\/p>\n<h3 class=\"wp-block-heading\">Can I combine Dutanol with minoxidil?<\/h3>\n<p>Yes \u2014 combining topical minoxidil with dutasteride is a common regimen and studies support additive benefit. This is the typical approach for men with aggressive or poorly-finasteride-responsive AGA.<\/p>\n<h3 class=\"wp-block-heading\">Is dutasteride really worth it over finasteride?<\/h3>\n<p>Head-to-head trials show ~25% greater hair count improvement at 6\u201312 months with dutasteride vs finasteride. For men plateau-ing on finasteride, this may be a meaningful gain. The trade-off is slightly higher sexual side-effect risk and slower clearance.<\/p>\n<h3 class=\"wp-block-heading\">What about PSA?<\/h3>\n<p>Dutasteride halves PSA \u2014 same effect as finasteride. Always disclose your use before any PSA test so the value can be interpreted correctly (typical convention: double the measured value).<\/p>\n<h3 class=\"wp-block-heading\">Does Dutanol cause permanent side effects?<\/h3>\n<p>Very low incidence, but persistent sexual side effects after stopping have been reported. The 5-week half-life means effects clear slowly after discontinuation. If sexual side effects occur, discuss stopping sooner rather than waiting and hoping.<\/p>\n<h3 class=\"wp-block-heading\">Can I stop Dutanol abruptly?<\/h3>\n<p>Yes \u2014 no withdrawal syndrome. But because the drug has a ~5-week half-life, pharmacological effects persist for 2\u20133 months after your last dose. Hair gains reverse over 6\u201312 months.<\/p>\n<h3 class=\"wp-block-heading\">Should women take Dutanol?<\/h3>\n<p>Dutasteride is used off-label in some cases of female-pattern hair loss \u2014 but is absolutely contraindicated in pregnancy or women who might become pregnant. Most female-pattern hair loss is treated with 2% minoxidil (topical), spironolactone (oral), or combinations thereof.<\/p>\n<h3 class=\"wp-block-heading\">Souvisej\u00edc\u00ed produkty a pr\u016fvodci<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/finasteride-vs-dutasteride\/\">Finasteride vs Dutasteride Guide<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/minoxidil-5-vs-10-percent\/\">Minoxidil 5% vs 10% Guide<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/everything-you-need-to-know-about-hair-loss\/\">Everything About Hair Loss<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/how-to-stop-hair-loss-a-guide-to-saving-your-hair\/\">How to Stop Hair Loss<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/can-you-prevent-hair-loss-before-its-too-late\/\">Can You Prevent Hair Loss?<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/tugain-foam\/\">Tugain Foam (Minoxidil 5%)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/tugain-solution\/\">Tugain Solution (Minoxidil 10%)<\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 20px;margin:16px 0;border-radius:4px;font-size:0.9em;\">\n<p style=\"margin:0;\"><strong>\u2695\ufe0f L\u00e9ka\u0159sk\u00e9 upozorn\u011bn\u00ed:<\/strong> Information on this page is for educational purposes and does not replace medical advice. Always consult a qualified clinician before starting, stopping, or changing any medication. Prescription products should be used only under medical supervision.<\/p>\n<\/div>\n<p class=\"medsbase-link-boost-2026-04-30\" data-marker=\"mb-link-boost-minoxytop\">Dutasteride monotherapy can be enhanced with topical minoxidil for additive hair-density gains \u2014 pair with <a href='\/cs\/minoxytop\/'>Minoxytop (minoxidil 5% topical solution)<\/a> for the standard 5\u03b1-reductase-inhibitor + minoxidil combination used in clinical practice.<\/p>\n<p data-mb-link-target=\"minoxytop\" style=\"margin-top:1em;font-size:0.95em;color:#444;border-left:3px solid #2c7cb0;padding:0.5em 0.75em;background:#f4f8fb;\"><strong>Viz tak\u00e9:<\/strong> <a href=\"https:\/\/medsbase.com\/cs\/minoxytop\/\"><strong>Minoxytop 5 mg<\/strong><\/a> \u2014 oral minoxidil for non-responders to topical \u2014 Curatio Healthcare 1.25 \/ 2.5 \/ 5 mg tablets.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Souvisej\u00edc\u00ed alternativy<\/h3>\n<p>Dal\u0161\u00ed produkty v <strong>Mu\u017esk\u00e9 zdrav\u00ed<\/strong> kter\u00e9 z\u00e1kazn\u00edci tak\u00e9 prohl\u00ed\u017eej\u00ed:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/sildisoft\/\">Sildisoft<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/megalis\/\">Megalis<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/malegra-dxt\/\">Malegra DXT<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/tugain-solution\/\">Tugain Solution<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/clomiford\/\">Clomiford<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p><span style=\"font-weight: 400;\">\u2705 Treats Hair Loss<br \/>\n<\/span><span style=\"font-weight: 400;\">\u2705 Promotes Hair Growth<br \/>\n\u2705 Prevents Baldness<br \/>\n<\/span><span style=\"font-weight: 400;\">\u2705 Improves Scalp Health<br \/>\n<\/span><span style=\"font-weight: 400;\">\u2705 Prescribed by Dermatologists<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dutanol contains Dutastride.<\/span><\/p>","protected":false},"featured_media":56874,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3202,3141,3471,3142],"product_tag":[4189,4190],"class_list":{"0":"post-56873","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-benign-prostatic-hyperplasia-bph-treatment","7":"product_cat-category-overview","8":"product_cat-hair-loss-treatment-for-men","9":"product_cat-mens-health","10":"product_tag-dutanol","11":"product_tag-dutastride","13":"first","14":"instock","15":"shipping-taxable","16":"purchasable","17":"product-type-variable","18":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/56873","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=56873"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/56874"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=56873"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=56873"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=56873"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=56873"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}