{"id":57092,"date":"2024-02-27T17:23:36","date_gmt":"2024-02-27T17:23:36","guid":{"rendered":"https:\/\/medsname.com\/floricot\/"},"modified":"2026-05-01T10:49:13","modified_gmt":"2026-05-01T10:49:13","slug":"floricot","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/floricot\/","title":{"rendered":"Floricot"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Floricot?<\/h3>\n<p style=\"margin:0;\"><strong>Floricot<\/strong> je <strong>fludrocortisone acetate 100&nbsp;mcg (0.1&nbsp;mg) tablet<\/strong>, the standard oral <strong>mineralocorticoid replacement<\/strong> used in <strong>primary adrenal insufficiency (Addison&#8217;s disease)<\/strong>, <strong>congenital adrenal hyperplasia<\/strong> (salt-losing forms), and <strong>severe neurogenic orthostatic hypotension<\/strong>. Obvykl\u00e1 d\u00e1vka pro dosp\u011bl\u00e9 je <strong>50&ndash;200&nbsp;mcg once daily<\/strong> for adrenal replacement, and up to <strong>400&nbsp;mcg\/day<\/strong> for neurogenic orthostatic hypotension. Fludrocortisone promotes salt and water retention, which raises blood pressure &mdash; it is <em>ne<\/em> an antihypertensive.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Co z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n<p><strong>Floricot 100&nbsp;mcg<\/strong> je peror\u00e1ln\u00ed tableta obsahuj\u00edc\u00ed <strong>fludrocortisone acetate<\/strong>, a synthetic steroid with potent mineralocorticoid activity and moderate glucocorticoid activity. It is on the WHO Essential Medicines List as the standard oral mineralocorticoid replacement.<\/p>\n<p>Fludrocortisone is essentially a pharmacological substitute for <strong>aldosterone<\/strong> &mdash; the natural mineralocorticoid hormone produced by the adrenal cortex, which regulates sodium and potassium balance. When the adrenal glands cannot produce enough aldosterone (Addison&#8217;s disease, congenital adrenal hyperplasia), fludrocortisone is used to restore normal salt and water balance.<\/p>\n<p>Because salt and water retention raises circulating blood volume, fludrocortisone <strong>raises blood pressure<\/strong> &mdash; which is also why it is used in selected patients with severe <em>orthostatic<\/em> hypotension who faint on standing.<\/p>\n<h2 class=\"wp-block-heading\">What Is Floricot Used For?<\/h2>\n<ul>\n<li><strong>Primary adrenal insufficiency (Addison&#8217;s disease)<\/strong> &mdash; lifelong mineralocorticoid replacement, alongside a glucocorticoid (hydrocortisone or prednisolone)<\/li>\n<li><strong>Salt-losing congenital adrenal hyperplasia (CAH)<\/strong> &mdash; paediatric and adult lifelong replacement, under endocrinology specialist<\/li>\n<li><strong>Neurogenic orthostatic hypotension<\/strong> &mdash; autonomic failure (Parkinson&#8217;s disease, multiple system atrophy, pure autonomic failure, diabetic autonomic neuropathy)<\/li>\n<li><strong>Chronic postural (orthostatic) hypotension<\/strong> &mdash; when non-pharmacological measures (increased salt and water, compression stockings, head-of-bed elevation) are not enough<\/li>\n<li><strong>Refractory postural orthostatic tachycardia syndrome (POTS)<\/strong> &mdash; specialist cardiology use<\/li>\n<li><strong>Severe recurrent vasovagal syncope<\/strong> &mdash; occasional off-label use<\/li>\n<li><strong>Hyperkalaemic periodic paralysis<\/strong> &mdash; specialist neurology use<\/li>\n<li><strong>Type IV renal tubular acidosis with hyperkalaemia<\/strong> &mdash; to promote potassium excretion<\/li>\n<\/ul>\n<p><strong>Pozn\u00e1mka k v\u00fdpisu \u201cBP\u201d.<\/strong> Floricot raises blood pressure rather than lowering it &mdash; it is not a hypertension medicine. The BP category listing likely reflects its role in orthostatic hypotension (low BP on standing). For essential hypertension, thiazides, ACE inhibitors, ARBs, calcium channel blockers, and beta-blockers are the appropriate classes.<\/p>\n<h2 class=\"wp-block-heading\">How Does Fludrocortisone Work?<\/h2>\n<p>Fludrocortisone binds mineralocorticoid receptors in the distal tubule of the kidney and promotes:<\/p>\n<ul>\n<li><strong>Sodium and water reabsorption<\/strong> &mdash; expanding circulating blood volume<\/li>\n<li><strong>Potassium and hydrogen-ion excretion<\/strong> &mdash; lowering serum potassium and correcting acidosis<\/li>\n<li><strong>Blood-pressure rise<\/strong> &mdash; via expanded intravascular volume and increased peripheral vascular sensitivity to endogenous catecholamines<\/li>\n<\/ul>\n<p>Fludrocortisone also has weak glucocorticoid activity &mdash; about 1 mg fludrocortisone equals roughly 10 mg hydrocortisone for anti-inflammatory effect &mdash; but it is rarely used for that purpose because purer glucocorticoids are available.<\/p>\n<h2 class=\"wp-block-heading\">Floricot Dosing<\/h2>\n<ul>\n<li><strong>Primary adrenal insufficiency (Addison&#8217;s):<\/strong> 50&ndash;200 mcg once daily in the morning<\/li>\n<li><strong>Salt-losing CAH (children):<\/strong> weight-based, typically 50&ndash;300 mcg\/day, under paediatric endocrinology<\/li>\n<li><strong>Severe neurogenic orthostatic hypotension:<\/strong> start at 100 mcg once daily; titrate up to 400 mcg\/day in divided doses as tolerated, monitoring supine BP, serum potassium, and for pedal oedema<\/li>\n<li><strong>POTS, refractory vasovagal syncope:<\/strong> 100&ndash;200 mcg daily (specialist cardiology)<\/li>\n<\/ul>\n<p>Take with food to reduce gastric irritation. Morning dosing mimics natural cortisol rhythm and is preferred. Swallow whole with water.<\/p>\n<p>Dose adjustments: <strong>never stop abruptly in adrenal insufficiency<\/strong> &mdash; this will trigger an Addisonian crisis. Any dose change should be gradual and monitored.<\/p>\n<h2 class=\"wp-block-heading\">Who Should Not Take Floricot?<\/h2>\n<ul>\n<li>Known hypersensitivity to fludrocortisone or any excipient<\/li>\n<li>Systemic fungal infection<\/li>\n<li>Untreated severe hypertension (because fludrocortisone will worsen it)<\/li>\n<li>Uncontrolled heart failure (salt retention will worsen oedema)<\/li>\n<li>Severe osteoporosis (mineralocorticoid does not protect against steroid-induced bone loss)<\/li>\n<li>Use with caution in: diabetes mellitus (hyperglycaemia), renal impairment, peptic ulcer, psychiatric disease, glaucoma, cirrhosis<\/li>\n<li>Pregnancy &mdash; use only if necessary, under endocrinology supervision; essential in adrenal insufficiency<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Vedlej\u0161\u00ed \u00fa\u010dinky<\/h2>\n<ul>\n<li><strong>Common (dose-dependent):<\/strong> fluid retention, ankle oedema, weight gain, raised blood pressure (supine hypertension), hypokalaemia (low potassium &mdash; leg cramps, muscle weakness), metabolic alkalosis<\/li>\n<li><strong>M\u00e9n\u011b \u010dast\u00e9:<\/strong> headache, insomnia, mild glucose intolerance, easy bruising (glucocorticoid component)<\/li>\n<li><strong>Vz\u00e1cn\u00e9, ale z\u00e1va\u017en\u00e9:<\/strong> heart failure aggravation (in pre-existing cardiac disease), severe hypokalaemia, osteoporosis (long-term), cataracts (very long-term), rarely severe hypersensitivity<\/li>\n<\/ul>\n<p>For neurogenic orthostatic hypotension specifically, patients should be warned about <strong>supine hypertension<\/strong> &mdash; blood pressure when lying flat can rise excessively. Practical measures: elevate the head of the bed 10&ndash;15&nbsp;cm; avoid dosing in the evening; discuss BP home monitoring with your doctor.<\/p>\n<h2 class=\"wp-block-heading\">Monitoring on Floricot<\/h2>\n<ul>\n<li>Supine and standing blood pressure (target: standing BP &ge; 90\/60 mmHg without severe supine hypertension)<\/li>\n<li>Serum potassium (should stay 3.5&ndash;5.0 mmol\/L)<\/li>\n<li>Serum sodium<\/li>\n<li>Body weight and ankle oedema<\/li>\n<li>In Addison&#8217;s disease: plasma renin (low plasma renin suggests over-replacement)<\/li>\n<li>Long-term: bone density, glucose tolerance, cataracts<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Objedn\u00e1vky a dod\u00e1n\u00ed<\/h2>\n<p>MedsBase nab\u00edz\u00ed celosv\u011btovou dopravu pro ka\u017edou objedn\u00e1vku. Objedn\u00e1vky jsou odes\u00edl\u00e1ny v diskr\u00e9tn\u00edch obalech a dod\u00e1v\u00e1ny v origin\u00e1ln\u00edch v\u00fdrobn\u00edch balen\u00edch. Pokud je po\u017eadovan\u00e1 s\u00edla nebo velikost balen\u00ed nedostupn\u00e1, kontaktujte z\u00e1kaznickou podporu pro odhad dodac\u00ed lh\u016fty.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:20px 0;border-radius:4px;\">\n<p style=\"margin:0;\"><strong>Zdravotn\u00ed prohl\u00e1\u0161en\u00ed.<\/strong> Informace na t\u00e9to str\u00e1nce slou\u017e\u00ed pouze pro obecn\u00e9 vzd\u011bl\u00e1vac\u00ed \u00fa\u010dely. Nejsou n\u00e1hradou za rady va\u0161eho l\u00e9ka\u0159e nebo l\u00e9k\u00e1rn\u00edka. P\u0159ed zah\u00e1jen\u00edm, ukon\u010den\u00edm nebo zm\u011bnou l\u00e9\u010dby se pora\u010fte s kvalifikovan\u00fdm zdravotnick\u00fdm pracovn\u00edkem.<\/p>\n<\/div>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3 class=\"wp-block-heading\">What is Floricot used for?<\/h3>\n<p>Floricot (fludrocortisone 100 mcg) is used for mineralocorticoid replacement in primary adrenal insufficiency (Addison&#8217;s disease) and congenital adrenal hyperplasia, and for the treatment of severe neurogenic orthostatic hypotension and postural orthostatic tachycardia syndrome.<\/p>\n<h3 class=\"wp-block-heading\">Is Floricot a blood-pressure medicine?<\/h3>\n<p>Not in the usual sense &mdash; it raises blood pressure by promoting salt and water retention. It is used in patients who faint or feel dizzy on standing (orthostatic hypotension), not in patients with high blood pressure. For essential hypertension, entirely different classes are used.<\/p>\n<h3 class=\"wp-block-heading\">Why must I take Floricot for life if I have Addison&#8217;s disease?<\/h3>\n<p>In Addison&#8217;s disease, the adrenal glands cannot produce enough aldosterone. Without mineralocorticoid replacement, sodium, water, and blood pressure fall, and potassium rises &mdash; progressing to potentially fatal Addisonian crisis. Fludrocortisone replaces what your body cannot make; lifelong therapy is essential, exactly like insulin for type 1 diabetes.<\/p>\n<h3 class=\"wp-block-heading\">How long does Floricot take to work?<\/h3>\n<p>The first dose raises plasma volume within hours and improves orthostatic symptoms within 1&ndash;3 days. Full effect on standing blood pressure is usually seen within 1&ndash;2 weeks, as blood volume equilibrates at the new steady state.<\/p>\n<h3 class=\"wp-block-heading\">Will Floricot make me gain weight?<\/h3>\n<p>Some weight gain from fluid retention is normal, particularly in the first 2&ndash;4 weeks. Rapid weight gain (&gt; 2 kg in a week), ankle swelling, or shortness of breath may mean the dose is too high &mdash; contact your doctor.<\/p>\n<h3 class=\"wp-block-heading\">Why am I getting muscle cramps on Floricot?<\/h3>\n<p>Cramps and weakness usually reflect low blood potassium (hypokalaemia). Fludrocortisone promotes potassium loss in the urine. If cramps are persistent, your doctor will check your electrolytes and may recommend a potassium-rich diet or supplement.<\/p>\n<h3 class=\"wp-block-heading\">Can I stop Floricot suddenly?<\/h3>\n<p>No &mdash; particularly not in adrenal insufficiency. Abrupt withdrawal can trigger a life-threatening Addisonian crisis. Any dose change must be gradual and under specialist supervision.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Floricot in pregnancy?<\/h3>\n<p>In adrenal insufficiency, yes &mdash; continuation of fludrocortisone through pregnancy is essential. Dose adjustments may be needed, particularly in the second and third trimesters, under endocrinology supervision.<\/p>\n<h3 class=\"wp-block-heading\">What happens if my blood pressure gets too high on Floricot?<\/h3>\n<p>This is a known dose-related effect. Your doctor will check supine and standing blood pressure at each visit. If supine BP exceeds 160\/100 or you develop symptoms of heart failure, the dose will be reduced. Elevating the head of the bed at night and avoiding evening dosing can help.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Floricot with other blood-pressure medications?<\/h3>\n<p>Yes, but carefully. In adrenal insufficiency, antihypertensives are rarely needed. For orthostatic hypotension, fludrocortisone is sometimes combined with midodrine (a direct vasoconstrictor); the combination is effective but requires close BP monitoring.<\/p>\n<h3 class=\"wp-block-heading\">Is Floricot a steroid?<\/h3>\n<p>Yes &mdash; fludrocortisone is a synthetic steroid with strong mineralocorticoid activity and weak glucocorticoid activity. It is not the same as anti-inflammatory steroids like prednisolone or dexamethasone &mdash; fludrocortisone is primarily a salt-retaining hormone replacement.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Souvisej\u00edc\u00ed alternativy<\/h3>\n<p>Dal\u0161\u00ed produkty v <strong>Chronick\u00e1 onemocn\u011bn\u00ed<\/strong> kter\u00e9 z\u00e1kazn\u00edci tak\u00e9 prohl\u00ed\u017eej\u00ed:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/erythego-gel\/\">Erythego Gel<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/janumet\/\">Janumet<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/losatec-h\/\">Losatec H<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/levolin-inhaler\/\">Levolin Inhaler<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/rozucor\/\">Sim Hdl<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<div class=\"react-scroll-to-bottom--css-wbamh-1n7m0yu\">\n<div class=\"flex flex-col pb-9 text-sm\">\n<div class=\"w-full text-token-text-primary sm:AIPRM__conversation__response\" data-testid=\"conversation-turn-113\">\n<div class=\"px-4 py-2 justify-center text-base md:gap-6 m-auto\">\n<div class=\"flex flex-1 text-base mx-auto gap-3 md:px-5 lg:px-1 xl:px-5 md:max-w-3xl lg:max-w-[40rem] xl:max-w-[48rem] group final-completion\">\n<div class=\"relative flex w-full flex-col lg:w-[calc(100%-115px)] agent-turn\">\n<div class=\"flex-col gap-1 md:gap-3\">\n<div class=\"flex flex-grow flex-col max-w-full\">\n<div class=\"min-h-[20px] text-message flex flex-col items-start gap-3 whitespace-pre-wrap break-words [.text-message+&amp;]:mt-5 overflow-x-auto\" data-message-author-role=\"assistant\" data-message-id=\"a0d792e0-c2b2-480b-bb66-f9897fbd36ae\">\n<div class=\"markdown prose w-full break-words dark:prose-invert light AIPRM__conversation__response\">\n<p>\u2705 Manages Adrenal Insufficiency<br \/>\n\u2705 Regulates Blood Pressure<br \/>\n\u2705 Improves Salt Retention<br \/>\n\u2705 Treats Orthostatic Hypotension<br \/>\n\u2705 Enhances Electrolyte Balance<\/p>\n<p>Floricot contains Fludrocortisone.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"featured_media":57093,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3260],"product_tag":[4229,4230],"class_list":{"0":"post-57092","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-heart-blood-pressure","9":"product_tag-floricot","10":"product_tag-fludrocortisone","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/57092","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=57092"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/57093"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=57092"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=57092"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=57092"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=57092"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}