{"id":57525,"date":"2024-02-27T17:48:32","date_gmt":"2024-02-27T17:48:32","guid":{"rendered":"https:\/\/medsname.com\/hydrocort-100-injection\/"},"modified":"2026-05-01T10:49:14","modified_gmt":"2026-05-01T10:49:14","slug":"hydrocort-100-injection","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/hydrocort-100-injection\/","title":{"rendered":"Injekce Hydrocort 100"},"content":{"rendered":"

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⚡ Quick Answer — What is Hydrocort 100 Injection?<\/h3>\n

Injekce Hydrocort 100<\/strong> je hydrocortisone sodium succinate 100 mg per vial<\/strong> sterile powder for reconstitution, used for intravenous or intramuscular injection<\/strong>. It is the standard parenteral glucocorticoid for acute allergic reactions, anaphylaxis, adrenal crisis, acute severe asthma, severe inflammatory disease, shock, and as short-term cover in adrenal insufficiency<\/strong>. Obvykl\u00e1 d\u00e1vka pro dosp\u011bl\u00e9 je 100 mg IV\/IM every 6 hours<\/strong> in acute settings, adjusted for the clinical scenario.<\/p>\n<\/div>\n

\nCo z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n

\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n

Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n

Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n

Injekce Hydrocort 100<\/strong> is a sterile powder containing hydrocortisone sodium succinate<\/strong>, the water-soluble ester of hydrocortisone that can be reconstituted for rapid intravenous or intramuscular administration. Hydrocortisone is the synthetic form of cortisol<\/em>, the natural glucocorticoid produced by the adrenal cortex.<\/p>\n

Because parenteral hydrocortisone acts within minutes when given IV, it is the default glucocorticoid of choice in emergency settings where rapid glucocorticoid effect is required — anaphylaxis, acute severe asthma, shock in adrenal insufficiency, and severe inflammatory or allergic reactions. The 100 mg vial strength is the most commonly used in adults.<\/p>\n

What Is Hydrocort 100 Injection Used For?<\/h2>\n
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  • Acute adrenal crisis<\/strong> (Addisonian crisis) — life-threatening cortisol deficiency<\/li>\n
  • Anaphylaxis<\/strong> — as second-line to adrenaline; reduces the late-phase response<\/li>\n
  • Akutn\u00ed t\u011b\u017ek\u00e9 astma<\/strong> — when oral prednisolone is not possible (patient too unwell, vomiting)<\/li>\n
  • Acute exacerbations of chronic inflammatory disease<\/strong> — inflammatory bowel disease, autoimmune rheumatic disease<\/li>\n
  • T\u011b\u017ek\u00e9 alergick\u00e9 reakce<\/strong> — drug allergy, angioedema, serum sickness<\/li>\n
  • Septic shock<\/strong> with suspected adrenal insufficiency (specialist use in ICU)<\/li>\n
  • Stress-dose cover<\/strong> for patients on long-term oral steroids undergoing surgery or severe illness<\/li>\n
  • Thyrotoxic crisis<\/strong> — as adjunct<\/li>\n
  • Cerebral oedema<\/strong> — though dexamethasone is usually preferred<\/li>\n
  • Transfusion reactions<\/strong>, severe reactions to chemotherapy or contrast media<\/li>\n<\/ul>\n

    How Does Hydrocortisone Work?<\/h2>\n

    Hydrocortisone binds to intracellular glucocorticoid receptors, translocates to the nucleus, and modulates transcription of hundreds of genes. The net effect is broad:<\/p>\n

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    • Protiz\u00e1n\u011btliv\u00fd \u00fa\u010dinek<\/strong> — reduces cytokine production, leukocyte trafficking, and vascular permeability<\/li>\n
    • Immunosuppressive<\/strong> — suppresses T-cell activation, antibody production, and inflammatory cell function<\/li>\n
    • Metabolic<\/strong> — raises blood glucose, promotes protein catabolism, shifts fat distribution<\/li>\n
    • Mineralocorticoid activity<\/strong> — hydrocortisone has substantial salt-retaining action (unlike dexamethasone), which is useful in adrenal insufficiency but can cause fluid retention and hypertension at high doses<\/li>\n<\/ul>\n

      Hydrocort 100 Injection Dosing<\/h2>\n
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      • Adult acute inflammatory \/ anaphylactic \/ asthma:<\/strong> 100–200 mg IV\/IM, repeated at 2–6 hour intervals as required<\/li>\n
      • Acute adrenal crisis:<\/strong> 100 mg IV bolus, then 100 mg every 6 hours by slow IV infusion until oral therapy tolerated<\/li>\n
      • Peri-operative stress cover<\/strong> for patients on long-term steroids: 100 mg IV pre-induction, then 100 mg every 6 hours for the first 24–48 hours<\/li>\n
      • D\u011bti:<\/strong> weight- and age-based; typically 2–4 mg\/kg per dose IV\/IM, every 6 hours (specialist paediatric care)<\/li>\n<\/ul>\n

        Reconstitute the vial immediately before use with 2 mL of water for injection; inspect for particulate matter before administration. IV push should be given over at least 30 seconds for the 100 mg dose; larger doses should be given over 10 minutes or diluted for infusion.<\/p>\n

        Corticosteroid Potency and Equivalence<\/h2>\n

        Different corticosteroids differ mainly in potency, duration of action, and mineralocorticoid (salt-retaining) activity. The table below gives the clinically useful equivalence — it lets you translate a dose of one steroid into the equivalent dose of another.<\/p>\n\n\n\n\n\n\n\n\n\n
        Corticosteroid<\/th>\nGlucocorticoid potency<\/th>\nEquivalent dose<\/th>\nMineralocorticoid<\/th>\nD\u00e9lka<\/th>\n<\/tr>\n<\/thead>\n
        Hydrocortisone<\/td>\n1 (reference)<\/td>\n20 mg<\/td>\nSubstantial<\/td>\n8–12 h<\/td>\n<\/tr>\n
        Prednisolone<\/td>\n4<\/td>\n5 mg<\/td>\nN\u00edzk\u00e1<\/td>\n12–36 h<\/td>\n<\/tr>\n
        Methylprednisolon<\/td>\n5<\/td>\n4 mg<\/td>\nMinim\u00e1ln\u00ed<\/td>\n12–36 h<\/td>\n<\/tr>\n
        Dexamethasone<\/strong><\/td>\n25–30<\/td>\n0.75 mg<\/td>\n\u017d\u00e1dn\u00e9<\/td>\n36–54 h<\/td>\n<\/tr>\n
        Betamethason<\/td>\n25–30<\/td>\n0.75 mg<\/td>\n\u017d\u00e1dn\u00e9<\/td>\n36–54 h<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

        Who Should Not Take Hydrocort 100 Injection?<\/h2>\n