<\/p>\n
Inmecin-R<\/strong> je 75 mg kapsle s prodlou\u017een\u00fdm uvol\u0148ov\u00e1n\u00edm indomethacinu<\/strong>, pohodln\u00e1 jednou nebo dvakr\u00e1t denn\u011b pod\u00e1van\u00e1 forma jednoho z nej\u00fa\u010dinn\u011bj\u0161\u00edch neselektivn\u00edch NSAID pou\u017e\u00edvan\u00fdch v klinick\u00e9 praxi. Pou\u017e\u00edv\u00e1 se pro chronick\u00e1 z\u00e1n\u011btliv\u00e1 artritida<\/strong>, zejm\u00e9na revmatoidn\u00ed artritida, ankylozuj\u00edc\u00ed spondylitida a dlouhodob\u00e1 l\u00e9\u010dba dny. Obvykl\u00e1 d\u00e1vka pro dosp\u011bl\u00e9 je jedna 75 mg SR tobolka jednou nebo dvakr\u00e1t denn\u011b s j\u00eddlem<\/strong>. Indomethacin m\u00e1 siln\u011bj\u0161\u00ed \u00fa\u010dinky na CNS a GIT ne\u017e ibuprofen \u2014 pou\u017e\u00edvejte nejni\u017e\u0161\u00ed \u00fa\u010dinnou d\u00e1vku po nejkrat\u0161\u00ed rozumnou dobu.<\/p>\n<\/div>\n \ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n Inmecin-R 75 mg<\/strong> je tobolka s prodlou\u017een\u00fdm uvol\u0148ov\u00e1n\u00edm (SR) obsahuj\u00edc\u00ed indomethacin<\/strong>. Formulace SR rozkl\u00e1d\u00e1 uvol\u0148ov\u00e1n\u00ed 75 mg d\u00e1vky b\u011bhem 8\u201312 hodin, co\u017e poskytuje stabiln\u011bj\u0161\u00ed hladiny v krvi a jednodu\u0161\u0161\u00ed d\u00e1vkov\u00e1n\u00ed jednou nebo dvakr\u00e1t denn\u011b oproti tobolk\u00e1m s okam\u017eit\u00fdm uvol\u0148ov\u00e1n\u00edm 25\/50 mg (Inmecin), kter\u00e9 se mus\u00ed u\u017e\u00edvat t\u0159ikr\u00e1t denn\u011b.<\/p>\n Inmecin-R se obvykle vol\u00ed, kdy\u017e pacient pot\u0159ebuje dlouhodobou terapii indomethacinem pro z\u00e1n\u011btlivou spondyloartropatii, chronickou dnu nebo p\u0159etrv\u00e1vaj\u00edc\u00ed z\u00e1n\u011btlivou artritidu a dodr\u017eov\u00e1n\u00ed trojdenn\u00edho d\u00e1vkov\u00e1n\u00ed je obt\u00ed\u017en\u00e9. Celkov\u00e1 denn\u00ed d\u00e1vka 75\u2013150 mg je podobn\u00e1 jako u indomethacinu s okam\u017eit\u00fdm uvol\u0148ov\u00e1n\u00edm.<\/p>\n Indometacin je neselektivn\u00ed NSAID<\/strong> \u2014 blokuje jak COX-1<\/strong> (kter\u00fd udr\u017euje \u017ealude\u010dn\u00ed sliznici, funkci krevn\u00edch desti\u010dek a prokrven\u00ed ledvin), tak COX-2<\/strong> (kter\u00fd je zv\u00fd\u0161en\u011b exprimov\u00e1n v m\u00edstech z\u00e1n\u011btu). Toto \u0161irok\u00e9 p\u016fsoben\u00ed vysv\u011btluje jak jeho siln\u00fd protiz\u00e1n\u011btliv\u00fd \u00fa\u010dinek, tak jeho dob\u0159e zn\u00e1m\u00fd profil gastrointestin\u00e1ln\u00edch a ren\u00e1ln\u00edch ne\u017e\u00e1douc\u00edch \u00fa\u010dink\u016f.<\/p>\n Terapeutick\u00fd \u0159et\u011bzec ud\u00e1lost\u00ed je u v\u0161ech NSAID stejn\u00fd:<\/p>\n Proto\u017ee prostaglandiny tak\u00e9 chr\u00e1n\u00ed \u017ealude\u010dn\u00ed sliznici, reguluj\u00ed pr\u016ftok krve ledvinami a ovliv\u0148uj\u00ed funkci krevn\u00edch desti\u010dek, stejn\u00fd mechanismus, kter\u00fd zm\u00edr\u0148uje bolest, je tak\u00e9 zodpov\u011bdn\u00fd za hlavn\u00ed vedlej\u0161\u00ed \u00fa\u010dinky NSAID: podr\u00e1\u017ed\u011bn\u00ed \u017ealudku, zadr\u017eov\u00e1n\u00ed tekutin, vysok\u00fd krevn\u00ed tlak a (u n\u011bkter\u00fdch jedinc\u016f) z\u00e1t\u011b\u017e ledvin.<\/p>\n SR tobolku spolkn\u011bte celou s vodou, s j\u00eddlem nebo po j\u00eddle. Neotv\u00edrejte, nedr\u0165te ani ne\u017ev\u00fdkejte<\/strong> \u2014 to zni\u010d\u00ed prodlou\u017een\u00e9 uvol\u0148ov\u00e1n\u00ed a p\u0159em\u011bn\u00ed 12hodinovou d\u00e1vku na okam\u017eit\u00fd v\u00fdbuch, co\u017e zv\u00fd\u0161\u00ed riziko jak GI, tak CNS.<\/p>\n Jednor\u00e1zov\u00e1 denn\u00ed d\u00e1vka se obvykle u\u017e\u00edv\u00e1 r\u00e1no p\u0159i sn\u00eddani. Dvakr\u00e1t denn\u00ed d\u00e1vkov\u00e1n\u00ed by m\u011blo b\u00fdt rozlo\u017eeno p\u0159ibli\u017en\u011b 12 hodin od sebe (nap\u0159. v 8 r\u00e1no a v 8 ve\u010der, v\u017edy s j\u00eddlem).<\/p>\n GI bezpecnost \u2014 precist pred prvnim uzitim.<\/strong> Ka\u017ed\u00e9 NSAID, v\u010detn\u011b Inmecin-R, nese skute\u010dn\u00e9 riziko gastritidy, peptick\u00e9ho v\u0159edu a krv\u00e1cen\u00ed z horn\u00edho GI traktu. Riziko je nejvy\u0161\u0161\u00ed u pacient\u016f nad 65 let, u t\u011bch s p\u0159edchoz\u00edm v\u0159edov\u00fdm onemocn\u011bn\u00edm a u ka\u017ed\u00e9ho, kdo u\u017e\u00edv\u00e1 n\u00edzk\u00e9 d\u00e1vky aspirinu, kortikosteroid\u016f, SSRI nebo antikoagulanci\u00ed. U\u017e\u00edvejte Inmecin-R s j\u00eddlem<\/em>, pouzijte nejnizsi ucinnou davku po nejkratsi rozumne dlouhou dobu<\/em>, a zeptejte se lekare na predpis inhibitoru protonove pumpy (omeprazol, pantoprazol), pokud ho potrebujete dele nez 2\u20134 tydny.<\/p>\n<\/div>\n Specifick\u00e1 upozorn\u011bn\u00ed pro indometacin:<\/strong><\/p>\n V\u0161echna NSAID (krom\u011b n\u00edzk\u00fdch d\u00e1vek aspirinu) nesou ur\u010dit\u00e9 zv\u00fd\u0161en\u00ed rizika infarktu a mrtvice a mohou zhor\u0161it srde\u010dn\u00ed selh\u00e1n\u00ed. Riziko je z\u00e1visl\u00e9 na d\u00e1vce a d\u00e9lce u\u017e\u00edv\u00e1n\u00ed a je obecn\u011b nejvy\u0161\u0161\u00ed u COX-2 selektivn\u00edch l\u00e1tek a u diklofenaku. Pacienti s prok\u00e1zan\u00fdm ischemick\u00fdm onemocn\u011bn\u00edm srdce, perifern\u00edm arteri\u00e1ln\u00edm onemocn\u011bn\u00edm, mrtvic\u00ed nebo nekontrolovanou hypertenz\u00ed by m\u011bli pou\u017e\u00edvat neselektivn\u00ed NSAID (ibuprofen nebo naproxen) v nejni\u017e\u0161\u00ed \u00fa\u010dinn\u00e9 d\u00e1vce, nebo pokud mo\u017eno m\u00edsto nich paracetamol.<\/p>\n NSAID sni\u017euj\u00ed produkci ren\u00e1ln\u00edch prostaglandin\u016f, co\u017e m\u016f\u017ee zp\u016fsobit zadr\u017eov\u00e1n\u00ed sol\u00ed a vody, zv\u00fd\u0161en\u00ed krevn\u00edho tlaku a \u2013 u zraniteln\u00fdch pacient\u016f \u2013 akutn\u00ed po\u0161kozen\u00ed ledvin. Mezi vysoce rizikov\u00e9 skupiny pat\u0159\u00ed star\u0161\u00ed pacienti, pacienti u\u017e\u00edvaj\u00edc\u00ed ACE inhibitory\/ARB spolu s diuretiky (tzv. \u201ctrojit\u00fd z\u00e1sah\u201d), dehydratovan\u00ed jedinci (zvracen\u00ed, pr\u016fjem, horko, intenzivn\u00ed cvi\u010den\u00ed) a pacienti s ji\u017e existuj\u00edc\u00edm CKD. P\u0159esta\u0148te u\u017e\u00edvat NSAID a vyhledejte l\u00e9ka\u0159skou kontrolu, pokud se u v\u00e1s objev\u00ed sn\u00ed\u017een\u00fd v\u00fddej mo\u010di, otoky nebo nevysv\u011btlen\u00fd p\u0159\u00edr\u016fstek hmotnosti.<\/p>\n SR forma neeliminuje charakteristick\u00e9 ne\u017e\u00e1douc\u00ed \u00fa\u010dinky indometacinu \u2014 vyrovn\u00e1v\u00e1 plazmatick\u00e9 vrcholy, ale celkov\u00e1 denn\u00ed expozice je podobn\u00e1.<\/p>\n MedsBase nab\u00edz\u00ed celosv\u011btovou dopravu pro ka\u017edou objedn\u00e1vku. Objedn\u00e1vky jsou odes\u00edl\u00e1ny v diskr\u00e9tn\u00edch obalech a dod\u00e1v\u00e1ny v origin\u00e1ln\u00edch v\u00fdrobn\u00edch balen\u00edch. Pokud je po\u017eadovan\u00e1 s\u00edla nebo velikost balen\u00ed nedostupn\u00e1, kontaktujte z\u00e1kaznickou podporu pro odhad dodac\u00ed lh\u016fty.<\/p>\n Zdravotn\u00ed prohl\u00e1\u0161en\u00ed.<\/strong> Informace na t\u00e9to str\u00e1nce slou\u017e\u00ed pouze pro obecn\u00e9 vzd\u011bl\u00e1v\u00e1n\u00ed. Nejsou n\u00e1hradou za rady va\u0161eho l\u00e9ka\u0159e nebo l\u00e9k\u00e1rn\u00edka. NSAID maj\u00ed dob\u0159e zdokumentovan\u00e1 gastrointestin\u00e1ln\u00ed, kardiovaskul\u00e1rn\u00ed a ren\u00e1ln\u00ed rizika \u2013 p\u0159ed zah\u00e1jen\u00edm, ukon\u010den\u00edm nebo zm\u011bnou l\u00e9\u010dby se pora\u010fte s kvalifikovan\u00fdm zdravotnick\u00fdm pracovn\u00edkem, zejm\u00e9na pokud m\u00e1te v anamn\u00e9ze peptick\u00fd v\u0159ed, srde\u010dn\u00ed onemocn\u011bn\u00ed, onemocn\u011bn\u00ed ledvin, astma nebo jste t\u011bhotn\u00e1.<\/p>\n<\/div>\n Inmecin-R (indomethacin 75 mg SR) se pou\u017e\u00edv\u00e1 u chronick\u00fdch z\u00e1n\u011btliv\u00fdch stav\u016f \u2014 revmatoidn\u00ed artritida, ankylozuj\u00edc\u00ed spondylitida, psoriatick\u00e1 artritida, osteoartritida s v\u00fdrazn\u00fdm z\u00e1n\u011btem a udr\u017eovac\u00ed l\u00e9\u010dba chronick\u00e9 dny.<\/p>\n Stejn\u00e1 molekula (indomethacin), jin\u00e1 forma. Inmecin-R 75 mg je s prodlou\u017een\u00fdm uvol\u0148ov\u00e1n\u00edm, pod\u00e1v\u00e1 se jednou nebo dvakr\u00e1t denn\u011b. Inmecin 25\/50 mg je s okam\u017eit\u00fdm uvol\u0148ov\u00e1n\u00edm, pod\u00e1v\u00e1 se t\u0159ikr\u00e1t denn\u011b. SR forma je pohodln\u011bj\u0161\u00ed pro chronickou terapii.<\/p>\n Indomethacin je l\u00e9kem prvn\u00ed volby pro akutn\u00ed dnu, ale s okam\u017eit\u00fdm uvol\u0148ov\u00e1n\u00edm<\/em> forma (Inmecin 50 mg TDS) je obvykle up\u0159ednost\u0148ov\u00e1na pro rychlou kontrolu p\u0159\u00edznak\u016f b\u011bhem prvn\u00edch 48\u201372 hodin. Inmecin-R je vhodn\u011bj\u0161\u00ed pro udr\u017eovac\u00ed l\u00e9\u010dbu chronick\u00e9 dny nebo v p\u0159\u00edpad\u011b, \u017ee pacient ji\u017e u\u017e\u00edv\u00e1 terapii SR.<\/p>\n Ne. Pelety s prodlou\u017een\u00fdm uvol\u0148ov\u00e1n\u00edm uvnit\u0159 tobolky spol\u00e9haj\u00ed na neporu\u0161en\u00fd obal, aby se uvol\u0148ovaly postupn\u011b. Otev\u0159en\u00ed, rozdrcen\u00ed nebo rozkous\u00e1n\u00ed zp\u016fsob\u00ed okam\u017eit\u00e9 uvoln\u011bn\u00ed cel\u00e9 d\u00e1vky 75 mg, co\u017e v\u00fdrazn\u011b zvy\u0161uje riziko ne\u017e\u00e1douc\u00edch \u00fa\u010dink\u016f.<\/p>\n \u00daleva od bolesti obvykle nastupuje b\u011bhem 1\u20132 hodin po prvn\u00ed d\u00e1vce; maxim\u00e1ln\u00ed protiz\u00e1n\u011btliv\u00fd \u00fa\u010dinek se rozv\u00edj\u00ed b\u011bhem 1\u20132 t\u00fddn\u016f pravideln\u00e9ho u\u017e\u00edv\u00e1n\u00ed.<\/p>\n Always take it with food or milk. Never on an empty stomach \u2014 gastric irritation is the most common reason patients drop out.<\/p>\n P\u0159i ankylozuj\u00edc\u00ed spondylitid\u011b m\u016f\u017ee pravideln\u00e1 l\u00e9\u010dba NSAID (v\u010detn\u011b indometacinu SR) zpomalit radiografickou progresi. Dlouhodob\u00e9 u\u017e\u00edv\u00e1n\u00ed by m\u011blo b\u00fdt spojeno s inhibitorem protonov\u00e9 pumpy pro ochranu GI traktu a pravideln\u00e9 sledov\u00e1n\u00ed krevn\u00edho tlaku, funkce ledvin a jatern\u00edch enzym\u016f.<\/p>\n Vyhn\u011bte se alkoholu nebo jej omezte na ob\u010dasn\u00e9 lehk\u00e9 u\u017e\u00edv\u00e1n\u00ed. Alkohol zvy\u0161uje riziko krv\u00e1cen\u00ed do GI traktu u jak\u00e9hokoli NSAID a m\u016f\u017ee zhor\u0161it z\u00e1vrat\u011b a ospalost.<\/p>\n Ne \u2014 kontraindikov\u00e1n ve t\u0159et\u00edm trimestru (riziko p\u0159ed\u010dasn\u00e9ho uzav\u0159en\u00ed ductus arteriosus). Vyhn\u011bte se u\u017e\u00edv\u00e1n\u00ed v \u010dasn\u00e9m t\u011bhotenstv\u00ed, pokud nen\u00ed pod speci\u00e1ln\u00edm dohledem.<\/p>\n Lithium (zv\u00fd\u0161en\u00ed hladin), methotrex\u00e1t (toxicita), ACE inhibitory + diuretika (po\u0161kozen\u00ed ledvin), antikoagulancia a SSRI (riziko krv\u00e1cen\u00ed), antihypertenziva (sn\u00ed\u017een\u00ed \u00fa\u010dinku na krevn\u00ed tlak). Sd\u00edlejte sv\u016fj \u00fapln\u00fd seznam l\u00e9k\u016f s p\u0159edepisuj\u00edc\u00edm l\u00e9ka\u0159em.<\/p>\n Nejprve otestujte svou reakci. Z\u00e1vrat\u011b nebo ospalost jsou b\u011b\u017en\u00e9 v prvn\u00edch n\u011bkolika dnech; ne\u0159i\u010fte, dokud nev\u00edte, jak na v\u00e1s l\u00e9k p\u016fsob\u00ed.<\/p>\n <\/p>\n Dal\u0161\u00ed produkty v Chronick\u00e1 onemocn\u011bn\u00ed<\/strong> kter\u00e9 z\u00e1kazn\u00edci tak\u00e9 prohl\u00ed\u017eej\u00ed:<\/p>\n \u2705 Zm\u00edr\u0148uje z\u00e1n\u011bt Inmecin-R obsahuje Indomethacin.<\/p>","protected":false},"featured_media":57613,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3920,3555],"product_tag":[4335,4336],"class_list":{"0":"post-57612","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-gout-treatment","9":"product_cat-pain-relief-medication","10":"product_tag-indomethacin","11":"product_tag-inmecin-r","13":"first","14":"instock","15":"shipping-taxable","16":"purchasable","17":"product-type-variable","18":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/57612","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=57612"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/57613"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=57612"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=57612"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=57612"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=57612"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n
K \u010demu se Inmecin-R pou\u017e\u00edv\u00e1?<\/h2>\n
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Jak funguje indometacin?<\/h2>\n
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D\u00e1vkov\u00e1n\u00ed Inmecin-R<\/h2>\n
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Kdo by nem\u011bl u\u017e\u00edvat Inmecin-R?<\/h2>\n
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Kardiovaskul\u00e1rn\u00ed riziko<\/h3>\n
Ren\u00e1ln\u00ed (ledvinov\u00e1) bezpe\u010dnost<\/h3>\n
Ne\u017e\u00e1douc\u00ed \u00fa\u010dinky Inmecin-R<\/h2>\n
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Objedn\u00e1vky a dod\u00e1n\u00ed<\/h2>\n
\u010casto kladen\u00e9 dotazy<\/h2>\n
K \u010demu se Inmecin-R pou\u017e\u00edv\u00e1?<\/h3>\n
Jak\u00fd je rozd\u00edl mezi Inmecin-R a Inmecin?<\/h3>\n
Je Inmecin-R vhodn\u00fd pro akutn\u00ed z\u00e1chvaty dny?<\/h3>\n
Mohu otev\u0159\u00edt kapsli Inmecin-R?<\/h3>\n
Jak dlouho trv\u00e1, ne\u017e Inmecin-R za\u010dne \u00fa\u010dinkovat?<\/h3>\n
Mohu u\u017e\u00edvat Inmecin-R s j\u00eddlem?<\/h3>\n
Je Inmecin-R bezpe\u010dn\u00fd pro dlouhodob\u00e9 u\u017e\u00edv\u00e1n\u00ed?<\/h3>\n
Mohu p\u00edt alkohol p\u0159i u\u017e\u00edv\u00e1n\u00ed Inmecin-R?<\/h3>\n
Je Inmecin-R bezpe\u010dn\u00fd v t\u011bhotenstv\u00ed?<\/h3>\n
Na jak\u00e9 l\u00e9kov\u00e9 interakce bych si m\u011bl d\u00e1t pozor?<\/h3>\n
Mohu \u0159\u00eddit p\u0159i u\u017e\u00edv\u00e1n\u00ed Inmecin-R?<\/h3>\n
Souvisej\u00edc\u00ed alternativy<\/h3>\n
\n
\n\u2705 Zm\u00edr\u0148uje bolest
\n\u2705 Sni\u017euje otok
\n\u2705 L\u00e9\u010d\u00ed artritidu
\n\u2705 Zvl\u00e1d\u00e1 dnu<\/p>\n