{"id":57860,"date":"2024-02-27T18:05:01","date_gmt":"2024-02-27T18:05:01","guid":{"rendered":"https:\/\/medsname.com\/ketorol-dt\/"},"modified":"2026-05-01T10:49:14","modified_gmt":"2026-05-01T10:49:14","slug":"ketorol-dt","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/ketorol-dt\/","title":{"rendered":"Ketorol DT"},"content":{"rendered":"

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⚡ Quick Answer — What is Ketorol DT?<\/h3>\n

Ketorol DT<\/strong> je ketorolac tromethamine 10 mg orally disintegrating tablet<\/strong> po dobu short-term<\/strong> relief of moderate to severe acute pain. Ketorolac is unusually potent for an oral NSAID and is often used as a non-opioid analgesic<\/strong> after surgery, dental procedures, renal colic, or significant soft-tissue injury. Usual dose: 10 mg every 4–6 hours with food, for a maximum of 5 days<\/strong>. Because of GI and renal risk, ketorolac is never used chronically<\/strong> — this is a short-course medicine only.<\/p>\n<\/div>\n

\nCo z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n

\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n

Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n

Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n

Ketorol DT<\/strong> is an orally disintegrating tablet (DT) containing ketorolac tromethamine 10 mg<\/strong> — the only NSAID in the world labelled solely for short-term, strong pain relief. Ketorolac’s analgesic potency is comparable to low-dose morphine for moderate pain, which has given it a particular role in post-operative, post-dental, and renal-colic care where strong analgesia is needed without the sedation, respiratory depression, or addiction risk of opioids.<\/p>\n

The orally disintegrating format dissolves on the tongue within seconds, making it useful when swallowing tablets is difficult — post-operative nausea, recent dental surgery, or heavy vomiting.<\/p>\n

What Is Ketorol DT Used For?<\/h2>\n
    \n
  • Short-term management of moderate to severe acute pain<\/strong> — post-operative, post-partum, post-dental<\/li>\n
  • Ledvinov\u00e1 kolika<\/strong> (kidney stone pain) — ketorolac is as effective as parenteral opioids in many studies<\/li>\n
  • Biliary colic<\/strong><\/li>\n
  • Akutn\u00ed poran\u011bn\u00ed pohybov\u00e9ho apar\u00e1tu<\/strong> — severe soft-tissue trauma<\/li>\n
  • Prim\u00e1rn\u00ed dysmenorea<\/strong> — severe period pain unresponsive to first-line NSAIDs<\/li>\n
  • Acute migraine<\/strong> — second-line; particularly when triptans are contraindicated<\/li>\n<\/ul>\n

    Ketorolac is not indicated for minor or chronic pain<\/strong>. Using it for conditions where paracetamol or ibuprofen would be adequate unnecessarily exposes the patient to GI and renal risk.<\/p>\n

    How Does Ketorolac Work?<\/h2>\n

    Ketorolac is a neselektivn\u00ed NSAID<\/strong> \u2014 blokuje jak COX-1<\/strong> (kter\u00fd udr\u017euje \u017ealude\u010dn\u00ed sliznici, funkci krevn\u00edch desti\u010dek a prokrven\u00ed ledvin), tak COX-2<\/strong> (kter\u00fd je zv\u00fd\u0161en\u011b exprimov\u00e1n v m\u00edstech z\u00e1n\u011btu). Toto \u0161irok\u00e9 p\u016fsoben\u00ed vysv\u011btluje jak jeho siln\u00fd protiz\u00e1n\u011btliv\u00fd \u00fa\u010dinek, tak jeho dob\u0159e zn\u00e1m\u00fd profil gastrointestin\u00e1ln\u00edch a ren\u00e1ln\u00edch ne\u017e\u00e1douc\u00edch \u00fa\u010dink\u016f.<\/p>\n

    Terapeutick\u00fd \u0159et\u011bzec ud\u00e1lost\u00ed je u v\u0161ech NSAID stejn\u00fd:<\/p>\n

      \n
    1. Po\u0161kozen\u00ed tk\u00e1n\u011b nebo z\u00e1n\u011bt uvol\u0148uje fosfolipidy z bun\u011b\u010dn\u00fdch membr\u00e1n<\/li>\n
    2. Fosfolip\u00e1za A\u2082 je p\u0159em\u011b\u0148uje na kyselinu arachidonovou<\/li>\n
    3. Cyklooxygen\u00e1za (COX-1\/COX-2) p\u0159em\u011b\u0148uje kyselinu arachidonovou na prostaglandiny<\/strong> \u2014 molekuly zodpov\u011bdn\u00e9 za bolest, otok a hore\u010dku<\/li>\n
    4. Ketorolac blocks the COX enzymes, so less prostaglandin is produced, so there is less pain and inflammation<\/li>\n<\/ol>\n

      Proto\u017ee prostaglandiny tak\u00e9 chr\u00e1n\u00ed \u017ealude\u010dn\u00ed sliznici, reguluj\u00ed pr\u016ftok krve ledvinami a ovliv\u0148uj\u00ed funkci krevn\u00edch desti\u010dek, stejn\u00fd mechanismus, kter\u00fd zm\u00edr\u0148uje bolest, je tak\u00e9 zodpov\u011bdn\u00fd za hlavn\u00ed vedlej\u0161\u00ed \u00fa\u010dinky NSAID: podr\u00e1\u017ed\u011bn\u00ed \u017ealudku, zadr\u017eov\u00e1n\u00ed tekutin, vysok\u00fd krevn\u00ed tlak a (u n\u011bkter\u00fdch jedinc\u016f) z\u00e1t\u011b\u017e ledvin.<\/p>\n

      Ketorol DT Dosing<\/h2>\n
        \n
      • Peror\u00e1ln\u011b:<\/strong> 10 mg every 4–6 hours as needed, maximum 40 mg\/day<\/li>\n
      • Maximum total duration (all routes combined):<\/strong> 5 dn\u00ed<\/li>\n
      • Elderly (> 65), body weight < 50 kg, or mild renal impairment:<\/strong> maximum 40 mg\/day and total duration ideally \u2264 2–3 days<\/li>\n<\/ul>\n

        Do not exceed 5 days of continuous ketorolac therapy<\/strong> in any form. The risk of GI ulcer and kidney injury rises sharply beyond this window. Transition to an alternative analgesic (ibuprofen, diclofenac, or paracetamol) after day 5.<\/p>\n

        Jak u\u017e\u00edvat:<\/strong> place the DT tablet on the tongue, allow it to disintegrate (5–15 seconds), swallow with saliva. No water needed. Take with food or milk when possible.<\/p>\n

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        GI bezpecnost \u2014 precist pred prvnim uzitim.<\/strong> Every NSAID, including Ketorol DT, carries a real risk of gastritis, peptic ulcer, and upper-GI bleeding. The risk is highest in patients over 65, in those with prior ulcer disease, and in anyone also taking low-dose aspirin, corticosteroids, SSRIs, or anticoagulants. Take Ketorol DT s j\u00eddlem<\/em>, pouzijte nejnizsi ucinnou davku po nejkratsi rozumne dlouhou dobu<\/em>, a zeptejte se lekare na predpis inhibitoru protonove pumpy (omeprazol, pantoprazol), pokud ho potrebujete dele nez 2\u20134 tydny.<\/p>\n<\/div>\n

        Ketorolac-specific warnings:<\/strong> Because ketorolac is unusually potent per milligram, it carries a higher rate of GI ulcers, bleeds, and acute kidney injury than most other oral NSAIDs at comparable pain-relief doses. This is why the 5-day limit exists and must be observed.<\/p>\n

        Who Should Not Take Ketorol DT?<\/h2>\n
          \n
        • Known hypersensitivity to Ketorolac or any NSAID<\/li>\n
        • Aktivn\u00ed nebo opakuj\u00edc\u00ed se peptick\u00fd v\u0159ed, krv\u00e1cen\u00ed nebo perforace tr\u00e1vic\u00edho traktu<\/li>\n
        • Astma, kop\u0159ivka nebo rinitida vyvolan\u00e1 aspirinem nebo jin\u00fdm NSAID (\u201caspirinem exacerbovan\u00e9 respira\u010dn\u00ed onemocn\u011bn\u00ed\u201d)<\/li>\n
        • T\u011b\u017ek\u00e9 srde\u010dn\u00ed selh\u00e1n\u00ed (NYHA t\u0159\u00edda IV)<\/li>\n
        • T\u011b\u017ek\u00e9 po\u0161kozen\u00ed jater (Child\u2013Pugh C)<\/li>\n
        • T\u011b\u017ek\u00e9 po\u0161kozen\u00ed ledvin (CrCl < 30 ml\/min)<\/li>\n
        • T\u0159et\u00ed trimestr t\u011bhotenstv\u00ed (riziko p\u0159ed\u010dasn\u00e9ho uzav\u0159en\u00ed ductus arteriosus a oligohydramnionu)<\/li>\n
        • Ned\u00e1vn\u00e1 operace koron\u00e1rn\u00edho bypassu (CABG) \u2014 absolutn\u00ed kontraindikace pro v\u0161echna NSAID<\/li>\n<\/ul>\n

          Ketorolac-specific:<\/strong><\/p>\n