{"id":57949,"date":"2024-02-27T18:09:12","date_gmt":"2024-02-27T18:09:12","guid":{"rendered":"https:\/\/medsname.com\/atarise\/"},"modified":"2026-04-30T10:24:19","modified_gmt":"2026-04-30T10:24:19","slug":"atarise","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/atarise\/","title":{"rendered":"Atarise"},"content":{"rendered":"

<\/p>\n

\n

\u26a1 Rychl\u00e1 odpov\u011b\u010f<\/h3>\n

Atarise (Hydroxyzine 10 \/ 25 mg) is a sedating first-generation antihistamine and centrally-acting anxiolytic. Used for short-term anxiety, pre-procedural sedation, allergic pruritus and urticaria, and as an antiemetic. Non-addictive \u2014 useful when benzodiazepines are inappropriate.<\/p>\n<\/div>\n

\nCo z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n

\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n

Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n

Atarise at MedsBase is supplied directly from a WHO-GMP certified manufacturer in plain, discreet packaging. Every order is covered by our Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/a> \u2014 20pracovn\u00edchdenn\u00ed lh\u016fta pro doru\u010den\u00ed, nebo v\u00e1m z\u00e1silku zdarma p\u0159epo\u0161leme \u2014 a oprav\u0148uje v\u00e1s k \u00fa\u010dasti v na\u0161em v\u011brnostn\u00edm programu<\/a>. Dod\u00e1v\u00e1me do v\u011bt\u0161iny zem\u00ed po cel\u00e9m sv\u011bt\u011b.<\/p>\n

What Atarise is and how it works<\/h2>\n

Atarise is a 10 \/ 25 mg hydroxyzine tablet supplied by Sun Pharma. Hydroxyzine is a piperazine first-generation antihistamine with strong central H1 antagonism, weak 5-HT2A antagonism, and modest anticholinergic activity. The H1 component crosses the blood-brain barrier well and is the basis for its sedating and anxiolytic effect.<\/p>\n

Hydroxyzine is one of the few non-benzodiazepine, non-barbiturate options for true PRN anxiety relief \u2014 onset within 30\u201360 minutes, duration 4\u20136 hours.<\/p>\n

Indikace a d\u00e1vkov\u00e1n\u00ed<\/h2>\n\n\n\n\n\n\n\n\n\n\n\n
Indikace<\/th>\nD\u00e1vkov\u00e1n\u00ed pro dosp\u011bl\u00e9<\/th>\nPozn\u00e1mky<\/th>\n<\/tr>\n<\/thead>\n
Acute anxiety \/ agitation<\/td>\n25\u2013100 mg PO\/IM, may repeat q6h<\/td>\nMax 400 mg\/day<\/td>\n<\/tr>\n
Pruritus \/ urticaria<\/td>\n25 mg TID\u2013QID<\/td>\nMax 100 mg QID<\/td>\n<\/tr>\n
Pre-operative sedation<\/td>\n50\u2013100 mg 1 hour pre-op<\/td>\n\u2014<\/td>\n<\/tr>\n
Antiemetic<\/td>\n25\u2013100 mg IM<\/td>\nAdults only<\/td>\n<\/tr>\n
Insomnia (off-label)<\/td>\n25\u201350 mg HS<\/td>\nShort-term only<\/td>\n<\/tr>\n
Paediatric pruritus \/ sedation<\/td>\n0.5\u20131 mg\/kg\/dose q6h<\/td>\n\u2014<\/td>\n<\/tr>\n
Older adults (any indication)<\/td>\nstart 10\u201325 mg<\/td>\nQT and falls risk<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

D\u016fle\u017eit\u00e9 bezpe\u010dnostn\u00ed aspekty<\/h2>\n
\nQT prolongation \u2014 2015 EMA restriction<\/strong><\/p>\n

Hydroxyzine prolongs QT in a dose-dependent manner. The EMA restricted dosing in 2015: maximum 100 mg\/day in adults, 50 mg\/day in older adults, and 2 mg\/kg\/day in children<\/strong>. Avoid in known QT prolongation, hypokalaemia\/hypomagnesaemia, recent MI, uncompensated heart failure, and concurrent QT-prolonging drugs (azoles, macrolides, fluoroquinolones, methadone, ondansetron, antipsychotics). Pre-treatment ECG advised in older adults.<\/p>\n<\/div>\n

\nAnticholinergic burden<\/strong><\/p>\n

Hydroxyzine has meaningful anticholinergic activity \u2014 particularly relevant in older adults (Beers Criteria potentially inappropriate medication). Avoid in narrow-angle glaucoma, BPH with retention, dementia, severe constipation. The American Geriatrics Society discourages first-generation antihistamines as PRN agents in older adults.<\/p>\n<\/div>\n

\nSedation and driving<\/strong><\/p>\n

Single-dose sedation can persist 6+ hours; avoid driving and operating machinery until tolerability is known. Particularly problematic in opioid-naive surgical patients on the day of discharge.<\/p>\n<\/div>\n

\u010cast\u00e9 ne\u017e\u00e1douc\u00ed \u00fa\u010dinky<\/h2>\n