{"id":58109,"date":"2024-02-27T18:17:49","date_gmt":"2024-02-27T18:17:49","guid":{"rendered":"https:\/\/medsname.com\/gamascab-lotion\/"},"modified":"2026-05-11T14:13:26","modified_gmt":"2026-05-11T14:13:26","slug":"gamascab-lotion","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/gamascab-lotion\/","title":{"rendered":"Gamascab Lotion"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:6px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:1.15em;\">\u26a1 Quick Answer \u2014 What is Gamascab Lotion?<\/h3>\n<p style=\"margin:0;\"><strong>Gamascab Lotion<\/strong> je <strong>lindane (gamma benzene hexachloride) 1% lotion<\/strong> in a 100 ml bottle \u2014 a <strong>second-line scabicide and pediculicide<\/strong> reserved for cases where permethrin and ivermectin have failed or are unavailable. Apply head-to-toe (neck-down), leave on <strong>6\u20138 hours only<\/strong> (NOT overnight), then wash off thoroughly. Lindane was withdrawn from the US market in 2009, the EU in 2008, and Canada in 2004 over neurotoxicity (seizures) and environmental persistence. Prefer <a href=\"https:\/\/medsbase.com\/cs\/permiforce-cream\/\">Permiforce Cream (permethrin 5%)<\/a> nebo <a href=\"https:\/\/medsbase.com\/cs\/iverjohn\/\">Iverjohn (oral ivermectin)<\/a> nejprve.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border-left:4px solid #2c7cb0;padding:14px 18px;margin:18px 0;border-radius:6px;font-size:0.95em;\">\n<strong>\ud83c\udfed V\u00fdrobce certifikovan\u00fd WHO-GMP<\/strong> \u00b7 <strong>\ud83d\udce6 Diskr\u00e9tn\u00ed balen\u00ed<\/strong> (oby\u010dejn\u00e1 ob\u00e1lka) \u00b7 <strong>\ud83c\udf0d Doprava do cel\u00e9ho sv\u011bta<\/strong> s <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance<\/strong><\/a> \u00b7 <strong>\u2b50 1 400+ z\u00e1kazn\u00edk\u016f<\/strong> \u2014 <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">\u010d\u00edst recenze<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:6px;\">\n<strong>\u26a0\ufe0f Restricted second-line therapy.<\/strong> Lindane (gamma-BHC \/ hexachlorocyclohexane) was withdrawn or restricted in the US, EU, Canada, Japan, and most of Latin America between 2004 and 2009 over neurotoxicity (seizures, especially after over-application, on broken skin, or in young children) and environmental persistence (Stockholm Convention POP listing). It remains available in some markets for use where modern alternatives have failed. Do not use as first-line. Maximum contact time <strong>6\u20138 hours<\/strong>, never overnight, never repeat sooner than 7 days, never use on broken skin, and never use in children under 6 years or during pregnancy.\n<\/div>\n<h3 class=\"wp-block-heading\">Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Choosing Gamascab Lotion from MedsBase gives you:<\/p>\n<ul>\n<li><strong>WHO-GMP certifikov\u00e1no<\/strong> \u2014 poch\u00e1z\u00ed z kontrolovan\u00fdch v\u00fdrobn\u00edch za\u0159\u00edzen\u00ed<\/li>\n<li><strong>Diskr\u00e9tn\u00ed balen\u00ed<\/strong> \u2014 oby\u010dejn\u00e1 ob\u00e1lka, bez viditeln\u00e9ho n\u00e1zvu l\u00e9ku nebo zna\u010dky l\u00e9k\u00e1rny<\/li>\n<li><strong>Dod\u00e1n\u00ed po cel\u00e9m sv\u011bt\u011b<\/strong> s <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\">Reshipment Assurance<\/a> \u2014 ka\u017ed\u00e1 objedn\u00e1vka je kryta<\/li>\n<li><strong>Ov\u011b\u0159en\u00e9 recenze z\u00e1kazn\u00edk\u016f<\/strong> \u2014 <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">1 400+ recenz\u00ed<\/a> nap\u0159\u00ed\u010d katalogem<\/li>\n<li><strong>V\u00edce platebn\u00edch mo\u017enost\u00ed<\/strong> \u2014 v\u010detn\u011b 10% slevy p\u0159i platb\u011b kryptom\u011bnou<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">What is Gamascab Lotion?<\/h2>\n<p>Gamascab Lotion is lindane (gamma benzene hexachloride) 1% lotion supplied in a 100 ml bottle. Gamascab Lotion is supplied by a WHO-GMP-certified manufacturer. Lindane is an organochlorine compound that has been used as a scabicide and pediculicide since the 1950s. Modern guidelines reserve it for the narrow situations where first-line agents (permethrin and ivermectin) have failed or are unavailable, because the safety margin is much narrower than for permethrin.<\/p>\n<h2 class=\"wp-block-heading\">How does lindane work?<\/h2>\n<p>Lindane is absorbed through the parasite&#8217;s cuticle and binds to GABA-A and glycine receptors in arthropod nervous tissue. The result is hyperexcitability, convulsions, and death of the mite or louse. Unfortunately the same receptor targets exist in mammals, which is why systemic absorption from human skin (~10 % of applied dose, more in young children and broken skin) can produce neurotoxic side effects \u2014 paraesthesia, headache, dizziness, and at toxic levels, seizures.<\/p>\n<h2 class=\"wp-block-heading\">Indications (second-line only)<\/h2>\n<ul>\n<li><strong>Svrab<\/strong> \u2014 when permethrin 5% (<a href=\"https:\/\/medsbase.com\/cs\/permiforce-cream\/\">Permiforce Cream<\/a>) and oral ivermectin (<a href=\"https:\/\/medsbase.com\/cs\/iverjohn\/\">Iverjohn<\/a> \/ <a href=\"https:\/\/medsbase.com\/cs\/verpin\/\">Verpin<\/a>) have failed or are contraindicated<\/li>\n<li><strong>V\u0161i hlavov\u00e9<\/strong> resistant to permethrin and where ivermectin lotion (<a href=\"https:\/\/medsbase.com\/cs\/ivrea-shampoo\/\">Ivrea Shampoo<\/a>) is not an option<\/li>\n<li><strong>Pubic lice<\/strong> in adults where modern alternatives are not available<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">How to apply Gamascab Lotion<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;\">Krok<\/th>\n<th style=\"padding:8px;text-align:left;\">Co d\u011blat<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:8px;border-bottom:1px solid #eee;\">1. Bath \/ shower<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #eee;\">Have a cool or lukewarm bath; <strong>dry the skin completely<\/strong>. Do not apply to hot, damp, or freshly bathed skin \u2014 this raises absorption sharply.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border-bottom:1px solid #eee;background:#f9f9f9;\">2. Apply thin layer<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #eee;background:#f9f9f9;\">Naneste <strong>thin<\/strong> layer to the whole body neck-down (avoid face). For scabies, work into all skin folds \u2014 between fingers, under nails, in armpits, around waist, genitals, behind knees. Use no more than ~30 mL for an average adult body.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border-bottom:1px solid #eee;\">3. Leave 6\u20138 hours<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #eee;\"><strong>Maximum 6\u20138 hours. Do NOT leave on overnight.<\/strong> Do not exceed this window \u2014 toxic absorption begins to climb steeply.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border-bottom:1px solid #eee;background:#f9f9f9;\">4. Wash off thoroughly<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #eee;background:#f9f9f9;\">Wash off completely with cool \/ lukewarm water and soap. Change into clean clothes. Wash bedding and worn clothes at \u2265 60 \u00b0C.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;\">5. Repeat ONLY if needed at day 7<\/td>\n<td style=\"padding:8px;\">A single application is usually sufficient. Repeat once at day 7 only if active disease persists. <strong>Never apply more than two courses<\/strong>.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 class=\"wp-block-heading\">Side effects and toxicity<\/h2>\n<p>Local reactions are common:<\/p>\n<ul>\n<li>Burning, stinging, redness, dryness, dermatitis<\/li>\n<li>Eczematous flare<\/li>\n<li>Headache, dizziness, paraesthesia (numbness\/tingling)<\/li>\n<\/ul>\n<p><strong>Serious \/ systemic \u2014 stop use and seek urgent medical help:<\/strong><\/p>\n<ul>\n<li>Seizures (rare; risk much higher with overuse, broken skin, or in young children)<\/li>\n<li>Severe headache, confusion, or muscle twitching<\/li>\n<li>Severe rash, blistering, or extensive irritation<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Contraindications and absolute avoid<\/h2>\n<ul>\n<li><strong>Children under 6 years<\/strong> \u2014 much greater absorption per kg; FDA black-box concerns<\/li>\n<li><strong>T\u011bhotenstv\u00ed a kojen\u00ed<\/strong> \u2014 lipid-soluble; crosses placenta and into breast milk<\/li>\n<li><strong>Broken, eczematous, or psoriatic skin<\/strong> \u2014 absorption is dramatically higher<\/li>\n<li><strong>Premature infants<\/strong>, low birth weight, malnourished children<\/li>\n<li><strong>Patients with seizure disorders<\/strong> or on lower-seizure-threshold drugs (theophylline, tricyclic antidepressants, bupropion, clozapine)<\/li>\n<li><strong>Porucha funkce jater<\/strong><\/li>\n<li><strong>Concurrent oils \/ moisturisers<\/strong> on the skin \u2014 they enhance absorption; remove before applying<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Interakce l\u00e9k\u016f<\/h2>\n<p>Avoid simultaneous topical or systemic drugs that lower seizure threshold. Lindane is metabolised hepatically and absorbed enough to interact with hepatic enzyme inducers and inhibitors when used over large surface areas or with extended contact.<\/p>\n<h2 class=\"wp-block-heading\">Skladov\u00e1n\u00ed<\/h2>\n<p>Store below 25 \u00b0C, away from heat and direct sunlight, in the original tightly capped bottle. Keep out of reach of children \u2014 paediatric ingestion is a medical emergency.<\/p>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3 class=\"wp-block-heading\">Why is lindane still available if it was withdrawn?<\/h3>\n<p>Lindane was withdrawn or restricted in the US (FDA 2009 second-line restriction), the EU (2008), Canada (2004), and is listed under the Stockholm Convention as a persistent organic pollutant. It remains available in some markets for narrow second-line use where first-line agents (permethrin \/ ivermectin) cannot be used. Gamascab Lotion is supplied for those situations under medical guidance.<\/p>\n<h3 class=\"wp-block-heading\">Why only 6\u20138 hours of contact?<\/h3>\n<p>Beyond 8 hours, the percentage of the applied dose absorbed through skin rises sharply \u2014 and so does the risk of CNS toxicity (paraesthesia, headache, in extreme cases seizure). Permethrin can be left on overnight because mammalian sodium channels recover quickly; lindane cannot.<\/p>\n<h3 class=\"wp-block-heading\">Can I use lindane if I&#8217;m pregnant?<\/h3>\n<p>No. Lindane crosses the placenta and is excreted in breast milk. Permethrin 5% (<a href=\"https:\/\/medsbase.com\/cs\/permiforce-cream\/\">Permiforce Cream<\/a>) is the safe choice during pregnancy.<\/p>\n<h3 class=\"wp-block-heading\">Is it safe in children?<\/h3>\n<p>Avoid in children under 6 years \u2014 they have a higher surface-area-to-weight ratio and absorb proportionally more. In children 6+, use only a single application under medical guidance and only if first-line therapies have failed.<\/p>\n<h3 class=\"wp-block-heading\">What if lindane gets in my eyes or mouth?<\/h3>\n<p>Rinse eyes with copious water for 15 minutes and seek medical advice. If swallowed, do not induce vomiting; contact a poison control centre immediately. Lindane is more toxic by ingestion than by skin absorption.<\/p>\n<h3 class=\"wp-block-heading\">How is Gamascab Lotion different from permethrin?<\/h3>\n<p>Different mechanism (GABA receptor blockade vs sodium-channel modulation), different safety margin (much narrower for lindane), and different first-line status (permethrin is recommended; lindane is reserved second-line). Choose lindane only if permethrin and ivermectin have both failed or are contraindicated.<\/p>\n<h3 class=\"wp-block-heading\">Can I use lindane on cracked or eczematous skin?<\/h3>\n<p>No \u2014 broken skin can absorb 5\u201310\u00d7 more drug. Treat the dermatitis first, or use permethrin \/ oral ivermectin instead.<\/p>\n<h3 class=\"wp-block-heading\">Will my itch go away after treatment?<\/h3>\n<p>Itch from scabies persists for 2\u20134 weeks after a successful course because the immune response continues against retained mite antigens. This is not treatment failure. New burrows or new lesions after 14 days does suggest failure \u2014 switch to permethrin + oral ivermectin combination.<\/p>\n<h3 class=\"wp-block-heading\">Do I need to treat household members?<\/h3>\n<p>Yes for scabies \u2014 close contacts may be in the asymptomatic 4\u20136 week incubation phase. For lindane specifically, treat them with permethrin (preferred) rather than another lindane course, to minimise repeat exposure to a restricted compound.<\/p>\n<h3 class=\"wp-block-heading\">Can I shower the next day?<\/h3>\n<p>Yes \u2014 once Gamascab Lotion is washed off after the 6\u20138 hour contact period, normal washing resumes. Do not re-apply for at least 7 days, and only if active infestation persists.<\/p>\n<h2 class=\"wp-block-heading\">Dal\u0161\u00ed l\u00e9\u010dba v\u0161\u00ed a svrabu<\/h2>\n<p class=\"medsbase-link-boost-2026-05-11\" data-marker=\"mb-link-boost-ivrea-shampoo\">Kde <a href=\"https:\/\/medsbase.com\/cs\/gamascab-lotion\/\">Gamascab Lotion (lindane 1%)<\/a> is contraindicated \u2014 in infants, pregnant patients, or those with compromised skin \u2014 <a href=\"https:\/\/medsbase.com\/cs\/ivrea-shampoo\/\">Ivrea Shampoo (ivermectin 1% \u0161ampon)<\/a> offers a mechanistically distinct, single-application alternative with a more favourable safety profile for pediculosis capitis.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/permiforce-cream\/\"><strong>Permiforce Cream<\/strong><\/a> \u2014 permethrin 5% cream \u2014 first-line scabies<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/perlice-cream\/\"><strong>Perlice Cream<\/strong><\/a> \u2014 lotion s permethrinem 1 % \u2014 prvn\u00ed volba l\u00e9\u010dby v\u0161\u00ed hlavov\u00e9<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/iverjohn\/\"><strong>Iverjohn<\/strong><\/a> \u2014 oral ivermectin 3 \/ 6 \/ 12 mg \u2014 first-line oral antiparasitic<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/verpin\/\"><strong>Verpin<\/strong><\/a> \u2014 ivermectin 6 mg tablets \u2014 alternative oral<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/ivrea-shampoo\/\"><strong>Ivrea Shampoo<\/strong><\/a> \u2014 topick\u00fd ivermektin 1 % \u2014 pro v\u0161i rezistentn\u00ed na permethrin<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">L\u00e9ka\u0159sk\u00e9 upozorn\u011bn\u00ed<\/h2>\n<p>Tato str\u00e1nka slou\u017e\u00ed pouze pro vzd\u011bl\u00e1vac\u00ed \u00fa\u010dely a nenahrazuje l\u00e9ka\u0159skou p\u00e9\u010di. Rezistentn\u00ed nebo atypick\u00e9 infekce, p\u0159etrv\u00e1vaj\u00edc\u00ed sv\u011bd\u011bn\u00ed navzdory spr\u00e1vn\u00e9 aplikaci, naka\u017een\u00e9 d\u011bti mlad\u0161\u00ed 2 let, imunokompromitovan\u00ed pacienti (riziko krust\u00f3zn\u00edho\/norsk\u00e9ho svrabu) a p\u0159\u00edpady v t\u011bhotenstv\u00ed \/ b\u011bhem kojen\u00ed vy\u017eaduj\u00ed klinick\u00e9 vy\u0161et\u0159en\u00ed. Rozs\u00e1hl\u00e1 ko\u017en\u00ed infekce, hore\u010dka nebo syst\u00e9mov\u00e9 p\u0159\u00edznaky po l\u00e9\u010db\u011b vy\u017eaduj\u00ed neodkladn\u00e9 l\u00e9ka\u0159sk\u00e9 vy\u0161et\u0159en\u00ed. V\u017edy konzultujte l\u00e9\u010dbu v t\u011bhotenstv\u00ed nebo b\u011bhem kojen\u00ed s l\u00e9ka\u0159em.<\/p>","protected":false},"excerpt":{"rendered":"<p>\u2705 Scabies treatment<br \/>\n\u2705 Kills mites<br \/>\n\u2705 Zm\u00edr\u0148uje sv\u011bd\u011bn\u00ed<br \/>\n\u2705 Easy application<br \/>\n\u2705 Rapid action<\/p>\n<p>Gamascab Lotion contains Lindane.<\/p>","protected":false},"featured_media":58110,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3342,3579],"product_tag":[4423,4424],"class_list":{"0":"post-58109","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-general-health","8":"product_cat-lice-scabies-treatment","9":"product_tag-gamascab-lotion","10":"product_tag-lindane","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/58109","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=58109"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/58110"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=58109"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=58109"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=58109"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=58109"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}