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Trajenta Duo<\/strong> je tableta s fixn\u00ed kombinac\u00ed linagliptin (2.5 mg)<\/strong> a metforminu (500 mg nebo 1000 mg)<\/strong> po dobu diabetu 2. typu<\/strong>. It pairs complementary mechanisms: metformin reduces hepatic glucose production and improves insulin sensitivity, while linagliptin (a DPP-4 inhibitor) raises incretin hormones to stimulate glucose-dependent insulin release and suppress glucagon. Expected HbA1c reduction: 1,5\u20132,0 procentn\u00edch bod\u016f<\/strong>. Neovliv\u0148uje hmotnost<\/strong> and very low hypoglycaemia risk as a combination. Usual dose: one tablet twice daily with meals. Main side effects are metformin GI upset in the first 1–2 weeks. The linagliptin component needs no renal dose adjustment; the metformin component follows standard rules — avoid if eGFR < 30. Avoid in type 1 diabetes, DKA, eGFR < 30, and severe hepatic impairment.<\/p>\n<\/div>\n \ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n Trajenta Duo is a fixed-dose combination oral antidiabetic tablet containing linagliptin (2.5 mg)<\/strong> a metformin hydrochlorid (500 mg nebo 1000 mg)<\/strong>, manufactured by Boehringer Ingelheim. Available in packs of 30, 60, 90 or 180 tablets. It is used when monotherapy with either component is not enough, or as initial combination therapy when HbA1c is substantially above target.<\/p>\n Trajenta Duo combines two complementary mechanisms that do not overlap:<\/p>\n Proto\u017ee \u017e\u00e1dn\u00e1 ze slo\u017eek nestimuluje uvol\u0148ov\u00e1n\u00ed inzulinu nez\u00e1visle na hladin\u011b gluk\u00f3zy v krvi, kombinace m\u00e1 velmi n\u00edzk\u00e9 riziko hypoglyk\u00e9mie. Typick\u00e9 sn\u00ed\u017een\u00ed HbA1c: 1,5\u20132,0 procentn\u00edch bod\u016f<\/strong>. Vliv na hmotnost: neutr\u00e1ln\u00ed nebo m\u00edrn\u011b sni\u017euj\u00edc\u00ed hmotnost (d\u00edky metforminu).<\/p>\n Obvykl\u00e1 d\u00e1vka:<\/strong> jedna tableta dvakr\u00e1t denn\u011b, s sn\u00eddan\u00ed a ve\u010de\u0159\u00ed. D\u00e1vka je individualizov\u00e1na na z\u00e1klad\u011b p\u0159edchoz\u00ed terapie, c\u00edlov\u00e9 hodnoty HbA1c a ren\u00e1ln\u00ed funkce.<\/p>\n Ne\u017e\u00e1douc\u00ed \u00fa\u010dinky metforminu (obvykle prvn\u00ed 1\u20132 t\u00fddny):<\/strong><\/p>\n Ne\u017e\u00e1douc\u00ed \u00fa\u010dinky DPP-4 inhibitoru:<\/strong><\/p>\n Vz\u00e1cn\u00e9, ale z\u00e1va\u017en\u00e9:<\/strong><\/p>\n Store Trajenta Duo below 30°C in a dry place, in the original blister pack. Keep out of reach of children.<\/p>\n Klinicky ano \u2014 stejn\u00e9 molekuly ve stejn\u00fdch d\u00e1vk\u00e1ch. Fixn\u00ed kombinace zlep\u0161uje adherenci, sni\u017euje po\u010det tablet a obvykle stoj\u00ed m\u00e9n\u011b ne\u017e dv\u011b slo\u017eky zakoupen\u00e9 samostatn\u011b. Nev\u00fdhodou je men\u0161\u00ed flexibilita d\u00e1vkov\u00e1n\u00ed.<\/p>\n On its own, very rarely. Neither DPP-4 inhibitors nor metformin stimulates insulin release independent of glucose. Hypoglycaemia becomes a concern only when Trajenta Duo is combined with a sulfonylurea, meglitinide, or insulin.<\/p>\n Ne. Tato kombinace je neutr\u00e1ln\u00ed v\u016f\u010di hmotnosti nebo m\u00edrn\u011b sni\u017euje hmotnost, co\u017e je hlavn\u00ed d\u016fvod, pro\u010d je up\u0159ednost\u0148ov\u00e1na p\u0159ed kombinacemi zalo\u017een\u00fdmi na sulfonylure\u00e1ch u pacient\u016f s nadv\u00e1hou.<\/p>\n Hladina gluk\u00f3zy nala\u010dno za\u010dne klesat do t\u00fddne. Maxim\u00e1ln\u00ed \u00fa\u010dinek na HbA1c je po 12 t\u00fddnech. Pokud HbA1c neklesne alespo\u0148 o 0,5 % po 3 m\u011bs\u00edc\u00edch u c\u00edlov\u00e9 d\u00e1vky, m\u016f\u017ee b\u00fdt nutn\u00e1 dal\u0161\u00ed terapie.<\/p>\n St\u0159\u00eddm\u00e1 konzumace alkoholu s j\u00eddlem je obvykle bezpe\u010dn\u00e1. Vyhn\u011bte se n\u00e1razov\u00e9mu pit\u00ed \u2014 zvy\u0161uje riziko lakt\u00e1tov\u00e9 acid\u00f3zy (metformin) a m\u016f\u017ee naru\u0161it funkci jater.<\/p>\n You can order Trajenta Duo (Linagliptin 2.5 mg + Metformin 500\/1000 mg (twice daily)) from MedsBase in packs of 30, 60, 90 or 180 tablets. We ship worldwide, with discreet packaging and genuine WHO-GMP certified manufacturer stock.<\/p>\n Patients discontinuing the linagliptin component of Trajenta Duo<\/a> while continuing metformin may transition directly to Glycomet SR (metformin hydrochloride 500\u20131000 mg SR)<\/a>, available in the same 500 mg and 1000 mg SR strengths as the original combination tablet.<\/p>\n <\/p>\n Dal\u0161\u00ed produkty v Chronick\u00e1 onemocn\u011bn\u00ed<\/strong> kter\u00e9 z\u00e1kazn\u00edci tak\u00e9 prohl\u00ed\u017eej\u00ed:<\/p>\n \u2705 Dual-action control Trajenta Duo contains Linagliptin & Metformin.<\/p>","protected":false},"featured_media":58206,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3230,3231],"product_tag":[3278,3255,4443],"class_list":{"0":"post-58205","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-diabetes","9":"product_cat-diabetes-medication","10":"product_tag-linagliptin","11":"product_tag-metformin","12":"product_tag-trajenta-duo","14":"first","15":"instock","16":"shipping-taxable","17":"purchasable","18":"product-type-variable","19":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/58205","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=58205"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/58206"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=58205"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=58205"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=58205"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=58205"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n
What Is Trajenta Duo?<\/h2>\n
How Does Trajenta Duo Work?<\/h2>\n
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D\u00e1vkov\u00e1n\u00ed a pod\u00e1n\u00ed<\/h2>\n
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Vedlej\u0161\u00ed \u00fa\u010dinky<\/h2>\n
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Interakce s l\u00e9\u010divy<\/h2>\n
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Who Should Not Take Trajenta Duo?<\/h2>\n
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Skladov\u00e1n\u00ed<\/h2>\n
\u010casto kladen\u00e9 dotazy<\/h2>\n
Is Trajenta Duo the same as taking Trajenta and metformin separately?<\/h3>\n
Will Trajenta Duo cause hypoglycaemia?<\/h3>\n
Will I gain weight on Trajenta Duo?<\/h3>\n
How long before Trajenta Duo starts working?<\/h3>\n
Can I drink alcohol while taking Trajenta Duo?<\/h3>\n
Where can I buy Trajenta Duo online?<\/h3>\n
Souvisej\u00edc\u00ed l\u00e9ky na diabetes<\/h2>\n
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Souvisej\u00edc\u00ed alternativy<\/h3>\n
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\n\u2705 Regulates blood sugar
\n\u2705 Combines two medications
\n\u2705 Zlep\u0161uje citlivost na inzul\u00edn
\n\u2705 Manages type 2 diabetes<\/p>\n