{"id":58511,"date":"2024-02-27T18:40:43","date_gmt":"2024-02-27T18:40:43","guid":{"rendered":"https:\/\/medsname.com\/polybion-ampoule\/"},"modified":"2026-04-30T10:24:12","modified_gmt":"2026-04-30T10:24:12","slug":"polybion-ampoule","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/polybion-ampoule\/","title":{"rendered":"Polybion Ampule"},"content":{"rendered":"<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<h3 style=\"margin-top:0;\">Rychl\u00e1 odpov\u011b\u010f<\/h3>\n<p><strong>Polybion Ampoule (B-complex with B12 multi-B parenteral ampoule (Merck))<\/strong> is a parenteral B-complex preparation (B1, B2, B3, B5, B6, B12) used for rapid replacement when oral absorption is impaired or in alcoholic patients with multi-B deficiency.<\/p>\n<ul style=\"margin-bottom:0;\">\n<li>B1 (thiamine), B2 (riboflavin), B3 (niacinamide), B5 (dexpanthenol), B6 (pyridoxine), B12 (cyanocobalamin)<\/li>\n<li>IM or slow IV (per label), single ampoule dose<\/li>\n<li>Indications: malabsorption, alcohol use disorder, severe nutritional deficiency, post-bariatric<\/li>\n<li>WHO-GMP certified manufacturer (Merck)<\/li>\n<\/ul>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f6f8;border:1px solid #e0e4e7;padding:12px 16px;margin:18px 0;border-radius:4px;font-size:14px;color:#444;\">\n<strong>v\u00fdrobce certifikovan\u00e9ho WHO-GMP<\/strong> \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\" style=\"color:#2c7cb0;\">1 400+ ov\u011b\u0159en\u00fdch recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<p style=\"font-size:13px;color:#666;margin:4px 0 18px;\">Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00edm <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\" style=\"color:#2c7cb0;\">Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/a>.<\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Polybion Ampoule is sourced from a WHO-GMP certified manufacturer. Every order ships in discreet, unbranded packaging worldwide and is covered by our Reshipment Assurance Policy. Pay securely with credit card, SEPA bank transfer, or cryptocurrency. See our <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">1 400+ ov\u011b\u0159en\u00fdch recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>.<\/p>\n<h2>What is Polybion Ampoule?<\/h2>\n<p>Polybion is a multi-B-complex injection combining the major water-soluble B vitamins in a single ampoule for IM (or slow IV) administration. The combination addresses the typical pattern of multi-B deficiency seen in alcohol use disorder, severe malnutrition, post-bariatric malabsorption, and prolonged TPN without adequate B-vitamin coverage.<\/p>\n<h2>Indikace<\/h2>\n<ul>\n<li><strong>Severe nutritional deficiency<\/strong> in malnutrition or eating disorders<\/li>\n<li><strong>Porucha u\u017e\u00edv\u00e1n\u00ed alkoholu<\/strong> &mdash; multi-B deficiency (especially thiamine, B12, folate) is the rule rather than exception<\/li>\n<li><strong>Post-bariatric malabsorption<\/strong> &mdash; particularly after Roux-en-Y or BPD-DS<\/li>\n<li><strong>Prolonged severe diarrhoea, fistula losses<\/strong><\/li>\n<li><strong>Hyperemesis gravidarum<\/strong> &mdash; thiamine + B-complex parenteral cover<\/li>\n<li><strong>Refeeding syndrome prophylaxis<\/strong> &mdash; thiamine load before refeeding (specialist)<\/li>\n<li><strong>Adjunct in peripheral neuropathy<\/strong> of mixed nutritional aetiology<\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<strong>Wernicke&#8217;s encephalopathy needs HIGH-DOSE thiamine, not B-complex<\/strong><\/p>\n<p style=\"margin-bottom:0;\">In suspected Wernicke&#8217;s encephalopathy (confusion, ataxia, ophthalmoplegia &mdash; classically in alcohol use disorder, hyperemesis, refeeding) standard B-complex preparations like Polybion deliver INSUFFICIENT thiamine for treatment. Specialist guidance is high-dose IV thiamine 500 mg three times daily for 2&ndash;3 days, then 250 mg daily. Polybion is appropriate for prevention and routine replacement; Wernicke&#8217;s treatment needs dedicated high-dose thiamine.<\/p>\n<\/div>\n<h2>D\u00e1vka<\/h2>\n<p>Typical use: one ampoule IM or slow IV daily for 5&ndash;7 days, then once weekly until oral intake is restored, then transition to oral B-complex (Beplex Forte, Becozinc) for maintenance. In hospital settings the dose and route are individualised to the indication.<\/p>\n<h2>Vedlej\u0161\u00ed \u00fa\u010dinky<\/h2>\n<ul>\n<li><strong>Injection site reaction<\/strong> &mdash; common, usually mild<\/li>\n<li><strong>Anaphylaxis<\/strong> &mdash; rare but reported with parenteral thiamine; resuscitation should be available for first IV doses in high-risk patients<\/li>\n<li><strong>Pyridoxine neuropathy<\/strong> &mdash; only at sustained extreme doses (B6 &gt;500 mg\/day for weeks)<\/li>\n<li><strong>Niacin flushing<\/strong> &mdash; transient<\/li>\n<li><strong>Yellow discoloration of urine<\/strong> from riboflavin &mdash; harmless<\/li>\n<\/ul>\n<h2>Interakce l\u00e9k\u016f<\/h2>\n<ul>\n<li><strong>Levodopa<\/strong> &mdash; B6 (pyridoxine) reduces effect of unprotected levodopa (relevant if levodopa is given without a peripheral decarboxylase inhibitor, which is rare in modern formulations)<\/li>\n<li><strong>Fenytoin<\/strong> &mdash; pyridoxine may slightly reduce phenytoin levels<\/li>\n<li><strong>Kli\u010dkov\u00e1 diuretika<\/strong> &mdash; can deplete thiamine; high-dose loop users (heart failure) may benefit from B-complex supplementation<\/li>\n<\/ul>\n<h2>Kontraindikace<\/h2>\n<ul>\n<li>P\u0159ecitliv\u011blost na kteroukoli slo\u017eku<\/li>\n<li>Active peptic ulcer (relative; high-dose niacinamide can aggravate)<\/li>\n<\/ul>\n<h2>Skladov\u00e1n\u00ed<\/h2>\n<p>Skladujte p\u0159i teplot\u011b do 25\u00b0C, chra\u0148te p\u0159ed sv\u011btlem. Ampule pou\u017eijte ihned po otev\u0159en\u00ed.<\/p>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3>When is parenteral B-complex needed instead of oral?<\/h3>\n<p>When absorption is impaired (malabsorption, post-bariatric, severe diarrhoea), when adherence is unreliable, when rapid replacement is needed, or when the patient cannot tolerate oral intake (severe vomiting, post-op fasting). Otherwise oral B-complex (Beplex Forte, Becozinc) is preferred &mdash; cheaper and effective.<\/p>\n<h3>Will it help with fatigue?<\/h3>\n<p>Only if fatigue is due to documented B-vitamin deficiency. Most fatigue in well-fed adults is not B-vitamin deficiency; check thyroid, ferritin, vitamin D, B12, folate, glucose, and depression first. Megadose B-complex without deficiency does not increase energy.<\/p>\n<h3>Is the injection painful?<\/h3>\n<p>Some discomfort at the site is common. Slow IV injection (where label permits) reduces stinging.<\/p>\n<h3>Mohu jej u\u017e\u00edvat dlouhodob\u011b?<\/h3>\n<p>Long-term parenteral B-complex is unusual. If maintenance is needed, transition to oral (Beplex Forte, Becozinc) or specific replacement (B12 IM monthly for pernicious anaemia, oral folate, oral thiamine). Re-injecting B-complex monthly without indication is not evidence-based.<\/p>\n<h3>Does it help peripheral neuropathy?<\/h3>\n<p>In neuropathy with documented B-vitamin deficiency (alcoholic, diabetic with B12 deficiency, post-bariatric, malabsorption), replacement helps. In neuropathy without deficiency the benefit is small to none.<\/p>\n<h3>Je bezpe\u010dn\u00fd v t\u011bhotenstv\u00ed?<\/h3>\n<p>Used in hyperemesis gravidarum with thiamine cover for Wernicke prophylaxis. Megadose B6 (pyridoxine) above 500 mg\/day for weeks risks fetal sensory neuropathy; standard parenteral B-complex doses are well below this.<\/p>\n<h3>What about thiamine alone in alcohol use disorder?<\/h3>\n<p>High-risk alcohol-use-disorder patients (especially those representing for detox or with refeeding risk) should receive parenteral thiamine 100&ndash;300 mg before any glucose-containing fluids &mdash; glucose without thiamine can precipitate Wernicke&#8217;s in deficient patients. Polybion contains thiamine but the concentration may be insufficient for high-risk treatment doses.<\/p>\n<h3>Jak rychle \u00fa\u010dinkuje?<\/h3>\n<p>Onset depends on indication. For nutritional deficiency, biochemistry begins improving within days, clinical symptoms over weeks. For acute Wernicke&#8217;s, dedicated high-dose thiamine is needed (not standard B-complex).<\/p>\n<h3>Polybion vs Walcobal?<\/h3>\n<p>Polybion is multi-B (1, 2, 3, 5, 6, 12). Walcobal is methylcobalamin only at higher dose (2500 mcg vs the smaller B12 amount in Polybion). Use Polybion for multi-B deficiency, Walcobal for isolated B12 deficiency or B12-specific neuropathy.<\/p>\n<h3>Can my GP give me Polybion?<\/h3>\n<p>Yes &mdash; IM injection is within standard primary care scope. Always confirm the indication and ensure resuscitation is available for first parenteral B-complex dose in patients with allergy history.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h2>Ostatn\u00ed vitam\u00edny a miner\u00e1ly<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/vitamin-b12-1500-mcg-tablets-nerve-health-energy\/\">Vitamin B12 1500 mcg<\/a> \u2014 vysokod\u00e1vkovan\u00fd peror\u00e1ln\u00ed kyanokobalamin<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/walcobal-injection\/\">Walcobal Injekce<\/a> \u2014 methylkobalamin IM<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/polybion-ampoule\/\">Polybion Ampule<\/a> \u2014 parenter\u00e1ln\u00ed B-komplex<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/beplex-forte\/\">Beplex Forte<\/a> \u2014 peror\u00e1ln\u00ed B-komplex<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/becozinc\/\">Becozinc<\/a> \u2014 B-komplex se zinkem<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/thiamine-hcl-100\/\">Thiamin HCL 100<\/a> \u2014 thiamin 100 mg pro alkoholovou neuropatii<\/li>\n<\/ul>\n<h2>L\u00e9ka\u0159sk\u00e9 upozorn\u011bn\u00ed<\/h2>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;color:#444;\">\nTato str\u00e1nka slou\u017e\u00ed pouze pro vzd\u011bl\u00e1vac\u00ed \u00fa\u010dely a nenahrazuje odbornou l\u00e9ka\u0159skou pomoc. Dopln\u011bn\u00ed vitam\u00edn\u016f a miner\u00e1l\u016f by m\u011blo b\u00fdt ide\u00e1ln\u011b vedeno laboratorn\u00edmi testy, pokud je podez\u0159en\u00ed na nedostatek. Megad\u00e1vky dopl\u0148k\u016f nejsou ne\u0161kodn\u00e9 \u2014 vitamin A je teratogenn\u00ed, vitamin E zvy\u0161uje riziko krv\u00e1cen\u00ed, beta-karoten zvy\u0161uje riziko rakoviny plic u ku\u0159\u00e1k\u016f a vysok\u00e9 d\u00e1vky v\u00e1pn\u00edku maj\u00ed kardiovaskul\u00e1rn\u00ed \u00fa\u010dinky. T\u011bhotn\u00e9 nebo koj\u00edc\u00ed pacientky by m\u011bly dodr\u017eovat doporu\u010den\u00ed pro prenat\u00e1ln\u00ed suplementaci. Pacienti u\u017e\u00edvaj\u00edc\u00ed warfarin mus\u00ed udr\u017eovat stabiln\u00ed p\u0159\u00edjem vitaminu K. Pacienti u\u017e\u00edvaj\u00edc\u00ed levothyroxin, fluorochinolony nebo tetracykliny mus\u00ed odd\u011blit p\u0159\u00edjem \u017eeleza a v\u00e1pn\u00edku o 4 hodiny. V\u017edy informujte sv\u00e9ho l\u00e9ka\u0159e a l\u00e9k\u00e1rn\u00edka o v\u0161ech dopl\u0148c\u00edch stravy.\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u2705 Vitamin B complex support<br \/>\n\u2705 Zvy\u0161uje energetickou hladinu<br \/>\n\u2705 Enhances nerve function<br \/>\n\u2705 Supports metabolism<br \/>\n\u2705 Promotes cell health<\/p>\n<p><strong>Polybion Ampule<\/strong> obsahuje <strong>Vitamin B Complex<\/strong> &amp; <strong>Vitamin B12<\/strong>.<\/p>","protected":false},"featured_media":58512,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[3141,3342,3863],"product_tag":[4505,4506,4507,3862],"class_list":{"0":"post-58511","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-general-health","8":"product_cat-vitamins-and-minerals","9":"product_tag-polybion","10":"product_tag-polybion-ampoule","11":"product_tag-vitamin-b-complex","12":"product_tag-vitamin-b12","14":"first","15":"instock","16":"shipping-taxable","17":"purchasable","18":"product-type-variable","19":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/58511","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=58511"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/58512"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=58511"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=58511"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=58511"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=58511"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}