{"id":58560,"date":"2024-02-27T18:43:48","date_gmt":"2024-02-27T18:43:48","guid":{"rendered":"https:\/\/medsname.com\/urifon\/"},"modified":"2026-04-30T10:16:50","modified_gmt":"2026-04-30T10:16:50","slug":"urifon","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/urifon\/","title":{"rendered":"Urifon"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:18px 0;border-radius:4px;\">\n<p style=\"margin:0 0 8px 0;\"><strong>\ud83d\udca1 Rychl\u00e1 odpov\u011b\u010f<\/strong><\/p>\n<p style=\"margin:0;\"><strong>Urifon<\/strong> je <strong>nitrofurantoin<\/strong>, a first-line oral antibiotic for uncomplicated <strong>infekc\u00edch mo\u010dov\u00fdch cest (IMC)<\/strong> \u2014 not for sexually transmitted infections. It concentrates in urine to kill <em>E. coli<\/em> and other common UTI pathogens. Typical dose: 100 mg twice daily for 5 days. Do not use for kidney infections (pyelonephritis) or prostate infections.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Co z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n<div style=\"background:#f4f8fb;border-left:4px solid #2c7cb0;padding:14px 20px;margin:16px 0;border-radius:4px;font-size:0.95em;\">\n<strong>\ud83d\udd12 Pro\u010d nakupovat na MedsBase:<\/strong> Ov\u011b\u0159en\u00e9 z\u00e1soby od skute\u010dn\u00e9ho v\u00fdrobce \u00b7 Diskr\u00e9tn\u00ed celosv\u011btov\u00e1 doprava \u00b7 Bezpe\u010dn\u00e9 platby (kreditn\u00ed karta, kryptom\u011bny) \u00b7 Hodnoceno 4,9\u2605 od 1 400+ z\u00e1kazn\u00edk\u016f\n<\/div>\n<h2><strong>What Is Urifon?<\/strong><\/h2>\n<p>Urifon is a branded generic of <strong>nitrofurantoin<\/strong>, a nitrofuran antibiotic developed in the 1950s that has re-emerged as <strong>first-line therapy for uncomplicated urinary tract infections<\/strong> (cystitis) thanks to its narrow spectrum, high urinary concentration, and low resistance rates. Available in strengths of <strong>100 mg<\/strong>.<\/p>\n<p><strong>Important note on category:<\/strong> nitrofurantoin treats bacterial UTIs \u2014 it is not used for sexually transmitted infections. Although UTIs and STIs can both cause dysuria (painful urination), the pathogens, treatments, and follow-up differ significantly.<\/p>\n<h2><strong>Klinick\u00e9 pou\u017eit\u00ed<\/strong><\/h2>\n<ul>\n<li><strong>Uncomplicated UTI (cystitis) in women:<\/strong> 100 mg twice daily for 5 days (modified-release) \u2014 first-line per IDSA, EAU, NICE.<\/li>\n<li><strong>UTI prophylaxis (long-term):<\/strong> 50\u2013100 mg once daily at bedtime for recurrent UTIs (short or long term).<\/li>\n<li><strong>Asymptomatick\u00e1 bakteriurie v t\u011bhotenstv\u00ed<\/strong> (first and second trimester): 100 mg twice daily for 5\u20137 days. <strong>Avoid at term (\u226536 weeks)<\/strong> \u2014 see below.<\/li>\n<li><strong>Not for:<\/strong> kidney infections (pyelonephritis) \u2014 nitrofurantoin does not achieve adequate tissue concentrations outside the urine. <strong>Not for<\/strong> prostate infections, bloodstream infections, or systemic sepsis.<\/li>\n<\/ul>\n<h2><strong>Jak u\u017e\u00edvat<\/strong><\/h2>\n<ol>\n<li>Take with food or milk \u2014 improves absorption and reduces stomach upset.<\/li>\n<li>Swallow capsules whole with a full glass of water. Stay well hydrated while on treatment.<\/li>\n<li>Complete the <strong>full course<\/strong> (5 days for acute UTI) even if symptoms resolve within 1\u20132 days. Stopping early promotes resistance and may allow the infection to return.<\/li>\n<li>Nitrofurantoin may turn urine dark yellow, brown, or rust-coloured \u2014 this is harmless.<\/li>\n<li>For recurrent UTIs, post-coital single-dose prophylaxis (one dose after sex) may be prescribed by a clinician.<\/li>\n<\/ol>\n<h2><strong>Critical Warnings<\/strong><\/h2>\n<ul>\n<li><strong>Renal function:<\/strong> not effective if creatinine clearance is &lt;30\u201345 mL\/min. At low GFR, urinary drug concentration is too low to work and systemic toxicity risk rises. Older patients especially need eGFR checked before use.<\/li>\n<li><strong>Pulmonary toxicity (rare but serious):<\/strong> acute (allergic pneumonitis) usually within weeks of starting. Chronic (pulmonary fibrosis) with long-term prophylactic use. Report shortness of breath, cough, or fever immediately.<\/li>\n<li><strong>Hepatotoxicity (rare):<\/strong> chronic use can cause liver injury. Monitor liver function on long-term prophylaxis.<\/li>\n<li><strong>Perifern\u00ed neuropatie:<\/strong> risk increases with renal impairment, diabetes, B-vitamin deficiency, and long treatment duration.<\/li>\n<li><strong>Pregnancy at term (\u226536 weeks)<\/strong> and in neonates &lt;1 month: risk of hemolytic anaemia in the newborn (G6PD deficiency). <strong>Vylou\u010dit kombinaci.<\/strong><\/li>\n<li><strong>G6PD deficiency:<\/strong> contraindicated \u2014 risk of acute haemolysis.<\/li>\n<\/ul>\n<h2><strong>Vedlej\u0161\u00ed \u00fa\u010dinky<\/strong><\/h2>\n<p><strong>\u010cast\u00e9 (\u22651 %):<\/strong> nausea, loss of appetite, headache. Taking with food usually helps.<\/p>\n<p><strong>M\u00e9n\u011b \u010dast\u00e9:<\/strong> diarrhoea, dizziness, rash, harmless urine discolouration.<\/p>\n<p><strong>Z\u00e1va\u017en\u00e9 (vz\u00e1cn\u00e9):<\/strong> acute pulmonary reaction, chronic pulmonary fibrosis, peripheral neuropathy, hepatotoxicity, haemolytic anaemia (G6PD), <em>Clostridioides difficile<\/em> kolitidu.<\/p>\n<h2><strong>Who Should Not Take Urifon<\/strong><\/h2>\n<ul>\n<li>eGFR \/ creatinine clearance &lt;30\u201345 mL\/min (drug ineffective + toxic)<\/li>\n<li>deficit G6PD<\/li>\n<li>Pregnancy at term (\u226536 weeks) or during labour<\/li>\n<li>Infants under 1 month<\/li>\n<li>Previous history of nitrofurantoin-induced pulmonary reaction or liver injury<\/li>\n<li>Zn\u00e1m\u00e1 p\u0159ecitliv\u011blost<\/li>\n<\/ul>\n<h2><strong>Interakce s l\u00e9\u010divy<\/strong><\/h2>\n<ul>\n<li><strong>Antacida<\/strong> (especially magnesium trisilicate): reduce absorption \u2014 separate doses.<\/li>\n<li><strong>Probenecid:<\/strong> reduces renal excretion of nitrofurantoin, raising systemic levels and reducing urinary levels (effectively making the drug less useful for UTI).<\/li>\n<li><strong>Fluoroquinolones:<\/strong> should not be combined \u2014 nitrofurantoin may antagonise fluoroquinolone activity.<\/li>\n<li>No significant interactions with hormonal contraceptives or most other commonly-used drugs.<\/li>\n<\/ul>\n<h2><strong>UTI vs STI \u2014 Know the Difference<\/strong><\/h2>\n<p>UTI and STI symptoms overlap (painful urination, frequency, urgency) but the pathogens and treatments are very different. Nitrofurantoin treats UTIs caused by <em>E. coli<\/em>, <em>Enterococcus<\/em>, <em>Staphylococcus saprophyticus<\/em>, a <em>Klebsiella<\/em>. Neplat\u00ed <strong>ne<\/strong> treat chlamydia, gonorrhea, mycoplasma, or trichomonas. If you have recent new sexual partner(s) or urethral discharge, test for STIs before assuming a UTI.<\/p>\n<h2><strong>Skladov\u00e1n\u00ed<\/strong><\/h2>\n<p>Store at room temperature (15\u201325 \u00b0C \/ 59\u201377 \u00b0F), away from moisture and light. Keep in original packaging. Keep out of reach of children.<\/p>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3 class=\"wp-block-heading\">Why is Urifon first-line for UTI?<\/h3>\n<p>Nitrofurantoin has a narrow spectrum (mostly UTI pathogens), concentrates in urine, and has stable resistance rates even after 60 years of use. It spares gut flora better than broad-spectrum alternatives like trimethoprim-sulfamethoxazole or fluoroquinolones.<\/p>\n<h3 class=\"wp-block-heading\">How fast does Urifon work?<\/h3>\n<p>Most patients feel improvement within 24\u201348 hours. Full 5-day course is still required \u2014 stopping early leaves residual bacteria that can re-establish infection.<\/p>\n<h3 class=\"wp-block-heading\">Can I use Urifon for a kidney infection?<\/h3>\n<p>No. Nitrofurantoin does not reach adequate tissue levels outside urine, so it cannot treat pyelonephritis or pyelitis. Fever, flank pain, or nausea with UTI symptoms need a different antibiotic.<\/p>\n<h3 class=\"wp-block-heading\">Why does my urine turn dark?<\/h3>\n<p>Nitrofurantoin colours urine dark yellow, brown, or rust \u2014 this is harmless and stops when treatment ends. Does not indicate bleeding or kidney damage.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Urifon while pregnant?<\/h3>\n<p>In the first and second trimesters, yes \u2014 widely used and considered safe. Avoid at term (\u226536 weeks) and during labour due to neonatal hemolytic anaemia risk.<\/p>\n<h3 class=\"wp-block-heading\">Can Urifon be used for STIs?<\/h3>\n<p>No. Nitrofurantoin does not cover chlamydia, gonorrhea, mycoplasma genitalium, or trichomonas. If your symptoms include urethral discharge, genital ulcers, or recent new sexual contact, request STI testing \u2014 treatment is different.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Urifon with birth control pills?<\/h3>\n<p>Yes \u2014 no significant interaction with hormonal contraceptives. Continue your usual pill\/patch\/ring as prescribed.<\/p>\n<h3 class=\"wp-block-heading\">What if UTIs keep coming back?<\/h3>\n<p>Recurrent UTIs (\u22652 in 6 months or \u22653 in 12 months) warrant investigation. Options include post-coital single-dose prophylaxis, nightly low-dose prophylaxis, vaginal oestrogen (post-menopause), and behavioural changes. Your clinician can tailor a plan.<\/p>\n<h3 class=\"wp-block-heading\">Souvisej\u00edc\u00ed produkty a pr\u016fvodci<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/urivron\/\">Urivron (Nitrofurantoin)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/uriheal\/\">Uriheal (Nitrofurantoin)<\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 20px;margin:16px 0;border-radius:4px;font-size:0.9em;\">\n<p style=\"margin:0;\"><strong>\u2695\ufe0f L\u00e9ka\u0159sk\u00e9 upozorn\u011bn\u00ed:<\/strong> Informace na t\u00e9to str\u00e1nce slou\u017e\u00ed pouze pro vzd\u011bl\u00e1vac\u00ed \u00fa\u010dely a nenahrazuj\u00ed l\u00e9ka\u0159skou pomoc. P\u0159ed zah\u00e1jen\u00edm, ukon\u010den\u00edm nebo zm\u011bnou jak\u00e9hokoli l\u00e9ku se v\u017edy pora\u010fte s kvalifikovan\u00fdm l\u00e9ka\u0159em. L\u00e9ky na p\u0159edpis by m\u011bly b\u00fdt u\u017e\u00edv\u00e1ny pouze pod l\u00e9ka\u0159sk\u00fdm dohledem.<\/p>\n<\/div>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Souvisej\u00edc\u00ed alternativy<\/h3>\n<p>Dal\u0161\u00ed produkty v <strong>Obecn\u00e9 zdrav\u00ed<\/strong> kter\u00e9 z\u00e1kazn\u00edci tak\u00e9 prohl\u00ed\u017eej\u00ed:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/gate-p-eye-drops\/\">Gate P o\u010dn\u00ed kapky<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/nepalact-eye-drops\/\">Nepalact o\u010dn\u00ed kapky<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/emeset\/\">Emeset<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/aceret\/\">Aceret<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/gr8-od\/\">GR8-OD<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Treats UTIs effectively<br \/>\n\u2705 Bojuje proti bakteri\u00e1ln\u00edm infekc\u00edm<br \/>\n\u2705 Alleviates urinary discomfort<br \/>\n\u2705 Prevents UTI recurrence<br \/>\n\u2705 Promotes rapid recovery<\/p>\n<p>Urifon contains Nitrofurantoin.<\/p>","protected":false},"featured_media":58561,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3484,3614,3141,3342],"product_tag":[4516,4518],"class_list":{"0":"post-58560","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-antibiotics","7":"product_cat-bladder-prostate","8":"product_cat-category-overview","9":"product_cat-general-health","10":"product_tag-nitrofurantoin","11":"product_tag-urifon","13":"first","14":"instock","15":"shipping-taxable","16":"purchasable","17":"product-type-variable","18":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/58560","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=58560"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/58561"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=58560"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=58560"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=58560"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=58560"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}