{"id":58712,"date":"2024-02-28T05:24:15","date_gmt":"2024-02-28T05:24:15","guid":{"rendered":"https:\/\/medsname.com\/neurobion-forte-rf-injection\/"},"modified":"2026-05-01T10:49:14","modified_gmt":"2026-05-01T10:49:14","slug":"neurobion-forte-rf-injection","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/neurobion-forte-rf-injection\/","title":{"rendered":"Neurobion Forte RF Injekce (Methylkobalamin + B6 + B3) \u2014 Oprava nerv\u016f"},"content":{"rendered":"
\n

Rychl\u00e1 odpov\u011b\u010f<\/h3>\n

Neurobion Forte RF injekce<\/strong> je 2 ml intramuskul\u00e1rn\u00ed ampule obsahuj\u00edc\u00ed methylkobalamin (vitamin B12), pyridoxine (vitamin B6) a nikotinamid (vitamin B3)<\/strong> \u2014 t\u0159i B-vitaminy kl\u00ed\u010dov\u00e9 pro funkci a regeneraci perifern\u00edch nerv\u016f. Pou\u017e\u00edv\u00e1 se p\u0159i diabetick\u00e9 neuropatii, alkoholov\u00e9 neuropatii, postherpetick\u00e9 neuralgii, ischiasu a klinick\u00e9m nedostatku B-vitamin\u016f. Injekce poskytuje vysok\u00e9 d\u00e1vky B-vitamin\u016f, kdy\u017e je peror\u00e1ln\u00ed suplementace p\u0159\u00edli\u0161 pomal\u00e1 nebo je absorpce naru\u0161ena (gastrektomie, bariatrick\u00e1 operace, onemocn\u011bn\u00ed ilea). Typick\u00e9 sch\u00e9ma: obden po dobu 2 t\u00fddn\u016f, pot\u00e9 t\u00fddenn\u00ed udr\u017eovac\u00ed d\u00e1vky.<\/p>\n<\/div>\n

\nCo z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n

\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n

Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n

Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n

Co je Neurobion Forte RF injekce?<\/h2>\n

Neurobion Forte RF injekce je steriln\u00ed vodn\u00fd roztok ur\u010den\u00fd pro pouze intramuskul\u00e1rn\u00ed pod\u00e1n\u00ed<\/strong>, obsahuj\u00edc\u00ed t\u0159i neurotropn\u00ed B-vitaminy v ka\u017ed\u00e9 2 ml ampuli:<\/p>\n

    \n
  • Methylkobalamin (vitamin B12)<\/strong> \u2014 typick\u00e1 s\u00edla 1000\u20132500 mcg<\/li>\n
  • Pyridoxin HCl (vitamin B6)<\/strong> \u2014 typick\u00e1 s\u00edla 100 mg<\/li>\n
  • Nikotinamid (vitamin B3)<\/strong> \u2014 typick\u00e1 s\u00edla 100 mg<\/li>\n<\/ul>\n

    Formulace \u201cRF\u201d je p\u0159edem p\u0159ipravena jako jedin\u00fd roztok (bez samostatn\u00fdch \u0159edic\u00edch lahvi\u010dek), co\u017e zjednodu\u0161uje pod\u00e1n\u00ed v klinick\u00e9m i dom\u00e1c\u00edm prost\u0159ed\u00ed.<\/p>\n

    Jak ka\u017ed\u00fd vitamin podporuje zdrav\u00ed nerv\u016f<\/h2>\n\n\n\n\n\n\n\n
    Vitamin<\/th>\nAktivn\u00ed forma<\/th>\n\u00daloha v nervov\u00e9 funkci<\/th>\n<\/tr>\n<\/thead>\n
    B12 (methylcobalamin)<\/td>\nJi\u017e aktivn\u00ed forma (nen\u00ed pot\u0159eba konverze v j\u00e1trech)<\/td>\nSynt\u00e9za myelinov\u00e9 pochvy, metylace DNA, odstra\u0148ov\u00e1n\u00ed homocysteinu, regenerace axon\u016f<\/td>\n<\/tr>\n
    B6 (pyridoxin)<\/td>\nPyridoxal-5-fosf\u00e1t<\/td>\nKofaktor pro synt\u00e9zu neurotransmiter\u016f (GABA, serotonin, dopamin), metabolismus sfingolipid\u016f<\/td>\n<\/tr>\n
    B3 (nikotinamid)<\/td>\nNAD \/ NADP<\/td>\nEnergetick\u00fd metabolismus, funkce mitochondri\u00ed v neuronech, ochrana p\u0159ed oxida\u010dn\u00edm stresem<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    Indikace<\/h2>\n
      \n
    • Diabetick\u00e1 perifern\u00ed neuropatie<\/strong> \u2014 zejm\u00e9na u zdokumentovan\u00e9ho nebo podez\u0159en\u00ed na nedostatek B12<\/li>\n
    • Alkoholov\u00e1 perifern\u00ed neuropatie<\/strong><\/li>\n
    • Postherpetick\u00e1 neuralgie<\/strong> \u2014 dopln\u011bk k antineuralgick\u00e9 terapii<\/li>\n
    • Ischias a radikulopatie<\/strong> \u2014 podp\u016frn\u00e1 l\u00e9\u010dba b\u011bhem akutn\u00edch epizod<\/li>\n
    • Neuralgie trojklann\u00e9ho nervu<\/strong> \u2014 dopl\u0148kov\u00fd prost\u0159edek<\/li>\n
    • Pernici\u00f3zn\u00ed an\u00e9mie<\/strong> \u2014 kdy\u017e nedostatek vnit\u0159n\u00edho faktoru br\u00e1n\u00ed peror\u00e1ln\u00ed absorpci<\/li>\n
    • N\u00e1hrada B12 po bariatrick\u00fdch v\u00fdkonech a gastrektomii<\/strong><\/li>\n
    • Megaloblastick\u00e1 an\u00e9mie<\/strong><\/li>\n
    • Bellova obrna<\/strong> \u2014 podp\u016frn\u00e1 role<\/li>\n
    • L\u00e9ky vyvolan\u00e9 neuropatie<\/strong> \u2014 isoniazid, metformin, chemoterapie<\/li>\n<\/ul>\n

      D\u00e1vkov\u00e1n\u00ed a pod\u00e1n\u00ed<\/h2>\n\n\n\n\n\n\n\n\n
      Indikace<\/th>\nNasycovac\u00ed d\u00e1vka<\/th>\nUdr\u017eovac\u00ed d\u00e1vka<\/th>\n<\/tr>\n<\/thead>\n
      Symptomatick\u00e1 neuropatie z nedostatku B-vitamin\u016f<\/td>\n1 ampule IM ka\u017ed\u00fd druh\u00fd den po dobu 2 t\u00fddn\u016f<\/td>\n1 ampule IM t\u00fddn\u011b po dobu 4\u20138 t\u00fddn\u016f, pot\u00e9 m\u011bs\u00ed\u010dn\u011b<\/td>\n<\/tr>\n
      Pernici\u00f3zn\u00ed an\u00e9mie (B12 slo\u017eka)<\/td>\n1 ampule IM ka\u017ed\u00e9 2\u20133 dny po dobu 2 t\u00fddn\u016f<\/td>\n1 ampule IM ka\u017ed\u00e9 1\u20133 m\u011bs\u00edce do\u017eivotn\u011b<\/td>\n<\/tr>\n
      Akutn\u00ed neuralgie (podp\u016frn\u00e1 l\u00e9\u010dba)<\/td>\n1 ampule IM denn\u011b po dobu 5\u201310 dn\u016f<\/td>\nN\u00e1sledn\u011b p\u0159ej\u00edt na peror\u00e1ln\u00ed B-komplex<\/td>\n<\/tr>\n
      Substituce po bariatrick\u00e9m v\u00fdkonu<\/td>\n1 ampule IM m\u011bs\u00ed\u010dn\u011b<\/td>\nDo\u017eivotn\u011b, s pravideln\u00fdmi kontrolami hladiny B12<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
      Zp\u016fsob pod\u00e1n\u00ed injekce<\/strong> Neurobion Forte RF se pod\u00e1v\u00e1 hlubokou intramuskul\u00e1rn\u00ed injekc\u00ed \u2014 obvykle do glute\u00e1ln\u00edho svalu (horn\u00ed zevn\u00ed kvadrant) nebo do deltov\u00e9ho svalu. Nesm\u00ed b\u00fdt pod\u00e1v\u00e1n intraven\u00f3zn\u011b. P\u0159ed pou\u017eit\u00edm zkontrolujte ampuli: pokud je zakalen\u00e1, zm\u011bn\u011bn\u00e9 barvy nebo obsahuje \u010d\u00e1stice, nepou\u017e\u00edvejte. Pro ka\u017edou d\u00e1vku pou\u017eijte novou steriln\u00ed st\u0159\u00edka\u010dku.<\/div>\n

      B\u011b\u017en\u00e9 ne\u017e\u00e1douc\u00ed \u00fa\u010dinky<\/h2>\n
        \n
      • M\u00edrn\u00e1 bolest, citlivost nebo zarudnut\u00ed v m\u00edst\u011b vpichu<\/li>\n
      • Nevolnost nebo m\u00edrn\u00e9 \u017ealude\u010dn\u00ed pot\u00ed\u017ee<\/li>\n
      • Bolest hlavy<\/li>\n
      • M\u00edrn\u00e9 zarudnut\u00ed<\/li>\n
      • Sv\u011btle \u010derven\u00e1 nebo na\u010dervenal\u00e1 mo\u010d po dobu 24\u201348 hodin po injekci (ne\u0161kodn\u00e9; zp\u016fsoben\u00e9 riboflavinem, pokud je p\u0159\u00edtomen, nebo metabolity B12)<\/li>\n<\/ul>\n

        V\u00e1\u017en\u00e9 vedlej\u0161\u00ed \u00fa\u010dinky \u2014 vyhledejte l\u00e9ka\u0159skou pomoc<\/h2>\n
          \n
        • Z\u00e1va\u017en\u00e1 alergick\u00e1 reakce (vyr\u00e1\u017eka, otok, obt\u00ed\u017ee s d\u00fdch\u00e1n\u00edm)<\/li>\n
        • Z\u00e1va\u017en\u00e1 reakce v m\u00edst\u011b vpichu (absces, p\u0159etrv\u00e1vaj\u00edc\u00ed bolest)<\/li>\n
        • Perifern\u00ed neuropatie vyvolan\u00e1 pyridoxinem (paradoxn\u011b p\u0159i dlouhodob\u00e9m u\u017e\u00edv\u00e1n\u00ed vysok\u00fdch d\u00e1vek B6 \u2014 typicky >200 mg\/den po m\u011bs\u00edce; relevantn\u00ed, pokud je Neurobion kombinov\u00e1n s dal\u0161\u00edmi dopl\u0148ky s vysokou d\u00e1vkou B6)<\/li>\n
        • Zarudnut\u00ed nebo zv\u00fd\u0161en\u00ed jatern\u00edch enzym\u016f vyvolan\u00e9 nikotinamidem p\u0159i vysok\u00e9 kumulativn\u00ed d\u00e1vce<\/li>\n<\/ul>\n

          Kontraindikace<\/h2>\n
            \n
          • Zn\u00e1m\u00e1 p\u0159ecitliv\u011blost na jakoukoli slo\u017eku B-vitamin\u016f nebo pomocn\u00e9 l\u00e1tky v p\u0159\u00edpravku<\/li>\n
          • Leberova heredit\u00e1rn\u00ed optick\u00e1 neuropatie (B12 m\u016f\u017ee zhor\u0161it optickou atrofii)<\/li>\n
          • Vyvarujte se u nel\u00e9\u010den\u00e9 megaloblastick\u00e9 an\u00e9mie, kde nebyl vylou\u010den pouze deficit fol\u00e1tu \u2014 n\u00e1hrada B12 bez n\u00e1hrady fol\u00e1tu m\u016f\u017ee maskovat megaloblastickou an\u00e9mii z nedostatku fol\u00e1tu<\/li>\n<\/ul>\n

            Interakce s l\u00e9\u010divy<\/h2>\n
              \n
            • Levodopa<\/strong> \u2014 pyridoxin urychluje perifern\u00ed dekarboxylaci, \u010d\u00edm\u017e sni\u017euje \u00fa\u010dinek levodopy v CNS (m\u00e9n\u011b probl\u00e9m\u016f u kombinac\u00ed levodopa-karbidopa)<\/li>\n
            • Metformin, inhibitory protonov\u00e9 pumpy, H2 blok\u00e1tory<\/strong> \u2014 sni\u017euje peror\u00e1ln\u00ed absorpci B12; intramuskul\u00e1rn\u00ed n\u00e1hrada tento probl\u00e9m obch\u00e1z\u00ed<\/li>\n
            • Fenytoin, fenobarbital, primidon<\/strong> \u2014 pyridoxin m\u016f\u017ee m\u00edrn\u011b sn\u00ed\u017eit hladiny fenytoinu; sledujte<\/li>\n
            • Chloramfenikol<\/strong> \u2014 m\u016f\u017ee oslabit hematologickou odpov\u011b\u010f na B12<\/li>\n<\/ul>\n

              Skladov\u00e1n\u00ed<\/h2>\n

              Skladujte p\u0159i teplot\u011b do 25 \u00b0C, chr\u00e1n\u011bno p\u0159ed sv\u011btlem. Nemrazte. Ampule pou\u017eijte ihned po otev\u0159en\u00ed \u2014 nevyu\u017eit\u00fd roztok zlikvidujte. Uchov\u00e1vejte mimo dosah d\u011bt\u00ed.<\/p>\n

              <\/p>\n

              Neurobion Forte RF injekce vs tablety \u2014 kdy zvolit kterou formu<\/h2>\n

              Rodina Neurobion zahrnuje jak injek\u010dn\u00ed formu (Forte RF injekce \u2014 methylkobalamin + pyridoxin + nikotinamid IM), tak peror\u00e1ln\u00ed tablety (Neurobion Forte tablety \u2014 B-komplex). Ob\u011b dod\u00e1vaj\u00ed vitaminy B pro obnovu nerv\u016f, ale hod\u00ed se pro r\u016fzn\u00e9 klinick\u00e9 situace.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
              Vlastnost<\/th>\nInjekce (tento produkt)<\/th>\nTablety<\/th>\n<\/tr>\n<\/thead>\n
              B12 (kobalamin) biologick\u00e1 dostupnost<\/td>\n~95\u2013100% \u2014 obch\u00e1z\u00ed tr\u00e1vic\u00ed trakt<\/td>\n~50% (pasivn\u00ed difuze p\u0159i vysok\u00e9 d\u00e1vce)<\/td>\n<\/tr>\n
              N\u00e1stup zlep\u0161en\u00ed nervov\u00fdch p\u0159\u00edznak\u016f<\/td>\n2\u20137 dn\u00ed<\/td>\n2\u20134 t\u00fddny<\/td>\n<\/tr>\n
              Vhodn\u00e9 pro malabsorpci (po bariatrick\u00fdch v\u00fdkonech, atrofick\u00e9 gastritid\u011b, IBD)<\/td>\nAno<\/strong> \u2014 obch\u00e1z\u00ed tr\u00e1vic\u00ed trakt<\/td>\n\u010casto nedostate\u010dn\u00e9<\/td>\n<\/tr>\n
              Vhodn\u00e9 pro vegany \/ p\u0159\u00edsn\u00e9 vegetari\u00e1ny s nedostatkem<\/td>\nAno \u2014 rychl\u00e1 korekce<\/td>\nAno \u2014 d\u00e1vka 1500 mcg\/den funguje (pasivn\u00ed difuze)<\/td>\n<\/tr>\n
              D\u00e1vkovac\u00ed sch\u00e9ma<\/td>\n3\u00d7 t\u00fddn\u011b po dobu 2\u20134 t\u00fddn\u016f \u2192 n\u00e1sledn\u00e1 udr\u017eovac\u00ed d\u00e1vka m\u011bs\u00ed\u010dn\u011b nebo dle pot\u0159eby<\/td>\nJednou denn\u011b, dlouhodob\u011b<\/td>\n<\/tr>\n
              Vhodn\u00e9 pro diabetickou perifern\u00ed neuropatii<\/td>\nPrvn\u00ed volba u st\u0159edn\u011b t\u011b\u017ek\u00fdch a\u017e t\u011b\u017ek\u00fdch p\u0159\u00edznak\u016f<\/td>\nDopl\u0148kov\u00e1 l\u00e9\u010dba nebo udr\u017eovac\u00ed terapie po injekci<\/td>\n<\/tr>\n
              Samopod\u00e1n\u00ed<\/td>\nMo\u017en\u00e9 (vy\u017eaduje \u0161kolen\u00ed v IM technice)<\/td>\nAno<\/td>\n<\/tr>\n
              N\u00e1klady za m\u011bs\u00edc<\/td>\nVy\u0161\u0161\u00ed<\/td>\nNi\u017e\u0161\u00ed<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

              Typick\u00fd re\u017eim pro diabetickou \/ alkoholickou perifern\u00ed neuropatii<\/h3>\n