<\/p>\n
Avomine<\/strong> obsahuje promethazine theoclate 25 mg<\/strong>, antihistaminikum prvn\u00ed generace s antiemetick\u00fdmi, anticholinergn\u00edmi a sedativn\u00edmi vlastnostmi. Je to zaveden\u00fd l\u00e9k prvn\u00ed volby pro kinet\u00f3zu<\/strong>, vestibul\u00e1rn\u00ed nevolnost<\/strong>, a vertiga<\/strong>, a tak\u00e9 se pou\u017e\u00edv\u00e1 k sedaci a jako dopln\u011bk p\u0159i alergi\u00edch a nevolnosti v t\u011bhotenstv\u00ed (v z\u00e1vislosti na jurisdikci). U\u017e\u00edv\u00e1 se 30\u201360 minut p\u0159ed cestou<\/strong> k profylaxi kinet\u00f3zy. Vyrobeno spole\u010dnost\u00ed Wockhardt podle standard\u016f WHO-GMP.<\/p>\n<\/div>\n \ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n Promethazine je hlavn\u00edm l\u00e9kem na kinet\u00f3zu<\/strong> \u2014 mo\u0159skou, leteckou, automobilovou i z\u00e1bavn\u00ed. Je tak\u00e9 \u00fa\u010dinn\u00fd p\u0159i vestibul\u00e1rn\u00edm vertigu<\/strong> (akutn\u00ed labyrinthitida, vestibul\u00e1rn\u00ed neuronitida, akutn\u00ed ataky Menierovy choroby) a jako sedativn\u00ed dopln\u011bk p\u0159i alergick\u00fdch reakc\u00edch nebo \u00fazkostn\u011b podm\u00edn\u011bn\u00e9 nevolnosti. Nen\u00ed l\u00e9kem prvn\u00ed volby u chemoterapi\u00ed vyvolan\u00e9 nevolnosti<\/strong> (m\u00edsto toho pou\u017eijte ondansetron\/granisetron) a nen\u00ed l\u00e9kem prvn\u00ed volby p\u0159i nevolnosti a zvracen\u00ed v t\u011bhotenstv\u00ed<\/strong> podle v\u011bt\u0161iny modern\u00edch doporu\u010den\u00ed (NVP prvn\u00ed volba je doxylamin+B6 \u2014 Doxinate, Pregnidoxin NU). N\u011bkter\u00e9 jurisdikce st\u00e1le pou\u017e\u00edvaj\u00ed promethazin u hyperemesis gravidarum po selh\u00e1n\u00ed prvn\u00ed linie.<\/p>\n Avomine je dod\u00e1v\u00e1n z v\u00fdrobce certifikovan\u00e9ho WHO-GMP<\/strong>. Ka\u017ed\u00e1 objedn\u00e1vka je diskr\u00e9tn\u011b zas\u00edl\u00e1na po cel\u00e9m sv\u011bt\u011b a je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/a> \u2014 pokud nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, provedeme p\u0159eskladn\u011bn\u00ed bez dal\u0161\u00edch n\u00e1klad\u016f. Promethazin byl po desetilet\u00ed celosv\u011btov\u00fdm standardem pro kinet\u00f3zu a z\u016fst\u00e1v\u00e1 u\u017eite\u010dn\u00fdm sedativn\u00edm antiemetikem, kdy\u017e je hlavn\u00edm probl\u00e9mem histaminergn\u00ed\/cholinergn\u00ed vestibul\u00e1rn\u00ed nevolnost.<\/p>\n Promethazin je antihistaminikum odvozen\u00e9 od fenothiazinu. Blokuje H1 histaminov\u00e9 receptory<\/strong> (antihistaminov\u00fd \u00fa\u010dinek, kter\u00fd sni\u017euje vestibul\u00e1rn\u00ed signalizaci vyvolanou pohybem a zp\u016fsobuje sedaci), muskarinov\u00fdm acetylcholinov\u00fdm receptor\u016fm<\/strong> (anticholinergn\u00ed \u00fa\u010dinek, kter\u00fd d\u00e1le potla\u010duje vestibul\u00e1rn\u00ed a st\u0159evn\u00ed motilitou vyvolan\u00e9 zvracen\u00ed), a D2 dopaminov\u00e9 receptory<\/strong> (m\u00edrn\u00fd antiemetick\u00fd \u00fa\u010dinek v oblasti chemorecep\u010dn\u00ed spou\u0161t\u011bc\u00ed z\u00f3ny). Unik\u00e1tn\u00ed hodnota promethazinu p\u0159i kinet\u00f3z\u00e1ch spo\u010d\u00edv\u00e1 v kombinovan\u00e9 blok\u00e1d\u011b H1 + anticholinergn\u00ed \u2014 vestibul\u00e1rn\u00ed syst\u00e9m z\u00e1vis\u00ed na obou t\u011bchto drah\u00e1ch. Stejn\u00e1 kombinovan\u00e1 blok\u00e1da tak\u00e9 vysv\u011btluje jeho v\u00fdrazn\u00fd sedativn\u00ed \u00fa\u010dinek a suchost v \u00fastech.<\/p>\nPro\u010d objedn\u00e1vat z MedsBase<\/h3>\n
Kdy je promethazine spr\u00e1vn\u00fdm antiemetikem<\/h2>\n
Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n
Mechanismus \u00fa\u010dinku<\/h2>\n
Indikace<\/h2>\n
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D\u00e1vka<\/h2>\n