{"id":59138,"date":"2024-02-28T05:43:27","date_gmt":"2024-02-28T05:43:27","guid":{"rendered":"https:\/\/medsname.com\/risdone-mt\/"},"modified":"2026-04-30T10:24:03","modified_gmt":"2026-04-30T10:24:03","slug":"risdone-mt","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/risdone-mt\/","title":{"rendered":"Risdone MT"},"content":{"rendered":"

<\/p>\n

\n

\u26a1 Rychl\u00e1 odpov\u011b\u010f<\/h3>\n

Risdone MT (Risperidon 0,5 mg ODT) je atypick\u00e9 antipsychotikum pro schizofrenii, bipol\u00e1rn\u00ed m\u00e1nii, podr\u00e1\u017ed\u011bnost u autismu (d\u011bti a dosp\u00edvaj\u00edc\u00ed) a kr\u00e1tkodobou agresi u demence. Nejsiln\u011bj\u0161\u00ed zv\u00fd\u0161en\u00ed prolaktinu ze v\u0161ech atypick\u00fdch \u2014 relevantn\u00ed pro plodnost, menstrua\u010dn\u00ed funkci a hustotu kost\u00ed.<\/p>\n<\/div>\n

\nCo z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n

\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n

Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n

Risdone MT na MedsBase je dod\u00e1v\u00e1n p\u0159\u00edmo od v\u00fdrobce certifikovan\u00e9ho WHO-GMP v jednoduch\u00e9m, diskr\u00e9tn\u00edm balen\u00ed. Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/a> \u2014 20pracovn\u00edchdenn\u00ed lh\u016fta pro doru\u010den\u00ed, nebo v\u00e1m z\u00e1silku zdarma p\u0159epo\u0161leme \u2014 a oprav\u0148uje v\u00e1s k \u00fa\u010dasti v na\u0161em v\u011brnostn\u00edm programu<\/a>. Dod\u00e1v\u00e1me do v\u011bt\u0161iny zem\u00ed po cel\u00e9m sv\u011bt\u011b.<\/p>\n

Co je Risdone MT a jak funguje<\/h2>\n

Risdone MT jsou orodispergovateln\u00e9 tablety risperidonu od spole\u010dnosti Sun Pharma. Dostupn\u00e9 s\u00edly: 0,5 mg ODT<\/strong>. Risperidon je siln\u00fd antagonista D2 a 5-HT2A receptor\u016f s \u03b11-adrenergn\u00ed a H1 antihistaminovou aktivitou, ale minim\u00e1ln\u00edm anticholinergn\u00edm \u00fa\u010dinkem. Siln\u00e1 blok\u00e1da D2 receptor\u016f vysv\u011btluje jak siln\u00fd antipsychotick\u00fd \u00fa\u010dinek, tak vysokou m\u00edru EPS a zv\u00fd\u0161en\u00ed prolaktinu.<\/p>\n

Formulace MT (peror\u00e1ln\u011b dispergovateln\u00e1) se rozpou\u0161t\u00ed na jazyku bez pot\u0159eby vody \u2014 vhodn\u00e9 pro akutn\u011b psychotick\u00e9 pacienty se skrytou nekomplianc\u00ed a dysfagi\u00ed.<\/p>\n

Indikace a d\u00e1vkov\u00e1n\u00ed<\/h2>\n\n\n\n\n\n\n\n\n\n
Indikace<\/th>\nPo\u010d\u00e1te\u010dn\u00ed d\u00e1vka<\/th>\nC\u00edlov\u00e1 d\u00e1vka<\/th>\nMaxim\u00e1ln\u00ed d\u00e1vka<\/th>\n<\/tr>\n<\/thead>\n
Schizofrenie (dosp\u011bl\u00ed)<\/td>\n1\u20132 mg 1\u00d7 nebo 2\u00d7 denn\u011b<\/td>\n4\u20136 mg\/den<\/td>\n16 mg<\/td>\n<\/tr>\n
Schizofrenie (dosp\u00edvaj\u00edc\u00ed \u2265 13 let)<\/td>\n0,5 mg 1\u00d7 denn\u011b<\/td>\n3 mg\/den<\/td>\n6 mg<\/td>\n<\/tr>\n
Bipol\u00e1rn\u00ed m\u00e1nie<\/td>\n2\u20133 mg 1\u00d7 denn\u011b<\/td>\n2\u20136 mg\/den<\/td>\n6 mg<\/td>\n<\/tr>\n
Podr\u00e1\u017ed\u011bnost p\u0159i autismu (d\u011bti \u2265 5 let)<\/td>\n0,25\u20130,5 mg 1\u00d7 denn\u011b<\/td>\n0,5\u20133 mg\/den dle hmotnosti<\/td>\n2,5\u20133 mg<\/td>\n<\/tr>\n
Star\u0161\u00ed pacienti\/demence (mimo indikaci, jako posledn\u00ed volba)<\/td>\n0,25 mg 1\u00d7 denn\u011b<\/td>\n0,5\u20131 mg\/den<\/td>\n2 mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

D\u016fle\u017eit\u00e9 bezpe\u010dnostn\u00ed aspekty<\/h2>\n
\nFDA black-box \u2014 psych\u00f3za spojen\u00e1 s demenc\u00ed<\/strong><\/p>\n

V\u0161echna atypick\u00e1 antipsychotika nesou varov\u00e1n\u00ed FDA black-box pro zv\u00fd\u0161enou mortalitu (p\u0159edev\u0161\u00edm kardiovaskul\u00e1rn\u00ed a infek\u010dn\u00ed) p\u0159i pou\u017eit\u00ed k l\u00e9\u010db\u011b behavior\u00e1ln\u00edch poruch u star\u0161\u00edch dosp\u011bl\u00fdch s demenc\u00ed. Atypick\u00e1 antipsychotika nejsou schv\u00e1lena pro psych\u00f3zu nebo agitovanost spojenou s demenc\u00ed<\/strong>. Pou\u017eit\u00ed u t\u00e9to populace je off-label, posledn\u00ed mo\u017enost\u00ed, \u010dasov\u011b omezen\u00e9 a vy\u017eaduje explicitn\u00ed rozhovor o rizic\u00edch a p\u0159\u00ednosech.<\/p>\n<\/div>\n

\nNejvy\u0161\u0161\u00ed zv\u00fd\u0161en\u00ed prolaktinu ze v\u0161ech atypick\u00fdch antipsychotik<\/strong><\/p>\n

Risperidon zp\u016fsobuje v\u00fdraznou, d\u00e1vkov\u011b z\u00e1vislou hyperprolaktinemii. Klinick\u00e9 d\u016fsledky:<\/strong> amenorea, galaktorea, anovulace a sn\u00ed\u017een\u00e1 hustota kost\u00ed u \u017een; ztr\u00e1ta libida, erektiln\u00ed dysfunkce a gynekomastie u mu\u017e\u016f; p\u0159i dlouhodob\u00e9m u\u017e\u00edv\u00e1n\u00ed urychlen\u00e1 osteopor\u00f3za. Zkontrolujte hladinu prolaktinu, pokud p\u0159\u00edznaky nazna\u010duj\u00ed hyperprolaktinemii. Pokud je hyperprolaktinemie symptomatick\u00e1, zva\u017ete p\u0159echod na aripiprazol (sni\u017euje prolaktin) nebo kvetiapin.<\/p>\n<\/div>\n

\nEPS \/ d\u00e1vkov\u011b z\u00e1visl\u00e9<\/strong><\/p>\n

P\u0159i d\u00e1vk\u00e1ch nad p\u0159ibli\u017en\u011b 6 mg\/den se risperidon st\u00e1le v\u00edce chov\u00e1 jako typick\u00e9 antipsychotikum z hlediska EPS \u2013 rigidita, t\u0159es, akatizie, dystonie. Riziko tardivn\u00ed dyskineze je re\u00e1ln\u00e9, ale ni\u017e\u0161\u00ed ne\u017e u typick\u00fdch antipsychotik. Pokud mo\u017eno z\u016fsta\u0148te pod 6 mg\/den.<\/p>\n<\/div>\n

\nOrtostatick\u00e1 hypotenze<\/strong><\/p>\n

\u03b11 antagonismus \u2013 \u010dast\u00fd p\u0159i zah\u00e1jen\u00ed l\u00e9\u010dby, zejm\u00e9na u star\u0161\u00edch dosp\u011bl\u00fdch. Titrujte pomalu.<\/p>\n<\/div>\n

\nMetabolick\u00e1 z\u00e1t\u011b\u017e<\/strong><\/p>\n

Men\u0161\u00ed ne\u017e u olanzapinu, ale re\u00e1ln\u00e1 \u2013 p\u0159\u00edr\u016fstek hmotnosti obvykle 2\u20134 kg za 6 m\u011bs\u00edc\u016f. Monitorujte hmotnost, hladinu gluk\u00f3zy nala\u010dno a lipidy nala\u010dno na za\u010d\u00e1tku, po 12 t\u00fddnech a pot\u00e9 ka\u017ed\u00fdch 6 m\u011bs\u00edc\u016f.<\/p>\n<\/div>\n

\u010cast\u00e9 ne\u017e\u00e1douc\u00ed \u00fa\u010dinky<\/h2>\n