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Nilol<\/strong> je fixed-dose combination of atenolol (beta-blocker) + nifedipine (dihydropyridine calcium-channel blocker)<\/strong> from a WHO-GMP certified manufacturer — widely prescribed in India and the subcontinent for combined hypertension and angina, particularly in patients where a single-drug regimen has failed. The two drugs work via complementary mechanisms: atenolol reduces cardiac output and heart rate (beta-1 blockade); nifedipine causes direct arterial vasodilation via L-type calcium channel blockade. The beta-blocker blunts the reflex tachycardia that bare nifedipine would otherwise produce. Typical dose: jedna tableta jednou denn\u011b<\/strong>. Contraindications inherit from both components: asthma \/ severe COPD \/ second-third degree heart block \/ acute heart failure \/ severe aortic stenosis \/ recent MI \/ cardiogenic shock<\/strong>.<\/p>\n<\/div>\n \ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n Nilol is an oral tablet from a WHO-GMP certified manufacturer containing:<\/p>\n The combination originated in 1980s European cardiology (brand Tenif, Tenoretic) and remains popular in India for patients with both hypertension and stable angina. The two drugs target different mechanisms: atenolol for heart-rate and contractility reduction; nifedipine for direct arterial vasodilation. The beta-blocker prevents the reflex tachycardia that nifedipine monotherapy would otherwise cause.<\/p>\n D\u00e1vkov\u00e1n\u00ed:<\/strong> one tablet once daily, usually morning. Maximum 2 tablets\/day. Target BP <140\/90 (or <130\/80 with comorbidity).<\/p>\n Monitorov\u00e1n\u00ed:<\/strong> baseline + periodic ECG (atenolol bradycardia \/ nifedipine effect on PR interval), pulse, BP, peripheral oedema (nifedipine commonly causes ankle swelling).<\/p>\n Atenolol-related:<\/strong> fatigue, cold extremities, bradycardia, exercise intolerance, mild fatigue, erectile dysfunction, masked hypoglycaemia in diabetics.<\/p>\n Nifedipine-related:<\/strong><\/p>\n Store below 25°C; protect from light.<\/p>\n Complementary mechanisms and side-effect-mitigation. Bare nifedipine causes reflex tachycardia (sympathetic response to vasodilation); atenolol blocks that reflex, giving smoother BP control. For patients with both hypertension AND stable angina, the two drugs target both diseases simultaneously.<\/p>\n Dose-related peripheral oedema occurs in up to 25% of long-term nifedipine users. It is NOT from fluid overload — it is from pre-capillary vasodilation increasing hydrostatic pressure in the lower legs. Treatment: dose reduction, leg elevation, compression stockings, or switch to a non-dihydropyridine CCB (verapamil, diltiazem) or a different vasodilator class (ACE inhibitor, ARB).<\/p>\n Atenolol is associated with intrauterine growth restriction in pregnancy (more so than other beta-blockers) and neonatal bradycardia\/hypoglycaemia. For antihypertensive use in pregnancy, labetalol<\/a>, methyldopa, and nifedipine-monotherapy (not this FDC) are the preferred options.<\/p>\n You can buy Nilol (atenolol + nifedipine 50 mg + 20 mg, 30-180 tablets) from MedsBase with discreet packaging and worldwide shipping.<\/p>\n <\/p>\n Dal\u0161\u00ed produkty v Chronick\u00e1 onemocn\u011bn\u00ed<\/strong> kter\u00e9 z\u00e1kazn\u00edci tak\u00e9 prohl\u00ed\u017eej\u00ed:<\/p>\n Nilol is a fixed-dose combination of atenolol 50 mg + nifedipine 20 mg \u2014 beta-blocker plus dihydropyridine calcium-channel blocker for combined hypertension and stable angina. Complementary mechanisms; atenolol blocks reflex tachycardia from nifedipine vasodilation. Once daily, morning. Not for pregnancy.<\/p>","protected":false},"featured_media":59418,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3260,3356],"product_tag":[3365,3390,4693],"class_list":{"0":"post-59417","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-heart-blood-pressure","9":"product_cat-high-blood-pressure-medication","10":"product_tag-atenolol","11":"product_tag-nifedipine","12":"product_tag-nilol","14":"first","15":"instock","16":"shipping-taxable","17":"purchasable","18":"product-type-variable","19":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/59417","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=59417"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/59418"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=59417"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=59417"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=59417"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=59417"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n
What Is Nilol?<\/h2>\n
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How Nilol Works<\/h2>\n
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Pou\u017eit\u00ed & D\u00e1vkov\u00e1n\u00ed<\/h2>\n
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Vedlej\u0161\u00ed \u00fa\u010dinky<\/h2>\n
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Kontraindikace<\/h2>\n
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Skladov\u00e1n\u00ed<\/h2>\n
Why combine atenolol with nifedipine?<\/h3>\n
What about the ankle swelling from nifedipine?<\/h3>\n
Why not use this in pregnancy?<\/h3>\n
Where can I buy Nilol online?<\/h3>\n
Souvisej\u00edc\u00ed beta-blok\u00e1tory a antihypertenziva<\/h2>\n
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Souvisej\u00edc\u00ed alternativy<\/h3>\n
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