{"id":60239,"date":"2024-02-28T06:40:13","date_gmt":"2024-02-28T06:40:13","guid":{"rendered":"https:\/\/medsname.com\/probiotics-25-billion-cfu\/"},"modified":"2026-04-30T10:23:49","modified_gmt":"2026-04-30T10:23:49","slug":"probiotics-25-billion-cfu","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/probiotics-25-billion-cfu\/","title":{"rendered":"Probiotika 25 miliard CFU"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Probiotics 25 Billion CFU?<\/h3>\n<p style=\"margin:0;\"><strong>Probiotika 25 miliard CFU<\/strong> is a multi-strain probiotic capsule providing <strong>25 billion colony-forming units of beneficial bacteria per dose<\/strong>, typically including Lactobacillus rhamnosus, L. acidophilus, L. plantarum, Bifidobacterium lactis, B. longum, and Streptococcus thermophilus. Probiotics support the gut microbiome and have evidence in <strong>antibiotic-associated diarrhoea (AAD), Clostridioides difficile primary prevention, infectious paediatric gastroenteritis, IBS-D, and pouchitis maintenance<\/strong>. Standardn\u00ed d\u00e1vka pro dosp\u011bl\u00e9: <strong>one capsule daily, with or after food<\/strong>. V\u00fdrobce certifikovan\u00fd WHO-GMP.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f5f6f8;border:1px solid #e1e4e8;border-radius:6px;padding:14px 18px;margin:24px 0;font-size:14px;\"><strong>Pro\u010d objedn\u00e1vat z MedsBase:<\/strong> \u2714 <strong>v\u00fdrobce certifikovan\u00e9ho WHO-GMP<\/strong> \u2714 Diskr\u00e9tn\u00ed balen\u00ed \u2714 Celosv\u011btov\u00e1 doprava \u2714 <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">Ov\u011b\u0159en\u00e9 recenze z\u00e1kazn\u00edk\u016f (1 400+ z\u00e1kazn\u00edk\u016f)<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n<div style=\"background:#f4f8fb;border-left:4px solid #2c7cb0;padding:14px 18px;margin:18px 0;border-radius:4px;\"><strong>&#128161; Probiotic evidence is strain-specific and indication-specific.<\/strong> Probiotic effects do not generalise across strains. Lactobacillus rhamnosus GG and Saccharomyces boulardii have the strongest evidence in antibiotic-associated diarrhoea. VSL#3 (8-strain blend) has the strongest evidence in pouchitis maintenance. For everyday gut-flora support a multi-strain product is reasonable; for specific clinical indications, choose a product with evidence for that indication.<\/div>\n<h3 class=\"wp-block-heading\">Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Probiotics 25 Billion CFU is supplied from a <strong>v\u00fdrobce certifikovan\u00e9ho WHO-GMP<\/strong>. Ka\u017ed\u00e1 objedn\u00e1vka je diskr\u00e9tn\u011b zas\u00edl\u00e1na po cel\u00e9m sv\u011bt\u011b a je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\">Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/a> &mdash; if it does not arrive within 20 business days, we reship at no cost. Multi-strain probiotics have the strongest evidence base when used alongside antibiotics, during foreign travel, or as supportive therapy in IBS and inflammatory bowel disease.<\/p>\n<h2 class=\"wp-block-heading\">How probiotics work<\/h2>\n<p>Probiotics colonise the gut transiently (most strains do not establish permanent residence) and exert effects through several mechanisms: competitive exclusion of pathogens at the mucosal surface, production of bacteriocins and short-chain fatty acids, modulation of mucosal immune responses (regulatory T-cell induction, IL-10 production), and direct inhibitor effects on quorum-sensing in pathogens. The effect is dose- and duration-dependent and reverts after the supplement is stopped.<\/p>\n<h2 class=\"wp-block-heading\">Best-evidence indications<\/h2>\n<table border=\"1\" cellpadding=\"6\" style=\"border-collapse:collapse;width:100%;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th>Indikace<\/th>\n<th>Strain evidence<\/th>\n<th>D\u00e1vka<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Pr\u016fjem spojen\u00fd s u\u017e\u00edv\u00e1n\u00edm antibiotik<\/td>\n<td>L. rhamnosus GG, S. boulardii<\/td>\n<td>10&ndash;25 billion CFU\/day during antibiotic course + 1 week after<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td>Acute infectious paediatric diarrhoea<\/td>\n<td>L. rhamnosus GG, S. boulardii<\/td>\n<td>5&ndash;10 billion CFU\/day for 5 days<\/td>\n<\/tr>\n<tr>\n<td>IBS (especially IBS-D)<\/td>\n<td>Bifidobacterium infantis 35624, multi-strain<\/td>\n<td>10&ndash;25 billion CFU\/day for 4&ndash;12 weeks<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td>Pouchitis maintenance<\/td>\n<td>VSL#3 8-strain<\/td>\n<td>900 billion CFU\/day (specialist supervision)<\/td>\n<\/tr>\n<tr>\n<td>Traveller&#8217;s diarrhoea (limited evidence)<\/td>\n<td>S. boulardii<\/td>\n<td>5&ndash;10 billion CFU\/day starting 5 days before travel<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td>Bacterial vaginosis recurrence (limited evidence)<\/td>\n<td>L. rhamnosus GR-1, L. reuteri RC-14<\/td>\n<td>10 billion CFU\/day for 30 days<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 class=\"wp-block-heading\">When NOT to take probiotics<\/h2>\n<ul>\n<li>Severely immunocompromised: post-stem-cell transplant, advanced HIV, severe neutropenia, central venous catheter, post-cardiac valve surgery (rare reports of fungaemia and bacteraemia)<\/li>\n<li>Severe acute pancreatitis: probiotics paradoxically increased mortality in the PROPATRIA trial; avoid in critically-ill ICU patients<\/li>\n<li>Active C. difficile infection: probiotic role is preventive, not curative; the established treatment is oral vancomycin or fidaxomicin<\/li>\n<li>Premature very-low-birth-weight neonates without specialist supervision<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">D\u00e1vka<\/h2>\n<p>One capsule daily, with or after food (food protects the bacteria from gastric acid). For antibiotic-associated diarrhoea prevention: take 2 hours after the antibiotic dose, and continue for 1 week after the antibiotic course finishes. For ongoing gut-microbiome support: one capsule daily continuously. Check pack for storage; some products require refrigeration.<\/p>\n<h2 class=\"wp-block-heading\">Vedlej\u0161\u00ed \u00fa\u010dinky<\/h2>\n<ul>\n<li>Common (first 1&ndash;2 weeks): mild flatulence, bloating, change in stool consistency &mdash; usually self-limiting<\/li>\n<li>Rare: bacteraemia or fungaemia in immunocompromised patients<\/li>\n<li>Allergic reactions to capsule excipients<\/li>\n<\/ul>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3 class=\"wp-block-heading\">When in the day should I take it?<\/h3>\n<p>With or after a meal. Food buffers stomach acid and helps more bacteria survive transit through the stomach.<\/p>\n<h3 class=\"wp-block-heading\">Mohu to u\u017e\u00edvat s antibiotiky?<\/h3>\n<p>Yes, this is the strongest-evidence use. Separate the probiotic from the antibiotic dose by 2 hours. Continue for 1 week after the antibiotic course ends.<\/p>\n<h3 class=\"wp-block-heading\">Will it cure my IBS?<\/h3>\n<p>No, but evidence supports symptom reduction in IBS-D and global IBS symptoms with multi-strain or Bifidobacterium-predominant products. Try for 4&ndash;12 weeks before judging response.<\/p>\n<h3 class=\"wp-block-heading\">Do I need to refrigerate it?<\/h3>\n<p>Check the specific pack. Many modern probiotic capsules are formulated with shelf-stable strains (no refrigeration needed); others require fridge storage to maintain CFU count.<\/p>\n<h3 class=\"wp-block-heading\">Jak rychle to zabere?<\/h3>\n<p>For antibiotic-associated diarrhoea prevention: from day 1. For IBS: 4&ndash;8 weeks. For traveller&#8217;s diarrhoea prophylaxis: start 5 days before travel.<\/p>\n<h3 class=\"wp-block-heading\">Is it safe for pregnancy?<\/h3>\n<p>Yes &mdash; multi-strain probiotics are widely considered safe in pregnancy and breastfeeding for non-immunocompromised women. Maternal probiotic use may reduce paediatric eczema risk in atopic-family pregnancies (modest evidence).<\/p>\n<h3 class=\"wp-block-heading\">M\u016f\u017eou ho u\u017e\u00edvat d\u011bti?<\/h3>\n<p>Yes. Paediatric strain choices and doses differ; check the pack age range.<\/p>\n<h3 class=\"wp-block-heading\">What about prebiotics?<\/h3>\n<p>Prebiotics (inulin, FOS, GOS) feed the gut bacteria you already have. Combining probiotics + prebiotics (a &#8220;synbiotic&#8221;) may boost effect; some products like Vizylac Rich Sachet are synbiotic by design.<\/p>\n<h3 class=\"wp-block-heading\">Skladov\u00e1n\u00ed<\/h3>\n<p>Per pack &mdash; usually below 25&deg;C in a dry place; some products require refrigeration. CFU count declines over shelf life; observe expiry dates.<\/p>\n<h3 class=\"wp-block-heading\">Co kdy\u017e vynech\u00e1m d\u00e1vku?<\/h3>\n<p>Take it when you remember. Probiotic effect is transient and continuous use is more important than catching up missed doses.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Dal\u0161\u00ed l\u00e9ky na za\u017e\u00edvac\u00ed pot\u00ed\u017ee<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/vizylac-rich-sachet\/\">Vizylac Rich Sachet &mdash; Probiotic + prebiotic + immunobiotic<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/gasex\/\">Gasex \u2014 \u00c1jurv\u00e9dsk\u00fd tr\u00e1vic\u00ed prost\u0159edek<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/dompewal-tablet\/\">Dompewal \u2014 Domperidon<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/movicol-sachets\/\">Movicol &mdash; PEG laxative<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/rifagut\/\">Rifagut \u2014 Rifaximin (st\u0159evn\u011b selektivn\u00ed antibiotikum)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/gastro-health\/\"><strong>Prohl\u00e9dnout v\u0161echny l\u00e9ky na za\u017e\u00edvac\u00ed pot\u00ed\u017ee<\/strong><\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:24px 0;border-radius:4px;\"><strong>\u2695 L\u00e9ka\u0159sk\u00e9 upozorn\u011bn\u00ed.<\/strong> This page is for informational purposes only and does not replace medical advice from a qualified healthcare professional. Severe immunocompromise, central venous catheters, severe acute pancreatitis, and active C. difficile infection require medical supervision before adding probiotics.<\/div>","protected":false},"excerpt":{"rendered":"<p>Probiotics 25 Billion CFU multi-strain capsule \u2014 L. rhamnosus \/ L. acidophilus \/ Bifidobacterium blend for antibiotic-associated diarrhoea, IBS, and gut microbiome support. WHO-GMP certified manufacturer. Worldwide shipping from MedsBase.<\/p>","protected":false},"featured_media":60240,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3542,3342],"product_tag":[4830,4831],"class_list":{"0":"post-60239","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-gastro-health","8":"product_cat-general-health","9":"product_tag-probiotics","10":"product_tag-probiotics-25-billion-cfu","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/60239","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=60239"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/60240"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=60239"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=60239"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=60239"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=60239"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}