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Stemetil MD<\/strong> je orally disintegrating tablet<\/strong> z prochlorperazine maleate 5 mg<\/strong>, a phenothiazine D2 dopamine antagonist with strong antiemetic and vestibular-suppressant action. The MD\/ODT formulation dissolves on the tongue without water, useful when active vomiting prevents reliable swallowing. Indicated for vertigo, vestibular nausea, Meniere’s disease, severe nausea, and migraine-associated nausea<\/strong>. Manufactured by Sun Pharma under WHO-GMP standards. Onset 30–60 minutes; usual dose 5 mg three times daily.<\/p>\n<\/div>\n \ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n Prochlorperazine is the first-line antiemetic for vestibular vertigo and Meniere’s symptom flare<\/strong>. It is also useful for migraine-associated nausea<\/strong> (often combined with a triptan) and for non-chemotherapy moderate nausea where 5-HT3 antagonists are not warranted. It is not first-line for chemotherapy-induced nausea<\/strong> (5-HT3 antagonists like ondansetron\/granisetron are preferred) and not first-line for nausea-vomiting of pregnancy<\/strong> (doxylamine+B6). The MD\/ODT formulation is particularly useful for acute vertigo when the patient cannot reliably swallow water.<\/p>\n Stemetil MD is supplied from a v\u00fdrobce certifikovan\u00e9ho WHO-GMP<\/strong>. Ka\u017ed\u00e1 objedn\u00e1vka je diskr\u00e9tn\u011b zas\u00edl\u00e1na po cel\u00e9m sv\u011bt\u011b a je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/a> — if it does not arrive within 20 business days, we reship at no cost. Stemetil MD is the standard ODT formulation of prochlorperazine, the established first-line drug for vestibular vertigo and Meniere’s acute attacks. The orodispersible form bypasses the swallowing problem common in active vomiting episodes.<\/p>\n Prochlorperazine is a piperazine phenothiazine. Its dominant action is D2 dopamine receptor antagonism at the chemoreceptor trigger zone<\/strong> in the area postrema, which interrupts the central emetic signal. It also has weaker H1, alpha-1, and muscarinic blockade, contributing to its anti-vertigo effect (vestibular suppression) and to side effects (sedation, hypotension, dry mouth). The phenothiazine ring structure shared with chlorpromazine explains the small risk of extrapyramidal reactions and the FDA dementia black-box warning shared with all D2 antagonist antipsychotics.<\/p>\nPro\u010d objedn\u00e1vat z MedsBase<\/h3>\n
When prochlorperazine is the right antiemetic<\/h2>\n
Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n
Mechanismus \u00fa\u010dinku<\/h2>\n
Indikace<\/h2>\n
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D\u00e1vka<\/h2>\n