{"id":60606,"date":"2024-02-28T06:58:36","date_gmt":"2024-02-28T06:58:36","guid":{"rendered":"https:\/\/medsname.com\/silvitra-120\/"},"modified":"2026-05-01T10:49:16","modified_gmt":"2026-05-01T10:49:16","slug":"silvitra-120","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/silvitra-120\/","title":{"rendered":"Silvitra 120"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Silvitra 120?<\/h3>\n<p style=\"margin:0;\"><strong>Silvitra 120<\/strong> obsahuje <strong>sildenafil 100 mg + vardenafil 20 mg<\/strong> and is used for erectile dysfunction (for men unresponsive to single-agent PDE5 inhibitors). Available in <strong>sildenafil 100 mg + vardenafil 20 mg<\/strong>. Klinick\u00fd \u00fa\u010dinek trv\u00e1 p\u0159ibli\u017en\u011b <strong>4\u20135 hodin<\/strong>. V\u00fdrobce: RSM Enterprises.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Co z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n<p><strong>Silvitra 120<\/strong> je neobvykl\u00e1 tableta kombinuj\u00edc\u00ed dva PDE5 inhibitory <strong>sildenafil 100 mg<\/strong> a <strong>vardenafil 20 mg<\/strong>. Oba jsou PDE5 inhibitory \u2014 a klinicky, <strong>PDE5 inhibitory se obvynek nekombinuj\u00ed<\/strong>. The rationale for this product is to target men who have been <strong>inadequately responsive to monotherapy<\/strong> with either drug alone, by pooling the distinct receptor-binding profiles of the two molecules.<\/p>\n<p>Manufactured by RSM Enterprises, Silvitra 120 should be used <strong>pouze pod l\u00e9ka\u0159sk\u00fdm dohledem<\/strong> because of the amplified cardiovascular and side-effect load of combining two PDE5 inhibitors.<\/p>\n<h2 class=\"wp-block-heading\">What Is Silvitra 120?<\/h2>\n<p>Silvitra 120 contains:<\/p>\n<ul>\n<li><strong>Sildenafil 100 mg<\/strong> \u2014 the classic short-acting PDE5 inhibitor; ~4-hour half-life<\/li>\n<li><strong>Vardenafil 20 mg<\/strong> \u2014 a potent PDE5 inhibitor with faster onset and robust diabetic-ED data<\/li>\n<\/ul>\n<p>The two drugs bind PDE5 with slightly different kinetics, and combining them may rescue response in men who are incomplete responders to either drug alone. This is not a first-line option \u2014 it is a <strong>z\u00e1chrann\u00fd p\u0159\u00edstup<\/strong> for hard-to-treat ED.<\/p>\n<h2 class=\"wp-block-heading\">How Does Silvitra 120 Work?<\/h2>\n<p>Ob\u011b slo\u017eky p\u016fsob\u00ed prost\u0159ednictv\u00edm stejn\u00e9 cGMP dr\u00e1hy:<\/p>\n<ul>\n<li>Sexual stimulation releases nitric oxide in penile tissue<\/li>\n<li>Oxid dusnat\u00fd aktivuje guanyl\u00e1t cykl\u00e1zu, \u010d\u00edm\u017e zvy\u0161uje hladinu cyklick\u00e9ho GMP<\/li>\n<li>cGMP relaxes smooth muscle, increasing arterial inflow<\/li>\n<li>Both sildenafil and vardenafil block PDE5, prolonging cGMP action<\/li>\n<\/ul>\n<p>Kombinace poskytuje <strong>aditivn\u00ed blok\u00e1du PDE5<\/strong> \u2014 plus each molecule&#8217;s independent receptor-binding quirks. Onset is 25\u201360 minutes, clinical window 4\u20135 hours.<\/p>\n<p><strong>Varov\u00e1n\u00ed:<\/strong> kombinace dvou inhibitor\u016f PDE5 zvy\u0161uje riziko ne\u017e\u00e1douc\u00edch \u00fa\u010dink\u016f \u2014 bolesti hlavy, n\u00e1valy horka, pokles krevn\u00edho tlaku a riziko priapismu jsou v\u00fdrazn\u011bj\u0161\u00ed. Pou\u017e\u00edvejte pouze pod p\u0159\u00edsn\u00fdm l\u00e9ka\u0159sk\u00fdm dohledem.<\/p>\n<h2 class=\"wp-block-heading\">Pou\u017eit\u00ed a indikace<\/h2>\n<ul>\n<li><strong>Erektiln\u00ed dysfunkce nereaguj\u00edc\u00ed na monoterapii inhibitorem PDE5<\/strong> \u2014 the primary and intended use<\/li>\n<li><strong>Nedoporu\u010duje se jako l\u00e9\u010dba prvn\u00ed volby<\/strong><\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Silvitra 120 Dosage and Administration<\/h2>\n<table>\n<thead>\n<tr>\n<th>Sc\u00e9n\u00e1\u0159<\/th>\n<th>Doporu\u010den\u00fd postup<\/th>\n<th>Pozn\u00e1mky<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Standardn\u00ed d\u00e1vka<\/strong><\/td>\n<td>1 tablet (sildenafil 100 + vardenafil 20) on-demand<\/td>\n<td>30\u201360 min before activity; max 1 tablet per 24 h<\/td>\n<\/tr>\n<tr>\n<td><strong>Prvn\u00ed pou\u017eit\u00ed<\/strong><\/td>\n<td>Uva\u017ete o rozd\u011blen\u00ed tablety, pokud je d\u011blen\u00e1<\/td>\n<td>Kv\u016fli riziku ne\u017e\u00e1douc\u00edch \u00fa\u010dink\u016f z kombinace dvou l\u00e9\u010div<\/td>\n<\/tr>\n<tr>\n<td><strong>Senio\u0159i (65+)<\/strong><\/td>\n<td>Nedoporu\u010duje se<\/td>\n<td>Amplified side-effect risk<\/td>\n<\/tr>\n<tr>\n<td><strong>Jatern\u00ed nebo ren\u00e1ln\u00ed insuficience<\/strong><\/td>\n<td>Nedoporu\u010duje se<\/td>\n<td>Pou\u017eijte alternativu s ni\u017e\u0161\u00ed d\u00e1vkou jednoho l\u00e9\u010diva<\/td>\n<\/tr>\n<tr>\n<td><strong>Maxim\u00e1ln\u011b<\/strong><\/td>\n<td>1 tableta ka\u017ed\u00fdch 24 hodin<\/td>\n<td>Do not combine with any other PDE5<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3 class=\"wp-block-heading\">How to Take Silvitra 120 Properly<\/h3>\n<ul>\n<li>Swallow whole with water, ideally on an empty stomach (fatty meals slow absorption of both components)<\/li>\n<li>U\u017e\u00edvejte 30\u201360 minut p\u0159ed pl\u00e1novanou aktivitou<\/li>\n<li>Do not exceed one tablet per 24 hours<\/li>\n<li><strong>Nekombinujte s \u017e\u00e1dn\u00fdm jin\u00fdm inhibitorem PDE5<\/strong><\/li>\n<li>Striktn\u011b omezte alkohol \u2014 riziko kombinovan\u00e9 vazodilatace<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Side Effects of Silvitra 120<\/h2>\n<p>Side effects are the sum of both components \u2014 and often more intense.<\/p>\n<table>\n<thead>\n<tr>\n<th>Z\u00e1va\u017enost<\/th>\n<th>Vedlej\u0161\u00ed \u00fa\u010dinek<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>B\u011b\u017en\u00e9<\/strong><\/td>\n<td>Headache (often more intense than monotherapy), flushing, nasal congestion, dyspepsia, back pain<\/td>\n<\/tr>\n<tr>\n<td><strong>M\u00e9n\u011b \u010dast\u00e9<\/strong><\/td>\n<td>Visual disturbance, dizziness, orthostatic hypotension, palpitations<\/td>\n<\/tr>\n<tr>\n<td><strong>Vz\u00e1cn\u00e9<\/strong><\/td>\n<td>Priapismus (zv\u00fd\u0161en\u00e9 riziko p\u0159i dvojit\u00e9 inhibici PDE5), n\u00e1hl\u00e1 ztr\u00e1ta zraku (NAION), n\u00e1hl\u00e1 ztr\u00e1ta sluchu<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>Varov\u00e1n\u00ed p\u0159ed priapismem:<\/strong> dvojit\u00e9 blokov\u00e1n\u00ed PDE5 nese v\u00fdznamn\u011b vy\u0161\u0161\u00ed riziko priapismu ne\u017e monoterapie. Erekc\u00ed trvaj\u00edc\u00ed d\u00e9le ne\u017e 4 hodiny je l\u00e9ka\u0159sk\u00e1 pohotovost \u2014 vyhledejte neodkladnou p\u00e9\u010di.<\/p>\n<h2 class=\"wp-block-heading\">Varov\u00e1n\u00ed a opat\u0159en\u00ed<\/h2>\n<ul>\n<li><strong>Kardiovaskul\u00e1rn\u00ed kondice pro pohlavn\u00ed styk<\/strong> \u2014 sexu\u00e1ln\u00ed aktivita klade n\u00e1roky na srdce. Mu\u017ei s aktivn\u00ed anginou pectoris, ned\u00e1vn\u00fdm infarktem myokardu (do 90 dn\u016f), nekontrolovanou arytmi\u00ed nebo t\u011b\u017ek\u00fdm srde\u010dn\u00edm selh\u00e1n\u00edm by m\u011bli p\u0159ed zah\u00e1jen\u00edm u\u017e\u00edv\u00e1n\u00ed inhibitoru PDE5 podstoupit kardiologick\u00e9 vy\u0161et\u0159en\u00ed<\/li>\n<li><strong>Krevn\u00ed tlak<\/strong> \u2014 inhibitory PDE5 zp\u016fsobuj\u00ed m\u00edrn\u00e9, p\u0159echodn\u00e9 sn\u00ed\u017een\u00ed TK; pou\u017e\u00edvejte opatrn\u011b p\u0159i u\u017e\u00edv\u00e1n\u00ed v\u00edce antihypertenziv<\/li>\n<li><strong>Priapismus<\/strong> \u2014 vy\u0161\u0161\u00ed riziko u mu\u017e\u016f se srpkovitou an\u00e9mi\u00ed, mnoho\u010detn\u00fdm myelomem nebo leuk\u00e9mi\u00ed; vyhledejte neodkladnou p\u00e9\u010di, pokud erekce trv\u00e1 d\u00e9le ne\u017e 4 hodiny<\/li>\n<li><strong>Zrak<\/strong> \u2014 p\u0159eru\u0161te u\u017e\u00edv\u00e1n\u00ed a vyhledejte l\u00e9ka\u0159e p\u0159i n\u00e1hl\u00fdch zm\u011bn\u00e1ch zraku; byly hl\u00e1\u0161eny vz\u00e1cn\u00e9 p\u0159\u00edpady nearteritick\u00e9 p\u0159edn\u00ed ischemick\u00e9 optick\u00e9 neuropatie (NAION)<\/li>\n<li><strong>Sluch<\/strong> \u2014 ojedin\u011bl\u00e9 zpr\u00e1vy o n\u00e1hl\u00e9 senzorineur\u00e1ln\u00ed ztr\u00e1t\u011b sluchu \u2014 v p\u0159\u00edpad\u011b v\u00fdskytu p\u0159eru\u0161te u\u017e\u00edv\u00e1n\u00ed a pora\u010fte se s l\u00e9ka\u0159em<\/li>\n<li><strong>Alkohol<\/strong> \u2014 v\u00fdznamn\u00fd p\u0159\u00edjem alkoholu v kombinaci s jak\u00fdmkoli inhibitorem PDE5 m\u016f\u017ee zes\u00edlit z\u00e1vrat\u011b, bolesti hlavy a n\u00edzk\u00fd krevn\u00ed tlak<\/li>\n<li><strong>Grapefruitov\u00e1 \u0161\u0165\u00e1va<\/strong> \u2014 inhibuje CYP3A4 a m\u016f\u017ee zv\u00fd\u0161it hladinu l\u00e9\u010diva v krvi<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Kontraindikace \u2014 Kdo by TENTO L\u00c9K NEM\u011aL u\u017e\u00edvat<\/h2>\n<ul>\n<li><strong>Sou\u010dasn\u00e9 u\u017e\u00edv\u00e1n\u00ed jak\u00e9hokoli nitr\u00e1tu<\/strong> \u2014 GTN, isosorbid mononitr\u00e1t\/dinitr\u00e1t, nikorandil, amylnitrit (\u201cpoppers\u201d)<\/li>\n<li><strong>Sou\u010dasn\u00e9 u\u017e\u00edv\u00e1n\u00ed stimul\u00e1tor\u016f guanyl\u00e1tcykl\u00e1zy<\/strong> jako je riociguat<\/li>\n<li>Ned\u00e1vn\u00fd infarkt myokardu (do 90 dn\u016f), nestabiln\u00ed angina pectoris nebo angina p\u0159i pohlavn\u00edm styku<\/li>\n<li>Srde\u010dn\u00ed selh\u00e1n\u00ed NYHA t\u0159\u00eddy II nebo vy\u0161\u0161\u00ed v posledn\u00edch 6 m\u011bs\u00edc\u00edch<\/li>\n<li>Nekontrolovan\u00e1 arytmie, hypotenze (TK 170\/100)<\/li>\n<li>C\u00e9vn\u00ed mozkov\u00e1 p\u0159\u00edhoda v posledn\u00edch 6 m\u011bs\u00edc\u00edch<\/li>\n<li>Prok\u00e1zan\u00e1 nearteritick\u00e1 p\u0159edn\u00ed ischemick\u00e1 optick\u00e1 neuropatie (NAION) na jednom nebo obou o\u010d\u00edch<\/li>\n<li>T\u011b\u017ek\u00e9 jatern\u00ed po\u0161kozen\u00ed (Child-Pugh C)<\/li>\n<li>P\u0159ecitliv\u011blost na \u00fa\u010dinnou l\u00e1tku nebo kteroukoli pomocnou l\u00e1tku<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Interakce s l\u00e9\u010divy<\/h2>\n<table>\n<thead>\n<tr>\n<th>L\u00e9\u010divo \/ T\u0159\u00edda<\/th>\n<th>Interakce<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Nitr\u00e1ty (GTN, ISMN, ISDN, amylnitrit\/\u201dpoppers\u201d)<\/strong><\/td>\n<td><strong>Absolutn\u00ed kontraindikace<\/strong> \u2014 z\u00e1va\u017en\u00e1, potenci\u00e1ln\u011b fat\u00e1ln\u00ed hypotenze<\/td>\n<\/tr>\n<tr>\n<td><strong>Alfa-blok\u00e1tory (doxazosin, tamsulosin, alfuzosin)<\/strong><\/td>\n<td>Aditivn\u00ed sn\u00ed\u017een\u00ed krevn\u00edho tlaku \u2014 nejprve stabilizujte d\u00e1vku alfa-blok\u00e1toru, za\u010dn\u011bte nejni\u017e\u0161\u00ed d\u00e1vkou PDE5<\/td>\n<\/tr>\n<tr>\n<td><strong>Inhibitory CYP3A4 (ketokonazol, itrakonazol, ritonavir, klarithromycin)<\/strong><\/td>\n<td>Zvy\u0161uj\u00ed hladiny PDE5 v plazm\u011b \u2014 sni\u017ete d\u00e1vkov\u00e1n\u00ed nebo se kombinaci vyhn\u011bte<\/td>\n<\/tr>\n<tr>\n<td><strong>Induktory CYP3A4 (rifampicin, fenytoin, karbamazepin, t\u0159ezalka te\u010dkovan\u00e1)<\/strong><\/td>\n<td>Sni\u017euj\u00ed hladiny PDE5 v plazm\u011b \u2014 \u00fa\u010dinnost m\u016f\u017ee b\u00fdt sn\u00ed\u017eena<\/td>\n<\/tr>\n<tr>\n<td><strong>Riociguat a dal\u0161\u00ed stimul\u00e1tory sGC<\/strong><\/td>\n<td>Kontraindikov\u00e1no \u2014 riziko t\u011b\u017ek\u00e9 hypotenze<\/td>\n<\/tr>\n<tr>\n<td><strong>Jin\u00e9 inhibitory PDE5<\/strong><\/td>\n<td>Nekombinujte \u2014 aditivn\u00ed vedlej\u0161\u00ed \u00fa\u010dinky bez zv\u00fd\u0161en\u00ed \u00fa\u010dinnosti<\/td>\n<\/tr>\n<tr>\n<td><strong>Antihypertenziva<\/strong><\/td>\n<td>Mal\u00fd aditivn\u00ed pokles TK \u2014 obvykle klinicky nev\u00fdznamn\u00fd<\/td>\n<\/tr>\n<tr>\n<td><strong>Grapefruitov\u00e1 \u0161\u0165\u00e1va<\/strong><\/td>\n<td>Inhibuje CYP3A4 \u2014 vyvarujte se velk\u00e9ho nebo pravideln\u00e9ho p\u0159\u00edjmu<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>P\u0159ed zah\u00e1jen\u00edm u\u017e\u00edv\u00e1n\u00ed tohoto l\u00e9ku v\u017edy sd\u011blte sv\u00e9mu p\u0159edepisuj\u00edc\u00edmu l\u00e9ka\u0159i \u00fapln\u00fd seznam sou\u010dasn\u011b u\u017e\u00edvan\u00fdch l\u00e9k\u016f, v\u010detn\u011b voln\u011b prodejn\u00fdch p\u0159\u00edpravk\u016f, rekrea\u010dn\u00edch drog a bylinn\u00fdch dopl\u0148k\u016f.<\/p>\n<h2 class=\"wp-block-heading\">Co d\u011blat v p\u0159\u00edpad\u011b p\u0159ed\u00e1vkov\u00e1n\u00ed<\/h2>\n<p>P\u0159\u00edznaky p\u0159ed\u00e1vkov\u00e1n\u00ed PDE5 zahrnuj\u00ed silnou bolest hlavy, v\u00fdraznou hypotenzi, z\u00e1vrat\u011b, bolest zad nebo sval\u016f a prodlou\u017eenou erekci. L\u00e9\u010dba je podp\u016frn\u00e1, s resuscitac\u00ed tekutinami a monitorov\u00e1n\u00edm srde\u010dn\u00ed \u010dinnosti. Pokud m\u00e1te podez\u0159en\u00ed na p\u0159ed\u00e1vkov\u00e1n\u00ed, okam\u017eit\u011b kontaktujte m\u00edstn\u00ed toxikologick\u00e9 st\u0159edisko nebo pohotovost.<\/p>\n<h2 class=\"wp-block-heading\">Pokyny k uchov\u00e1v\u00e1n\u00ed<\/h2>\n<ul>\n<li>Skladujte pod 30 \u00b0C na such\u00e9m m\u00edst\u011b, mimo p\u0159\u00edm\u00e9 slune\u010dn\u00ed sv\u011btlo<\/li>\n<li>Uchov\u00e1vejte v p\u016fvodn\u00edm blistru a\u017e do pou\u017eit\u00ed<\/li>\n<li>Uchov\u00e1vejte mimo dosah d\u011bt\u00ed a dom\u00e1c\u00edch zv\u00ed\u0159at<\/li>\n<li>Nepou\u017e\u00edvejte po datu expirace uveden\u00e9m na obalu<\/li>\n<li>Nepou\u017eit\u00e9 tablety likvidujte prost\u0159ednictv\u00edm l\u00e9k\u00e1rny, pokud je k dispozici<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Souvisej\u00edc\u00ed alternativy na MedsBase<\/h2>\n<p>Hled\u00e1te souvisej\u00edc\u00ed mo\u017enosti l\u00e9\u010dby ED nebo sexu\u00e1ln\u00edho zdrav\u00ed?<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/modula\/\" rel=\"noopener\">Modula<\/a> \u2014 tadalafil 5 mg, ide\u00e1ln\u00ed pro jednou denn\u00ed n\u00edzkou d\u00e1vku<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/vidalista\/\" rel=\"noopener\">Vidalista<\/a> \u2014 Centurion Labs tadalafil, 2,5 a\u017e 80 mg<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/tadacip\/\" rel=\"noopener\">Tadacip<\/a> \u2014 Cipla tadalafil 20 mg<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/megalis\/\" rel=\"noopener\">Megalis<\/a> \u2014 Macleods tadalafil 10 mg \/ 20 mg<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/suhagra\/\" rel=\"noopener\">Suhagra<\/a> \u2014 Cipla sildenafil 25\/50\/100 mg<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/erectile-dysfunction\/\" rel=\"noopener\">Prohl\u00e9dnout v\u0161echny l\u00e9\u010debn\u00e9 p\u0159\u00edpravky na erektiln\u00ed dysfunkci \u2192<\/a><\/li>\n<\/ul>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3 class=\"wp-block-heading\">Why would anyone combine two PDE5 inhibitors?<\/h3>\n<p>Dual PDE5 therapy is a <strong>z\u00e1chrann\u00fd p\u0159\u00edstup<\/strong> for men who have been incomplete responders to single-agent treatment. The two molecules have slightly different receptor-binding profiles, and combining them can rescue response. It is not a first-line option.<\/p>\n<h3 class=\"wp-block-heading\">Is Silvitra 120 safe?<\/h3>\n<p>Only under medical supervision. Stacking two PDE5 inhibitors amplifies cardiovascular, visual, and priapism risks. Do not use this product if you have not already trialled single-agent PDE5 therapy with guidance.<\/p>\n<h3 class=\"wp-block-heading\">How long does Silvitra 120 last?<\/h3>\n<p>About 4\u20135 hours \u2014 limited by vardenafil&#8217;s half-life. Sildenafil contributes a similar window.<\/p>\n<h3 class=\"wp-block-heading\">Who should NOT take Silvitra 120?<\/h3>\n<p>Pacienti s ED, kte\u0159\u00ed nevyzkou\u0161eli monoterapii. Mu\u017ei nad 65 let. Ka\u017ed\u00fd se srde\u010dn\u00edm onemocn\u011bn\u00edm, jatern\u00ed nebo ren\u00e1ln\u00ed nedostate\u010dnost\u00ed nebo u\u017e\u00edvaj\u00edc\u00ed nitr\u00e1ty. Ka\u017ed\u00fd, kdo u\u017e\u00edv\u00e1 dal\u0161\u00ed inhibitor PDE5 nebo l\u00e9k inhibuj\u00edc\u00ed CYP3A4.<\/p>\n<h3 class=\"wp-block-heading\">What if Silvitra 120 causes a bad headache?<\/h3>\n<p>Bolest hlavy je mnohem \u010dast\u011bj\u0161\u00ed u kombinace dvou inhibitor\u016f PDE5 ne\u017e u monoterapie. Pokud p\u0159etrv\u00e1v\u00e1 nebo je siln\u00e1, p\u0159ejd\u011bte na monoterapii \u2014 bu\u010f sildenafil (<a href=\"https:\/\/medsbase.com\/cs\/suhagra\/\" rel=\"noopener\">Suhagra<\/a>, <a href=\"https:\/\/medsbase.com\/cs\/malegra\/\" rel=\"noopener\">Malegra<\/a>) or vardenafil (<a href=\"https:\/\/medsbase.com\/cs\/zhewitra\/\" rel=\"noopener\">Zhewitra<\/a>) v standardn\u00ed d\u00e1vce.<\/p>\n<h3 class=\"wp-block-heading\">Is there a simpler alternative?<\/h3>\n<p>For most men: yes. Try <a href=\"https:\/\/medsbase.com\/cs\/modula\/\" rel=\"noopener\">tadalafil<\/a> nebo <a href=\"https:\/\/medsbase.com\/cs\/avana\/\" rel=\"noopener\">avanafil<\/a> as single-agent options before resorting to dual PDE5. These work in many sildenafil or vardenafil non-responders.<\/p>\n<h3 class=\"wp-block-heading\">Can I drink alcohol with Silvitra 120?<\/h3>\n<p>Strictly limit alcohol. Dual PDE5 amplifies vasodilation; alcohol compounds the risk of dizziness, fainting, and severe headache.<\/p>\n<h3 class=\"wp-block-heading\">Does Silvitra 120 work for diabetic ED?<\/h3>\n<p>Possibly \u2014 the vardenafil component has strong diabetic-ED data. However, a single-agent vardenafil trial should precede combination therapy.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Silvitra 120 daily?<\/h3>\n<p>No \u2014 on-demand only, max once per 24 hours. For daily dosing, tadalafil 5 mg (<a href=\"https:\/\/medsbase.com\/cs\/modula\/\" rel=\"noopener\">Modula<\/a>) is the only licensed option.<\/p>\n<h3 class=\"wp-block-heading\">What if Silvitra 120 doesn&#8217;t work?<\/h3>\n<p>Pokud du\u00e1ln\u00ed inhibice PDE5 sel\u017ee, dal\u0161\u00edm krokem je doporu\u010den\u00ed ke specialistovi-urologovi. Mezi mo\u017enosti mimo peror\u00e1ln\u00ed terapii pat\u0159\u00ed nitrokavern\u00f3zn\u00ed injekce (alprostadil), vakuov\u00e1 erek\u010dn\u00ed za\u0159\u00edzen\u00ed nebo peniln\u00ed implant\u00e1ty.<\/p>\n<p><!-- medsbase-faq-h3-converted --><\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Souvisej\u00edc\u00ed alternativy<\/h3>\n<p>Dal\u0161\u00ed produkty v <strong>Mu\u017esk\u00e9 zdrav\u00ed<\/strong> kter\u00e9 z\u00e1kazn\u00edci tak\u00e9 prohl\u00ed\u017eej\u00ed:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/sildalist\/\">Sildalist<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/androtas-gel-5gm\/\">Androtas Gel 5gm<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/cenforce\/\">Cenforce<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/tentex-royal\/\">Tentex Royal<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/abhigra\/\">Abhigra<\/a><\/li>\n<\/ul>\n<p><!-- medsbase-guide-ed-hub --><\/p>\n<p style=\"margin:20px 0 0;padding:12px 16px;background:#f4f8fb;border-left:3px solid #2c7cb0;border-radius:3px;font-size:14px\">\ud83d\udcda <strong>Porovnejte v\u0161echny l\u00e9ky na ED:<\/strong> <a href=\"https:\/\/medsbase.com\/cs\/best-medicine-for-erectile-dysfunction-without-side-effects\/\">N\u00e1kup l\u00e9k\u016f na ED online (2026): Top 10 porovn\u00e1no podle ceny, n\u00e1stupu \u00fa\u010dinku a d\u00e9lky \u00fa\u010dinku<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>\u2705 Dvojit\u00fd \u00fa\u010dinek<br \/>\n\u2705 L\u00e9\u010d\u00ed erektiln\u00ed dysfunkci<br \/>\n\u2705 Zlep\u0161uje sexu\u00e1ln\u00ed v\u00fdkonnost<br \/>\n\u2705 Zvy\u0161uje v\u00fddr\u017e<br \/>\n\u2705 Zlep\u0161uje spokojenost<\/p>\n<p>Silvitra contains Sildenafil &amp; Vardenafil.<\/p>","protected":false},"featured_media":60607,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3143,3142,3151,3292],"product_tag":[5660,5635,5661,3153,4888,5662,3294],"class_list":{"0":"post-60606","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-erectile-dysfunction","8":"product_cat-mens-health","9":"product_cat-sildenafil","10":"product_cat-vardenafil","11":"product_tag-dual-pde5","12":"product_tag-erectile-dysfunction","13":"product_tag-salvage-therapy","14":"product_tag-sildenafil","15":"product_tag-silvitra","16":"product_tag-treatment-resistant-ed","17":"product_tag-vardenafil","19":"first","20":"instock","21":"shipping-taxable","22":"purchasable","23":"product-type-variable","24":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/60606","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=60606"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/60607"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=60606"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=60606"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=60606"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=60606"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}