{"id":60815,"date":"2024-02-28T07:10:05","date_gmt":"2024-02-28T07:10:05","guid":{"rendered":"https:\/\/medsname.com\/thiamine-hcl-100\/"},"modified":"2026-04-30T10:23:42","modified_gmt":"2026-04-30T10:23:42","slug":"thiamine-hcl-100","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/thiamine-hcl-100\/","title":{"rendered":"Thiamin HCL 100"},"content":{"rendered":"<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<h3 style=\"margin-top:0;\">Rychl\u00e1 odpov\u011b\u010f<\/h3>\n<p><strong>Thiamine HCL 100 (thiamine (vitamin B1) 100 mg tablet)<\/strong> is high-dose oral thiamine for treatment of thiamine deficiency, alcohol-related neuropathy, beriberi, and as Wernicke prophylaxis at risk patients.<\/p>\n<ul style=\"margin-bottom:0;\">\n<li>Thiamine 100 mg per tablet &mdash; full replacement strength<\/li>\n<li>Indications: alcohol use disorder, refeeding syndrome prophylaxis, beriberi, hyperemesis<\/li>\n<li>Long-term oral 100&ndash;200 mg\/day for chronic deficiency or alcohol use disorder<\/li>\n<li>v\u00fdrobce certifikovan\u00e9ho WHO-GMP<\/li>\n<\/ul>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f6f8;border:1px solid #e0e4e7;padding:12px 16px;margin:18px 0;border-radius:4px;font-size:14px;color:#444;\">\n<strong>v\u00fdrobce certifikovan\u00e9ho WHO-GMP<\/strong> \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\" style=\"color:#2c7cb0;\">1 400+ ov\u011b\u0159en\u00fdch recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<p style=\"font-size:13px;color:#666;margin:4px 0 18px;\">Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00edm <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\" style=\"color:#2c7cb0;\">Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/a>.<\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Thiamine HCL 100 is sourced from a WHO-GMP certified manufacturer. Every order ships in discreet, unbranded packaging worldwide and is covered by our Reshipment Assurance Policy. Pay securely with credit card, SEPA bank transfer, or cryptocurrency. See our <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">1 400+ ov\u011b\u0159en\u00fdch recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>.<\/p>\n<h2>What is Thiamine HCL 100?<\/h2>\n<p>Thiamine HCL 100 is high-dose oral thiamine (vitamin B1) for replacement and maintenance therapy in deficiency. Thiamine is a coenzyme essential for carbohydrate metabolism (pyruvate dehydrogenase, transketolase, alpha-ketoglutarate dehydrogenase). Deficiency causes wet beriberi (high-output cardiac failure), dry beriberi (peripheral neuropathy), and Wernicke-Korsakoff syndrome.<\/p>\n<h2>Indikace<\/h2>\n<ul>\n<li><strong>Porucha u\u017e\u00edv\u00e1n\u00ed alkoholu<\/strong> &mdash; multi-decade chronic alcohol intake regularly causes deficiency. Long-term oral 100 mg twice daily is standard.<\/li>\n<li><strong>Wernicke-Korsakoff syndrome<\/strong> &mdash; classical triad of confusion, ataxia, ophthalmoplegia in alcohol-dependent or hyperemetic patients. Acute treatment is parenteral high-dose thiamine; oral 100 mg twice daily is for prevention and post-acute maintenance.<\/li>\n<li><strong>Beriberi<\/strong> &mdash; rare in food-secure populations; still seen in alcohol-dependent and severely malnourished patients<\/li>\n<li><strong>Refeeding syndrome prophylaxis<\/strong> &mdash; prior to refeeding any malnourished patient (anorexia, severe undernutrition, prolonged fasting), give parenteral thiamine first then oral maintenance<\/li>\n<li><strong>Hyperemesis gravidarum<\/strong> &mdash; pregnancy-related severe vomiting depletes thiamine; replacement protects against Wernicke&#8217;s<\/li>\n<li><strong>Chronic loop diuretic use<\/strong> with heart failure (loop diuretics deplete thiamine; supplementation has modest evidence in advanced heart failure)<\/li>\n<li><strong>Post-bariatric maintenance<\/strong><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<strong>Suspected Wernicke&#8217;s encephalopathy needs PARENTERAL high-dose thiamine first<\/strong><\/p>\n<p style=\"margin-bottom:0;\">Oral thiamine 100 mg\/tablet is appropriate for prevention and chronic maintenance. In suspected acute Wernicke&#8217;s encephalopathy (confusion, ataxia, ophthalmoplegia &mdash; especially in alcohol-dependent patients, hyperemesis, post-bariatric, or refeeding) the standard is IV thiamine 500 mg three times daily for 2&ndash;3 days then 250 mg\/day &mdash; oral is too slow and absorption is unreliable in this group. Never give glucose or carbohydrate to a thiamine-deficient patient before thiamine is replaced &mdash; this can precipitate Wernicke&#8217;s.<\/p>\n<\/div>\n<h3>D\u00e1vka<\/h3>\n<ul>\n<li><strong>Maintenance in alcohol use disorder<\/strong>: 100 mg orally twice daily long-term<\/li>\n<li><strong>Beriberi<\/strong>: 100&ndash;300 mg\/day in divided doses for several weeks, then maintenance<\/li>\n<li><strong>Refeeding prophylaxis<\/strong>: parenteral first; oral 100 mg twice daily during refeeding period<\/li>\n<li><strong>Hyperemesis gravidarum<\/strong>: parenteral thiamine 100 mg, then oral if tolerated<\/li>\n<li><strong>Heart failure on loop diuretic<\/strong>: 100 mg\/day oral<\/li>\n<\/ul>\n<h2>Vedlej\u0161\u00ed \u00fa\u010dinky<\/h2>\n<ul>\n<li><strong>Generally very well tolerated<\/strong> &mdash; oral thiamine has an exceptional safety profile<\/li>\n<li><strong>Anaphylaxis<\/strong> &mdash; rare and almost exclusively reported with parenteral thiamine, not oral<\/li>\n<li><strong>M\u00edrn\u00e9 za\u017e\u00edvac\u00ed pot\u00ed\u017ee<\/strong> p\u0159i vysok\u00fdch d\u00e1vk\u00e1ch<\/li>\n<\/ul>\n<h2>Interakce l\u00e9k\u016f<\/h2>\n<p>Thiamine has no significant clinically relevant drug interactions. Loop diuretics deplete thiamine but supplementation does not interfere with diuretic action.<\/p>\n<h2>Kontraindikace<\/h2>\n<ul>\n<li>Hypersensitivity to thiamine (rare)<\/li>\n<\/ul>\n<h2>Skladov\u00e1n\u00ed<\/h2>\n<p>Skladujte p\u0159i teplot\u011b pod 25 \u00b0C v p\u016fvodn\u00edm obalu, chra\u0148te p\u0159ed vlhkost\u00ed.<\/p>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3>Why is thiamine so important in alcohol use?<\/h3>\n<p>Alcohol impairs thiamine absorption, increases urinary loss, and competes with thiamine-dependent enzymes. Long-term alcohol use causes Wernicke&#8217;s encephalopathy (acute, reversible if treated early) and Korsakoff psychosis (chronic, partially reversible). Both are essentially preventable with adequate thiamine.<\/p>\n<h3>Should I take thiamine if I drink heavily?<\/h3>\n<p>If you cannot or will not stop drinking, oral thiamine 100 mg twice daily reduces the risk of Wernicke&#8217;s &mdash; this is genuinely worth doing, even alongside ongoing drinking. Stopping alcohol is the actual treatment, but thiamine offers concrete protection while you work toward that.<\/p>\n<h3>What is refeeding syndrome?<\/h3>\n<p>Severe malnourishment depletes phosphate, magnesium, potassium, and thiamine. When carbohydrate refeeding starts, insulin surges and these intracellular shifts intensify, causing fatal arrhythmias, heart failure, and Wernicke&#8217;s. Refeeding always includes thiamine first, slow caloric increase, and electrolyte correction.<\/p>\n<h3>Can I take it without a deficiency?<\/h3>\n<p>Yes &mdash; thiamine has a wide safety margin and excess is excreted. Routine megadose without indication is pointless but harmless.<\/p>\n<h3>Jak rychle \u00fa\u010dinkuje?<\/h3>\n<p>Acute Wernicke&#8217;s (with parenteral thiamine): ophthalmoplegia improves within hours, ataxia over days, confusion over days-to-weeks. Chronic alcoholic neuropathy: slow improvement over months, often incomplete. Beriberi cardiac symptoms: hours-to-days.<\/p>\n<h3>Je bezpe\u010dn\u00fd v t\u011bhotenstv\u00ed?<\/h3>\n<p>Yes &mdash; safe and important in hyperemesis gravidarum to prevent Wernicke&#8217;s. The B6 + B12 + thiamine combination in nausea-of-pregnancy management is well established.<\/p>\n<h3>Should I take it with B-complex?<\/h3>\n<p>B-complex preparations contain thiamine but at lower doses. For prevention and maintenance, B-complex is sufficient. For active deficiency or alcohol use disorder, dedicated 100 mg thiamine is preferred &mdash; the dose in standard B-complex (often 5&ndash;20 mg) is below the therapeutic threshold for these indications.<\/p>\n<h3>Why does my doctor give parenteral thiamine in the ED?<\/h3>\n<p>Acute Wernicke&#8217;s suspicion needs parenteral high-dose thiamine because (a) oral absorption is impaired in alcohol-dependent patients, (b) gut absorption is slow when minutes matter, and (c) carbohydrate-containing IV fluids are likely to be given anyway and these can precipitate Wernicke&#8217;s in deficient patients without prior thiamine cover.<\/p>\n<h3>Will it help my fatigue?<\/h3>\n<p>Only if fatigue is from documented thiamine deficiency. Most fatigue is not from thiamine; check thyroid, ferritin, vitamin D, B12, depression, sleep apnoea first.<\/p>\n<h3>How long should I take it?<\/h3>\n<p>In alcohol use disorder, lifelong supplementation is reasonable while drinking continues and for at least a year after sobriety. Otherwise, until the underlying cause (malnutrition, refeeding, hyperemesis) resolves.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h2>Ostatn\u00ed vitam\u00edny a miner\u00e1ly<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/vitamin-b12-1500-mcg-tablets-nerve-health-energy\/\">Vitamin B12 1500 mcg<\/a> \u2014 vysokod\u00e1vkovan\u00fd peror\u00e1ln\u00ed kyanokobalamin<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/walcobal-injection\/\">Walcobal Injekce<\/a> \u2014 methylkobalamin IM<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/polybion-ampoule\/\">Polybion Ampule<\/a> \u2014 parenter\u00e1ln\u00ed B-komplex<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/beplex-forte\/\">Beplex Forte<\/a> \u2014 peror\u00e1ln\u00ed B-komplex<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/becozinc\/\">Becozinc<\/a> \u2014 B-komplex se zinkem<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/thiamine-hcl-100\/\">Thiamin HCL 100<\/a> \u2014 thiamin 100 mg pro alkoholovou neuropatii<\/li>\n<\/ul>\n<h2>L\u00e9ka\u0159sk\u00e9 upozorn\u011bn\u00ed<\/h2>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;color:#444;\">\nTato str\u00e1nka slou\u017e\u00ed pouze pro vzd\u011bl\u00e1vac\u00ed \u00fa\u010dely a nenahrazuje odbornou l\u00e9ka\u0159skou pomoc. Dopln\u011bn\u00ed vitam\u00edn\u016f a miner\u00e1l\u016f by m\u011blo b\u00fdt ide\u00e1ln\u011b vedeno laboratorn\u00edmi testy, pokud je podez\u0159en\u00ed na nedostatek. Megad\u00e1vky dopl\u0148k\u016f nejsou ne\u0161kodn\u00e9 \u2014 vitamin A je teratogenn\u00ed, vitamin E zvy\u0161uje riziko krv\u00e1cen\u00ed, beta-karoten zvy\u0161uje riziko rakoviny plic u ku\u0159\u00e1k\u016f a vysok\u00e9 d\u00e1vky v\u00e1pn\u00edku maj\u00ed kardiovaskul\u00e1rn\u00ed \u00fa\u010dinky. T\u011bhotn\u00e9 nebo koj\u00edc\u00ed pacientky by m\u011bly dodr\u017eovat doporu\u010den\u00ed pro prenat\u00e1ln\u00ed suplementaci. Pacienti u\u017e\u00edvaj\u00edc\u00ed warfarin mus\u00ed udr\u017eovat stabiln\u00ed p\u0159\u00edjem vitaminu K. Pacienti u\u017e\u00edvaj\u00edc\u00ed levothyroxin, fluorochinolony nebo tetracykliny mus\u00ed odd\u011blit p\u0159\u00edjem \u017eeleza a v\u00e1pn\u00edku o 4 hodiny. V\u017edy informujte sv\u00e9ho l\u00e9ka\u0159e a l\u00e9k\u00e1rn\u00edka o v\u0161ech dopl\u0148c\u00edch stravy.\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u2705 Zvy\u0161uje energetickou hladinu<br \/>\n\u2705 Supports nerve function<br \/>\n\u2705 Improves metabolism<br \/>\n\u2705 Zlep\u0161uje kognitivn\u00ed funkce<br \/>\n\u2705 Promotes heart health<\/p>\n<p>Thiamine HCL 100 contains Thiamine.<\/p>","protected":false},"featured_media":60816,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3342,3863],"product_tag":[4929,4930],"class_list":{"0":"post-60815","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-general-health","8":"product_cat-vitamins-and-minerals","9":"product_tag-thiamine","10":"product_tag-vitamin-b1","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/60815","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=60815"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/60816"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=60815"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=60815"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=60815"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=60815"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}