{"id":61275,"date":"2024-02-28T07:32:55","date_gmt":"2024-02-28T07:32:55","guid":{"rendered":"https:\/\/medsname.com\/vitamin-b12\/"},"modified":"2026-05-01T10:49:16","modified_gmt":"2026-05-01T10:49:16","slug":"vitamin-b12","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/vitamin-b12\/","title":{"rendered":"Tablety s vitaminem B12 1500 mcg \u2014 zdrav\u00ed nerv\u016f a energie"},"content":{"rendered":"
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Rychl\u00e1 odpov\u011b\u010f<\/h3>\n

Tablety s vitaminem B12 1500 mcg<\/strong> poskytuj\u00ed vysokou d\u00e1vku or\u00e1ln\u00edho kyanokobalaminu (nebo methylkobalaminu v n\u011bkter\u00fdch formulac\u00edch) k l\u00e9\u010db\u011b a prevenci nedostatku vitaminu B12 \u2013 \u010dast\u00e9, ale \u010dasto p\u0159ehl\u00ed\u017een\u00e9 p\u0159\u00ed\u010diny perifern\u00ed neuropatie, megaloblastick\u00e9 an\u00e9mie, \u00fanavy a kognitivn\u00edch p\u0159\u00edznak\u016f. D\u00e1vka 1500 mcg je vhodn\u00e1 pro n\u00e1hradu p\u0159i m\u00edrn\u00e9m a\u017e st\u0159edn\u00edm nedostatku, dlouhodobou udr\u017eovac\u00ed l\u00e9\u010dbu po parenter\u00e1ln\u00edm nasycen\u00ed a b\u011b\u017enou podporu u rizikov\u00fdch skupin: vegan\u016f a vegetari\u00e1n\u016f, dosp\u011bl\u00fdch nad 60 let, pacient\u016f dlouhodob\u011b u\u017e\u00edvaj\u00edc\u00edch metformin nebo inhibitory protonov\u00e9 pumpy, po bariatrick\u00fdch operac\u00edch a u osob s atrofickou gastritidou. U\u017e\u00edvejte jednu tabletu denn\u011b s vodou. I pacienti s pernici\u00f3zn\u00ed an\u00e9mi\u00ed mohou absorbovat malou \u010d\u00e1st vysok\u00e9 d\u00e1vky or\u00e1ln\u00edho B12 pasivn\u00ed dif\u00faz\u00ed, co\u017e \u010din\u00ed 1500 mcg \u00fa\u010dinnou alternativou k m\u011bs\u00ed\u010dn\u00edm injekc\u00edm v mnoha p\u0159\u00edpadech.<\/p>\n<\/div>\n

\nCo z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n

\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n

Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n

Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n

Co je vitamin B12?<\/h2>\n

Vitamin B12 (kobalamin) je ve vod\u011b rozpustn\u00fd vitamin nezbytn\u00fd pro synt\u00e9zu DNA, tvorbu \u010derven\u00fdch krvinek, tvorbu myelinu a metabolismus homocysteinu<\/strong>. Lid\u00e9 si B12 neum\u011bj\u00ed syntetizovat \u2013 ve\u0161ker\u00fd dietn\u00ed B12 poch\u00e1z\u00ed z \u017eivo\u010di\u0161n\u00fdch potravin (maso, ryby, vejce, ml\u00e9\u010dn\u00e9 v\u00fdrobky) nebo obohacen\u00fdch rostlinn\u00fdch potravin. Tableta s 1500 mcg poskytuje vysokou d\u00e1vku or\u00e1ln\u00ed n\u00e1hrady, kter\u00e1 n\u011bkolikan\u00e1sobn\u011b p\u0159ekra\u010duje doporu\u010den\u00fd denn\u00ed p\u0159\u00edjem (2,4 mcg), a vyu\u017e\u00edv\u00e1 pasivn\u00ed dif\u00fazi k absorpci B12 i p\u0159i nedostatku vnit\u0159n\u00edho faktoru (gastrick\u00e9ho proteinu pot\u0159ebn\u00e9ho pro aktivn\u00ed absorpci).<\/p>\n

Pro\u010d funguj\u00ed vysok\u00e9 d\u00e1vky B12 v tablet\u00e1ch bez injekc\u00ed<\/h2>\n

T\u011blo absorbuje B12 dv\u011bma zp\u016fsoby:<\/p>\n

    \n
  • Aktivn\u00ed absorpce zprost\u0159edkovan\u00e1 vnit\u0159n\u00edm faktorem<\/strong> \u2013 \u00fa\u010dinn\u00e1, ale omezen\u00e1 na p\u0159ibli\u017en\u011b 1\u20132 mcg na d\u00e1vku, vy\u017eaduje zdrav\u00e9 pariet\u00e1ln\u00ed bu\u0148ky \u017ealudku a ileum<\/li>\n
  • Pasivn\u00ed dif\u00faze<\/strong> \u2013 ne\u00fa\u010dinn\u00e1 (\u22481% d\u00e1vky), ale \u00fam\u011brn\u00e1 or\u00e1ln\u00ed d\u00e1vce; nevy\u017eaduje vnit\u0159n\u00ed faktor<\/li>\n<\/ul>\n

    P\u0159i d\u00e1vce 1500 mcg na tabletu pasivn\u00ed dif\u00faze samotn\u00e1 dod\u00e1 p\u0159ibli\u017en\u011b 15 mcg \u2013 co\u017e v\u00fdrazn\u011b p\u0159ekra\u010duje denn\u00ed pot\u0159ebu. \u010cetn\u00e9 randomizovan\u00e9 studie prok\u00e1zaly, \u017ee vysokod\u00e1vkovan\u00fd peror\u00e1ln\u00ed B12 (1000\u20132000 mcg\/den) nen\u00ed hor\u0161\u00ed ne\u017e m\u011bs\u00ed\u010dn\u00ed intramuskul\u00e1rn\u00ed injekce p\u0159i udr\u017eovac\u00ed terapii, v\u010detn\u011b pernici\u00f3zn\u00ed an\u00e9mie.<\/p>\n

    Indikace<\/h2>\n
      \n
    • Deficit vitaminu B12<\/strong> \u2014 symptomatick\u00e9 nebo biochemick\u00e9 (s\u00e9rov\u00fd B12 <200 pg\/ml, nebo 200\u2013300 pg\/ml se zv\u00fd\u0161enou hladinou methylmalonov\u00e9 kyseliny \/ homocysteinu)<\/li>\n
    • Udr\u017eovac\u00ed l\u00e9\u010dba pernici\u00f3zn\u00ed an\u00e9mie<\/strong> \u2014 po parenter\u00e1ln\u00ed nasycovac\u00ed l\u00e9\u010db\u011b<\/li>\n
    • Dopln\u011bn\u00ed stravy pro vegany a vegetari\u00e1ny<\/strong><\/li>\n
    • Po bariatrick\u00e9 operaci<\/strong> \u2014 sleeve, bypass, duoden\u00e1ln\u00ed switch<\/li>\n
    • Dlouhodob\u00e1 l\u00e9\u010dba metforminem<\/strong> \u2014 vede k vy\u010derp\u00e1n\u00ed B12 u 30 % u\u017eivatel\u016f b\u011bhem 5\u201310 let<\/li>\n
    • Dlouhodob\u00e9 u\u017e\u00edv\u00e1n\u00ed PPI nebo H2 blok\u00e1tor\u016f<\/strong> \u2014 sni\u017euje vst\u0159eb\u00e1v\u00e1n\u00ed B12<\/li>\n
    • Atrofick\u00e1 gastritida u star\u0161\u00edch dosp\u011bl\u00fdch<\/strong><\/li>\n
    • Perifern\u00ed neuropatie s prok\u00e1zan\u00fdm nedostatkem B12<\/strong><\/li>\n
    • Afty a glositida zp\u016fsoben\u00e9 nedostatkem B12<\/strong><\/li>\n
    • Pre- a postnat\u00e1ln\u00ed suplementace<\/strong> u veganek (pod l\u00e9ka\u0159sk\u00fdm dohledem)<\/li>\n<\/ul>\n

      D\u00e1vkov\u00e1n\u00ed a pod\u00e1n\u00ed<\/h2>\n\n\n\n\n\n\n\n\n\n
      Pou\u017eit\u00ed<\/th>\nD\u00e1vka<\/th>\nD\u00e9lka<\/th>\n<\/tr>\n<\/thead>\n
      M\u00edrn\u00fd a\u017e st\u0159edn\u00ed nedostatek B12<\/td>\n1500 mcg jednou denn\u011b<\/td>\n3\u20136 m\u011bs\u00edc\u016f, pot\u00e9 udr\u017eovac\u00ed l\u00e9\u010dba<\/td>\n<\/tr>\n
      Udr\u017eovac\u00ed l\u00e9\u010dba po parenter\u00e1ln\u00edm nasycen\u00ed<\/td>\n1500 mcg jednou denn\u011b<\/td>\nDlouhodob\u00e1\/do\u017eivotn\u00ed (pernici\u00f3zn\u00ed an\u00e9mie)<\/td>\n<\/tr>\n
      Vegansk\u00e1 suplementace<\/td>\n1500 mcg jednou denn\u011b nebo 2 tablety dvakr\u00e1t t\u00fddn\u011b<\/td>\nProb\u00edh\u00e1<\/td>\n<\/tr>\n
      Dlouhodob\u00ed u\u017eivatel\u00e9 metforminu\/PPI<\/td>\n1500 mcg denn\u011b nebo obden<\/td>\nPokra\u010dovat po dobu u\u017e\u00edv\u00e1n\u00ed l\u00e9ku<\/td>\n<\/tr>\n
      T\u011b\u017ek\u00fd symptomatick\u00fd deficit s neurologick\u00fdmi projevy<\/td>\nNejprve aplikujte injekci (Neurobion nebo B12 IM); pro udr\u017eovac\u00ed l\u00e9\u010dbu p\u0159ejd\u011bte na tabletu 1500 mcg<\/td>\nDo\u017eivotn\u011b, pokud p\u0159etrv\u00e1v\u00e1 p\u0159\u00ed\u010dina<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

      Jak u\u017e\u00edvat:<\/strong> Zapijte sklenic\u00ed vody. Potrava v\u00fdznamn\u011b neovliv\u0148uje vst\u0159eb\u00e1v\u00e1n\u00ed vysokod\u00e1vkovan\u00e9 tablety \u2014 1% pod\u00edl pasivn\u00ed difuze je obecn\u011b stabiln\u00ed. U\u017e\u00edvejte ve stejnou denn\u00ed dobu pro udr\u017een\u00ed n\u00e1vyku.<\/p>\n

      Kdy zvolit injekce m\u00edsto tablet<\/strong> T\u011b\u017ek\u00fd symptomatick\u00fd deficit s prok\u00e1zan\u00fdm neurologick\u00fdm posti\u017een\u00edm (necitlivost, ataxie, kognitivn\u00ed p\u0159\u00edznaky) obvykle vy\u017eaduje nejprve parenter\u00e1ln\u00ed saturaci pro zaji\u0161t\u011bn\u00ed rychl\u00e9 n\u00e1hrady. Po stabilizaci p\u0159\u00edznak\u016f je p\u0159echod na vysokod\u00e1vkovou peror\u00e1ln\u00ed udr\u017eovac\u00ed l\u00e9\u010dbu B12 vhodn\u00fd pro v\u011bt\u0161inu pacient\u016f \u2014 v\u010detn\u011b v\u011bt\u0161iny pacient\u016f s pernici\u00f3zn\u00ed an\u00e9mi\u00ed.<\/div>\n

      B\u011b\u017en\u00e9 ne\u017e\u00e1douc\u00ed \u00fa\u010dinky<\/h2>\n

      Vitamin B12 je v\u00fdjime\u010dn\u011b dob\u0159e sn\u00e1\u0161en. P\u0159ebyte\u010dn\u00e9 B12 se vylu\u010duje mo\u010d\u00ed \u2014 neexistuje definovan\u00e1 horn\u00ed hranice bezpe\u010dn\u00e9ho p\u0159\u00edjmu. Hl\u00e1\u0161en\u00e9 \u00fa\u010dinky jsou neobvykl\u00e9 a obvykle m\u00edrn\u00e9:<\/p>\n