{"id":61394,"date":"2024-02-28T07:38:54","date_gmt":"2024-02-28T07:38:54","guid":{"rendered":"https:\/\/medsname.com\/epiduo-gel\/"},"modified":"2026-05-01T10:49:16","modified_gmt":"2026-05-01T10:49:16","slug":"epiduo-gel","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/epiduo-gel\/","title":{"rendered":"Epiduo gel"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Epiduo Gel?<\/h3>\n<p style=\"margin:0;\"><strong>Epiduo gel<\/strong> is a topical fixed-dose combination gel from Galderma containing <strong>adapalene 0.1% + benzoyl peroxide 2.5%<\/strong> &mdash; the gold-standard fixed-dose combination for moderate acne, combining a third-generation topical retinoid with the broad-spectrum antibacterial benzoyl peroxide. Apply a <strong>tenk\u00e1 vrstva aplikovan\u00e1 jednou denn\u011b ve\u010der<\/strong> k \u010di\u0161t\u011bn\u00ed such\u00e9 poko\u017eky. Budujte toleranci po dobu 2\u20134 t\u00fddn\u016f. Kombinujte s denn\u00edm SPF 30+. Viditeln\u00e9 zlep\u0161en\u00ed za <strong>4\u20138 t\u00fddn\u016f<\/strong>; maxim\u00e1ln\u00ed \u00fa\u010dinek za 12 t\u00fddn\u016f. Nevhodn\u00e9 pro t\u011bhotenstv\u00ed nebo t\u011b\u017ekou nodulocystickou akn\u00e9 (pou\u017eijte <a href=\"https:\/\/medsbase.com\/cs\/isotroin\/\">or\u00e1ln\u00ed isotretinoin<\/a> m\u00edsto toho).<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Co z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n<h2 class=\"wp-block-heading\">What Is Epiduo Gel?<\/h2>\n<p>Epiduo Gel is a topical combination gel from Galderma containing <strong>adapalene 0.1% + benzoyl peroxide 2.5%<\/strong>. the gold-standard fixed-dose combination for moderate acne, combining a third-generation topical retinoid with the broad-spectrum antibacterial benzoyl peroxide. The fixed-dose format means you get all the active ingredients in a single bedtime application instead of layering 2&ndash;3 separate products &mdash; significantly improving real-world adherence and reducing the chance of irritation from over-application.<\/p>\n<h2 class=\"wp-block-heading\">How Does Epiduo Gel Work?<\/h2>\n<p>Epiduo Gel targets multiple acne drivers simultaneously:<\/p>\n<ul>\n<li><strong>Adapalen<\/strong> &mdash; a third-generation retinoid that binds RAR-&beta; and RAR-&gamma; receptors. Comedolytic, anti-inflammatory, and significantly less irritating than tretinoin.<\/li>\n<li><strong>Benzoylperoxid (BPO)<\/strong> &mdash; oxidative antibacterial that kills <em>C. acnes<\/em> on contact. Unlike topical antibiotics, BPO does not produce bacterial resistance.<\/li>\n<li><strong>Kombinovan\u00fd \u00fa\u010dinek<\/strong> &mdash; targets all three drivers of inflammatory acne: comedone formation (adapalene), bacterial inflammation (BPO), and keratin plugging (both).<\/li>\n<\/ul>\n<p>Kombinovan\u00e1 terapie prokazuje v p\u0159\u00edm\u00fdch srovn\u00e1vac\u00edch studi\u00edch vy\u0161\u0161\u00ed \u00fa\u010dinnost ne\u017e monoterapie kteroukoli jednotlivou slo\u017ekou, p\u0159i srovnateln\u00e9 m\u00ed\u0159e podr\u00e1\u017ed\u011bn\u00ed.<\/p>\n<h2 class=\"wp-block-heading\">Pou\u017eit\u00ed a indikace<\/h2>\n<ul>\n<li><strong>Mild to moderate acne vulgaris<\/strong> &mdash; especially mixed comedonal + inflammatory acne<\/li>\n<li><strong>First-line monotherapy<\/strong> for adolescent and adult acne (per AAD 2024 and EDF guidelines)<\/li>\n<li><strong>Maintenance after oral antibiotics or isotretinoin<\/strong> &mdash; prevents relapse<\/li>\n<li><strong>St\u0159edn\u011b t\u011b\u017ek\u00e9 akn\u00e9 na trupu<\/strong> (hrudn\u00edk, z\u00e1da, ramena)<\/li>\n<\/ul>\n<p>Epiduo Gel is <strong>ne<\/strong> ur\u010den pro t\u011b\u017ek\u00e9 nodulocystick\u00e9 akn\u00e9 (peror\u00e1ln\u00ed isotretinoin), r\u016f\u017eovku nebo ekzemat\u00f3zn\u00ed poko\u017eku. T\u011b\u017ek\u00e9 akn\u00e9 se zjizven\u00edm by m\u011blo b\u00fdt odesl\u00e1no k <a href=\"https:\/\/medsbase.com\/cs\/isotroin\/\">or\u00e1ln\u00ed isotretinoin<\/a>.<\/p>\n<h2 class=\"wp-block-heading\">Epiduo Gel Dosage and How to Apply<\/h2>\n<p>Epiduo Gel comes in 30 g tube tubes containing adapalene 0.1% + benzoyl peroxide 2.5%.<\/p>\n<h3 class=\"wp-block-heading\">How to Apply Epiduo Gel Properly<\/h3>\n<ol>\n<li><strong>Jemn\u011b omyjte<\/strong> jemn\u00fdm nepen\u00edc\u00edm \u010distic\u00edm prost\u0159edkem a pot\u00e9 poklepejte do sucha. <strong>Po\u010dkejte 20\u201330 minut<\/strong> a\u017e poko\u017eka zcela uschne.<\/li>\n<li><strong>Naneste mno\u017estv\u00ed o velikosti hr\u00e1\u0161ku<\/strong> na celou posti\u017eenou oblast \u2013 obvykle cel\u00fd obli\u010dej. V\u011bt\u0161\u00ed mno\u017estv\u00ed gelu neurychluje \u00fa\u010dinek.<\/li>\n<li><strong>Naneste tenkou vrstvu<\/strong> na \u010delo, ob\u011b tv\u00e1\u0159e, nos a bradu. Vyhn\u011bte se o\u010dn\u00edm v\u00ed\u010dk\u016fm, rt\u016fm, koutk\u016fm \u00fast a vnit\u0159ku nosu.<\/li>\n<li><strong>Jednou denn\u011b ve\u010der<\/strong> podle postupn\u00e9ho navy\u0161ov\u00e1n\u00ed: <strong>2\u20133 noci v t\u00fddnu<\/strong> po prvn\u00ed 2 t\u00fddny, pot\u00e9 <strong>obden<\/strong>, pot\u00e9 <strong>ka\u017ed\u00fd ve\u010der<\/strong>.<\/li>\n<li><strong>Voliteln\u00e1 sendvi\u010dov\u00e1 metoda<\/strong> for sensitive skin: moisturiser &rarr; wait 5 min &rarr; Epiduo Gel &rarr; wait 5 min &rarr; moisturiser.<\/li>\n<li><strong>Denn\u00ed pou\u017e\u00edv\u00e1n\u00ed SPF 30+ r\u00e1no je povinn\u00e9.<\/strong> Jak retinoid (adapalen), tak gelov\u00e1 b\u00e1ze zvy\u0161uj\u00ed citlivost na UV z\u00e1\u0159en\u00ed.<\/li>\n<li><strong>Umyjte si ruce<\/strong> po aplikaci.<\/li>\n<li><strong>Watch for fabric bleaching:<\/strong> use white pillowcases and white towels at night. BPO permanently bleaches dark fabric.<\/li>\n<li><strong>Bu\u010fte trp\u011bliv\u00ed.<\/strong> Viditeln\u00e9 zlep\u0161en\u00ed po 4\u20138 t\u00fddnech; vrchol \u00fa\u010dinku v 12. t\u00fddnu.<\/li>\n<\/ol>\n<h2 class=\"wp-block-heading\">Side Effects of Epiduo Gel<\/h2>\n<p><strong>B\u011b\u017en\u00e9 (nejhor\u0161\u00ed v prvn\u00edch 1\u20134 t\u00fddnech, pot\u00e9 ustupuj\u00ed):<\/strong><\/p>\n<ul>\n<li>Such\u00e1 k\u016f\u017ee, olupov\u00e1n\u00ed, m\u00edrn\u00e9 \u0161upinat\u011bn\u00ed<\/li>\n<li>P\u00e1len\u00ed nebo \u0161t\u00edp\u00e1n\u00ed p\u0159i aplikaci<\/li>\n<li>M\u00edrn\u00e9 zarudnut\u00ed<\/li>\n<li>Zv\u00fd\u0161en\u00e1 citlivost na slunce<\/li>\n<li>Po\u010d\u00e1te\u010dn\u00ed zhor\u0161en\u00ed akn\u00e9 nebo \u201cpro\u010di\u0161t\u011bn\u00ed\u201d v t\u00fddnech 2\u20136<\/li>\n<\/ul>\n<p><strong>M\u00e9n\u011b \u010dast\u00e9:<\/strong><\/p>\n<ul>\n<li>Kontaktn\u00ed dermatitida<\/li>\n<li>Ekz\u00e9mov\u00e1 reakce<\/li>\n<li>Do\u010dasn\u00e1 hyperpigmentace na k\u016f\u017ei Fitzpatrick III\u2013VI<\/li>\n<li>Severe peeling or eczema-like irritation if used too frequently<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Varov\u00e1n\u00ed a opat\u0159en\u00ed<\/h2>\n<ul>\n<li><strong>T\u011bhotenstv\u00ed a kojen\u00ed:<\/strong> FDA Pregnancy Category C (adapalene); BPO is Category C in pregnancy. <strong>Not recommended in pregnancy.<\/strong> Switch to topical clindamycin or azelaic acid.<\/li>\n<li><strong>Vystaven\u00ed slunci:<\/strong> zv\u00fd\u0161en\u00e1 citlivost na UV z\u00e1\u0159en\u00ed. Denn\u00ed \u0161irokospektr\u00e1ln\u00ed SPF 30+ je povinn\u00e9. Vyhn\u011bte se sol\u00e1ri\u00edm.<\/li>\n<li><strong>Ekz\u00e9m, t\u011b\u017ek\u00e1 r\u016f\u017eovka, po\u0161kozen\u00e1 k\u016f\u017ee:<\/strong> po\u010dkejte, a\u017e se k\u016f\u017ee pln\u011b zahoj\u00ed.<\/li>\n<li><strong>Depilace voskem, nit\u00ed, laserov\u00e9 odstran\u011bn\u00ed chloupk\u016f, chemick\u00e9 peelingy:<\/strong> stop Epiduo Gel for 7&ndash;10 days before any of these procedures.<\/li>\n<li><strong>Jin\u00e9 topick\u00e9 \u00fa\u010dinn\u00e9 l\u00e1tky:<\/strong> vyhn\u011bte se kombinaci s s\u00e9ry s vysok\u00fdm obsahem AHA\/BHA, toniky s alkoholem nebo jin\u00fdmi retinoidy.<\/li>\n<li><strong>Bleaching:<\/strong> BPO will <strong>permanently bleach fabrics<\/strong> &mdash; pillowcases, towels, dark clothing, hair. Apply at night to white pillowcases or after the morning routine has dried.<\/li>\n<li><strong>D\u011bti do 12 let:<\/strong> pouze pod odborn\u00fdm dohledem.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Contraindications &mdash; Who Should NOT Use Epiduo Gel<\/h2>\n<ul>\n<li>Known hypersensitivity to adapalene, benzoyl peroxide, or any component of the gel base<\/li>\n<li>T\u011bhotenstv\u00ed nebo pl\u00e1nov\u00e1n\u00ed t\u011bhotenstv\u00ed (kv\u016fli slo\u017ece adapalenu)<\/li>\n<li>Aktivn\u00ed ekz\u00e9m, t\u011b\u017ek\u00e1 r\u016f\u017eovka, po\u0161kozen\u00e1 nebo mokvaj\u00edc\u00ed dermatitida v oblasti o\u0161et\u0159en\u00ed<\/li>\n<li>Sou\u010dasn\u00e1 terapie peror\u00e1ln\u00edm isotretinoinem<\/li>\n<li>D\u011bti do 12 let<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Interakce s l\u00e9ky a p\u00e9\u010d\u00ed o ple\u0165<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Kombinujte s<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u00da\u010dinek<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Co d\u011blat<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u010cistic\u00ed p\u0159\u00edpravek s kyselinou salicylovou<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Kompatibiln\u00ed \u2014 dopl\u0148kov\u00e9 mechanismy<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Use SA wash morning; Epiduo Gel at night.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">S\u00e9rum s vysok\u00fdm obsahem AHA\/BHA<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Siln\u00e9 kumulativn\u00ed podr\u00e1\u017ed\u011bn\u00ed<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Vyhn\u011bte se denn\u00edmu vrstven\u00ed.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Vitamin C (kyselina L-askorbov\u00e1)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Kompatibiln\u00ed<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Vitamin C in morning, Epiduo Gel at night.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Niacinamid<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Vynikaj\u00edc\u00ed dopln\u011bk \u2014 sni\u017euje z\u00e1n\u011bt, podporuje bari\u00e9ru<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Niacinamide morning, Epiduo Gel at night.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Peror\u00e1ln\u00ed isotretinoin<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Redundantn\u00ed retinoidn\u00ed efekt \u2014 nen\u00ed aditivn\u00ed<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Stop Epiduo Gel during oral isotretinoin course.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Tretinoin nebo jin\u00e9 topick\u00e9 retinoidy<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Redundant with adapalene<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Use only one topical retinoid.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 class=\"wp-block-heading\">Pokyny k uchov\u00e1v\u00e1n\u00ed<\/h2>\n<ul>\n<li>Skladujte p\u0159i pokojov\u00e9 teplot\u011b, <strong>15\u201325\u00b0C<\/strong>. Neschov\u00e1vejte v lednici ani nezamrazujte.<\/li>\n<li>Uchov\u00e1vejte tubu pevn\u011b uzav\u0159enou.<\/li>\n<li>BPO is light-sensitive &mdash; keep tube in original carton, away from direct sunlight.<\/li>\n<li>Zlikvidujte 6 m\u011bs\u00edc\u016f po prvn\u00edm otev\u0159en\u00ed.<\/li>\n<li>Uchov\u00e1vejte mimo dosah d\u011bt\u00ed a dom\u00e1c\u00edch zv\u00ed\u0159at.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Souvisej\u00edc\u00ed alternativy na MedsBase<\/h2>\n<p>Dal\u0161\u00ed lok\u00e1ln\u00ed a peror\u00e1ln\u00ed l\u00e9\u010dba akn\u00e9 dostupn\u00e1 na MedsBase:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/deriva-cms-gel\/\"><strong>Deriva CMS gel (adapalen + klindamycin + hydrata\u010dn\u00ed slo\u017eka)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/clincitop-gel\/\"><strong>Clincitop Gel (klindamycin 1%)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/saslic-foaming-face-wash\/\"><strong>Saslic P\u011bna na obli\u010dej (kyselina salicylov\u00e1 2%)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/retino-a-cream\/\"><strong>Retino-A Kr\u00e9m (tretinoin 0,025% \/ 0,05%)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/retino-a-micro-gel\/\"><strong>Retino-A Micro Gel (tretinoin mikrosf\u00e9ry 0,04% \/ 0,1%)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/tretiheal-cream\/\"><strong>Tretiheal Kr\u00e9m (tretinoin 0,025% \/ 0,05% \/ 0,1%)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/tazret-forte-cream\/\"><strong>Tazret Forte Kr\u00e9m (tazaroten 0,1%)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/isotroin\/\"><strong>Isotroin (peror\u00e1ln\u00ed isotretinoin 5\/10\/20\/30 mg)<\/strong><\/a><\/li>\n<\/ul>\n<p>U\u017eite\u010dn\u00e9 \u010dten\u00ed: <a href=\"https:\/\/medsbase.com\/cs\/tretinoin-cream-vs-gel\/\">Tretinoin kr\u00e9m vs. gel<\/a> \u00b7 <a href=\"https:\/\/medsbase.com\/cs\/isotretinoin-vs-tretinoin\/\">Isotretinoin vs. tretinoin<\/a> \u00b7 <a href=\"https:\/\/medsbase.com\/cs\/everything-you-want-to-know-about-acne\/\">V\u0161e, co chcete v\u011bd\u011bt o akn\u00e9<\/a>.<\/p>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3 class=\"wp-block-heading\">Why is benzoyl peroxide important in Epiduo Gel?<\/h3>\n<p>Benzoyl peroxide kills <em>C. acnes<\/em> by oxidative damage that bacteria cannot develop resistance to &mdash; unlike clindamycin or erythromycin. It is the only acne ingredient that suppresses bacterial resistance development. The combination with adapalene means BPO blocks resistance even if you ever pair this with topical or oral antibiotics later.<\/p>\n<h3 class=\"wp-block-heading\">Kdy uvid\u00edm v\u00fdsledky?<\/h3>\n<p>Viditeln\u00e9 sn\u00ed\u017een\u00ed z\u00e1n\u011btliv\u00fdch pup\u00ednk\u016f po <strong>4\u20136 t\u00fddnech<\/strong>. Sn\u00ed\u017een\u00ed komedon\u016f po <strong>8\u201312 t\u00fddnech<\/strong>. Maxim\u00e1ln\u00ed \u00fa\u010dinek po <strong>12 t\u00fddnech<\/strong>. Prvn\u00edch 2\u20136 t\u00fddn\u016f m\u016f\u017ee zahrnovat do\u010dasn\u00e9 zhor\u0161en\u00ed akn\u00e9 \u2014 nep\u0159est\u00e1vejte. Skute\u010dn\u00e9 zlep\u0161en\u00ed p\u0159ich\u00e1z\u00ed po 4. t\u00fddnu.<\/p>\n<h3 class=\"wp-block-heading\">Je po\u010d\u00e1te\u010dn\u00ed vzplanut\u00ed akn\u00e9 norm\u00e1ln\u00ed?<\/h3>\n<p>Yes &mdash; about 30&ndash;50% of patients have a temporary worsening in weeks 2&ndash;6 as adapalene surfaces existing microcomedones. Drop frequency to every other night until the flare settles, then resume nightly. Stopping for the flare is the most common reason Epiduo Gel &ldquo;does not work&rdquo;.<\/p>\n<h3 class=\"wp-block-heading\">Is Epiduo Gel safe in pregnancy?<\/h3>\n<p>FDA Pregnancy Category C (adapalene); BPO is Category C in pregnancy. <strong>Not recommended in pregnancy.<\/strong> Switch to topical clindamycin or azelaic acid.<\/p>\n<h3 class=\"wp-block-heading\">Will Epiduo Gel bleach my pillowcase?<\/h3>\n<p>Yes &mdash; permanently. Benzoyl peroxide bleaches dark fabric, hair colour, and dyed towels on contact. Use white pillowcases at night and white towels for face-drying while on this product.<\/p>\n<h3 class=\"wp-block-heading\">Do I really need sunscreen with Epiduo Gel?<\/h3>\n<p>Ano \u2014 bez diskuse. Retinoidn\u00ed slo\u017eka zten\u010duje svrchn\u00ed vrstvu k\u016f\u017ee a sni\u017euje UV ochrann\u00e9 melaninov\u00e9 \u010depi\u010dky. Bez denn\u00edho \u0161irokospektr\u00e1ln\u00edho SPF 30+ o\u010dek\u00e1vejte sp\u00e1len\u00ed, hyperpigmentaci a p\u0159ed\u010dasn\u00e9 st\u00e1rnut\u00ed \u2014 p\u0159esn\u00fd opak toho, \u010deho jste cht\u011bli dos\u00e1hnout l\u00e9\u010dbou akn\u00e9.<\/p>\n<h3 class=\"wp-block-heading\">Can I wax, get laser hair removal, or have a chemical peel while on Epiduo Gel?<\/h3>\n<p>Ne \u2014 p\u0159eru\u0161te l\u00e9\u010dbu alespo\u0148 7\u201310 dn\u00ed p\u0159ed jakoukoli depilac\u00ed voskem, nit\u00ed, laserem, dermabraz\u00ed, mikroneedlingem nebo chemick\u00fdm peelingem. Pokra\u010dujte a\u017e po \u00fapln\u00e9m zhojen\u00ed k\u016f\u017ee (dal\u0161\u00edch 5\u20137 dn\u00ed).<\/p>\n<h3 class=\"wp-block-heading\">Epiduo Gel vs oral isotretinoin &mdash; which is right for me?<\/h3>\n<p>Epiduo Gel is for <strong>m\u00edrn\u00e9 a\u017e st\u0159edn\u011b z\u00e1va\u017en\u00e9 akn\u00e9<\/strong>. <a href=\"https:\/\/medsbase.com\/cs\/isotroin\/\">Peror\u00e1ln\u00ed isotretinoin (Isotroin)<\/a> je ur\u010den pro <strong>t\u011b\u017ek\u00e1 nodulocystick\u00e1 akn\u00e9<\/strong>, scarring acne, or acne that has failed 6+ months of optimised topical therapy. Epiduo Gel will not clear severe cystic acne &mdash; do not waste 12 weeks finding out.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Souvisej\u00edc\u00ed alternativy<\/h3>\n<p>Dal\u0161\u00ed produkty v <strong>L\u00e9\u010dba akn\u00e9<\/strong> kter\u00e9 z\u00e1kazn\u00edci tak\u00e9 prohl\u00ed\u017eej\u00ed:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/tretiva\/\">Tretiva<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/tazret-forte-cream\/\">Tazret Forte kr\u00e9m<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/yaz\/\">Yaz<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/melacare-forte-cream\/\">Melacare Forte kr\u00e9m<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/tretizen\/\">Tretizen<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Odstra\u0148uje akn\u00e9<br \/>\n\u2705 Sni\u017euje z\u00e1n\u011bt<br \/>\n\u2705 Prevents new breakouts<br \/>\n\u2705 Zlep\u0161uje texturu poko\u017eky<br \/>\n\u2705 Minimizes pore size<\/p>\n<p>Epiduo Gel contains Adapalene and Benzoyl Peroxide.<\/p>","protected":false},"featured_media":61395,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[3215,3642,3141,3223,3342],"product_tag":[3644,5024,5025],"class_list":{"0":"post-61394","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-acne-treatment","7":"product_cat-beauty-skin-care","8":"product_cat-category-overview","9":"product_cat-chronic-conditions","10":"product_cat-general-health","11":"product_tag-adapalene","12":"product_tag-benzoyl-peroxide","13":"product_tag-epiduo-gel","15":"first","16":"instock","17":"shipping-taxable","18":"purchasable","19":"product-type-variable","20":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/61394","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=61394"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/61395"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=61394"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=61394"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=61394"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=61394"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}