{"id":61596,"date":"2024-03-03T06:01:14","date_gmt":"2024-03-03T06:01:14","guid":{"rendered":"https:\/\/medsname.com\/bicalumutide\/"},"modified":"2026-04-30T10:23:34","modified_gmt":"2026-04-30T10:23:34","slug":"bicalumutide","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/bicalumutide\/","title":{"rendered":"Bicalumutide"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Bicalumutide?<\/h3>\n<p style=\"margin:0;\"><strong>Bicalumutide<\/strong> je peror\u00e1ln\u00ed tableta od spole\u010dnosti Cipla obsahuj\u00edc\u00ed <strong>bicalutamide 50 mg<\/strong> \u2014 nesteroidn\u00ed <strong>antagonista androgenn\u00edho receptoru (antiandrogen)<\/strong> pou\u017e\u00edv\u00e1 se k <strong>pokro\u010dil\u00fd nebo metastatick\u00fd karcinom prostaty<\/strong>. Standardn\u00ed role: v kombinaci s <strong>agonistou LHRH<\/strong> (goserelin, leuprorelin) pro kombinovanou androgenn\u00ed blok\u00e1du (CAB). Standardn\u00ed d\u00e1vkov\u00e1n\u00ed: <strong>50 mg once daily (with LHRH agonist) or 150 mg once daily (monotherapy)<\/strong>. Main side effects: gynaecomastia and breast tenderness (common), hot flushes, hepatotoxicity (mandatory LFT monitoring), reduced libido, rare interstitial pneumonitis. <strong>Povinn\u00e9: vstupn\u00ed + m\u011bs\u00ed\u010dn\u00ed jatern\u00ed testy po prvn\u00ed 4 m\u011bs\u00edce, pot\u00e9 periodicky.<\/strong><\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Co z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:0 0 24px 0;border-radius:4px;font-size:14px;\"><strong>\u26a0 Vy\u017eaduje se odborn\u00fd dohled.<\/strong> L\u00e9ky na rakovinu mus\u00ed b\u00fdt p\u0159edeps\u00e1ny o\u0161et\u0159uj\u00edc\u00edm onkologem s potvrzenou diagn\u00f3zou, vstupn\u00edm stagingem a definovan\u00fdm l\u00e9\u010debn\u00fdm pl\u00e1nem. Nikdy neza\u010d\u00ednejte, nep\u0159eru\u0161ujte, nem\u011b\u0148te d\u00e1vkov\u00e1n\u00ed ani neu\u017e\u00edvejte l\u00e9ky na rakovinu mimo onkologick\u00fd l\u00e9\u010debn\u00fd pl\u00e1n. V\u011bt\u0161ina l\u00e9k\u016f na rakovinu vy\u017eaduje pravideln\u00e9 monitorov\u00e1n\u00ed krevn\u00edch test\u016f (krevn\u00ed obraz, jatern\u00ed testy, funkce ledvin), je absolutn\u011b kontraindikov\u00e1na v t\u011bhotenstv\u00ed a m\u00e1 v\u00fdznamn\u00e9 l\u00e9kov\u00e9 interakce.<\/div>\n<h2 class=\"wp-block-heading\">What Is Bicalumutide?<\/h2>\n<p>Bicalumutide is an oral tablet from Cipla containing <strong>bicalutamide 50 mg<\/strong>. Bicalutamide is a non-steroidal anti-androgen that competitively blocks the androgen receptor in prostate cancer cells, inhibiting the proliferative effect of testosterone and dihydrotestosterone (DHT). It is used in <strong>pokro\u010dil\u00fd nebo metastatick\u00fd karcinom prostaty<\/strong>, t\u00e9m\u011b\u0159 v\u017edy v kombinaci s agonistou LHRH (goserelin, leuprorelin, triptorelin) pro <strong>kombinovanou androgenn\u00ed blok\u00e1du (CAB)<\/strong>.<\/p>\n<h2 class=\"wp-block-heading\">How Does Bicalumutide Work?<\/h2>\n<p>Prostate cancer growth is driven by androgen-receptor signalling. Standard androgen deprivation therapy (ADT) suppresses ovarian androgen production through LHRH agonists. However, the adrenal glands continue to produce ~10% of total body androgens, and the residual signal is enough to drive disease progression in many patients. Bicalumutide blocks the androgen receptor itself, so the residual adrenal androgens cannot signal &mdash; producing more complete androgen blockade.<\/p>\n<ul>\n<li><strong>Kompetitivn\u00ed antagonista androgenn\u00edho receptoru<\/strong> \u2014 v\u00e1\u017ee se na AR a br\u00e1n\u00ed testosteronu \/ DHT v jeho aktivaci.<\/li>\n<li><strong>Long half-life (~6 days)<\/strong> &mdash; once-daily oral dosing.<\/li>\n<li><strong>Pou\u017e\u00edv\u00e1 se k prevenci \u201cn\u00e1dorov\u00e9ho vzplanut\u00ed\u201d<\/strong> p\u0159i zah\u00e1jen\u00ed terapie agonistou LHRH \u2013 po\u010d\u00e1te\u010dn\u00ed vzestup testosteronu indukovan\u00fd LHRH m\u016f\u017ee do\u010dasn\u011b zhor\u0161it onemocn\u011bn\u00ed, a p\u0159edl\u00e9\u010dba antiandrogenem tomu zabr\u00e1n\u00ed.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Pou\u017eit\u00ed a indikace<\/h2>\n<ul>\n<li><strong>Kombinovan\u00e1 blok\u00e1da androgen\u016f (CAB)<\/strong> u pokro\u010dil\u00e9 nebo metastatick\u00e9 rakoviny prostaty (s agonistou LHRH)<\/li>\n<li><strong>Prevence n\u00e1dorov\u00e9ho vzplanut\u00ed<\/strong> p\u0159i zah\u00e1jen\u00ed terapie agonistou LHRH (2\u20134 t\u00fddny p\u0159ed l\u00e9\u010dbou)<\/li>\n<li><strong>Monotherapy 150 mg\/day<\/strong> in locally advanced non-metastatic prostate cancer (alternative to LHRH agonist for patients prioritising sexual function preservation)<\/li>\n<li><strong>Po biochemick\u00e9 recidiv\u011b<\/strong> jako sou\u010d\u00e1st p\u0159eru\u0161ovan\u00fdch nebo kontinu\u00e1ln\u00edch re\u017eim\u016f deprivace androgen\u016f<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Bicalumutide Dosage and How to Take<\/h2>\n<p>Standardn\u00ed d\u00e1vka: <strong>50 mg once daily (with LHRH agonist) or 150 mg once daily (monotherapy)<\/strong>.<\/p>\n<ol>\n<li><strong>Jednou denn\u011b ve stejnou dobu ka\u017ed\u00fd den.<\/strong> S j\u00eddlem nebo bez j\u00eddla.<\/li>\n<li><strong>Polykejte cel\u00e9 s vodou.<\/strong><\/li>\n<li><strong>Povinn\u00e9 monitorov\u00e1n\u00ed:<\/strong> vstupn\u00ed jatern\u00ed testy (AST, ALT) a PSA. Opakujte jatern\u00ed testy <strong>m\u011bs\u00ed\u010dn\u011b po prvn\u00ed 4 m\u011bs\u00edce<\/strong>, pot\u00e9 ka\u017ed\u00e9 3\u20136 m\u011bs\u00edc\u016f. PSA ka\u017ed\u00e9 3 m\u011bs\u00edce. P\u0159eru\u0161te l\u00e9\u010dbu a vy\u0161et\u0159ete, pokud AST\/ALT &gt; 3\u00d7 horn\u00ed hranice normy.<\/li>\n<li><strong>Prevence n\u00e1dorov\u00e9ho vzplanut\u00ed p\u0159ed LHRH agonistou:<\/strong> start Bicalumutide 2&ndash;4 weeks before LHRH agonist initiation, continue for at least 1 month after.<\/li>\n<li><strong>Nep\u0159eru\u0161ujte l\u00e9\u010dbu bez pokyn\u016f onkologa.<\/strong><\/li>\n<\/ol>\n<h2 class=\"wp-block-heading\">Side Effects of Bicalumutide<\/h2>\n<p><strong>\u010cast\u00e9:<\/strong><\/p>\n<ul>\n<li>Gynekomastie a citlivost prs\u016f (40\u201370% u monoterapie; m\u00e9n\u011b u CAB)<\/li>\n<li>N\u00e1valy horka<\/li>\n<li>Sn\u00ed\u017een\u00e9 libido a erektiln\u00ed dysfunkce<\/li>\n<li>\u00danava, astenie<\/li>\n<li>Pr\u016fjem (zejm\u00e9na u flutamidu)<\/li>\n<li>M\u00edrn\u00e9 za\u017e\u00edvac\u00ed pot\u00ed\u017ee<\/li>\n<\/ul>\n<p><strong>D\u016fle\u017eit\u00e9 \u2013 povinn\u00e9 monitorov\u00e1n\u00ed:<\/strong><\/p>\n<ul>\n<li><strong>Hepatotoxicita<\/strong> \u2014 m\u016f\u017ee b\u00fdt z\u00e1va\u017en\u00e1 a nep\u0159edv\u00eddateln\u00e1. Okam\u017eit\u011b p\u0159eru\u0161te l\u00e9\u010dbu p\u0159i \u017eloutence, tmav\u00e9 mo\u010di, siln\u00e9 \u00fanav\u011b nebo hodnot\u00e1ch AST\/ALT &gt; 3\u00d7 ULN. V\u011bt\u0161ina p\u0159\u00edpad\u016f se objev\u00ed b\u011bhem prvn\u00edch 4 m\u011bs\u00edc\u016f.<\/li>\n<li>Rare interstitial pneumonitis &mdash; new-onset cough, dyspnoea<\/li>\n<\/ul>\n<p><strong>Vz\u00e1cn\u00e9:<\/strong> hemolytick\u00e1 an\u00e9mie, fotosenzitivita, z\u00e1va\u017en\u00e9 ko\u017en\u00ed reakce.<\/p>\n<h2 class=\"wp-block-heading\">Varov\u00e1n\u00ed a opat\u0159en\u00ed<\/h2>\n<ul>\n<li><strong>T\u011bhotenstv\u00ed a kojen\u00ed:<\/strong> nepou\u017eiteln\u00e9 (indikace pouze pro mu\u017ee), ale antiandrogeny jsou fetotoxick\u00e9, pokud jsou omylem u\u017e\u00edv\u00e1ny b\u011bhem t\u011bhotenstv\u00ed.<\/li>\n<li><strong>Funkce jater:<\/strong> povinn\u00e9 m\u011bs\u00ed\u010dn\u00ed testy jatern\u00edch funkc\u00ed po prvn\u00ed 4 m\u011bs\u00edce. P\u0159eru\u0161te p\u0159i hodnot\u00e1ch AST\/ALT &gt; 3\u00d7 ULN.<\/li>\n<li><strong>Diabetes:<\/strong> m\u016f\u017ee zhor\u0161it glykemickou kontrolu.<\/li>\n<li><strong>Kardiovaskul\u00e1rn\u00ed:<\/strong> ADT obecn\u011b je spojeno se zv\u00fd\u0161en\u00fdm v\u00fdskytem kardiovaskul\u00e1rn\u00edch p\u0159\u00edhod. Optimalizujte modifikovateln\u00e9 rizikov\u00e9 faktory.<\/li>\n<li><strong>Profylaxe gynekomastie:<\/strong> n\u00edzkod\u00e1vkovan\u00fd tamoxifen 10\u201320 mg\/den nebo profylaktick\u00e1 radioterapie prsu sni\u017euje incidenci (specialista).<\/li>\n<li><strong>\u0158\u00edzen\u00ed vozidla:<\/strong> opatrnost \u2014 \u00fanava a z\u00e1vrat\u011b mohou ovlivnit schopnost \u0159\u00eddit.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Interakce s l\u00e9\u010divy<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;\">Kombinujte s<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;\">\u00da\u010dinek<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;\">Co d\u011blat<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Warfarin a dal\u0161\u00ed kumarinov\u00e9 antikoagulancia<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">V\u00fdznamn\u00e9 zv\u00fd\u0161en\u00ed INR \u2014 riziko krv\u00e1cen\u00ed<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Kontrolujte INR t\u00fddn\u011b zpo\u010d\u00e1tku. Sni\u017ete d\u00e1vku warfarinu o 30\u201350 %.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">CYP3A4 inhibitors (minor effect)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Raise bicalutamide levels<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Monitorujte hepatotoxicitu.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Analoga LHRH (goserelin, leuprorelin)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Standardn\u00ed kombinace \u2014 kombinovan\u00e1 androgenn\u00ed blok\u00e1da<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Standardn\u00ed re\u017eim CAB.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Alkohol<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Aditivn\u00ed hepatotoxicita<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Omezte p\u0159\u00edjem alkoholu b\u011bhem l\u00e9\u010dby.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 class=\"wp-block-heading\">Skladov\u00e1n\u00ed<\/h2>\n<ul>\n<li>Skladujte p\u0159i pokojov\u00e9 teplot\u011b, 15\u201325 \u00b0C, v p\u016fvodn\u00edm blistru.<\/li>\n<li>Uchov\u00e1vejte mimo dosah d\u011bt\u00ed, \u017een a dom\u00e1c\u00edch zv\u00ed\u0159at \u2014 antiandrogeny jsou fetotoxick\u00e9.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Souvisej\u00edc\u00ed alternativy na MedsBase<\/h2>\n<p>Dal\u0161\u00ed onkologick\u00e9 l\u00e9ky skladem vedle tohoto produktu:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/bdenza\/\"><strong>Bdenza (enzalutamid 40 mg)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/cytomid\/\"><strong>Cytomid (flutamide 250 mg)<\/strong><\/a><\/li>\n<\/ul>\n<p><a href=\"https:\/\/medsbase.com\/cs\/anti-cancer-medication\/\">Prohl\u00e9dn\u011bte v\u0161echny protin\u00e1dorov\u00e9 l\u00e9ky \u2192<\/a><\/p>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3 class=\"wp-block-heading\">Why is Bicalumutide usually combined with an LHRH agonist?<\/h3>\n<p>LHRH agonists (goserelin, leuprorelin) suppress testicular androgen production, but the adrenal glands continue producing ~10% of body androgens that can drive prostate cancer growth. Bicalumutide blocks the androgen receptor itself, so adrenal androgens cannot signal. The combination is called <strong>kombinovanou androgenn\u00ed blok\u00e1du (CAB)<\/strong> a poskytuje hlub\u0161\u00ed potla\u010den\u00ed androgen\u016f ne\u017e samotn\u00fd agonista LHRH u pokro\u010dil\u00e9ho onemocn\u011bn\u00ed.<\/p>\n<h3 class=\"wp-block-heading\">What is &ldquo;tumour flare&rdquo; and why does Bicalumutide prevent it?<\/h3>\n<p>When LHRH agonist therapy starts, the pituitary is initially stimulated and testosterone surges for 1&ndash;2 weeks before downregulation kicks in. In patients with significant disease burden (bone metastases, urinary obstruction, spinal cord compression risk), this transient testosterone surge can worsen symptoms acutely. Starting Bicalumutide 2&ndash;4 weeks before the LHRH agonist blocks the receptor and prevents the flare.<\/p>\n<h3 class=\"wp-block-heading\">Jak se \u0159e\u0161\u00ed gynekomastie?<\/h3>\n<p>Citlivost prsou a gynekomastie postihuje 40\u201370 % pacient\u016f na monoterapii bikalutamidem ve vy\u0161\u0161\u00edch d\u00e1vk\u00e1ch. Mo\u017enosti profylaxe: <strong>n\u00edzk\u00e1 d\u00e1vka tamoxifenu 10\u201320 mg\/den<\/strong> (nejv\u00edce d\u016fkaz\u016f) nebo <strong>profylaktick\u00e9 oza\u0159ov\u00e1n\u00ed prsou<\/strong> jako jednor\u00e1zov\u00e1 frakce 8\u201312 Gy p\u0159ed zah\u00e1jen\u00edm antiandrogenn\u00ed terapie. P\u0159ed zah\u00e1jen\u00edm l\u00e9\u010dby proberte s onkologem, pokud jsou kosmetick\u00e9 obavy v\u00fdznamn\u00e9.<\/p>\n<h3 class=\"wp-block-heading\">Jak\u00e9 krevn\u00ed testy pot\u0159ebuji?<\/h3>\n<p><strong>Povinn\u00e9:<\/strong> z\u00e1kladn\u00ed jatern\u00ed testy (AST, ALT) a PSA. Pot\u00e9 jatern\u00ed testy <strong>m\u011bs\u00ed\u010dn\u011b po prvn\u00ed 4 m\u011bs\u00edce<\/strong>, then every 3&ndash;6 months. PSA every 3 months. Stop Bicalumutide immediately and contact your oncologist if AST\/ALT &gt; 3&times; ULN, or for any jaundice, dark urine or severe fatigue.<\/p>\n<h3 class=\"wp-block-heading\">Can I drink alcohol on Bicalumutide?<\/h3>\n<p>Limit alcohol &mdash; both alcohol and bicalutamide are hepatotoxic and the combination amplifies the risk of severe drug-induced liver injury. Occasional small amounts are usually tolerable; heavy or daily drinking should be avoided throughout treatment.<\/p>\n<h3 class=\"wp-block-heading\">Bicalumutide vs flutamide vs enzalutamide &mdash; what is the difference?<\/h3>\n<p>All three are oral anti-androgens for prostate cancer. <strong>Bicalutamide:<\/strong> once-daily, well-tolerated, standard first-generation choice. <strong>Flutamide:<\/strong> three-times-daily, more diarrhoea and hepatotoxicity risk &mdash; largely replaced by bicalutamide. <strong>Enzalutamide:<\/strong> second-generation, more potent, used for castration-resistant disease (after CAB has failed) &mdash; see <a href=\"https:\/\/medsbase.com\/cs\/bdenza\/\">Bdenza<\/a>.<\/p>\n<h3 class=\"wp-block-heading\">Will Bicalumutide affect my heart?<\/h3>\n<p>Monoterapie antiandrogeny m\u00e1 minim\u00e1ln\u00ed p\u0159\u00edm\u00fd kardiovaskul\u00e1rn\u00ed \u00fa\u010dinek, ale \u0161ir\u0161\u00ed androgenn\u00ed depriva\u010dn\u00ed terapie (LHRH agonista + antiandrogen) je spojena se zv\u00fd\u0161en\u00fdm v\u00fdskytem kardiovaskul\u00e1rn\u00edch p\u0159\u00edhod v\u010detn\u011b infarktu myokardu a c\u00e9vn\u00ed mozkov\u00e9 p\u0159\u00edhody. Optimalizujte kardiovaskul\u00e1rn\u00ed rizikov\u00e9 faktory: kontrolu krevn\u00edho tlaku, u\u017e\u00edv\u00e1n\u00ed statin\u016f p\u0159i hyperlipidemii, odvyk\u00e1n\u00ed kou\u0159en\u00ed, cvi\u010den\u00ed a spr\u00e1vnou hmotnost.<\/p>\n<h3 class=\"wp-block-heading\">Can I stop Bicalumutide if PSA stays low?<\/h3>\n<p>Proberte se sv\u00fdm onkologem. U n\u011bkter\u00fdch p\u0159eru\u0161ovan\u00fdch protokol\u016f CAB se CAB p\u0159eru\u0161\u00ed, kdy\u017e je PSA potla\u010deno pod prahovou hodnotu, a obnov\u00ed se p\u0159i vzestupu PSA \u2014 to m\u016f\u017ee sn\u00ed\u017eit vedlej\u0161\u00ed \u00fa\u010dinky bez kompromitace p\u0159e\u017eit\u00ed. Nikdy nep\u0159eru\u0161ujte jednostrann\u011b \u2014 monitorov\u00e1n\u00ed PSA a na\u010dasov\u00e1n\u00ed obnoven\u00ed jsou kl\u00ed\u010dov\u00e9.<\/p>\n<div style=\"background:#f4f8fb;border:1px solid #d6e4ec;padding:12px 18px;margin:14px 0;border-radius:4px;font-size:14px;color:#3a5160;text-align:center;\">\n<strong>\ud83d\udd12 \u0160ifrovan\u00e9 platby<\/strong> \u00b7 <strong>\ud83d\udcb3 Ov\u011b\u0159en\u00fd platebn\u00ed procesor<\/strong> \u00b7 <strong>\ud83d\ude9a Doprava do cel\u00e9ho sv\u011bta<\/strong> \u00b7 <strong>\u2b50 4,9\/5 od 1 400+ z\u00e1kazn\u00edk\u016f<\/strong>\n<\/div>\n<p><!-- medsbase-why-order --><\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Ka\u017ed\u00e1 \u0161ar\u017ee je dod\u00e1v\u00e1na od <strong>v\u00fdrobce certifikovan\u00e9ho WHO-GMP<\/strong>. Objedn\u00e1vky jsou expedov\u00e1ny v nen\u00e1padn\u00fdch obalech bez loga od na\u0161ich partnersk\u00fdch sklad\u016f a jsou pokryty na\u0161\u00ed <a href=\"\/cs\/medsbase-re-shipment-assurance-policy\/\">Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/a>: pokud z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, za\u0161leme zdarma n\u00e1hradn\u00ed z\u00e1silku, bez dotaz\u016f.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Souvisej\u00edc\u00ed alternativy<\/h3>\n<p>Dal\u0161\u00ed produkty v <strong>Chronick\u00e1 onemocn\u011bn\u00ed<\/strong> kter\u00e9 z\u00e1kazn\u00edci tak\u00e9 prohl\u00ed\u017eej\u00ed:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/riborea\/\">Riborea<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/bacloheal\/\">Bacloheal<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/amlode\/\">Amlode<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/nicerbium\/\">Nicerbium<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/lipril-h\/\">Lipril-H<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 L\u00e9\u010d\u00ed rakovinu prostaty<br \/>\n\u2705 Blocks male hormones<br \/>\n\u2705 Slows tumor growth<br \/>\n\u2705 Zlep\u0161uje m\u00edru p\u0159e\u017eit\u00ed<br \/>\n\u2705 Reduces cancer symptoms<\/p>\n<p>Bicalumutide contains Bicalutamide.<\/p>","protected":false},"featured_media":61597,"comment_status":"closed","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3595,3614,3141,3223,3342],"product_tag":[5066,5067],"class_list":{"0":"post-61596","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-cancer-medication","7":"product_cat-bladder-prostate","8":"product_cat-category-overview","9":"product_cat-chronic-conditions","10":"product_cat-general-health","11":"product_tag-bicalumutide","12":"product_tag-bicalutamide","14":"first","15":"instock","16":"shipping-taxable","17":"purchasable","18":"product-type-variable","19":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/61596","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=61596"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/61597"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=61596"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=61596"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=61596"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=61596"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}