{"id":61622,"date":"2024-03-03T08:29:33","date_gmt":"2024-03-03T08:29:33","guid":{"rendered":"https:\/\/medsname.com\/nucoxia-sp\/"},"modified":"2026-05-10T08:48:12","modified_gmt":"2026-05-10T08:48:12","slug":"nucoxia-sp","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/nucoxia-sp\/","title":{"rendered":"Nucoxia SP"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Nucoxia SP?<\/h3>\n<p style=\"margin:0;\"><strong>Nucoxia SP<\/strong> je tableta s fixn\u00ed kombinac\u00ed <strong>etoricoxib 60&nbsp;mg + serratiopeptidase 10&nbsp;mg<\/strong>. It pairs a highly selective COX-2 NSAID (etoricoxib) with a proteolytic enzyme (serratiopeptidase) to give <strong>combined anti-inflammatory and anti-oedema (anti-swelling) action<\/strong>. Typical use is <strong>one tablet once daily with food<\/strong>, usually for short-term post-operative or post-traumatic pain with swelling, and for acute musculoskeletal pain where tissue oedema is prominent.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Co z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n<p><strong>Nucoxia SP<\/strong> is a combination tablet widely used across India for musculoskeletal pain with swelling. It combines:<\/p>\n<ul>\n<li><strong>Etoricoxib 60&nbsp;mg<\/strong> &mdash; a highly selective COX-2 inhibitor for pain and inflammation<\/li>\n<li><strong>Serratiopeptidase 10&nbsp;mg<\/strong> &mdash; a proteolytic enzyme originally isolated from <em>Serratia marcescens<\/em>, used for its anti-oedema and fibrinolytic action<\/li>\n<\/ul>\n<p>The rationale for combining the two is that etoricoxib tackles prostaglandin-driven pain and inflammation while serratiopeptidase breaks down bradykinin and fibrin in oedematous tissue &mdash; the kind of swelling that builds up after an injury, after dental or soft-tissue surgery, or during an active joint flare. The two mechanisms are complementary rather than overlapping.<\/p>\n<h2 class=\"wp-block-heading\">What Is Nucoxia SP Used For?<\/h2>\n<ul>\n<li><strong>Post-operative soft-tissue inflammation and oedema<\/strong> &mdash; dental extractions, orthopaedic surgery, ENT procedures, gynaecological procedures<\/li>\n<li><strong>Acute musculoskeletal injuries with swelling<\/strong> &mdash; sprains, strains, ankle injury, contusions<\/li>\n<li><strong>Osteoarthritis and rheumatoid arthritis flares<\/strong> with marked joint swelling<\/li>\n<li><strong>Ankylosing spondylitis<\/strong> symptomatic management<\/li>\n<li><strong>Fibrocystick\u00e1 mastopatie<\/strong> (off-label; specialist advice)<\/li>\n<li><strong>Post-traumatic haematoma and localised oedema<\/strong><\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">How Does Nucoxia SP Work?<\/h2>\n<ul>\n<li><strong>Etoricoxib<\/strong> selectively inhibits COX-2, reducing inflammatory prostaglandin synthesis. This gives strong pain and inflammation control with less gastric-ulcer risk than non-selective NSAIDs.<\/li>\n<li><strong>Serratiopeptidase<\/strong> is a proteolytic enzyme that degrades inflammatory mediators (notably bradykinin) and breaks down fibrin in oedematous tissue, reducing the viscosity of inflammatory exudate and supporting lymphatic drainage. It also has a mucolytic effect that is exploited separately in rhinosinusitis.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Nucoxia SP Dosing<\/h2>\n<ul>\n<li><strong>Dosp\u011bl\u00ed:<\/strong> one tablet once daily, ideally at the same time each day<\/li>\n<li><strong>Duration:<\/strong> short-course &mdash; typically 3 to 7 days for post-operative or post-traumatic pain; longer courses should be reviewed by a doctor<\/li>\n<li><strong>Na\u010dasov\u00e1n\u00ed:<\/strong> take serratiopeptidase-containing products ideally <em>nala\u010dno<\/em> (1 hour before food, or 2 hours after) because serratiopeptidase absorption is reduced by food. If gastric irritation is a problem, small food with the tablet is acceptable &mdash; the loss of enzyme absorption is a reasonable trade-off against gastric upset.<\/li>\n<li><strong>Nekombinujte<\/strong> with another NSAID.<\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:16px 0;border-radius:4px;\">\n<p style=\"margin:0;\"><strong>GI safety.<\/strong> Nucoxia SP (or its NSAID component) carries real risk of gastritis, peptic ulcer, and upper-GI bleeding. Risk is highest in patients over 65, in those with prior ulcer disease, and in anyone also on low-dose aspirin, corticosteroids, SSRIs, or anticoagulants. Take with food, at the lowest effective dose for the shortest reasonable time, and ask your doctor about adding a proton pump inhibitor (omeprazole, pantoprazole) for courses over 2&ndash;4 weeks.<\/p>\n<\/div>\n<h2 class=\"wp-block-heading\">Who Should Not Take Etoricoxib?<\/h2>\n<ul>\n<li>Known hypersensitivity to etoricoxib or any NSAID<\/li>\n<li>Active peptic ulcer or GI bleed<\/li>\n<li>Inflammatory bowel disease flare<\/li>\n<li>Congestive heart failure (NYHA II&ndash;IV) &mdash; etoricoxib is specifically contraindicated<\/li>\n<li>Established ischaemic heart disease, peripheral arterial disease, or cerebrovascular disease<\/li>\n<li><strong>Nekontrolovan\u00e1 hypertenze<\/strong> (blood pressure consistently above 140\/90 mmHg &mdash; etoricoxib raises BP noticeably)<\/li>\n<li>Severe hepatic dysfunction (Child-Pugh C)<\/li>\n<li>Severe renal impairment (CrCl &lt; 30 mL\/min)<\/li>\n<li>Pregnancy (all trimesters) and breastfeeding<\/li>\n<li>Children under 16 years<\/li>\n<li>Aspirin- or NSAID-induced asthma, urticaria, or angioedema<\/li>\n<li>Recent CABG surgery<\/li>\n<\/ul>\n<p><strong>Serratiopeptidase-specific caution:<\/strong> avoid in patients with bleeding disorders, on anticoagulants (warfarin, DOACs), or in the 2 weeks before and after major surgery &mdash; the fibrinolytic effect can theoretically increase bleeding risk.<\/p>\n<h2 class=\"wp-block-heading\">Vedlej\u0161\u00ed \u00fa\u010dinky<\/h2>\n<ul>\n<li><strong>Etoricoxib component:<\/strong> headache, dizziness, ankle swelling, raised BP, dyspepsia, nausea<\/li>\n<li><strong>Serratiopeptidase component:<\/strong> usually very well tolerated; occasional nausea, anorexia, mild diarrhoea, skin rash; rare eosinophilic pneumonitis reported<\/li>\n<li><strong>Rare (combination):<\/strong> severe skin reactions, GI bleeding, myocardial infarction, stroke, acute kidney injury, severe hepatotoxicity<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Objedn\u00e1vky a dod\u00e1n\u00ed<\/h2>\n<p>MedsBase offers worldwide shipping on every order. Orders are dispatched in discreet packaging and arrive in branded manufacturer packs. If your preferred pack size is out of stock, contact customer support for an ETA.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:20px 0;border-radius:4px;\">\n<p style=\"margin:0;\"><strong>Zdravotn\u00ed prohl\u00e1\u0161en\u00ed.<\/strong> The information on this page is provided for general education only. It is not a substitute for advice from your own doctor or pharmacist. Talk to a qualified healthcare professional before starting, stopping, or changing therapy, especially if you have a history of ulcer disease, heart disease, kidney disease, asthma, liver disease, or are pregnant.<\/p>\n<\/div>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3 class=\"wp-block-heading\">What is Nucoxia SP used for?<\/h3>\n<p>Nucoxia SP (etoricoxib 60 mg + serratiopeptidase 10 mg) is used for musculoskeletal pain with swelling &mdash; post-operative pain, post-traumatic injury, acute arthritis flares, and inflammatory soft-tissue conditions where tissue oedema is prominent.<\/p>\n<h3 class=\"wp-block-heading\">What does serratiopeptidase add?<\/h3>\n<p>Serratiopeptidase is a proteolytic enzyme that reduces tissue oedema by breaking down bradykinin and fibrin at the site of inflammation. It does not act on prostaglandins. The combination with etoricoxib gives pain\/inflammation + anti-swelling coverage in a single tablet.<\/p>\n<h3 class=\"wp-block-heading\">Should I take Nucoxia SP before or after food?<\/h3>\n<p>For maximum enzyme absorption, serratiopeptidase should be taken on an empty stomach &mdash; 1 hour before or 2 hours after meals. If you have gastric sensitivity, a small amount of food is an acceptable compromise.<\/p>\n<h3 class=\"wp-block-heading\">How long should I take Nucoxia SP?<\/h3>\n<p>Short courses of 3 to 7 days are typical for post-operative or post-traumatic pain with swelling. Longer use should be reviewed by a doctor.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Nucoxia SP with another painkiller?<\/h3>\n<p>Paracetamol can be added safely. Do not combine with another NSAID &mdash; the etoricoxib component already provides that action.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Nucoxia SP before or after surgery?<\/h3>\n<p>Avoid in the 1&ndash;2 weeks before and after major surgery unless your surgeon has specifically cleared it. Serratiopeptidase has theoretical fibrinolytic activity that could increase bleeding.<\/p>\n<h3 class=\"wp-block-heading\">Is Nucoxia SP safe for long-term use?<\/h3>\n<p>The etoricoxib component can be used longer-term; the combination is typically reserved for short acute courses. For chronic arthritis, simple etoricoxib (60 or 90 mg) is often a better choice.<\/p>\n<h3 class=\"wp-block-heading\">Can I drink alcohol on Nucoxia SP?<\/h3>\n<p>Light drinking is usually tolerated. Heavy drinking raises GI and cardiovascular risk and should be avoided.<\/p>\n<h3 class=\"wp-block-heading\">Is Nucoxia SP safe in pregnancy?<\/h3>\n<p>No. The etoricoxib component is contraindicated throughout pregnancy and during breastfeeding. Use paracetamol as first-line pain relief in pregnancy.<\/p>\n<h3 class=\"wp-block-heading\">Is serratiopeptidase proven to work?<\/h3>\n<p>Serratiopeptidase has been used clinically since the 1960s, particularly in Japan and India. Evidence for anti-oedema effect is strongest in post-surgical and post-traumatic soft-tissue inflammation. High-quality randomised evidence is more limited than for NSAIDs; the combined formulation is used because of the long clinical experience and the complementary mechanism.<\/p>\n<h3 class=\"wp-block-heading\">What if I miss a dose of Nucoxia SP?<\/h3>\n<p>Take it when you remember unless the next dose is due within 12 hours. Never double up.<\/p>\n<p class=\"medsbase-link-boost-2026-05-10\" data-marker=\"mb-link-boost-emanzen-forte\">Pacienti, kte\u0159\u00ed zjist\u00ed <a href=\"https:\/\/medsbase.com\/cs\/nucoxia-sp\/\">Nucoxia SP (etoricoxib 60 mg + serratiopeptidase)<\/a> effective for post-injury swelling but want an isolated enzyme option sometimes trial <a href=\"https:\/\/medsbase.com\/cs\/emanzen-forte\/\">Emanzen Forte (serratiopeptidase 10 mg)<\/a> as a standalone proteolytic anti-inflammatory without the COX-2 component.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Souvisej\u00edc\u00ed alternativy<\/h3>\n<p>Dal\u0161\u00ed produkty v <strong>Chronick\u00e1 onemocn\u011bn\u00ed<\/strong> kter\u00e9 z\u00e1kazn\u00edci tak\u00e9 prohl\u00ed\u017eej\u00ed:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/endoxan\/\">Endoxan<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/efavir\/\">Efavir<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/trajenta-duo\/\">Trajenta Duo<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/neurobion-forte-rf-injection\/\">Neurobion Forte RF Injekce (Methylkobalamin + B6 + B3) \u2014 Oprava nerv\u016f<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/celeheal\/\">Celeheal<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 \u00da\u010dinn\u011b zm\u00edr\u0148uje bolest<br \/>\n\u2705 Sni\u017euje z\u00e1n\u011bt<br \/>\n\u2705 Alleviates swelling<br \/>\n\u2705 Promotes faster healing<br \/>\n\u2705 Zvy\u0161uje mobilitu<\/p>\n<p>Nucoxia SP contains Etoricoxib and Serratiopeptidase.<\/p>","protected":false},"featured_media":61623,"comment_status":"closed","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3555],"product_tag":[4208,5069,4876],"class_list":{"0":"post-61622","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-pain-relief-medication","9":"product_tag-etoricoxib","10":"product_tag-nucoxia-sp","11":"product_tag-serratiopeptidase","13":"first","14":"instock","15":"shipping-taxable","16":"purchasable","17":"product-type-variable","18":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/61622","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=61622"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/61623"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=61622"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=61622"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=61622"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=61622"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}