{"id":61630,"date":"2024-03-03T08:48:02","date_gmt":"2024-03-03T08:48:02","guid":{"rendered":"https:\/\/medsname.com\/nailrox-nail-lacquer\/"},"modified":"2026-04-30T10:23:33","modified_gmt":"2026-04-30T10:23:33","slug":"nailrox-nail-lacquer","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/nailrox-nail-lacquer\/","title":{"rendered":"Nailrox Nail Lacquer"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 20px;margin:18px 0;border-radius:6px;\">\n<h3 style=\"margin-top:0;\">\ud83d\udca1 Rychl\u00e1 odpov\u011b\u010f<\/h3>\n<p style=\"margin-bottom:0;\">Nailrox Nail Lacquer is ciclopirox 8% w\/v medicated nail lacquer \u2014 a hydroxypyridinone antifungal (mechanism distinct from azoles, allylamines, and morpholines) for onychomycosis caused by Trichophyton rubrum and T. mentagrophytes. Daily application during the first week then progressively less often (week 2 every 2 days, week 3+ once weekly), with weekly removal using nail polish remover. Treatment up to 48 weeks for toenails. Cure rates with topical alone are modest (~30%); combination with oral terbinafine improves outcomes.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f5f5f5;border:1px solid #e1e1e1;padding:18px 22px;margin:24px 0;border-radius:8px;display:flex;flex-wrap:wrap;justify-content:space-around;gap:16px;align-items:center;font-size:0.95em;\">\n<div style=\"text-align:center;flex:1;min-width:140px;\">\ud83c\udfed<br \/><strong>WHO-GMP<\/strong><br \/>certifikovan\u00fd v\u00fdrobce<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n<div style=\"text-align:center;flex:1;min-width:140px;\">\ud83d\udce6<br \/><strong>Diskr\u00e9tn\u00ed balen\u00ed<\/strong><br \/>oby\u010dejn\u00e1 ob\u00e1lka<\/div>\n<div style=\"text-align:center;flex:1;min-width:140px;\">\ud83c\udf0d<br \/><strong>Dod\u00e1n\u00ed po cel\u00e9m sv\u011bt\u011b<\/strong><br \/>do v\u011bt\u0161iny zem\u00ed<\/div>\n<div style=\"text-align:center;flex:1;min-width:140px;\">\u2b50<br \/><strong>1 400+ z\u00e1kazn\u00edk\u016f<\/strong><br \/><a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">\u010d\u00edst recenze<\/a><\/div>\n<\/div>\n<h2>\ud83d\udd12 Why order Nailrox Nail Lacquer from MedsBase<\/h2>\n<ul>\n<li><strong>v\u00fdrobce certifikovan\u00e9ho WHO-GMP<\/strong> \u2014 dod\u00e1v\u00e1no z regulovan\u00e9ho za\u0159\u00edzen\u00ed, kompletn\u00ed balen\u00ed s \u010d\u00edslem \u0161ar\u017ee a datem expirace.<\/li>\n<li><strong>Diskr\u00e9tn\u00ed balen\u00ed<\/strong> \u2014 oby\u010dejn\u00e1 ob\u00e1lka, bez uveden\u00ed n\u00e1zvu l\u00e9ku na vn\u011bj\u0161\u00ed stran\u011b.<\/li>\n<li><strong>Dod\u00e1n\u00ed po cel\u00e9m sv\u011bt\u011b<\/strong> do v\u011bt\u0161iny zem\u00ed s <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\">Reshipment Assurance<\/a>.<\/li>\n<li><strong>V\u011brnostn\u00ed body<\/strong> \u2014 1 bod za ka\u017ed\u00fd utracen\u00fd 1$ (neplat\u00ed pro peptidy\/dopravu); 100 bod\u016f = 5$ sleva na dal\u0161\u00ed objedn\u00e1vku.<\/li>\n<\/ul>\n<h2 id=\"uses\">Pou\u017eit\u00ed<\/h2>\n<p>Nailrox Nail Lacquer (ciclopirox 8% w\/v nail lacquer, Glenmark) is approved for mild-to-moderate onychomycosis caused by dermatophytes (Trichophyton rubrum, T. mentagrophytes). Like amorolfine, it is most effective for distal-edge disease that does not involve the nail matrix.<\/p>\n<h2 id=\"how-to-apply\">How to apply \u2014 schedule matters<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;font-size:0.95em;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">T\u00fdden<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">Frekvence<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">T\u00fdden 1<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Apply once daily, ideally at bedtime<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">T\u00fdden 2<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Apply every other day<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Week 3 onwards<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Apply once weekly<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Once a week<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Remove existing lacquer with nail polish remover, file the nail, then re-apply<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul>\n<li>File rough surface of the affected nails.<\/li>\n<li>Apply a thin layer to the entire nail and 5 mm of surrounding skin (drug also penetrates lateral nail folds).<\/li>\n<li>Wait 30 seconds to let it dry.<\/li>\n<li>Once weekly: use nail polish remover (acetone or ethyl acetate) to remove all built-up lacquer, file rough surface, then re-apply.<\/li>\n<li>Treatment may continue up to 48 weeks for toenails.<\/li>\n<\/ul>\n<h2 id=\"mechanism\">Jak to funguje<\/h2>\n<p>Ciclopirox is a hydroxypyridinone antifungal \u2014 chemically distinct from azoles, allylamines, and morpholines. It chelates trivalent metal cations (iron, aluminium) required by fungal mitochondrial enzymes. The result is impaired energy production and reduced uptake of essential precursors. Active against dermatophytes, Candida, Malassezia, and some bacteria \u2014 broader spectrum than most other topical antifungals. Penetrates the nail plate over weeks of repeat application.<\/p>\n<h2 id=\"side-effects\">Vedlej\u0161\u00ed \u00fa\u010dinky<\/h2>\n<ul>\n<li>Common \u2014 periungual erythema, mild burning at application, brittleness or shape change of the affected nail.<\/li>\n<li>Uncommon \u2014 contact dermatitis, onycholysis.<\/li>\n<li>Rare \u2014 severe contact allergy.<\/li>\n<\/ul>\n<h2 id=\"pregnancy\">T\u011bhotenstv\u00ed a kojen\u00ed<\/h2>\n<p>Limited data. Minimal systemic absorption. Onychomycosis is not life-threatening \u2014 many clinicians defer treatment until after pregnancy. Topical ciclopirox use in breastfeeding is generally considered low-risk; avoid hand-to-mouth contact with the infant after application.<\/p>\n<h3 class=\"wp-block-heading\">Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<ul>\n<li><strong>v\u00fdrobce certifikovan\u00e9ho WHO-GMP<\/strong> \u2014 poch\u00e1z\u00ed z regulovan\u00e9ho za\u0159\u00edzen\u00ed, balen\u00ed s \u010d\u00edslem \u0161ar\u017ee a datem expirace.<\/li>\n<li><strong>Diskr\u00e9tn\u00ed balen\u00ed<\/strong> \u2014 oby\u010dejn\u00e1 ob\u00e1lka, bez n\u00e1zvu l\u00e9ku na vn\u011bj\u0161\u00ed stran\u011b.<\/li>\n<li><strong>Dod\u00e1n\u00ed po cel\u00e9m sv\u011bt\u011b<\/strong> s <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji bezplatn\u011b (v souladu s podm\u00ednkami politiky).<\/li>\n<li><strong>V\u011brnostn\u00ed body<\/strong> \u2014 1 bod za<br \/>\n<h2>\u010casto kladen\u00e9 ot\u00e1zky utracen\u00e9 (neplat\u00ed pro peptidy); 100 bod\u016f = sleva.<\/li>\n<\/ul>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3>Daily then weekly \u2014 why the change?<\/h3>\n<p>First-week loading establishes drug levels in the nail. From week 3 the lacquer accumulates a depot in the nail plate and weekly application is enough to maintain fungicidal levels. This is also why the weekly polish-remover step matters \u2014 clears the built-up film so a fresh application can penetrate.<\/p>\n<h3>How long until I can stop?<\/h3>\n<p>Depends on response. Toenails: up to 48 weeks of treatment, then assess. Fingernails: typically 6 months. The visible nail may not look fully normal even at the end of treatment \u2014 the dead infected portion grows out for months after.<\/p>\n<h3>Ciclopirox vs amorolfine \u2014 which is better?<\/h3>\n<p>Cure rates from topical-only therapy are similar (modest ~30\u201340%) and both are inferior to oral terbinafine for moderate-to-severe disease. Choose by leaflet preference (daily-then-weekly ciclopirox vs. weekly amorolfine) and patient adherence.<\/p>\n<h3>Can I combine with oral terbinafine?<\/h3>\n<p>Yes \u2014 combination (oral terbinafine 12 weeks + topical ciclopirox 9\u201312 months) gives higher cure rates than either alone, especially for thick or matrix-involved toenail disease.<\/p>\n<h3>Why all the polish-remover faff?<\/h3>\n<p>Ciclopirox lacquer is a film-forming polymer. Layers of it build up. Once weekly removal with acetone-based polish remover lets a fresh layer penetrate the underlying nail. Skipping this step makes the next application sit on old polymer rather than soaking into the nail.<\/p>\n<h3>Is Nailrox Nail Lacquer the same as Penlac?<\/h3>\n<p>Yes \u2014 Penlac (in the US) is the original brand. Nailrox Nail Lacquer contains the same active ingredient (ciclopirox 8%), manufactured by Glenmark under WHO-GMP. Bioequivalent.<\/p>\n<h3>What if my nail is very thick?<\/h3>\n<p>See a podiatrist for nail debridement before starting. Topical lacquer cannot penetrate a 5-mm-thick nail. Combine debridement + oral terbinafine + topical lacquer for the best outcome.<\/p>\n<h3>Can I get a pedicure during treatment?<\/h3>\n<p>Yes \u2014 but use your own files and instruments. Salon files used on infected nails spread fungus to other clients. Disposable single-use files are best.<\/p>\n<h3>Why does my nail look worse after a few weeks?<\/h3>\n<p>Brittleness and surface roughness are common during treatment; the drug disrupts the nail surface as it penetrates. Continue the schedule. As new healthy nail grows in, the appearance improves.<\/p>\n<h3>Can I wear cosmetic nail polish over the lacquer?<\/h3>\n<p>Generally not advised on top of ciclopirox \u2014 most leaflets recommend keeping the medicated lacquer alone. If you want cosmetic polish for an occasion, remove the medicated film, apply cosmetic polish for the day, then remove and re-start the schedule.<\/p>\n<h2 id=\"storage\">Skladov\u00e1n\u00ed<\/h2>\n<p>Store the bottle tightly capped at 15\u201325 \u00b0C, away from heat and flames (the solvent is flammable). Keep out of reach of children. Do not use after expiry.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h2>Dal\u0161\u00ed antifung\u00e1ln\u00ed l\u00e9ky, kter\u00e9 by v\u00e1s mohly zaj\u00edmat<\/h2>\n<p>If Nailrox Nail Lacquer is unavailable, here are alternatives.<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/zimig\/\"><strong>Zimig (terbinafin 250 mg)<\/strong><\/a> \u2014 Peror\u00e1ln\u00ed l\u00e9\u010dba prvn\u00ed volby pro dermatofytn\u00ed onychomyk\u00f3zu; vy\u0161\u0161\u00ed \u00fasp\u011b\u0161nost l\u00e9\u010dby.<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/sporanox-capsule\/\"><strong>Sporanox (itraconazol 100 mg)<\/strong><\/a> \u2014 Pulzn\u00ed terapie jako alternativa pro onychomyk\u00f3zu.<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/loceryl-nail-liq\/\"><strong>Loceryl (amorolfin 5% lak)<\/strong><\/a> \u2014 Jin\u00fd topick\u00fd lak (morfolin), t\u00fddenn\u00ed aplikace.<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/nailrox-nail-lacquer\/\"><strong>Nailrox (ciklopirox 8% lak)<\/strong><\/a> \u2014 Jin\u00fd topick\u00fd lak (hydroxypyridinon).<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/keto-cream\/\"><strong>Keto Cream (ketokonazol 2%)<\/strong><\/a> \u2014 Pro sou\u010dasn\u011b se vyskytuj\u00edc\u00ed tinea pedis.<\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:12px 18px;margin:24px 0;font-size:0.95em;\"><strong>Zdravotn\u00ed prohl\u00e1\u0161en\u00ed.<\/strong> Tato str\u00e1nka obsahuje informace o produktu pro dosp\u011bl\u00e9, kte\u0159\u00ed si objedn\u00e1vaj\u00ed antifung\u00e1ln\u00ed l\u00e9ky pro osobn\u00ed pot\u0159ebu. Nenahrazuje individu\u00e1ln\u00ed l\u00e9ka\u0159skou radu. Proberte vhodn\u00e9 antifung\u00e1ln\u00ed l\u00e9\u010divo, d\u00e1vkov\u00e1n\u00ed a d\u00e9lku l\u00e9\u010dby s kvalifikovan\u00fdm l\u00e9ka\u0159em \u2013 zejm\u00e9na pokud m\u00e1te onemocn\u011bn\u00ed jater, jste t\u011bhotn\u00e1 nebo koj\u00edte, u\u017e\u00edv\u00e1te warfarin, statiny, imunosupresiva nebo m\u00e1te pl\u00eds\u0148ovou infekci neht\u016f, kter\u00e1 m\u016f\u017ee b\u00fdt jinou diagn\u00f3zou (psori\u00e1za, lichen planus, trauma).<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u2705 Fights nail fungus<br \/>\n\u2705 Prevents fungal growth<br \/>\n\u2705 Posiluje nehty<br \/>\n\u2705 Promotes nail health<br \/>\n\u2705 Easy topical application<\/p>\n<p>Nailrox Nail Lacquer contains Ciclopirox.<\/p>","protected":false},"featured_media":61631,"comment_status":"closed","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3501,3642,3141,3504,3342],"product_tag":[5070,5071,5072],"class_list":{"0":"post-61630","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-fungal","7":"product_cat-beauty-skin-care","8":"product_cat-category-overview","9":"product_cat-fungal-infection-treatment","10":"product_cat-general-health","11":"product_tag-ciclopirox","12":"product_tag-nailrox","13":"product_tag-nailrox-nail-lacquer","15":"first","16":"instock","17":"shipping-taxable","18":"purchasable","19":"product-type-variable","20":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/61630","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=61630"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/61631"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=61630"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=61630"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=61630"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=61630"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}