{"id":62135,"date":"2024-03-10T06:02:02","date_gmt":"2024-03-10T06:02:02","guid":{"rendered":"https:\/\/medsname.com\/malegra-fxt-plus\/"},"modified":"2026-05-04T05:53:15","modified_gmt":"2026-05-04T05:53:15","slug":"malegra-fxt-plus","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/malegra-fxt-plus\/","title":{"rendered":"Malegra FXT Plus"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Malegra FXT Plus?<\/h3>\n<p style=\"margin:0;\"><strong>Malegra FXT Plus<\/strong> obsahuje <strong>sildenafil 100 mg + fluoxetine 60 mg<\/strong> a pou\u017e\u00edv\u00e1 se p\u0159i erektiln\u00ed dysfunkci s p\u0159ed\u010dasnou ejakulac\u00ed. Dostupn\u00e9 v <strong>sildenafil 100 mg + fluoxetine 60 mg<\/strong>. Klinick\u00fd \u00fa\u010dinek trv\u00e1 p\u0159ibli\u017en\u011b <strong>4\u20136 hours for ED; fluoxetine steady-state over weeks<\/strong>. Vyrobeno spole\u010dnost\u00ed Sunrise Remedies.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Co z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdrobce certifikovan\u00fd WHO-GMP \u00b7 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 doprava \u00b7 V\u00edce ne\u017e 1 400 ov\u011b\u0159en\u00fdch <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n<p><strong>Malegra FXT Plus<\/strong> kombinuje <strong>sildenafil 100 mg<\/strong> (a short-acting PDE5 inhibitor for erectile dysfunction) with <strong>fluoxetine 60 mg<\/strong> (a long-acting SSRI that can delay ejaculation). Unlike dapoxetine-based combinations, fluoxetine is a <strong>daily-use SSRI<\/strong> \u2014 the ejaculation-delay effect builds over weeks of regular use rather than immediately from a single dose.<\/p>\n<p>Manufactured by Sunrise Remedies, Malegra FXT Plus is intended for men with <strong>soub\u011b\u017enou ED a PE<\/strong> who are already on (or planning to start) daily SSRI therapy for PE.<\/p>\n<h2 class=\"wp-block-heading\">What Is Malegra FXT Plus?<\/h2>\n<p>Malegra FXT Plus is a combination tablet containing:<\/p>\n<ul>\n<li><strong>Sildenafil 100 mg<\/strong> \u2014 a PDE5 inhibitor that improves erectile response; effects last 4\u20136 hours<\/li>\n<li><strong>Fluoxetine 60 mg<\/strong> \u2014 an SSRI that extends ejaculatory latency when taken regularly over weeks<\/li>\n<\/ul>\n<p><strong>D\u016fle\u017eit\u00e9:<\/strong> unlike dapoxetine, fluoxetine is <strong>ne<\/strong> an on-demand PE drug \u2014 it requires continuous daily dosing (typically 4\u20136 weeks to take full effect) and should be reviewed by a doctor before starting. Many clinicians prefer dapoxetine (as in <a href=\"https:\/\/medsbase.com\/cs\/super-tadalis-sx\/\" rel=\"noopener\">Super Tadalis Sx<\/a> nebo <a href=\"https:\/\/medsbase.com\/cs\/super-vilitra\/\" rel=\"noopener\">Super Vilitra<\/a>) for the PE side of combined treatment because it is specifically engineered for on-demand use.<\/p>\n<h2 class=\"wp-block-heading\">How Does Malegra FXT Plus Work?<\/h2>\n<ul>\n<li><strong>Sildenafil<\/strong> blocks PDE5 in the corpus cavernosum, prolonging cyclic GMP activity and allowing increased blood inflow during sexual arousal<\/li>\n<li><strong>Fluoxetine<\/strong> selectively inhibits the serotonin transporter; raised synaptic serotonin delays the ejaculatory reflex. This effect builds over 2\u20136 weeks of daily use<\/li>\n<\/ul>\n<p>Because fluoxetine&#8217;s active metabolite (norfluoxetine) has a half-life of 7\u201315 days, the SSRI effect accumulates slowly and persists long after stopping.<\/p>\n<h2 class=\"wp-block-heading\">Pou\u017eit\u00ed a indikace<\/h2>\n<ul>\n<li><strong>Co-existing erectile dysfunction and premature ejaculation<\/strong> \u2014 where daily SSRI therapy is acceptable<\/li>\n<li><strong>ED with depressive symptoms<\/strong> \u2014 rarely, where the fluoxetine component is also treating mood<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Malegra FXT Plus Dosage and Administration<\/h2>\n<table>\n<thead>\n<tr>\n<th>Sc\u00e9n\u00e1\u0159<\/th>\n<th>Doporu\u010den\u00fd postup<\/th>\n<th>Pozn\u00e1mky<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>First-time combination use<\/strong><\/td>\n<td>1 tablet daily under medical supervision<\/td>\n<td>Sildenafil effect is per-tablet on-demand; fluoxetine effect builds over 2\u20136 weeks<\/td>\n<\/tr>\n<tr>\n<td><strong>ED \u2014 single dose<\/strong><\/td>\n<td>100 mg sildenafil component works per tablet<\/td>\n<td>30\u201360 min before activity<\/td>\n<\/tr>\n<tr>\n<td><strong>PE \u2014 sustained effect<\/strong><\/td>\n<td>Fluoxetine requires 2\u20136 weeks of daily dosing<\/td>\n<td>Not effective as a one-off &#8220;pop-a-pill&#8221; for PE<\/td>\n<\/tr>\n<tr>\n<td><strong>Lehk\u00e9 po\u0161kozen\u00ed jater<\/strong><\/td>\n<td>Reduce dose; caution<\/td>\n<td>Fluoxetine is heavily hepatically cleared<\/td>\n<\/tr>\n<tr>\n<td><strong>Severe hepatic or renal impairment<\/strong><\/td>\n<td>Vyhnout se<\/td>\n<td>Use separate lower-dose components<\/td>\n<\/tr>\n<tr>\n<td><strong>Maximum sildenafil exposure<\/strong><\/td>\n<td>1 tableta ka\u017ed\u00fdch 24 hodin<\/td>\n<td>Do not exceed \u2014 contains a full 100 mg sildenafil dose<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3 class=\"wp-block-heading\">How to Take Malegra FXT Plus Properly<\/h3>\n<ul>\n<li>Swallow whole with water \u2014 food has modest impact; a fatty meal slows sildenafil onset<\/li>\n<li>For PE benefit, take daily at roughly the same time (fluoxetine steady-state takes 2\u20136 weeks)<\/li>\n<li>For ED benefit, take 30\u201360 min before activity<\/li>\n<li>Do not exceed one tablet per 24 hours<\/li>\n<li>Do not combine with MAOIs \u2014 14-day washout required<\/li>\n<li>Avoid abrupt discontinuation after weeks of use \u2014 fluoxetine has a long tail but some men experience SSRI-discontinuation symptoms<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Side Effects of Malegra FXT Plus<\/h2>\n<table>\n<thead>\n<tr>\n<th>Slo\u017eka \/ Z\u00e1va\u017enost<\/th>\n<th>Vedlej\u0161\u00ed \u00fa\u010dinek<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Sildenafil \u2014 \u010dast\u00e9<\/strong><\/td>\n<td>Headache, flushing, dyspepsia, nasal congestion, visual disturbance<\/td>\n<\/tr>\n<tr>\n<td><strong>Fluoxetine \u2014 common<\/strong><\/td>\n<td>Nausea, insomnia, sexual dysfunction (ironic but real \u2014 delayed\/absent orgasm), anxiety, weight change, somnolence<\/td>\n<\/tr>\n<tr>\n<td><strong>Fluoxetine \u2014 less common<\/strong><\/td>\n<td>Suicidal ideation (especially in first weeks), QT prolongation, bleeding risk, hyponatraemia in elderly<\/td>\n<\/tr>\n<tr>\n<td><strong>Vz\u00e1cn\u00e9<\/strong><\/td>\n<td>Serotonin syndrome (with other serotonergic drugs), Stevens-Johnson syndrome, priapism<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>Black-box style caution:<\/strong> SSRI initiation can transiently increase suicidal thoughts, particularly in young adults. Regular contact with a prescriber during the first weeks of use is essential.<\/p>\n<h2 class=\"wp-block-heading\">Varov\u00e1n\u00ed a opat\u0159en\u00ed<\/h2>\n<ul>\n<li><strong>Kardiovaskul\u00e1rn\u00ed kondice pro pohlavn\u00ed styk<\/strong> \u2014 sexu\u00e1ln\u00ed aktivita klade n\u00e1roky na srdce. Mu\u017ei s aktivn\u00ed anginou pectoris, ned\u00e1vn\u00fdm infarktem myokardu (do 90 dn\u016f), nekontrolovanou arytmi\u00ed nebo t\u011b\u017ek\u00fdm srde\u010dn\u00edm selh\u00e1n\u00edm by m\u011bli p\u0159ed zah\u00e1jen\u00edm u\u017e\u00edv\u00e1n\u00ed inhibitoru PDE5 podstoupit kardiologick\u00e9 vy\u0161et\u0159en\u00ed<\/li>\n<li><strong>Krevn\u00ed tlak<\/strong> \u2014 inhibitory PDE5 zp\u016fsobuj\u00ed m\u00edrn\u00e9, p\u0159echodn\u00e9 sn\u00ed\u017een\u00ed TK; pou\u017e\u00edvejte opatrn\u011b p\u0159i u\u017e\u00edv\u00e1n\u00ed v\u00edce antihypertenziv<\/li>\n<li><strong>Priapismus<\/strong> \u2014 vy\u0161\u0161\u00ed riziko u mu\u017e\u016f se srpkovitou an\u00e9mi\u00ed, mnoho\u010detn\u00fdm myelomem nebo leuk\u00e9mi\u00ed; vyhledejte neodkladnou p\u00e9\u010di, pokud erekce trv\u00e1 d\u00e9le ne\u017e 4 hodiny<\/li>\n<li><strong>Zrak<\/strong> \u2014 p\u0159eru\u0161te u\u017e\u00edv\u00e1n\u00ed a vyhledejte l\u00e9ka\u0159e p\u0159i n\u00e1hl\u00fdch zm\u011bn\u00e1ch zraku; byly hl\u00e1\u0161eny vz\u00e1cn\u00e9 p\u0159\u00edpady nearteritick\u00e9 p\u0159edn\u00ed ischemick\u00e9 optick\u00e9 neuropatie (NAION)<\/li>\n<li><strong>Sluch<\/strong> \u2014 ojedin\u011bl\u00e9 zpr\u00e1vy o n\u00e1hl\u00e9 senzorineur\u00e1ln\u00ed ztr\u00e1t\u011b sluchu \u2014 v p\u0159\u00edpad\u011b v\u00fdskytu p\u0159eru\u0161te u\u017e\u00edv\u00e1n\u00ed a pora\u010fte se s l\u00e9ka\u0159em<\/li>\n<li><strong>Alkohol<\/strong> \u2014 v\u00fdznamn\u00fd p\u0159\u00edjem alkoholu v kombinaci s jak\u00fdmkoli inhibitorem PDE5 m\u016f\u017ee zes\u00edlit z\u00e1vrat\u011b, bolesti hlavy a n\u00edzk\u00fd krevn\u00ed tlak<\/li>\n<li><strong>Grapefruitov\u00e1 \u0161\u0165\u00e1va<\/strong> \u2014 inhibuje CYP3A4 a m\u016f\u017ee zv\u00fd\u0161it hladinu l\u00e9\u010diva v krvi<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Kontraindikace \u2014 Kdo by TENTO L\u00c9K NEM\u011aL u\u017e\u00edvat<\/h2>\n<ul>\n<li><strong>Sou\u010dasn\u00e9 u\u017e\u00edv\u00e1n\u00ed jak\u00e9hokoli nitr\u00e1tu<\/strong> \u2014 GTN, isosorbid mononitr\u00e1t\/dinitr\u00e1t, nikorandil, amylnitrit (\u201cpoppers\u201d)<\/li>\n<li><strong>Sou\u010dasn\u00e9 u\u017e\u00edv\u00e1n\u00ed stimul\u00e1tor\u016f guanyl\u00e1tcykl\u00e1zy<\/strong> jako je riociguat<\/li>\n<li>Ned\u00e1vn\u00fd infarkt myokardu (do 90 dn\u016f), nestabiln\u00ed angina pectoris nebo angina p\u0159i pohlavn\u00edm styku<\/li>\n<li>Srde\u010dn\u00ed selh\u00e1n\u00ed NYHA t\u0159\u00eddy II nebo vy\u0161\u0161\u00ed v posledn\u00edch 6 m\u011bs\u00edc\u00edch<\/li>\n<li>Nekontrolovan\u00e1 arytmie, hypotenze (TK 170\/100)<\/li>\n<li>C\u00e9vn\u00ed mozkov\u00e1 p\u0159\u00edhoda v posledn\u00edch 6 m\u011bs\u00edc\u00edch<\/li>\n<li>Prok\u00e1zan\u00e1 nearteritick\u00e1 p\u0159edn\u00ed ischemick\u00e1 optick\u00e1 neuropatie (NAION) na jednom nebo obou o\u010d\u00edch<\/li>\n<li>T\u011b\u017ek\u00e9 jatern\u00ed po\u0161kozen\u00ed (Child-Pugh C)<\/li>\n<li>P\u0159ecitliv\u011blost na \u00fa\u010dinnou l\u00e1tku nebo kteroukoli pomocnou l\u00e1tku<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Interakce s l\u00e9\u010divy<\/h2>\n<table>\n<thead>\n<tr>\n<th>L\u00e9\u010divo \/ T\u0159\u00edda<\/th>\n<th>Interakce<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Nitr\u00e1ty (GTN, ISMN, ISDN, amylnitrit\/\u201dpoppers\u201d)<\/strong><\/td>\n<td><strong>Absolutn\u00ed kontraindikace<\/strong> \u2014 z\u00e1va\u017en\u00e1, potenci\u00e1ln\u011b fat\u00e1ln\u00ed hypotenze<\/td>\n<\/tr>\n<tr>\n<td><strong>Alfa-blok\u00e1tory (doxazosin, tamsulosin, alfuzosin)<\/strong><\/td>\n<td>Aditivn\u00ed sn\u00ed\u017een\u00ed krevn\u00edho tlaku \u2014 nejprve stabilizujte d\u00e1vku alfa-blok\u00e1toru, za\u010dn\u011bte nejni\u017e\u0161\u00ed d\u00e1vkou PDE5<\/td>\n<\/tr>\n<tr>\n<td><strong>Inhibitory CYP3A4 (ketokonazol, itrakonazol, ritonavir, klarithromycin)<\/strong><\/td>\n<td>Zvy\u0161uj\u00ed hladiny PDE5 v plazm\u011b \u2014 sni\u017ete d\u00e1vkov\u00e1n\u00ed nebo se kombinaci vyhn\u011bte<\/td>\n<\/tr>\n<tr>\n<td><strong>Induktory CYP3A4 (rifampicin, fenytoin, karbamazepin, t\u0159ezalka te\u010dkovan\u00e1)<\/strong><\/td>\n<td>Sni\u017euj\u00ed hladiny PDE5 v plazm\u011b \u2014 \u00fa\u010dinnost m\u016f\u017ee b\u00fdt sn\u00ed\u017eena<\/td>\n<\/tr>\n<tr>\n<td><strong>Riociguat a dal\u0161\u00ed stimul\u00e1tory sGC<\/strong><\/td>\n<td>Kontraindikov\u00e1no \u2014 riziko t\u011b\u017ek\u00e9 hypotenze<\/td>\n<\/tr>\n<tr>\n<td><strong>Jin\u00e9 inhibitory PDE5<\/strong><\/td>\n<td>Nekombinujte \u2014 aditivn\u00ed vedlej\u0161\u00ed \u00fa\u010dinky bez zv\u00fd\u0161en\u00ed \u00fa\u010dinnosti<\/td>\n<\/tr>\n<tr>\n<td><strong>Antihypertenziva<\/strong><\/td>\n<td>Mal\u00fd aditivn\u00ed pokles TK \u2014 obvykle klinicky nev\u00fdznamn\u00fd<\/td>\n<\/tr>\n<tr>\n<td><strong>Grapefruitov\u00e1 \u0161\u0165\u00e1va<\/strong><\/td>\n<td>Inhibuje CYP3A4 \u2014 vyvarujte se velk\u00e9ho nebo pravideln\u00e9ho p\u0159\u00edjmu<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>P\u0159ed zah\u00e1jen\u00edm u\u017e\u00edv\u00e1n\u00ed tohoto l\u00e9ku v\u017edy sd\u011blte sv\u00e9mu p\u0159edepisuj\u00edc\u00edmu l\u00e9ka\u0159i \u00fapln\u00fd seznam sou\u010dasn\u011b u\u017e\u00edvan\u00fdch l\u00e9k\u016f, v\u010detn\u011b voln\u011b prodejn\u00fdch p\u0159\u00edpravk\u016f, rekrea\u010dn\u00edch drog a bylinn\u00fdch dopl\u0148k\u016f.<\/p>\n<h2 class=\"wp-block-heading\">Co d\u011blat v p\u0159\u00edpad\u011b p\u0159ed\u00e1vkov\u00e1n\u00ed<\/h2>\n<p>P\u0159\u00edznaky p\u0159ed\u00e1vkov\u00e1n\u00ed PDE5 zahrnuj\u00ed silnou bolest hlavy, v\u00fdraznou hypotenzi, z\u00e1vrat\u011b, bolest zad nebo sval\u016f a prodlou\u017eenou erekci. L\u00e9\u010dba je podp\u016frn\u00e1, s resuscitac\u00ed tekutinami a monitorov\u00e1n\u00edm srde\u010dn\u00ed \u010dinnosti. Pokud m\u00e1te podez\u0159en\u00ed na p\u0159ed\u00e1vkov\u00e1n\u00ed, okam\u017eit\u011b kontaktujte m\u00edstn\u00ed toxikologick\u00e9 st\u0159edisko nebo pohotovost.<\/p>\n<h2 class=\"wp-block-heading\">Pokyny k uchov\u00e1v\u00e1n\u00ed<\/h2>\n<ul>\n<li>Skladujte pod 30 \u00b0C na such\u00e9m m\u00edst\u011b, mimo p\u0159\u00edm\u00e9 slune\u010dn\u00ed sv\u011btlo<\/li>\n<li>Uchov\u00e1vejte v p\u016fvodn\u00edm blistru a\u017e do pou\u017eit\u00ed<\/li>\n<li>Uchov\u00e1vejte mimo dosah d\u011bt\u00ed a dom\u00e1c\u00edch zv\u00ed\u0159at<\/li>\n<li>Nepou\u017e\u00edvejte po datu expirace uveden\u00e9m na obalu<\/li>\n<li>Nepou\u017eit\u00e9 tablety likvidujte prost\u0159ednictv\u00edm l\u00e9k\u00e1rny, pokud je k dispozici<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Souvisej\u00edc\u00ed alternativy na MedsBase<\/h2>\n<p>Hled\u00e1te souvisej\u00edc\u00ed mo\u017enosti l\u00e9\u010dby ED nebo sexu\u00e1ln\u00edho zdrav\u00ed?<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/modula\/\" rel=\"noopener\">Modula<\/a> \u2014 tadalafil 5 mg, ide\u00e1ln\u00ed pro jednou denn\u00ed n\u00edzkou d\u00e1vku<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/vidalista\/\" rel=\"noopener\">Vidalista<\/a> \u2014 Centurion Labs tadalafil, 2,5 a\u017e 80 mg<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/tadacip\/\" rel=\"noopener\">Tadacip<\/a> \u2014 Cipla tadalafil 20 mg<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/megalis\/\" rel=\"noopener\">Megalis<\/a> \u2014 Macleods tadalafil 10 mg \/ 20 mg<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/suhagra\/\" rel=\"noopener\">Suhagra<\/a> \u2014 Cipla sildenafil 25\/50\/100 mg<\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/erectile-dysfunction\/\" rel=\"noopener\">Prohl\u00e9dnout v\u0161echny l\u00e9\u010debn\u00e9 p\u0159\u00edpravky na erektiln\u00ed dysfunkci \u2192<\/a><\/li>\n<\/ul>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3 class=\"wp-block-heading\">Is Malegra FXT Plus on-demand or daily?<\/h3>\n<p><strong>Mixed.<\/strong> The sildenafil component is on-demand (per-tablet ED effect). The fluoxetine component is daily \u2014 and requires 2\u20136 weeks of regular dosing to reach full PE-delay effect. Fluoxetine is NOT useful as a single-dose PE drug.<\/p>\n<h3 class=\"wp-block-heading\">Why not just use dapoxetine instead?<\/h3>\n<p>Dapoxetine is engineered for on-demand use with a short half-life \u2014 simpler, cleaner pharmacology for PE. Fluoxetine is only appropriate when you want long-term SSRI cover (for mood or chronic PE) and are willing to tolerate daily SSRI side effects. For most men with co-existing ED + PE, a dapoxetine-based combination like <a href=\"https:\/\/medsbase.com\/cs\/super-tadalis-sx\/\" rel=\"noopener\">Super Tadalis Sx<\/a> nebo <a href=\"https:\/\/medsbase.com\/cs\/super-vilitra\/\" rel=\"noopener\">Super Vilitra<\/a> is more practical.<\/p>\n<h3 class=\"wp-block-heading\">When does the PE-delay effect start?<\/h3>\n<p>Fluoxetine requires <strong>2\u20136 weeks<\/strong> of daily use to reach full effect. If you expect an immediate effect from the first tablet, this product will disappoint \u2014 switch to a dapoxetine-based combination.<\/p>\n<h3 class=\"wp-block-heading\">How long does the sildenafil effect last?<\/h3>\n<p>4\u20136 hours per tablet, as with any sildenafil product.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Malegra FXT Plus with alcohol?<\/h3>\n<p>Moderate alcohol with sildenafil alone is usually fine. Fluoxetine amplifies alcohol&#8217;s sedation and impairs judgement \u2014 best to limit strictly.<\/p>\n<h3 class=\"wp-block-heading\">Does fluoxetine cause sexual side effects?<\/h3>\n<p>Ironically, yes \u2014 delayed or absent orgasm is one of fluoxetine&#8217;s most common side effects, which is actually what produces the PE-delay benefit. In some men this becomes excessive (&#8220;anorgasmia&#8221;) and may require dose reduction or switching drugs.<\/p>\n<h3 class=\"wp-block-heading\">Can I stop Malegra FXT Plus abruptly?<\/h3>\n<p>Fluoxetine has a long half-life, so discontinuation symptoms are rarer than with short-half-life SSRIs. Even so, taper under medical guidance rather than stopping suddenly after weeks of use.<\/p>\n<h3 class=\"wp-block-heading\">Is Malegra FXT Plus safe for men with heart conditions?<\/h3>\n<p>Contraindicated with nitrates, within 90 days of MI, or in unstable angina. Fluoxetine can modestly prolong QT \u2014 caution with other QT-prolonging drugs. Cardiac review recommended.<\/p>\n<h3 class=\"wp-block-heading\">What if Malegra FXT Plus doesn&#8217;t work for my PE?<\/h3>\n<p>Allow 6 weeks of daily use first. If still inadequate, switch to a dapoxetine-based combination, add behavioural therapy (stop-start technique), or consider topical anaesthetics under medical supervision.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Malegra FXT Plus if I&#8217;m already on another SSRI?<\/h3>\n<p><strong>Ne.<\/strong> Do not combine fluoxetine with another SSRI \u2014 serotonin syndrome risk. Wash out the existing SSRI under medical supervision before starting fluoxetine.<\/p>\n<p><!-- medsbase-faq-h3-converted --><\/p>\n<p class=\"medsbase-link-boost-2026-05-04\" data-marker=\"mb-link-boost-malegra-fxt\"><a href=\"https:\/\/medsbase.com\/cs\/malegra-fxt-plus\/\">Malegra FXT Plus<\/a> is the higher-strength sildenafil 100 mg + fluoxetine 60 mg tablet; for users who tolerate fluoxetine 40 mg and prefer the lower SSRI shoulder, the standard-strength <a href=\"https:\/\/medsbase.com\/cs\/malegra-fxt\/\">Malegra FXT (sildenafil 100 mg + fluoxetin 40 mg)<\/a> is the corresponding step-down option in the same brand line.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Souvisej\u00edc\u00ed alternativy<\/h3>\n<p>Dal\u0161\u00ed produkty v <strong>Mu\u017esk\u00e9 zdrav\u00ed<\/strong> kter\u00e9 z\u00e1kazn\u00edci tak\u00e9 prohl\u00ed\u017eej\u00ed:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/tadarise\/\">Tadarise<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/vriligy\/\">Vriligy<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/super-vilitra\/\">Super Vilitra<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/p-force-fort\/\">P-Force Fort<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/finrest\/\">Finrest<\/a><\/li>\n<\/ul>\n<p><!-- medsbase-guide-dapoxetine --><\/p>\n<p style=\"margin:20px 0 0;padding:12px 16px;background:#f4f8fb;border-left:3px solid #2c7cb0;border-radius:3px;font-size:14px\">\ud83d\udcda <strong>Zjistit v\u00edce:<\/strong> <a href=\"https:\/\/medsbase.com\/cs\/what-is-dapoxetine-and-how-its-used-for-pe-treatment\/\">Kupte si Dapoxetine online (2026): Samostatn\u00e9 a kombinovan\u00e9 produkty \u2014 bez p\u0159edpisu<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>\u2705 L\u00e9\u010d\u00ed erektiln\u00ed dysfunkci<br \/>\n\u2705 Oddaluje p\u0159ed\u010dasnou ejakulaci<br \/>\n\u2705 Enhances stamina<br \/>\n\u2705 Zlep\u0161uje n\u00e1ladu<br \/>\n\u2705 Posiluje sebev\u011bdom\u00ed<\/p>\n<p>Malegra FXT Plus contains Sildenafil 100 mg + Fluoxetine 60 mg.<\/p>","protected":false},"featured_media":62136,"comment_status":"closed","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3143,3142,3145,3151],"product_tag":[5659,5658,3173,5103,5655,3153,5657],"class_list":{"0":"post-62135","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-erectile-dysfunction","8":"product_cat-mens-health","9":"product_cat-premature-ejaculation-treatment","10":"product_cat-sildenafil","11":"product_tag-combination-tablet","12":"product_tag-ed-pe","13":"product_tag-fluoxetine","14":"product_tag-malegra-fxt-plus","15":"product_tag-premature-ejaculation","16":"product_tag-sildenafil","17":"product_tag-ssri","19":"first","20":"instock","21":"shipping-taxable","22":"purchasable","23":"product-type-variable","24":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/62135","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=62135"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/62136"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=62135"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=62135"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=62135"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=62135"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}