{"id":64808,"date":"2024-10-29T13:33:06","date_gmt":"2024-10-29T13:33:06","guid":{"rendered":"https:\/\/medsbase.com\/?post_type=product&#038;p=64808"},"modified":"2026-05-10T08:48:12","modified_gmt":"2026-05-10T08:48:12","slug":"nemocid","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/nemocid\/","title":{"rendered":"Nemocid"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"margin:0 0 22px;padding:16px 20px;background:#fff8e1;border-left:4px solid #f5a623;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px;font-size:18px;color:#2c3e50;\">Quick Answer &mdash; What is Nemocid?<\/h3>\n<div style=\"margin:0;font-size:15px;line-height:1.55;color:#333;\">\n<p><strong>Nemocid<\/strong> je peror\u00e1ln\u00ed <strong>pyrantel pamoate 250&nbsp;mg<\/strong> od <strong>Cipla<\/strong>. Pyrantel is the over-the-counter pinworm and roundworm agent in many countries (US, UK Combantrin) and works by depolarising parasite neuromuscular junctions &mdash; the worm is paralysed and passed in stool. Standard adult dose: <strong>11&nbsp;mg\/kg as a single dose (max 1&nbsp;g)<\/strong>, repeated in 2 weeks for pinworm.<\/p>\n<\/div>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"margin:24px 0;padding:14px 18px;background:#f4f4f4;border:1px solid #e1e1e1;border-radius:4px;font-size:14px;color:#444;line-height:1.55;\"><strong>Pro\u010d objedn\u00e1vat z MedsBase:<\/strong> \u2713 Zdrojeno od <strong>WHO-GMP certifikovan\u00fdch v\u00fdrobc\u016f<\/strong> \u00b7 \u2713 Diskr\u00e9tn\u00ed balen\u00ed \u00b7 \u2713 Doprava do cel\u00e9ho sv\u011bta \u00b7 \u2713 <strong>1,400+ recenz\u00ed z\u00e1kazn\u00edk\u016f<\/strong> na <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">medsbase.com\/reviews<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<h3>Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n<h2 class=\"wp-block-heading\">What is Nemocid?<\/h2>\n<p><strong>Nemocid<\/strong> is pyrantel pamoate 250&nbsp;mg from <strong>Cipla<\/strong>. Pyrantel pamoate is a depolarising neuromuscular blocking agent specifically designed for parasites, with negligible absorption from the gut so systemic side effects are uncommon. Available over the counter in many regulated markets, pyrantel is a longstanding alternative to the benzimidazoles (albendazole, mebendazole) for pinworm and roundworm.<\/p>\n<h2 class=\"wp-block-heading\">Mechanismus \u00fa\u010dinku<\/h2>\n<p>Pyrantel pamoate is a <strong>depolarising neuromuscular blocker<\/strong>: it binds nicotinic acetylcholine receptors on parasite muscle, causing sustained depolarisation and spastic paralysis. The paralysed worm releases its grip on the gut wall and is passed in faeces. The mechanism is the opposite of piperazine, which causes flaccid paralysis &mdash; piperazine and pyrantel should not be combined as they antagonise each other.<\/p>\n<p>Less than 15% of an oral dose is absorbed; peak plasma is at 1&ndash;3 hours; both unchanged drug and metabolites are excreted predominantly in faeces. Low systemic exposure means very few off-target effects.<\/p>\n<h2 class=\"wp-block-heading\">Nemocid indications and dose<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;font-size:14px;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Indikace<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">D\u00e1vka<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">D\u00e1vkovac\u00ed sch\u00e9ma<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Pinworm (Enterobius)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">11&nbsp;mg\/kg (max 1&nbsp;g)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Single dose, repeat at 2 weeks<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Roundworm (Ascaris)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">11&nbsp;mg\/kg<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Jednor\u00e1zov\u00e1 d\u00e1vka<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Hookworm (Ancylostoma, Necator)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">11&nbsp;mg\/kg daily<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">For 3 days for heavy infection<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Trichostrongylus<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">11&nbsp;mg\/kg<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Jednor\u00e1zov\u00e1 d\u00e1vka<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Approximate adult dose: 1&ndash;4 tablets depending on body weight (1 tablet = 250&nbsp;mg pyrantel pamoate base). Take with or without food. Most preparations also exist as suspensions for paediatric weight-based dosing &mdash; ask if you need the suspension format.<\/p>\n<h2 class=\"wp-block-heading\">Vedlej\u0161\u00ed \u00fa\u010dinky<\/h2>\n<ul>\n<li><strong>\u010cast\u00e9:<\/strong> mild GI upset, nausea, abdominal cramps, transient diarrhoea<\/li>\n<li><strong>M\u00e9n\u011b \u010dast\u00e9:<\/strong> headache, dizziness, drowsiness, rash, transient transaminase rise<\/li>\n<li><strong>Vz\u00e1cn\u00e9:<\/strong> hepatic dysfunction (limited reports)<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Interakce l\u00e9k\u016f<\/h2>\n<ul>\n<li><strong>Piperazine<\/strong> &mdash; antagonises pyrantel (opposite mechanism); never combine<\/li>\n<li><strong>Theofylin<\/strong> &mdash; pyrantel may modestly raise theophylline levels; monitor in long courses<\/li>\n<li>No clinically significant CYP interactions because systemic exposure is low<\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;line-height:1.55;color:#444;\"><strong>T\u011bhotenstv\u00ed &amp; kojen\u00ed.<\/strong> Albendazol a mebendazol se v prvn\u00edm trimestru NEdoporu\u010duj\u00ed (\u00fadaje o teratogenit\u011b u zv\u00ed\u0159at). Pou\u017eit\u00ed je p\u0159ijateln\u00e9 ve 2. a 3. trimestru p\u0159i st\u0159edn\u00ed a\u017e t\u011b\u017ek\u00e9 helmintick\u00e9 z\u00e1t\u011b\u017ei. \u00dadaje o ivermektinu v t\u011bhotenstv\u00ed jsou omezen\u00e9, ale v programech hromadn\u00e9 l\u00e9\u010dby WHO jsou uklid\u0148uj\u00edc\u00ed; vyhn\u011bte se v prvn\u00edm trimestru, pokud existuj\u00ed alternativy. Praziquantel a pyrantel jsou kompatibiln\u00ed s t\u011bhotenstv\u00edm.<\/div>\n<div style=\"background:#f4f8fb;border-left:4px solid #2c7cb0;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;line-height:1.55;color:#444;\"><strong>Pozn\u00e1mka pro pediatrii.<\/strong> V\u011bt\u0161ina antihelmintik je bezpe\u010dn\u00e1 od v\u011bku 2 let a v\u00fd\u0161e; ivermektin je schv\u00e1len od t\u011blesn\u00e9 hmotnosti 15 kg; albendazol 400 mg v jedn\u00e9 d\u00e1vce je standard WHO od v\u011bku 1 roku v programech hromadn\u00e9 l\u00e9\u010dby. U d\u011bt\u00ed mlad\u0161\u00edch 2 let zvolte pediatrick\u00e9 suspenze a konzultujte klinika pro d\u00e1vkov\u00e1n\u00ed podle hmotnosti.<\/div>\n<h2 class=\"wp-block-heading\">Kontraindikace<\/h2>\n<ul>\n<li>Hypersensitivity to pyrantel pamoate<\/li>\n<li>Children &lt; 2 years (consult paediatrician for off-label use)<\/li>\n<li>V\u00fdznamn\u00e9 po\u0161kozen\u00ed jater<\/li>\n<li>Pregnancy &mdash; first trimester avoidance recommended; later trimesters acceptable for moderate-to-heavy worm burden<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Skladov\u00e1n\u00ed<\/h2>\n<p>Store Nemocid below 25&deg;C, away from light and moisture. Keep out of reach of children.<\/p>\n<h3 class=\"wp-block-heading\">Pro\u010d objedn\u00e1vat z MedsBase<\/h3>\n<p>Nemocid is supplied from a <strong>v\u00fdrobce certifikovan\u00e9ho WHO-GMP<\/strong>, balen diskr\u00e9tn\u011b a expedov\u00e1n po cel\u00e9m sv\u011bt\u011b. Ka\u017ed\u00e1 objedn\u00e1vka je kryta na\u0161\u00edm <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\">Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/a> \u2014 nikdy nenese\u0161 n\u00e1klady za ztracenou z\u00e1silku.<\/p>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3 class=\"wp-block-heading\">Why choose pyrantel over albendazole?<\/h3>\n<p>Pyrantel is over-the-counter in many countries, has a long pregnancy-safety record, has minimal CYP interactions, and almost no systemic exposure. Albendazole and mebendazole work for the same indications and cover whipworm too &mdash; pyrantel does NOT cover whipworm.<\/p>\n<h3 class=\"wp-block-heading\">How quickly does Nemocid work?<\/h3>\n<p>Worms are paralysed within hours and passed in faeces over the next 24&ndash;72 hours. Pinworm symptoms (perianal itching) usually resolve within a week.<\/p>\n<h3 class=\"wp-block-heading\">M\u00e1m l\u00e9\u010dit i ostatn\u00ed \u010dleny rodiny?<\/h3>\n<p>Yes for pinworm. Treat all household members on the same day and repeat in 2 weeks. Otherwise reinfection is almost guaranteed.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Nemocid with food?<\/h3>\n<p>Yes &mdash; food does not impair efficacy because pyrantel works in the gut lumen.<\/p>\n<h3 class=\"wp-block-heading\">Does Nemocid treat tapeworm?<\/h3>\n<p>No. Pyrantel is active against nematodes (roundworms) only &mdash; not tapeworm and not flukes. Use niclosamide or praziquantel for tapeworm.<\/p>\n<h3 class=\"wp-block-heading\">Is Nemocid safe in pregnancy?<\/h3>\n<p>Pyrantel has one of the better pregnancy-safety records among anthelmintics. The first trimester is still typically avoided where possible. Discuss with a clinician.<\/p>\n<h3 class=\"wp-block-heading\">What about whipworm?<\/h3>\n<p>Pyrantel does NOT treat whipworm reliably. For whipworm use albendazole 400 mg daily for 3 days.<\/p>\n<h3 class=\"wp-block-heading\">How does pyrantel compare to mebendazole?<\/h3>\n<p>Both are first-line over-the-counter pinworm\/roundworm agents. Mebendazole also covers whipworm; pyrantel does not. Mebendazole is a benzimidazole; pyrantel is a depolarising blocker. Cross-resistance is uncommon.<\/p>\n<h3 class=\"wp-block-heading\">What if I miss the second dose?<\/h3>\n<p>Take it as soon as you remember. The 2-week timing exists to catch the next pinworm life cycle &mdash; if you delay by a few days the protocol still works, but a longer gap risks reinfection.<\/p>\n<p class=\"medsbase-link-boost-2026-05-07\" data-marker=\"mb-link-boost-wormentel\">Zat\u00edmco <a href=\"\/cs\/nemocid\/\">Nemocid<\/a> (pyrantel pamoate 250&nbsp;mg) targets pinworm and roundworm via a neuromuscular mechanism, <a href=\"\/cs\/wormentel\/\">Wormentel (fenbendazole 222&nbsp;\/&nbsp;500&nbsp;mg)<\/a> provides a complementary benzimidazole option covering Giardia and tapeworms for cases where pyrantel alone may be insufficient.<\/p>\n<p class=\"medsbase-link-boost-2026-05-10\" data-marker=\"mb-link-boost-iverheal\">Patients taking <a href=\"https:\/\/medsbase.com\/cs\/nemocid\/\">Nemocid (pyrantel pamoate 250 mg)<\/a> for pinworm or roundworm infection who subsequently test positive for strongyloidiasis are typically transitioned to <a href=\"https:\/\/medsbase.com\/cs\/iverheal\/\">Iverheal (ivermectin 3 \/ 6 \/ 12 mg)<\/a>, which acts by a distinct neuronal mechanism on susceptible nematode species.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Dal\u0161\u00ed antiparazit\u00e1rn\u00ed l\u00e9ky<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/cs\/nemocid\/\">Nemocid (pyrantel pamoate 250 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/abd-400-albendazole\/\">ABD 400 (albendazol 400 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/mebex\/\">Mebex (mebendazol 100 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/iverheal\/\">Iverheal (ivermectin)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/cs\/bendex-suspension\/\">Bendex Suspension (d\u011btsk\u00fd albendazol)<\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:22px 0;border-radius:4px;font-size:14px;color:#444;\"><strong>Zdravotn\u00ed prohl\u00e1\u0161en\u00ed.<\/strong> Tato str\u00e1nka slou\u017e\u00ed pouze pro vzd\u011bl\u00e1vac\u00ed \u00fa\u010dely a nenahrazuje odborn\u00e9 l\u00e9ka\u0159sk\u00e9 poradenstv\u00ed. P\u0159ed zah\u00e1jen\u00edm jak\u00e9koli l\u00e9\u010dby proti parazit\u016fm se pora\u010fte s kvalifikovan\u00fdm l\u00e9ka\u0159em, zejm\u00e9na pokud jste t\u011bhotn\u00e1 nebo koj\u00edte, m\u00e1te oslabenou imunitu, l\u00e9\u010d\u00edte d\u00edt\u011b mlad\u0161\u00ed 2 let, nebo pokud p\u0159\u00edznaky p\u0159etrv\u00e1vaj\u00ed po ukon\u010den\u00ed l\u00e9\u010dby. Eozinofilie, \u00fabytek hmotnosti, p\u0159etrv\u00e1vaj\u00edc\u00ed bolesti b\u0159icha nebo p\u0159\u00edznaky spojen\u00e9 s cestov\u00e1n\u00edm vy\u017eaduj\u00ed klinick\u00e9 vy\u0161et\u0159en\u00ed. Z\u00e1va\u017en\u00e1 parazit\u00e1rn\u00ed onemocn\u011bn\u00ed (neurocysticerk\u00f3za, hyperinfekce strongyloidy, schistosom\u00f3za s posti\u017een\u00edm org\u00e1n\u016f) vy\u017eaduj\u00ed specializovanou p\u00e9\u010di.<\/div>","protected":false},"excerpt":{"rendered":"<p>Nemocid (pyrantel pamoate 250 mg, Cipla) \u2014 depolarising-blocker anthelmintic for pinworm, roundworm, and hookworm. Pregnancy-acceptable single-dose 11 mg\/kg therapy with minimal systemic exposure.<\/p>","protected":false},"featured_media":64810,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[3856],"product_tag":[5318,5319],"class_list":{"0":"post-64808","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-threadworm-treatment","7":"product_tag-nemocid","8":"product_tag-pyrantel-pamoate","10":"first","11":"instock","12":"shipping-taxable","13":"purchasable","14":"product-type-variable","15":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/64808","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=64808"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/64810"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=64808"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=64808"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=64808"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=64808"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}