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Wormentel<\/strong> obsahuje fenbendazole<\/strong>, a benzimidazole-class broad-spectrum antiparasitic with over 50 years of clinical use in veterinary medicine and emerging use as a human anthelmintic in jurisdictions where albendazole or mebendazole are not available. Available at MedsBase in 222 mg, 444 mg and 500 mg tablets<\/strong>. Fenbendazole is highly effective against intestinal nematodes (roundworms, hookworms, whipworms), cestodes (tapeworms), and several protozoal parasites including Giardia<\/em>. Standard human dewormer protocols use 222-500 mg once daily for 3 consecutive days<\/strong>, with a repeat course at 14 days for pinworm\/threadworm cycles. Fenbendazole has an excellent safety profile — absorption is low, side effects are uncommon and usually mild gastrointestinal. Not for use in pregnancy<\/strong> (benzimidazole class effect — teratogenic in animal studies at high doses).<\/p>\n<\/div>\n \ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n Na\u0161e generick\u00e9 l\u00e9ky poch\u00e1zej\u00ed od v\u00fdrobc\u016f certifikovan\u00fdch WHO-GMP a jsou expedov\u00e1ny po cel\u00e9m sv\u011bt\u011b v diskr\u00e9tn\u00edm, nen\u00e1padn\u00e9m balen\u00ed \u2013 na vn\u011bj\u0161\u00ed stran\u011b bal\u00edku nen\u00ed uveden n\u00e1zev l\u00e9ku. Platby kartou jsou sm\u011brov\u00e1ny prost\u0159ednictv\u00edm regulovan\u00e9ho procesoru (popisky na v\u00fdpisu zahrnuj\u00ed regulovan\u00e9ho procesora plateb kartou \u2013 nikdy \u201cMedsBase\u201d nebo n\u00e1zev l\u00e9ku). P\u0159ij\u00edm\u00e1me tak\u00e9 kryptom\u011bny a bankovn\u00ed p\u0159evody SEPA. Ka\u017ed\u00e1 objedn\u00e1vka je zaji\u0161t\u011bna na\u0161\u00ed politikou p\u0159eposl\u00e1n\u00ed.<\/p>\n Wormentel is a brand of fenbendazole<\/strong>, a benzimidazole-class broad-spectrum anthelmintic (antiparasitic) drug. It is supplied in three tablet strengths: 222 mg, 444 mg and 500 mg<\/strong>. The 222 mg and 444 mg strengths use the same dosing units as the original veterinary product (Panacur), allowing flexible dosing across the wide range of indications and species; the 500 mg strength is convenient for adult human dosing.<\/p>\n Fenbendazole has been in continuous clinical use since the 1970s — primarily as a veterinary anthelmintic in dogs, cats, horses, cattle, sheep, goats, pigs, and zoo animals (where it is one of the most widely used dewormers globally). It is increasingly used in humans in jurisdictions where albendazole or mebendazole supply is intermittent.<\/p>\n Pack sizes available at MedsBase: 30, 60, 90, 200, 400 nebo 800 tablet<\/strong>.<\/p>\n Regulatory status note:<\/strong> Fenbendazole is not currently licensed for human use in the EU, UK, USA or Australia — albendazole (Zentel) and mebendazole (Vermox) are the licensed benzimidazoles for humans in those jurisdictions. Off-label and over-the-counter human use of fenbendazole is widespread in parts of Asia, South America, and the Indian subcontinent, where the drug has been used safely in human populations for decades.<\/p>\n Fenbendazole binds with high affinity to parasite β-tubulin<\/strong>, blocking microtubule polymerisation in the parasite’s cells. This disrupts the parasite’s ability to absorb glucose from the host gut, causes energy depletion within 24-48 hours, and ultimately kills the parasite. Mammalian (host) tubulin has a much lower affinity for benzimidazoles, which is why these drugs are highly selective and well-tolerated in humans and animals.<\/p>\n Fenbendazole is poorly absorbed from the gastrointestinal tract — oral bioavailability is approximately 1-2% in dogs and humans. This is actually advantageous for an intestinal anthelmintic: high concentrations are maintained in the gut lumen (where the parasites live) while systemic exposure stays low. Taking fenbendazole with a fatty meal increases absorption modestly.<\/p>\n The drug is metabolised in the liver to oxfendazole (the sulfoxide) and a sulfone metabolite, both of which retain anthelmintic activity. Excretion is primarily faecal.<\/p>\n Established indications:<\/strong><\/p>\n Veterinary indications<\/strong> (Wormentel is also used by vets and pet owners worldwide):<\/p>\n Adult human dosing (off-label, follow medical advice):<\/strong><\/p>\nPro\u010d objedn\u00e1vat z MedsBase<\/h3>\n
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What is Wormentel?<\/h2>\n
How fenbendazole works<\/h2>\n
Which parasites Wormentel treats<\/h2>\n
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Dosage by indication & strength<\/h2>\n