{"id":68758,"date":"2026-02-21T13:56:34","date_gmt":"2026-02-21T13:56:34","guid":{"rendered":"https:\/\/medsbase.com\/?post_type=product&#038;p=68758"},"modified":"2026-05-21T07:14:12","modified_gmt":"2026-05-21T07:14:12","slug":"tb-500","status":"publish","type":"product","link":"https:\/\/medsbase.com\/cs\/product\/tb-500\/","title":{"rendered":"TB-500 (Thymosin Beta-4)"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background: #fff8e1; border-left: 4px solid #f5a623; padding: 18px 22px; margin: 18px 0; border-radius: 4px;\">\n<h3 style=\"margin: 0 0 8px 0; font-size: 16px; color: #1a4a6b;\">Quick Answer \u2014 What is TB-500?<\/h3>\n<p style=\"margin: 0;\"><strong>TB-500<\/strong> is a synthetic analog of <strong>Thymosin Beta-4<\/strong>, a naturally occurring 43-amino-acid peptide with systemic healing activity. In published preclinical research it binds G-actin, stimulates angiogenesis via the VEGF\/KDR pathway, and modulates TGF-beta inflammatory signaling. Supplied in 2\u00a0mg to 10\u00a0mg lyophilized vials for laboratory research use only.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background: #f4f8fb; border: 1px solid #d8e3eb; padding: 12px 16px; margin: 16px 0; border-radius: 4px; font-size: 14px;\"><strong>Co z\u00edsk\u00e1te s MedsBase:<\/strong> V\u00fdzkumn\u00e9 lyofilizovan\u00e9 peptidy \u00b7 HPLC \u010distota \u226599% (COA na vy\u017e\u00e1d\u00e1n\u00ed) \u00b7 Diskr\u00e9tn\u00ed teplotn\u011b stabiln\u00ed balen\u00ed \u00b7 Celosv\u011btov\u00e1 p\u0159eprava peptid\u016f \u00b7 1,400+ ov\u011b\u0159en\u00fdch <a href=\"https:\/\/medsbase.com\/cs\/reviews\/\">recenz\u00ed z\u00e1kazn\u00edk\u016f<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size: 14px; color: #444; margin: 8px 0 18px;\">\ud83d\udce6 Ka\u017ed\u00e1 objedn\u00e1vka je pokryta na\u0161\u00ed <a href=\"https:\/\/medsbase.com\/cs\/medsbase-re-shipment-assurance-policy\/\"><strong>Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/strong><\/a> \u2014 pokud va\u0161e z\u00e1silka nedoraz\u00ed do 20 pracovn\u00edch dn\u016f, p\u0159epos\u00edl\u00e1me ji.<\/p>\n<table class=\"medsbase-spec-table\" style=\"width: 100%; border-collapse: collapse; margin: 18px 0; font-size: 14px;\">\n<thead>\n<tr style=\"background: #2c7cb0; color: #fff;\">\n<th style=\"padding: 8px 12px; text-align: left; width: 30%;\">Specifikace<\/th>\n<th style=\"padding: 8px 12px; text-align: left;\">Detail<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>CAS \u010d\u00edslo<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">77591-33-4<\/td>\n<\/tr>\n<tr style=\"background: #fff;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>item2<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">C<sub>212<\/sub>H<sub>350<\/sub>N<sub>56<\/sub>O<sub>78<\/sub>S<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>item7<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">~4963 Da (N-acetyl Thymosin \u03b2-4 (1\u201343))<\/td>\n<\/tr>\n<tr style=\"background: #fff;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>item9<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>item11<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">item12<\/td>\n<\/tr>\n<tr style=\"background: #fff;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>item13<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">\u226599% (HPLC ov\u011b\u0159eno, COA na vy\u017e\u00e1d\u00e1n\u00ed)<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>Skladov\u00e1n\u00ed<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">Lyophilized: 2\u20138\u00a0\u00b0C (refrigerator) for working stock; \u221220\u00a0\u00b0C for long-term storage of unopened vials. Reconstituted: 2\u20138\u00a0\u00b0C, use within ~30 days. Avoid vigorous agitation; large peptides denature with shaking. Do not freeze\u2013thaw the reconstituted solution.<\/td>\n<\/tr>\n<tr style=\"background: #fff;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>Rozpustnost<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">Bakteriostatick\u00e1 voda (doporu\u010deno) nebo steriln\u00ed voda pro krat\u0161\u00ed dobu pou\u017eit\u00ed<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>Pouze pro v\u00fdzkum<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">Pouze pro laboratorn\u00ed v\u00fdzkum. Nen\u00ed ur\u010deno pro diagnostick\u00e9 nebo terapeutick\u00e9 pou\u017eit\u00ed u lid\u00ed nebo zv\u00ed\u0159at.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><!-- \/medsbase-tldr-answer --><\/p>\n<h2>What Is TB-500?<\/h2>\n<p><strong>TB-500<\/strong> is the laboratory designation for a synthetic analog of <strong>Thymosin Beta-4 (TB4)<\/strong>, a naturally-occurring 43-amino-acid peptide hormone found in nearly every cell of the human body. TB4 is most abundant in platelets, and is released at sites of tissue damage where it orchestrates cell migration, angiogenesis, and anti-inflammatory signaling. The synthetic research form \u2014 TB-500 \u2014 reproduces the biological activity of TB4 and is the most widely studied research compound in this class.<\/p>\n<p>The TB4 sequence is <em>Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES<\/em>, molecular weight approximately 4,963\u00a0Da. It is supplied as a high-purity lyophilized powder for reconstitution with bacteriostatic water. TB-500 is <strong>ur\u010den pouze pro laboratorn\u00ed v\u00fdzkum<\/strong> and is not intended for human or veterinary diagnosis or therapy. For mechanism, published trial detail, and research-dosing considerations, see our full <a href=\"https:\/\/medsbase.com\/cs\/tb-500-thymosin-beta-4-peptide-guide\/\">TB-500 research guide<\/a>.<\/p>\n<h2>Mechanism of Action \u2014 Systemic Healing via Three Pathways<\/h2>\n<p>TB-500 is distinguished from most peptides by its <strong>systemic distribution and long circulating half-life<\/strong>, which allow a single administration to influence repair processes across multiple tissues simultaneously. The three primary mechanistic pathways in published research:<\/p>\n<ul>\n<li><strong>G-actin sequestration<\/strong> \u2014 TB-500 binds monomeric actin (G-actin) via a central actin-binding motif (LKKTETQ). This preserves the cytoskeletal reservoir cells need to extend pseudopodia, migrate toward injury sites, and remodel after damage. Cell-migration assays in wound-edge research consistently show enhanced migration rates in TB4-treated cells.<\/li>\n<li><strong>Angiogenesis via VEGF \/ KDR signaling<\/strong> \u2014 TB-500 stimulates vascular endothelial migration and capillary formation through the VEGF receptor 2 (KDR) pathway. In ischemia-reperfusion and wound-healing research this translates to faster restoration of perfusion at repair sites.<\/li>\n<li><strong>Anti-inflammatory signaling via TGF-beta modulation<\/strong> \u2014 TB-500 reduces pro-inflammatory cytokine release and accelerates resolution of the inflammatory phase of healing. In cardiac ischemia research, this has been linked to reduced infarct size and preserved cardiomyocyte function.<\/li>\n<\/ul>\n<p>Because these three mechanisms distribute throughout the body, TB-500 produces effects in tissues distant from the injection site \u2014 the hallmark that distinguishes it from more localized healing peptides such as <a href=\"https:\/\/medsbase.com\/cs\/bpc-157\/\">BPC-157<\/a>. The practical consequence: TB-500 research protocols are dosed twice weekly rather than daily.<\/p>\n<h2>Publikovan\u00e9 v\u00fdzkumn\u00e9 aplikace<\/h2>\n<p>TB-500 is used in laboratory research contexts that investigate:<\/p>\n<ul>\n<li><strong>Skeletal muscle repair<\/strong> \u2014 systemic recovery kinetics in crush, strain, and disuse-atrophy rodent models<\/li>\n<li><strong>Cardiac recovery research<\/strong> \u2014 cardiomyocyte survival, infarct size, and vascular remodeling post-ischemia (Smart et al., Nature 2011; Bock-Marquette et al., Nature 2004)<\/li>\n<li><strong>Tendon and ligament healing<\/strong> \u2014 alone or stacked with <a href=\"https:\/\/medsbase.com\/cs\/bpc-157\/\">BPC-157<\/a> in connective-tissue repair research<\/li>\n<li><strong>Systemic wound repair<\/strong> \u2014 dermal and corneal wound-healing research, especially where multiple tissue beds are affected<\/li>\n<li><strong>Hair cycle research<\/strong> \u2014 follicular angiogenesis and hair-growth phase transitions in rodent research models<\/li>\n<li><strong>Vascular repair<\/strong> \u2014 endothelial cell migration, capillary formation, and ischemia research<\/li>\n<li><strong>Comparative peptide research<\/strong> \u2014 benchmarking against BPC-157 as the canonical local-healing comparator, or with <a href=\"https:\/\/medsbase.com\/cs\/igf-1-lr3-peptide-guide\/\">IGF-1 LR3<\/a> a <a href=\"https:\/\/medsbase.com\/cs\/ipamorelin-cjc-1295-stack-guide\/\">Ipamorelin\/CJC-1295<\/a> in growth-factor research. See our <a href=\"https:\/\/medsbase.com\/cs\/bpc-157-vs-tb-500-comparison-guide\/\">srovn\u00e1n\u00ed BPC-157 vs TB-500<\/a> for the side-by-side.<\/li>\n<\/ul>\n<p>For broader context on where TB-500 fits within the healing-peptide landscape, see <a href=\"https:\/\/medsbase.com\/cs\/best-peptides-for-muscle-recovery\/\">the best peptides for muscle recovery<\/a> cluster article and complementary research compounds in the <a href=\"https:\/\/medsbase.com\/cs\/peptides\/\">peptides catalog<\/a>.<\/p>\n<h2>Dostupn\u00e9 s\u00edly a koncentrace<\/h2>\n<p>MedsBase stocks TB-500 (synthetic Thymosin Beta-4) in the following lyophilized vial sizes. Each variation ships in 10-vial, 20-vial, or 30-vial pack formats with full reconstitution guidance:<\/p>\n<table style=\"width: 100%; border-collapse: collapse; margin: 16px 0;\">\n<thead>\n<tr style=\"background: #2c7cb0; color: #fff;\">\n<th style=\"padding: 10px; border: 1px solid #ddd; text-align: left;\">S\u00edla vialky<\/th>\n<th style=\"padding: 10px; border: 1px solid #ddd; text-align: left;\">Typick\u00e9 pou\u017eit\u00ed<\/th>\n<th style=\"padding: 10px; border: 1px solid #ddd; text-align: left;\">Velikosti balen\u00ed<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>2\u00a0mg<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">Pilot research, titration, or short protocols<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">10, 20, or 30 vials<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>5 mg<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">Standard research strength, matches common 2\u20132.5\u00a0mg dose-per-administration protocols<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">10, 20, or 30 vials<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>10 mg<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">Extended research, bulk prep, lowest per-mg cost<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">10, 20, or 30 vials<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>All three strengths are the same chemical form (lyophilized powder, 99%+ HPLC purity). Higher-mg vials offer lower per-mg cost and are generally preferred when researchers are modeling the 2\u20132.5\u00a0mg per-administration dose used across most published TB-500 protocols.<\/p>\n<h2>How It Compares \u2014 TB-500 vs BPC-157<\/h2>\n<p>TB-500 and <a href=\"https:\/\/medsbase.com\/cs\/bpc-157\/\">BPC-157<\/a> are the two most-cited healing-research peptides. They are often studied together because their mechanisms are complementary rather than overlapping \u2014 BPC-157 acts locally via growth-factor upregulation, TB-500 acts systemically via actin and angiogenesis pathways.<\/p>\n<table style=\"width: 100%; border-collapse: collapse; margin: 16px 0;\">\n<thead>\n<tr style=\"background: #2c7cb0; color: #fff;\">\n<th style=\"padding: 10px; border: 1px solid #ddd; text-align: left;\">Krit\u00e9rium<\/th>\n<th style=\"padding: 10px; border: 1px solid #ddd; text-align: left;\">TB-500 (Thymosin Beta-4)<\/th>\n<th style=\"padding: 10px; border: 1px solid #ddd; text-align: left;\">BPC-157<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>Length<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">43 amino acids (~4,963\u00a0Da)<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">15 amino acids (~1,419\u00a0Da)<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>Primary mechanism<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">G-actin sequestration, angiogenesis, TGF-beta<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">VEGF + NO + GH receptor upregulation<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>Distribution<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">Systemic, distributes widely<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">More localized at injection site<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>Typical research dose<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">2\u20132.5\u00a0mg twice weekly, 4\u20136 week loading<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">250\u2013500\u00a0mcg, 1\u20132x daily<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>Nejsiln\u011bj\u0161\u00ed v\u00fdzkumn\u00fd sign\u00e1l<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">Cardiac, systemic muscle, vascular, hair<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">Tendon, ligament, gut barrier<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>Stacking<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">Commonly co-administered with BPC-157<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">Commonly co-administered with TB-500<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>For the full side-by-side methodological comparison and when researchers pick one over the other, read <a href=\"https:\/\/medsbase.com\/cs\/bpc-157-vs-tb-500-comparison-guide\/\">BPC-157 vs TB-500: which healing peptide for your recovery goal<\/a>.<\/p>\n<h2>Skladov\u00e1n\u00ed a rekonstituce<\/h2>\n<p><strong>P\u0159ed rekonstituci:<\/strong> store lyophilized vials refrigerated at 2\u20138\u00a0\u00b0C in original packaging. Lyophilized TB-500 is stable under these conditions for up to 36 months. Avoid freeze-thaw cycles on the powder.<\/p>\n<p><strong>Postup rekonstituce:<\/strong> inject bacteriostatic water down the side wall of the peptide vial (not directly onto the lyophilized cake) per the dilution table above. Swirl gently \u2014 do <strong>ne<\/strong> shake \u2014 and allow 5\u201310 minutes for full dissolution. A correctly reconstituted solution should be clear and colourless.<\/p>\n<p><strong>Po rekonstituci:<\/strong> store refrigerated at 2\u20138\u00a0\u00b0C and use within 30 days for optimal stability. Do not freeze reconstituted solution \u2014 freeze-thaw cycles degrade peptide integrity. Discard any vial showing cloudiness, precipitate, or discolouration.<\/p>\n<h2 id=\"faqs\">\u010casto kladen\u00e9 dotazy<\/h2>\n<h3>What is TB-500 used for in research?<\/h3>\n<p>TB-500 is used in laboratory research investigating skeletal muscle repair, cardiac recovery, tendon and ligament healing, wound repair, hair-cycle research, vascular repair, and systemic tissue regeneration. It is <strong>ne<\/strong> FDA-approved and is sold here strictly for laboratory research use only.<\/p>\n<h3>How is TB-500 different from BPC-157?<\/h3>\n<p>TB-500 is a 43-amino-acid synthetic analog of Thymosin Beta-4 that acts systemically via G-actin binding, angiogenesis, and TGF-beta signaling. BPC-157 is a 15-amino-acid pentadecapeptide that acts mostly locally via VEGF, nitric oxide, and growth-hormone-receptor pathways. The two are often co-administered in research because their mechanisms are complementary.<\/p>\n<h3>What is the typical TB-500 research dose?<\/h3>\n<p>Published preclinical protocols typically use 2\u20132.5\u00a0mg per administration, given twice weekly for a 4\u20136 week loading phase followed by a weekly maintenance phase. A 5\u00a0mg vial reconstituted with 2.0\u00a0mL bacteriostatic water yields 2.5\u00a0mg\/mL \u2014 80 ticks on a U-100 syringe delivers 2\u00a0mg.<\/p>\n<h3>Is TB-500 FDA approved?<\/h3>\n<p>No. TB-500 (synthetic Thymosin Beta-4) is not approved by the FDA, EMA, MHRA, or any other regulator for human therapeutic use. All TB-500 sold by research-use-only suppliers is for laboratory investigation and should not be administered to humans.<\/p>\n<h3>How should TB-500 be stored?<\/h3>\n<p>Lyofilizovan\u00e9 vialky: skladujte v chladni\u010dce p\u0159i 2\u20138 \u00b0C v p\u016fvodn\u00edm obalu, stabilita a\u017e 36 m\u011bs\u00edc\u016f. P\u0159ipraven\u00fd roztok: skladujte v chladni\u010dce p\u0159i 2\u20138 \u00b0C, pou\u017eijte do 30 dn\u016f. P\u0159ipraven\u00fd roztok nezmrazujte \u2014 mrazic\u00ed cykly peptid degraduj\u00ed.<\/p>\n<h3>How do I reconstitute TB-500?<\/h3>\n<p>Follow the reconstitution reference chart above. Add bacteriostatic water down the side wall of the vial (not onto the lyophilized cake), swirl gently, and allow 5\u201310 minutes for full dissolution. Do <strong>ne<\/strong> shake the vial.<\/p>\n<h3>Jak\u00e9 s\u00edly nab\u00edz\u00ed MedsBase?<\/h3>\n<p>MedsBase carries TB-500 in 2\u00a0mg, 5\u00a0mg, and 10\u00a0mg lyophilized vials. Each strength is available in 10-vial, 20-vial, or 30-vial pack sizes. All vials are supplied at 99%+ HPLC purity with a certificate of analysis available on request.<\/p>\n<h3>Can TB-500 and BPC-157 be stacked in research?<\/h3>\n<p>Yes. TB-500 and BPC-157 are among the most commonly co-administered peptides in preclinical research. Their mechanisms are complementary (systemic vs local, actin-binding vs growth-factor-upregulation), and combined protocols appear frequently in connective-tissue and muscle-recovery research. See our <a href=\"https:\/\/medsbase.com\/cs\/bpc-157-vs-tb-500-comparison-guide\/\">comparison guide<\/a>.<\/p>\n<h3>Why is TB-500 dosed less often than BPC-157?<\/h3>\n<p>TB-500 has a longer circulating half-life and distributes systemically, so published research protocols typically dose twice weekly. BPC-157 is more localized and commonly dosed once or twice daily in the same types of injury-model research.<\/p>\n<h3>Does TB-500 cause side effects in research?<\/h3>\n<p>Published preclinical research has reported a reasonable safety profile at typical research doses. Long-term human safety data are not available because TB-500 has not been approved for human use and is sold for research only. Published toxicology work has not identified off-target signals at standard research doses.<\/p>\n<h3>Is TB-500 the same as full Thymosin Beta-4?<\/h3>\n<p>TB-500 is marketed as a synthetic form of Thymosin Beta-4 (TB4). In commercial research-use-only supply, what is sold as &#8220;TB-500&#8221; is typically the full 43-amino-acid TB4 molecule synthesized chemically. Some literature refers to shorter actin-binding fragments (LKKTETQ) as functional TB4 analogs in narrow research contexts, but full-length TB4 is the dominant research form.<\/p>\n<h3>What is the half-life of TB-500?<\/h3>\n<p>TB-500 (synthetic Thymosin Beta-4) has an estimated serum half-life of several days in preclinical research \u2014 significantly longer than most GHRPs and site-specific healing peptides such as BPC-157. This extended half-life supports the less-frequent dosing schedules typically used in T\u03b24 research protocols.<\/p>\n<h3>How long does TB-500 take to show effects in preclinical research?<\/h3>\n<p>Preclinical studies using Thymosin Beta-4 in cardiac, skeletal muscle, and connective tissue models typically observe measurable effects over 2\u20134 week research cycles. The systemic distribution and longer half-life compared to site-directed peptides mean TB-500 research timelines are generally extended.<\/p>\n<h3>Can I order TB-500 for international shipping?<\/h3>\n<p>Yes. MedsBase ships TB-500 worldwide from our dedicated peptide shipping network. Peptide-only orders qualify for our standalone peptide shipping service. All orders ship in temperature-controlled packaging with full tracking.<\/p>\n<p class=\"medsbase-bundle-link-2026-05-01\" data-marker=\"mb-bundle-link-peptide-healing-stack\">TB-500 is most often run alongside BPC-157 \u2014 angiogenesis (BPC-157) plus cytoskeletal repair (TB-500) gives faster, more complete soft-tissue recovery than either peptide alone; our <a href=\"\/cs\/peptide-healing-stack\/\">Peptide Healing Stack (BPC-157 5 mg + TB-500 5 mg + bakteriostatick\u00e1 voda)<\/a> ships the matched protocol in a single parcel.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h2>Dal\u0161\u00ed peptidy pro v\u00fdzkum regenerace a v\u00fdkonnosti<\/h2>\n<ul>\n<li><a href=\"\/cs\/bpc-157\/\"><strong>BPC-157<\/strong><\/a> \u2014 Body Protection Compound \u2014 v\u00fdzkum regenerace \u0161lach, vaz\u016f a st\u0159ev<\/li>\n<li><a href=\"\/cs\/ipamorelin\/\"><strong>Ipamorelin<\/strong><\/a> \u2014 Selektivn\u00ed agonista ghrelinu \u2014 \u010dist\u00fd pulz r\u016fstov\u00e9ho hormonu bez kortizolu\/prolaktinu<\/li>\n<li><a href=\"\/cs\/cjc-1295-with-dac\/\"><strong>CJC-1295 with DAC<\/strong><\/a> \u2014 Analog GHRH s prodlou\u017een\u00fdm polo\u010dasem<\/li>\n<li><a href=\"\/cs\/ghk-cu\/\"><strong>GHK-Cu<\/strong><\/a> \u2014 M\u011b\u010fn\u00fd peptid \u2014 v\u00fdzkum regenerace k\u016f\u017ee a pojivov\u00e9 tk\u00e1n\u011b<\/li>\n<li><a href=\"\/cs\/igf-1-lr3\/\"><strong>IGF-1 LR3<\/strong><\/a> \u2014 Long-R3 IGF-1 analog \u2014 anabolic \/ regenerative research<\/li>\n<\/ul>\n<p><!-- medsbase-peptide-guide-cta --><\/p>\n<h2>Dal\u0161\u00ed \u010dten\u00ed<\/h2>\n<div style=\"background: #f4f8fb; border-left: 4px solid #2c7cb0; padding: 18px 22px; margin: 18px 0; border-radius: 4px;\">\n<p style=\"margin: 0 0 8px 0;\"><strong>\ud83d\udcd6 Seznamte se s v\u00fdzkumem tohoto peptidu<\/strong><\/p>\n<p style=\"margin: 0;\">P\u0159e\u010dt\u011bte si n\u00e1\u0161 kompletn\u00ed pr\u016fvodce zalo\u017een\u00fd na d\u016fkazech: <a href=\"https:\/\/medsbase.com\/cs\/tb-500-thymosin-beta-4-peptide-guide\/\"><strong>TB-500 \u2014 mechanism, trial data &amp; outlook<\/strong><\/a>. Pokr\u00fdv\u00e1 mechanismus \u00fa\u010dinku, publikovan\u00e1 v\u00fdzkumn\u00e1 data, obvykl\u00e9 rozsahy v\u00fdzkumn\u00e9ho d\u00e1vkov\u00e1n\u00ed, protokoly pro rekonstituci, mo\u017enosti kombinace a pozn\u00e1mky k bezpe\u010dnosti\/kontraindikac\u00edm.<\/p>\n<\/div>\n<p><!-- pep-seo-v1 --><\/p>","protected":false},"excerpt":{"rendered":"<p>\u2705 Supports cellular regeneration<br \/>\n\u2705 Enhances tissue modeling<br \/>\n\u2705 Promotes fibroblast activity<br \/>\n\u2705 Stimulates angiogenic signaling<br \/>\n\u2705 Improves extracellular matrix stability<\/p>\n<p><strong>TB-500<\/strong> obsahuje syntetickou peptidovou slou\u010deninu.<\/p>","protected":false},"featured_media":70987,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[5426],"product_tag":[5441,5442,5443],"class_list":{"0":"post-68758","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptides","7":"product_tag-peptide","8":"product_tag-tb-500","9":"product_tag-thymosin-beta-4","11":"first","12":"instock","13":"shipping-taxable","14":"purchasable","15":"product-type-variable","16":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product\/68758","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/comments?post=68758"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media\/70987"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/media?parent=68758"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_brand?post=68758"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat?post=68758"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_tag?post=68758"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}