{"id":3602,"count":10,"description":"The combined oral contraceptive pill (\"the Pill\") and progestogen-only pill (\"mini-pill\") remain the most-used reversible contraception worldwide. The MedsBase Contraceptive Pill catalogue stocks the major COCP and POP brands by progestogen type. (Browse our Alternativn\u00ed antikoncepce<\/a> pro nouzovou antikoncepci a alternativy zna\u010dek.) V\u0161echny produkty jsou dod\u00e1v\u00e1ny spole\u010dnost\u00ed WHO-GMP certifikovan\u00fdch v\u00fdrobc\u016f<\/strong>.\n\nCOCP na b\u00e1zi Levonorgestrelu.<\/strong> Nej\u010dast\u011bji p\u0159edepisovan\u00fd a nejl\u00e9pe prostudovan\u00fd progestogen pro kombinovanou hormon\u00e1ln\u00ed antikoncepci (COCP) \u2014 m\u00edrn\u011b vy\u0161\u0161\u00ed androgenn\u00ed vedlej\u0161\u00ed \u00fa\u010dinky (lehk\u00e9 akn\u00e9 \/ mastn\u00e1 ple\u0165 u n\u011bkter\u00fdch u\u017eivatelek), ale nej\u010dist\u011bj\u0161\u00ed kardiovaskul\u00e1rn\u00ed bezpe\u010dnostn\u00ed profil a nejni\u017e\u0161\u00ed v\u00fdskyt \u017eiln\u00ed tromboembolie (VTE) ve t\u0159\u00edd\u011b COCP. Nab\u00edzen\u00e9 zna\u010dky: Loette<\/a> (etinylestradiol 20 mcg + levonorgestrel 100 mcg \u2014 modern\u00ed d\u00e1vka s nejni\u017e\u0161\u00edm obsahem estrogenu, vhodn\u00e1 pro star\u0161\u00ed u\u017eivatelky nebo ty s rizikem VTE), Ovral-L<\/a> (EE 30 mcg + LNG 150 mcg \u2014 st\u0159edn\u00ed d\u00e1vka, nej\u010dast\u011bji p\u0159edepisovan\u00e1), Ovral G<\/a> (EE 50 mcg + LNG 250 mcg \u2014 star\u0161\u00ed vy\u0161\u0161\u00ed d\u00e1vka pro dohn\u00e1n\u00ed vynechan\u00fdch tablet nebo vybran\u00e9 indikace), Duoluton L<\/a> (alternativn\u00ed n\u00edzk\u00e1 d\u00e1vka), a t\u0159\u00edf\u00e1zov\u00fd Triquilar<\/a> (21denn\u00ed balen\u00ed s prom\u011bnlivou d\u00e1vkou napodobuj\u00edc\u00ed p\u0159irozen\u00fd cyklus).\n\nCOCP na b\u00e1zi drospirenonu.<\/strong> Drospirenon je progestogen odvozen\u00fd od spironolaktonu s anti-mineralokortikoidn\u00ed a anti-androgenn\u00ed aktivitou \u2014 vhodn\u00fd pro \u017eeny s PMS, m\u00edrn\u00fdm nad\u00fdm\u00e1n\u00edm nebo akn\u00e9, ale m\u00e1 m\u00edrn\u011b vy\u0161\u0161\u00ed v\u00fdskyt VTE ne\u017e COCP s levonorgestrelem. Nab\u00edz\u00edme jako Yaz<\/a> (24denn\u00ed aktivn\u00ed tablety + 4denn\u00ed placebo pro krat\u0161\u00ed interval bez tablet) a Yasmin<\/a> (standardn\u00ed 21denn\u00ed). Yaz je tak\u00e9 schv\u00e1len FDA pro st\u0159edn\u011b t\u011b\u017ek\u00e9 akn\u00e9 u \u017een \u017e\u00e1daj\u00edc\u00edch antikoncepci.\n\nMo\u017enosti na b\u00e1zi desogestrelu.<\/strong> Desogestrel je progestogen t\u0159et\u00ed generace s n\u00edzk\u00fdmi androgenn\u00edmi vedlej\u0161\u00edmi \u00fa\u010dinky. Dostupn\u00e9 jako kombinovan\u00fd COCP Femilon<\/a> (EE 20 mcg + desogestrel 150 mcg).\n\nCOCP na b\u00e1zi cyproteron-acet\u00e1tu pro st\u0159edn\u011b t\u011b\u017ek\u00e9 a\u017e t\u011b\u017ek\u00e9 akn\u00e9.<\/strong> Diane 35<\/a> kombinuje ethinylestradiol s cyproteronacet\u00e1tem (progestin se silnou antiandrogenn\u00ed aktivitou) \u2014 pou\u017e\u00edv\u00e1 se u st\u0159edn\u011b t\u011b\u017ek\u00fdch a\u017e t\u011b\u017ek\u00fdch forem akn\u00e9 a hirsutismu u \u017een vy\u017eaduj\u00edc\u00edch antikoncepci. Podle modern\u00edch doporu\u010den\u00ed (EMA 2013) je pou\u017eit\u00ed omezeno na kr\u00e1tk\u00e9 k\u00fary, pokud standardn\u00ed l\u00e9\u010dba selhala, kv\u016fli vy\u0161\u0161\u00edmu riziku VTE.\n\nProgestogen-only \"mini-pill\".<\/strong> Modern\u00ed desogestrelov\u00e9 POP (75 mcg) udr\u017euj\u00ed potla\u010den\u00ed ovulace a maj\u00ed 12hodinov\u00e9 okno pro vynechanou pilulku. Vhodn\u00e9 pro \u017eeny, kter\u00e9 nemohou u\u017e\u00edvat estrogen \u2014 ku\u0159a\u010dky nad 35 let, koj\u00edc\u00ed \u017eeny, migr\u00e9ny s aurou, hypertenze, anamn\u00e9za VTE nebo BMI > 35. Skladem jako Cerazette<\/a>.\n\nNouzov\u00e1 antikoncepce.<\/strong> Jednor\u00e1zov\u00fd levonorgestrel (Postpone 72, i-pill) \u2014 viz na\u0161e Pilulka po pohlavn\u00edm styku<\/a> kategorie.\n\nJak vybrat.<\/strong> Prvn\u00ed u\u017eivatelka bez rizikov\u00fdch faktor\u016f \u2192 n\u00edzkod\u00e1vkovan\u00fd levonorgestrel COCP (Loette, Ovral-L). PMS, m\u00edrn\u00e9 nad\u00fdm\u00e1n\u00ed, m\u00edrn\u00e9 akn\u00e9 \u2192 drospirenon COCP (Yaz, Yasmin). Nesn\u00e1\u0161enlivost estrogenu \u2192 desogestrel POP (Cerazette). Akn\u00e9 s pot\u0159ebou antikoncepce \u2192 nejprve drospirenon (Yaz), cyproteron (Diane 35) pouze pokud standardn\u00ed l\u00e9\u010dba sel\u017ee.\n\nD\u016fle\u017eit\u00e9.<\/strong> Take the pill at the same time each day \u2014 missed-pill rules differ between COCPs and POPs (read the patient leaflet). VTE risk is small in absolute terms but real \u2014 quit smoking before starting COCPs if over 35. Migraine with aura is an absolute contraindication to COCPs because of stroke risk. Modern guidance: most antibiotics do NOT reduce pill efficacy (only rifampicin \/ rifabutin do); St John's wort, some anticonvulsants, and many enzyme-inducing drugs do reduce efficacy.\n\nAll MedsBase Contraceptive Pill products ship from WHO-GMP certifikovan\u00fdch v\u00fdrobc\u016f<\/strong> s diskr\u00e9tn\u00edm balen\u00edm a jsou kryty na\u0161\u00ed Z\u00e1rukou op\u011btovn\u00e9ho odesl\u00e1n\u00ed<\/a>.","link":"https:\/\/medsbase.com\/cs\/contraceptive-pill-the-pill\/","name":"Antikoncep\u010dn\u00ed pilulka (The Pill)","slug":"contraceptive-pill-the-pill","taxonomy":"product_cat","parent":3502,"meta":[],"menu_order":0,"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat\/3602","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat"}],"about":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/taxonomies\/product_cat"}],"up":[{"embeddable":true,"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product_cat\/3502"}],"wp:post_type":[{"href":"https:\/\/medsbase.com\/cs\/wp-json\/wp\/v2\/product?product_cat=3602"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}