{"id":59279,"date":"2024-02-28T05:49:48","date_gmt":"2024-02-28T05:49:48","guid":{"rendered":"https:\/\/medsname.com\/nafodil\/"},"modified":"2026-04-30T10:16:38","modified_gmt":"2026-04-30T10:16:38","slug":"nafodil","status":"publish","type":"product","link":"https:\/\/medsbase.com\/da\/nafodil\/","title":{"rendered":"Nafodil"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:18px 0;border-radius:4px;\">\n<p style=\"margin:0 0 8px 0;\"><strong>\ud83d\udca1 Hurtigt svar<\/strong><\/p>\n<p style=\"margin:0;\"><strong>Nafodil<\/strong> er <strong>naftopidil<\/strong>, a selective alpha-1D adrenergic blocker used for BPH-related lower urinary tract symptoms (LUTS) \u2014 particularly storage symptoms (urgency, frequency, nocturia). Developed in Japan and widely used in East Asia but less common in Western markets. Typical dose: 25\u201375 mg once daily. Works within days to weeks; distinct side-effect profile vs tamsulosin.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Hvad du f\u00e5r med MedsBase:<\/strong> WHO-GMP certificeret producent \u00b7 Diskret emballage \u00b7 Verdensomsp\u00e6ndende forsendelse \u00b7 1.400+ verificerede <a href=\"https:\/\/medsbase.com\/da\/reviews\/\">kundeanmeldelser<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Hver ordre er d\u00e6kket af vores <a href=\"https:\/\/medsbase.com\/da\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 hvis din pakke ikke ankommer inden for 20 hverdage, sender vi en erstatning.<\/p>\n<h3>Hvorfor bestille fra MedsBase<\/h3>\n<p>Vores generiske medicin kommer fra WHO-GMP certificerede producenter og sendes verdensomsp\u00e6ndende i diskret, neutral emballage \u2014 ingen medicinnavn p\u00e5 pakkens ydre. Kortbetalinger h\u00e5ndteres af en reguleret processor (kontoudtogsbeskrivelser inkluderer en reguleret betalingsprocessor \u2014 aldrig \u201cMedsBase\u201d eller medicinnavn). Crypto og SEPA bankoverf\u00f8rsel accepteres ogs\u00e5. Hver ordre er d\u00e6kket af vores Reshipment Assurance Policy.<\/p>\n<div style=\"background:#f4f8fb;border-left:4px solid #2c7cb0;padding:14px 20px;margin:16px 0;border-radius:4px;font-size:0.95em;\">\n<strong>\ud83d\udd12 Hvorfor bestille fra MedsBase:<\/strong> Verificeret \u00e6gte producentforsyning \u00b7 Diskret verdensomsp\u00e6ndende forsendelse \u00b7 Sikker betaling (kreditkort, krypto) \u00b7 Vurderet 4,9\u2605 af 1.400+ kunder\n<\/div>\n<h2><strong>What Is Nafodil?<\/strong><\/h2>\n<p>Nafodil is a branded generic of <strong>naftopidil<\/strong>, an alpha-1 adrenergic blocker with <strong>preferential selectivity for the alpha-1D receptor subtype<\/strong>. While tamsulosin targets alpha-1A (predominant in prostate smooth muscle), naftopidil targets alpha-1D (predominant in bladder body and spinal cord). This gives naftopidil a different symptomatic profile:<\/p>\n<ul>\n<li>Reliable voiding symptom improvement (weak stream, hesitancy)<\/li>\n<li><strong>Stronger effect on storage symptoms<\/strong> (urgency, frequency, nocturia) than tamsulosin \u2014 a clinical advantage for men whose main complaint is frequent, urgent urination<\/li>\n<li>Lower rate of ejaculatory dysfunction vs tamsulosin (alpha-1A is responsible for ejaculation-related smooth-muscle control)<\/li>\n<\/ul>\n<p>Strengths available: <strong>25 mg, 50 mg, 75 mg<\/strong>. Manufactured by Emcure.<\/p>\n<h2><strong>Klinisk anvendelse<\/strong><\/h2>\n<ul>\n<li><strong>BPH with predominant storage symptoms<\/strong> \u2014 urgency, frequency, nocturia. Naftopidil often outperforms tamsulosin in this subgroup.<\/li>\n<li><strong>Hypertension<\/strong> (off-label in most markets) \u2014 naftopidil has modest blood-pressure lowering effect.<\/li>\n<li><strong>Men on tamsulosin with bothersome ejaculatory side effects<\/strong> \u2014 switching to naftopidil often preserves sexual function.<\/li>\n<\/ul>\n<h2><strong>S\u00e5dan indtages<\/strong><\/h2>\n<ol>\n<li>Swallow the tablet whole with water. Take once daily at roughly the same time each day \u2014 no specific meal timing required.<\/li>\n<li>Typical starting dose: <strong>25 mg en gang daglig<\/strong>. Escalate to 50 mg after 2\u20134 weeks if symptoms persist, then 75 mg maximum.<\/li>\n<li>First dose is ideally taken in the evening \u2014 orthostatic hypotension risk is highest with the initial dose.<\/li>\n<li>Symptomatic improvement begins within <strong>1\u20132 uger<\/strong>, peak effect by <strong>4\u20138 uger<\/strong>.<\/li>\n<li>Do not stop abruptly \u2014 symptoms return. Long-term daily use is typical.<\/li>\n<\/ol>\n<h2><strong>Bivirkninger<\/strong><\/h2>\n<p><strong>Almindelige (\u22651%):<\/strong> dizziness, headache, orthostatic hypotension, somnolence, nasal congestion.<\/p>\n<p><strong>Less common than tamsulosin:<\/strong> retrograde\/reduced ejaculation. This is naftopidil&#8217;s clinical advantage.<\/p>\n<p><strong>Sj\u00e6ldne alvorlige:<\/strong> syncope, priapism, Intraoperative Floppy Iris Syndrome (IFIS) during cataract surgery \u2014 share with ophthalmologist.<\/p>\n<h2><strong>Who Should Not Take Nafodil<\/strong><\/h2>\n<ul>\n<li>Known hypersensitivity to naftopidil or other alpha-blockers<\/li>\n<li>Severe orthostatic hypotension history<\/li>\n<li>Sv\u00e6r leversvigt<\/li>\n<li>Planlagt katarakt-\/glaukomoperation uden at informere \u00f8jenl\u00e6gen<\/li>\n<li>Not indicated for women<\/li>\n<\/ul>\n<h2><strong>L\u00e6gemiddelinteraktioner<\/strong><\/h2>\n<ul>\n<li><strong>Andre alfa-blokkere<\/strong>: additive hypotension \u2014 do not combine.<\/li>\n<li><strong>PDE5-h\u00e6mmere<\/strong>: additive hypotension. Space doses; tadalafil 5 mg daily is often pragmatic.<\/li>\n<li><strong>Antihypertensiva<\/strong>: monitor for excessive blood-pressure drop.<\/li>\n<li><strong>CYP3A4 substrates<\/strong>: naftopidil is extensively metabolised; major interactions uncommon but caution with strong inhibitors.<\/li>\n<\/ul>\n<h2><strong>Naftopidil vs Tamsulosin<\/strong><\/h2>\n<p>Both are selective alpha-blockers for BPH, but they target different receptor subtypes \u2014 tamsulosin prefers alpha-1A (more prostatic), naftopidil prefers alpha-1D (more bladder body). Clinical implications:<\/p>\n<ul>\n<li><strong>Tamsulosin is better<\/strong> for voiding symptoms (weak stream, hesitancy) and in Western evidence-based guidelines as first-line.<\/li>\n<li><strong>Naftopidil is often better<\/strong> for storage symptoms (urgency, frequency, nocturia) and for men with bothersome ejaculatory side effects on tamsulosin.<\/li>\n<li><strong>Regional availability:<\/strong> naftopidil is standard in Japan \/ East Asia; less common in the US \/ EU but widely available in India and other Asian markets.<\/li>\n<\/ul>\n<h2><strong>Opbevaring<\/strong><\/h2>\n<p>Store at room temperature (15\u201330 \u00b0C \/ 59\u201386 \u00b0F), away from moisture and heat. Keep in original blister. Do not use after the printed expiry date.<\/p>\n<h2 id=\"faqs\">Ofte stillede sp\u00f8rgsm\u00e5l<\/h2>\n<h3 class=\"wp-block-heading\">When should I choose naftopidil over tamsulosin?<\/h3>\n<p>Choose naftopidil if your main complaint is urgency, frequency, or nocturia; or if you have had bothersome ejaculation side effects on tamsulosin; or if you prefer a drug with a lower sexual side-effect rate. Tamsulosin remains first-line for Western guidelines for pure voiding-symptom BPH.<\/p>\n<h3 class=\"wp-block-heading\">How fast does Nafodil work?<\/h3>\n<p>Improvement typically begins within 1\u20132 weeks. Peak effect at 4\u20138 weeks. Unlike 5-alpha-reductase inhibitors, naftopidil does not shrink the prostate \u2014 its effect is pharmacological smooth-muscle relaxation.<\/p>\n<h3 class=\"wp-block-heading\">Does naftopidil affect ejaculation?<\/h3>\n<p>Much less than tamsulosin. Naftopidil&#8217;s alpha-1D preference means less effect on bladder-neck closure during ejaculation. This is naftopidil&#8217;s main clinical advantage for men who are sexually active.<\/p>\n<h3 class=\"wp-block-heading\">Can I combine Nafodil with dutasteride?<\/h3>\n<p>Yes \u2014 alpha-blocker + 5-alpha-reductase inhibitor is a standard combination. Naftopidil addresses symptoms; dutasteride shrinks the prostate over 3\u20136 months. Not available as a fixed-dose combination, so take separately.<\/p>\n<h3 class=\"wp-block-heading\">Can I combine Nafodil with tadalafil?<\/h3>\n<p>With caution \u2014 additive blood-pressure lowering. Tadalafil 5 mg daily is often pragmatic and also treats BPH. Space doses by several hours and monitor for dizziness.<\/p>\n<h3 class=\"wp-block-heading\">Does Nafodil affect blood pressure?<\/h3>\n<p>Modest lowering effect. Not sufficient for hypertension monotherapy in most patients, but enough to cause orthostatic dizziness, especially at initiation. First dose should be at bedtime.<\/p>\n<h3 class=\"wp-block-heading\">Why is naftopidil less common in the West?<\/h3>\n<p>Developed by Japan&#8217;s Asahi Kasei Pharma, naftopidil received regulatory approval in Japan (1999) and other East Asian markets but not in the US. Recent studies support its role, particularly for storage-symptom-predominant BPH, and it is increasingly available in generic form globally.<\/p>\n<h3 class=\"wp-block-heading\">Should I tell my ophthalmologist I am on Nafodil?<\/h3>\n<p>Yes \u2014 naftopidil is associated with Intraoperative Floppy Iris Syndrome (IFIS) during cataract surgery, similar to other alpha-blockers. Tell your ophthalmologist before any eye surgery so technique can be adjusted.<\/p>\n<h3 class=\"wp-block-heading\">Relaterede BPH-produkter<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/da\/urimax\/\">Urimax (Tamsulosin 0.2 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/urimax-capsule\/\">Urimax-kapsel (Tamsulosin 0,4 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/tamsuheal\/\">Tamsuheal (Tamsulosin 0,4 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/monolosin\/\">Monolosin (Tamsulosin 0,4 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/dutas-t\/\">Dutas-T (Tamsulosin + Dutasteride)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/urimax-f\/\">Urimax-F (Tamsulosin + Finasteride)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/deetor\/\">Deetor (Dutasteride 0,5 mg)<\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 20px;margin:16px 0;border-radius:4px;font-size:0.9em;\">\n<p style=\"margin:0;\"><strong>\u2695\ufe0f Medicinsk ansvarsfraskrivelse:<\/strong> Denne information er udelukkende til undervisningsform\u00e5l og erstatter ikke l\u00e6gevejledning. Konsulter en kliniker f\u00f8r du p\u00e5begynder, stopper eller \u00e6ndrer medicin. Receptpligtige produkter b\u00f8r kun anvendes under l\u00e6gelig opsyn.<\/p>\n<\/div>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Relaterede alternativer<\/h3>\n<p>Andre produkter inden for <strong>M\u00e6nds sundhed<\/strong> som kunder ogs\u00e5 ser:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/da\/female-up\/\">Female Up<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/super-p-force\/\">Super P Force<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/vega-100\/\">Vega 100<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/cenforce-fm\/\">Cenforce FM<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/zhewitra-oral-jelly\/\">Zhewitra Oral Jelly<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Improves urinary flow<br \/>\n\u2705 Reduces prostate size<br \/>\n\u2705 Lindrer urinvejssymptomer<br \/>\n\u2705 Enhances bladder emptying<br \/>\n\u2705 Minimizes urinary urgency<\/p>\n<p>Nafodil contains Naftopidil.<\/p>","protected":false},"featured_media":59280,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3202,3141,3142],"product_tag":[4667,4668],"class_list":{"0":"post-59279","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-benign-prostatic-hyperplasia-bph-treatment","7":"product_cat-category-overview","8":"product_cat-mens-health","9":"product_tag-nafodil","10":"product_tag-naftopidil","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/product\/59279","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/comments?post=59279"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/media\/59280"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/media?parent=59279"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/product_brand?post=59279"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/product_cat?post=59279"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/product_tag?post=59279"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}