{"id":60195,"date":"2024-02-28T06:37:55","date_gmt":"2024-02-28T06:37:55","guid":{"rendered":"https:\/\/medsname.com\/prazinec\/"},"modified":"2026-05-09T11:38:18","modified_gmt":"2026-05-09T11:38:18","slug":"prazinec","status":"publish","type":"product","link":"https:\/\/medsbase.com\/da\/prazinec\/","title":{"rendered":"Prazinec"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"margin:0 0 22px;padding:16px 20px;background:#fff8e1;border-left:4px solid #f5a623;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px;font-size:18px;color:#2c3e50;\">Quick Answer &mdash; What is Prazinec?<\/h3>\n<div style=\"margin:0;font-size:15px;line-height:1.55;color:#333;\">\n<p><strong>Prazinec<\/strong> er <strong>praziquantel 600&nbsp;mg<\/strong> fra <strong>Sun Pharma<\/strong>. Praziquantel is the WHO Essential Medicine for <strong>schistosomiasis, intestinal flukes, liver flukes, and most cestodes including neurocysticercosis<\/strong>. Standard adult dose for schistosomiasis: <strong>40&nbsp;mg\/kg as a single dose<\/strong>; for tapeworm: 5&ndash;10&nbsp;mg\/kg single dose; for neurocysticercosis: 50&nbsp;mg\/kg\/day in 3 divided doses for 14&ndash;30 days under specialist supervision.<\/p>\n<\/div>\n<\/div>\n<p style=\"font-size:14px;margin:12px 0;\">\ud83d\udcd6 <strong>Fuld guide:<\/strong> <a href=\"\/da\/ivermectin-complete-guide\/\">K\u00f8b Ivermectin til mennesker online \u2014 Dosering, sikkerhed &amp; hvad du skal vide<\/a><\/p>\n<div class=\"medsbase-trust-strip\" style=\"margin:24px 0;padding:14px 18px;background:#f4f4f4;border:1px solid #e1e1e1;border-radius:4px;font-size:14px;color:#444;line-height:1.55;\"><strong>Hvorfor bestille fra MedsBase:<\/strong> \u2713 Sourceret fra <strong>WHO-GMP certificerede producenter<\/strong> \u00b7 \u2713 Diskret emballage \u00b7 \u2713 Verdensomsp\u00e6ndende forsendelse \u00b7 \u2713 <strong>1.400+ kundeanmeldelser<\/strong> p\u00e5 <a href=\"https:\/\/medsbase.com\/da\/reviews\/\">medsbase.com\/reviews<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Hver ordre er d\u00e6kket af vores <a href=\"https:\/\/medsbase.com\/da\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 hvis din pakke ikke ankommer inden for 20 hverdage, sender vi en erstatning.<\/p>\n<h3>Hvorfor bestille fra MedsBase<\/h3>\n<p>Vores generiske medicin kommer fra WHO-GMP certificerede producenter og sendes verdensomsp\u00e6ndende i diskret, neutral emballage \u2014 ingen medicinnavn p\u00e5 pakkens ydre. Kortbetalinger h\u00e5ndteres af en reguleret processor (kontoudtogsbeskrivelser inkluderer en reguleret betalingsprocessor \u2014 aldrig \u201cMedsBase\u201d eller medicinnavn). Crypto og SEPA bankoverf\u00f8rsel accepteres ogs\u00e5. Hver ordre er d\u00e6kket af vores Reshipment Assurance Policy.<\/p>\n<h2 class=\"wp-block-heading\">What is Prazinec?<\/h2>\n<p><strong>Prazinec<\/strong> is praziquantel 600&nbsp;mg from <strong>Sun Pharma<\/strong>. Praziquantel is one of the most important drugs in tropical medicine &mdash; the global standard for schistosomiasis (which affects roughly 240 million people worldwide), and the agent of choice for most cestode and trematode infections. WHO mass-drug-administration programmes have used praziquantel to treat over a billion people since the 1990s.<\/p>\n<h2 class=\"wp-block-heading\">Virkningsmekanisme<\/h2>\n<p>Praziquantel <strong>increases calcium permeability<\/strong> across the parasite tegument (outer covering), causing rapid sustained muscle contraction. This paralyses the worm and exposes its surface antigens to host immune attack &mdash; a one-two punch of pharmacological paralysis followed by immune-mediated killing. The mechanism explains why praziquantel works so well in immunocompetent patients and is somewhat less effective in heavily immunosuppressed hosts.<\/p>\n<p>Oral bioavailability is good (~80%) but first-pass hepatic metabolism is heavy &mdash; only about 25% reaches systemic circulation as active drug. Plasma half-life is 1&ndash;1.5 hours.<\/p>\n<h2 class=\"wp-block-heading\">Prazinec indications and dose<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;font-size:14px;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Indikation<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Dosis<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Doseringsskema<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Schistosomiasis (S. mansoni, S. haematobium, S. japonicum)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">40&nbsp;mg\/kg<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Single dose (S. japonicum: 60&nbsp;mg\/kg)<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Intestinal tapeworm (Taenia saginata, T. solium)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">5&ndash;10&nbsp;mg\/kg<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Enkeltdosis<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Hymenolepis nana<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">25&nbsp;mg\/kg<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Single dose, repeat at 1 week<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Liver flukes (Clonorchis, Opisthorchis)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">25&nbsp;mg\/kg TID<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">For 1 day (75&nbsp;mg\/kg total)<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Lung fluke (Paragonimus)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">25&nbsp;mg\/kg TID<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">For 2 days<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Neurocysticercosis (specialist)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">50&nbsp;mg\/kg\/day in 3 doses<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">For 14&ndash;30 days WITH steroid cover<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Take with water or a soft drink during or shortly after a meal. Tablets have a bitter taste &mdash; do not chew. Children &gt; 4 years: same weight-based dosing applies.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;line-height:1.55;color:#444;\"><strong>Neurocysticercosis is a specialist diagnosis.<\/strong> Praziquantel for CNS cysticercosis must be given with concurrent corticosteroid (typically dexamethasone) to suppress the inflammatory response to dying cysts &mdash; otherwise raised intracranial pressure can be catastrophic. Imaging (MRI brain) is mandatory before treatment. Do not self-treat suspected neurocysticercosis.<\/div>\n<h2 class=\"wp-block-heading\">Bivirkninger<\/h2>\n<ul>\n<li><strong>Almindelige:<\/strong> abdominal discomfort, nausea, malaise, headache, dizziness, drowsiness &mdash; usually within first 24&nbsp;hours, often related to dying parasites rather than the drug<\/li>\n<li><strong>Mindre almindelige:<\/strong> urticaria, fever, transient eosinophilia rebound<\/li>\n<li><strong>Sj\u00e6ldne:<\/strong> bradycardia, transient transaminase rise<\/li>\n<li><strong>Neurocysticercosis-specific:<\/strong> headache, seizures, raised intracranial pressure as cysts die &mdash; the reason for steroid cover<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">L\u00e6gemiddelinteraktioner<\/h2>\n<ul>\n<li><strong>St\u00e6rke CYP3A4-inducerende midler<\/strong> (rifampicin, carbamazepine, phenytoin, phenobarbital) &mdash; reduce praziquantel levels significantly; avoid combination or use alternative<\/li>\n<li><strong>St\u00e6rke CYP3A4-h\u00e6mmere<\/strong> (ketoconazole, ritonavir, cimetidine) &mdash; raise levels; reduce dose if combination unavoidable<\/li>\n<li><strong>Dexamethasone<\/strong> &mdash; reduces praziquantel levels by ~50%, but the combination is still required for neurocysticercosis (clinical effect retained)<\/li>\n<li><strong>Chloroquine<\/strong> &mdash; reduces praziquantel levels modestly<\/li>\n<li><strong>Grapefrugtjuice<\/strong> &mdash; raises levels; avoid during treatment<\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;line-height:1.55;color:#444;\"><strong>Graviditet og amning.<\/strong> Albendazol og mebendazol frar\u00e5des i f\u00f8rste trimester (dyrestudier viser teratogen effekt). Brug er acceptabelt i 2.\/3. trimester ved moderat til sv\u00e6r ormebyrde. Data for ivermectin under graviditet er begr\u00e6nsede, men geringsfrygtende i WHOs massebehandlingsprogrammer; undg\u00e5 i f\u00f8rste trimester, hvis der findes alternativer. Praziquantel og pyrantel er kompatible med graviditet.<\/div>\n<h2 class=\"wp-block-heading\">Kontraindikationer<\/h2>\n<ul>\n<li>Hypersensitivity to praziquantel<\/li>\n<li>Ocular cysticercosis &mdash; treatment can destroy the eye; specialist surgical assessment first<\/li>\n<li>Children &lt; 4 years &mdash; safety not established<\/li>\n<li>Sv\u00e6r leversvigt<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Opbevaring<\/h2>\n<p>Store Prazinec below 30&deg;C in the original blister, protect from light and moisture.<\/p>\n<h3 class=\"wp-block-heading\">Hvorfor bestille fra MedsBase<\/h3>\n<p>Prazinec is supplied from a <strong>WHO-GMP certificeret producent<\/strong>, pakket diskret og sendt worldwide. Hver ordre er d\u00e6kket af vores <a href=\"https:\/\/medsbase.com\/da\/medsbase-re-shipment-assurance-policy\/\">Reshipment Assurance Policy<\/a> \u2014 du b\u00e6rer aldrig omkostningerne ved en mistet pakke.<\/p>\n<h2 id=\"faqs\">Ofte stillede sp\u00f8rgsm\u00e5l<\/h2>\n<h3 class=\"wp-block-heading\">How quickly does Prazinec work?<\/h3>\n<p>Schistosomes and most flukes are paralysed within hours. Egg shedding stops over the following 1&ndash;2 weeks. For schistosomiasis, urine or stool testing at 4&ndash;6 weeks confirms cure.<\/p>\n<h3 class=\"wp-block-heading\">Why take Prazinec with food?<\/h3>\n<p>Food increases bioavailability roughly 2-fold. For most indications this is helpful. Do not chew &mdash; the bitter taste is intense.<\/p>\n<h3 class=\"wp-block-heading\">Will I see worms in my stool after?<\/h3>\n<p>For tapeworm, expect partial passage of fragmented proglottids over the days following the dose &mdash; the worm is partly digested by host enzymes after praziquantel has done its job. For schistosomiasis the eggs are microscopic; you won&rsquo;t see worms.<\/p>\n<h3 class=\"wp-block-heading\">Is Prazinec safe in pregnancy?<\/h3>\n<p>WHO endorses praziquantel use in pregnancy where infection is symptomatic or the worm burden is significant. The first trimester is preferred to be avoided where alternatives exist. Consult a clinician for individualised guidance.<\/p>\n<h3 class=\"wp-block-heading\">Can children take Prazinec?<\/h3>\n<p>Yes from age 4 with the same weight-based dosing as adults. WHO mass-drug-administration programmes routinely treat school-age children for schistosomiasis with single-dose praziquantel.<\/p>\n<h3 class=\"wp-block-heading\">What if I have neurocysticercosis?<\/h3>\n<p>Treatment requires neurology supervision. MRI imaging, concurrent dexamethasone, and (for ocular involvement) ophthalmology assessment are mandatory. Self-treatment can be catastrophic &mdash; the brain inflammation from dying cysts can cause raised intracranial pressure.<\/p>\n<h3 class=\"wp-block-heading\">Does praziquantel treat ascaris or pinworm?<\/h3>\n<p>No. Praziquantel covers cestodes (tapeworms) and trematodes (flukes including schistosoma). For nematodes (ascaris, pinworm, hookworm, whipworm) use albendazole or mebendazole.<\/p>\n<h3 class=\"wp-block-heading\">Can I drink alcohol after the dose?<\/h3>\n<p>Avoid alcohol on the day of treatment &mdash; it amplifies the dizziness and drowsiness common in the first 24&nbsp;hours.<\/p>\n<h3 class=\"wp-block-heading\">Why might Prazinec fail?<\/h3>\n<p>Most common reasons: under-dosing (especially in heavy patients), reinfection from continued exposure (re-entering schistosomiasis-endemic water bodies), or co-administration with strong CYP3A4 inducers (rifampicin, anticonvulsants) that reduce drug levels.<\/p>\n<h3 class=\"wp-block-heading\">Should I retest after treatment?<\/h3>\n<p>For schistosomiasis, retest with urine or stool at 4&ndash;6 weeks. For intestinal tapeworm, retest at 1 and 3 months. For neurocysticercosis, repeat MRI at 3&ndash;6 months under specialist guidance.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Andre Antiparasit\u00e6re L\u00e6gemidler<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/da\/niclosig\/\">Niclosig (niclosamide 500 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/prazinec\/\">Prazinec (praziquantel 600 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/abd-400-albendazole\/\">ABD 400 (albendazol 400 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/mebex\/\">Mebex (mebendazole)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/tinvista\/\">Tinvista (tinidazole)<\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:22px 0;border-radius:4px;font-size:14px;color:#444;\"><strong>Medicinsk ansvarsfraskrivelse.<\/strong> Denne side er kun til uddannelsesm\u00e6ssige form\u00e5l og erstatter ikke professionel medicinsk r\u00e5dgivning. Konsulter en kvalificeret kliniker, f\u00f8r du p\u00e5begynder enhver antihelmintisk behandling, is\u00e6r hvis du er gravid eller ammer, immunsupprimeret, behandler et barn under 2 \u00e5r, eller hvis symptomerne vedvarer efter en behandlingsperiode. Eosinofili, v\u00e6gttab, vedvarende mavesmerter eller rejserelaterede symptomer kr\u00e6ver klinisk evaluering. Alvorlige parasitsygdomme (neurocysticerkose, strongyloides hyperinfektion, schistosomiasis med organdeltagelse) h\u00e5ndteres af specialister.<\/div>","protected":false},"excerpt":{"rendered":"<p>Prazinec (praziquantel 600 mg, Sun Pharma) \u2014 WHO essential medicine for schistosomiasis, intestinal and liver flukes, and most cestodes. Standard 40 mg\/kg single dose for schistosomiasis.<\/p>","protected":false},"featured_media":60196,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3342,3856],"product_tag":[4819,4596],"class_list":{"0":"post-60195","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-general-health","8":"product_cat-threadworm-treatment","9":"product_tag-prazinec","10":"product_tag-praziquantel","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/product\/60195","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/comments?post=60195"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/media\/60196"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/media?parent=60195"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/product_brand?post=60195"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/product_cat?post=60195"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/product_tag?post=60195"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}