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Temozol<\/strong> is an oral capsule from Cipla containing temozolomide<\/strong> p\u00e5 20 mg<\/strong> — an oral alkylating cytotoxic agent and the standard chemotherapy for glioblastoma multiforme (GBM)<\/strong> og anaplastic astrocytoma<\/strong>. Standard regimen: concurrent<\/strong> with radiotherapy (75 mg\/m² daily for 6 weeks), then maintenance<\/strong> 150–200 mg\/m² daily for days 1–5 of each 28-day cycle for 6 cycles (Stupp protocol). Tag p\u00e5 tom mave<\/strong> at the same time each day, with antiemetic (ondansetron) 1 hour before. Mandatory: PCP-profilakse<\/strong> with co-trimoxazole during radiotherapy phase. FBC weekly during concurrent phase, then before each maintenance cycle.<\/p>\n<\/div>\n \ud83d\udce6 Hver ordre er d\u00e6kket af vores Reshipment Assurance Policy<\/strong><\/a> \u2014 hvis din pakke ikke ankommer inden for 20 hverdage, sender vi en erstatning.<\/p>\n Temozol is an oral capsule from Cipla containing temozolomide<\/strong> (20 mg). Temozolomide is an oral alkylating cytotoxic agent of the imidazotetrazine class. It crosses the blood-brain barrier (CSF concentration ~30% of plasma) and is the only oral cytotoxic with proven survival benefit in glioblastoma multiforme. Standard combination with radiotherapy (the “Stupp protocol”, 2005) extended median GBM survival from 12 months to 15 months and 2-year survival from 11% to 27%.<\/p>\n Almindelige:<\/strong> nausea, vomiting (mostly preventable with ondansetron), fatigue, anorexia, constipation, headache, alopecia.<\/p>\n Vigtigt:<\/strong><\/p>\nWhat Is Temozol?<\/h2>\n
\u2014 det forst\u00e6rker den normale fysiologiske respons snarere end at udl\u00f8se en kunstigt.<\/h2>\n
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Dosage (Stupp protocol)<\/h2>\n
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L\u00e6gemiddelinteraktioner<\/h2>\n